\w v.s. 
 
 3571. Scheme of a System of Modern 
 Medicine. To be edited by William Osier, 
 la. 8°. Phila ., n.d. 
 
 Two annotated copies, with correspondence 
 from Dr. McCrae and others, 1905-8, bound in. 
 
 FROM 
 
 the library 
 
 OK 
 
 SIR WILLIAM OSLER ♦ Bart. 
 
 OXFORD 
 

p 
 
u 
 
NO TB. 
 
 This work is planned to appear in seven octavo volumes, 
 averaging 800 pages each, with about 5/+0 words to the page. 
 # is essential that articles should deal with their topics as con¬ 
 cisely as possible without sacrifice of completeness. 
 
 Especial attention should be given to the adoption and main¬ 
 tenance of a clear and simple subdivision of material in the 
 manuscript, for which the following order is suggested: Etiology , 
 Special Pathology, Symptoms , Diagnosis, Prognosis, Treat¬ 
 ment and Sequela\ 
 
 Illustrations are desired where necessary for the elucidation 
 of the text and are to be included in the number of pages 
 allotted. They should be allowed for as occupying one-third 
 of a page each upon the average. Text references should be 
 made by footnotes. 
 
807 St. Paul Street. 
 CONSULTATION HOURS 
 
 3-6 P. M. 
 
 BALTIMORE 
 
 
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DR. THOMAS MCCRAE, ^ 
 807 St. Paul Street, 
 
 CONSULTATION HOURS 
 3-5 P. M. 
 
 Oopy. 
 
 BALTIMORE, 
 
 National Hospital, 
 
 Queen Square, 
 
 Bloomsbury, V/. C., 
 London. 
 
 Dear Dr. McCrae: 
 
 You and Professor 0 b 1 er accused me of 
 having forgotten some earlier correspondence I had with 
 you, on the articles I am to write for the System of 
 Medicine. I believe I have now solved the matter. I 
 
 wrote some time ago to the publishers asking them to 
 send me the authorship cpoies of the volumes which have 
 already appeared, and have just had a reply to say they 
 had already sent them to Dr. W. Gordon Holmes, Oakley 
 House, Oakley Crescent, London. This is not me but I 
 now presume that it was with him that you were in communi¬ 
 cation. My work has been delayed by a slight illness, 
 but it is now practically finished; I have found it dif¬ 
 ficult to get "Diseases of the Peripheral Nervous System" 
 into 50 pages - very little more than is devoted to lead 
 Poisoning in Vol. I, and write with the fullness of the 
 articles which have already appeared. 
 
 I am yours sincerely, 
 
 Gordon Holmes. 
 
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Frederick T. Lord, M.D. 
 
 305 Beacon Street 
 Boston 
 
 June 14, 1907. 
 
 Dr. William Osier, 
 
 Regius Professor of Medicine 
 Oxford, England. 
 
 Dear Dr. osier, 
 
 I am in receipt of your letter of June 1st., asking me to hurry 
 with the section on the pleura, and shall be glad to do all in my 
 power to fall in with your plans for the volume. I am also writing 
 Dr. LIcCrae asking him to let me know when he would like the copy. 
 
 I was sorry to miss seeing you on your last visit and shall hope 
 to see you the next time you come. 
 
 With kind regards. 
 
 Sincerely yours 
 
Kainn't % Iflatrcgrh, 1ft. 13 . 
 
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 -7 
 
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IUtIu'X'1 T&itbcatk , ift. 5. 
 
 it‘I State Street 
 Cfyirngt* 
 
 June 19, 19 $7. 
 
 Dr. William Osier, 
 
 Regius PofesBor of Medicine, 
 
 Oxford, England. 
 
 Dear Dr. Osier:- 
 
 I have not yet received the letter which Me Crea said you in** 
 tended writing me. A note from him in reply to one from me says you 
 mentioned having written me already. As I am desirous to have my manu* 
 script please you I am util! holding the same for your suggestions and 
 shall do so unless notified by Me Crea to send it to him. 
 
 I van dreadfully disappointed not to see you ir. Washington. 
 Hoping you and your faraily are well,and thanking you for your kind 5 words 
 of commendation of ny book on the lungs, I remain, 
 
 Yours cordially, 
 
 v^v / ^ 
 
BALTIMORE, 
 
 XJ 
 
 DR. THOMAS MCCRAE, 
 807 St. Paul Street. 
 
 CONSULTATION HOURS, 
 
 3-5 P. M. 
 
 7d. 07 
 
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R. THOMAS MCCR AE, 
 307 St. Paul Street, 
 
 CONSULTATION HOURS 
 
 BALTIMORE. JuH0 7, 1907 
 
 3-6 P. M. 
 
 Dear Dr. Osier: 
 
 As Novy did not discuss the matter of 
 treatment in his article on food poisons in Vol. 1, 
 
 I have suggested that he give us ashortEdition for 
 the next printing. There is nearly a pa e available, 
 on which I should think he could get in all that is 
 necessary. I hope this meets with your approval. 
 
 In regard to the question of tumors of 
 the membranes of the c^ord, might it not be a good plan 
 for you to write Buzzard and Branwell about it? 
 
 Buzzard takes the disease of the c^ord and Branwell of 
 the meninges. You will remember that we have not any 
 section on the surgery of the cVord. 
 
 In regard to the discussion of arthritis 
 deformans at the British Medical, I wrote to Luff, r/ho 
 openS 7 the discussion, as to any suggestion in reference 
 to any special phase of the subject that he might wish me 
 to deal with, but his answer does not give any suggestion. 
 Do you think of any special feature that it might be well 
 for me to lay to lay special stress on. 
 
 Mr 
 
 

 
 
 
 
 
 
 
 
 
 
 
R. THOMAS MCCRAE, 
 807 St. Paul Street, 
 
 CONSULTATION HOURS 
 
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BALTIMORE, Juljf 5, 1907 
 
 R. THOMAS MCCR AE. 
 807 St. Paul Street, 
 
 CONSULTATION HOURS 
 
 Dear Dr, Oslor. 
 
 The question of some of the sections of tu¬ 
 berculosis comes up, as Brown has really done nothing but 
 
 pulmonary tuberculosis. I have arranged with Lord to 
 
 take tuberculosis of the pleura, and I suppose later on 
 we can got Young to deal with the kidney. My impression 
 is that s up^o^^i^ Brown w o t* j> d discuss tuberculous peri¬ 
 tonitis v/e notified Rolleston that he would not require to 
 discuss the tuberculous peritonitis. I cannot lay my hand 
 on the memorandum about it, although it is here somewhere. 
 It might be well if you could find out from Rolleston if 
 he has done anything on it, and if not try and get him to 
 write a short section. I am sorry to be so indefinite. 
 
 and I may be able to lay my hand on that before I go. 
 
 Sljflbi Ccj - 
 
 Churchman has practically finished the^article and prom¬ 
 
 ises it tomorrow morning. 
 
 Tfith kind regards, 
 
 Yours very truly 
 
 Jfa CrtWM ru - 
 
 jsh(- yoKx faith avM'i/c^ & Cdiic 
 
 {itUa'iIx ifiu 7K(/7< ctfi- 
 
 CUVDlt/ld LcoXibj Ihr 
 
 Ifa-X 
 
 
I 
 
 CONTENTS 
 
 OF A 
 
 SYSTEM 0T MODEEN MEDICINE. 
 
 VOLUME I. 
 
 PART i. 
 
 THE DEVELOPMENT OF INTERNAL MEDICINE. 
 
 
 1. GENERAL L\Yr(I)L ! CTIOX. THE PATHOLOGY OF INFECTION, 
 IM.MtMTY, 'H MOHS, CANCER, Etc. [ Pages] 
 
 
 Bt 
 
 2. HEREDITY AND DISEASE. 
 
 [if Pages] 
 
 PART II. 
 
 DISEASES CAUSED BY PHYSICAL AGENTS. 
 
 1. HEAT AND COLD 
 Bt 
 
 2. LIGHT. 
 
 By 
 
 3. ELECTRICITY. 
 
 By 
 
 3f 
 
 Pages] 
 
 \T 
 
 [ Pages] 
 
 3i 
 
 [ Pages] 
 
[ Pages] 
 
 J 
 
 . 2 
 
 A SYSTEM OF MODERN MEDICINE.— VOLUME I- 
 
 4. VARIATIONS IN ATMOSPHERIC PRESSURE. 
 
 By 
 
 5. MOUNTAIN SICKNESS. 
 
 By 
 
 DISEASES CAUSED BY CHEMICAL AGENTS. 
 
 1. LEAD. ttf* - OV Pages] 
 
 2. ARSENIC. 
 
 3. OTHER METALLIC POISONS, MERCURY, PHOSPHORUS, Etc. 
 
 4. CARBON MONOXIDE AND DIOXIDE. 
 
 By 
 
 By 
 
 
 [ la Pages] 
 
 [ 2 C' Pages] 
 
 [ >o Pages] 
 
 By 
 
 
 
 DISEASES CAUSED BY ORGANIC AGENTS. 
 
 1. ALCOHOL. 
 
 2. OPIUM. 
 
 By 
 
 By 
 
 3. COCAINE, Etc 
 
 By 
 
 [ j Pages] 
 
A SYSTEM OF MODERN MEDICINE.—VOLUME I. 
 
 3 
 
 ' 4. FOODS—MILK, FISH, MEAT, Etc. 
 
 By 
 
 'VVA 
 
 [ TjO Pages] 
 
 1 
 
 5. VENOMS. 
 
 
 C\ 
 
 By 
 
 K 
 
 
 [tO Pages] + 
 
 AUTO-INTOXICATIONS—NORMAL AND PATHOLOGICAL. ZA 
 
 By //- 
 
 &• 
 
 [){i 
 
 INTOXICATIONS IN GENERAL. PATHOLOGY. 
 
 By 
 
 V 
 
 . X. 1- o £/- 
 
 DISEASES CAUSED BY VEGETABLE PARASITES. 
 
 1. ASPERGILLUS. 
 
 By 
 
 
 
 2. ACTINOMYCES. 
 
 By 
 
 3. BLASTOMYCETES. 
 
 By 
 
 5 
 
 nr 
 
 [ Pages] 
 
 
 [ Pages] I $ 
 
 [ Pages] 
 
 
 5 (4 *1 
 
 !*** 
 
 DISEASES CAUSED BY PROTOZOA. 
 
 M. 4. h^v>< /c> 
 
 1. MALARIA. - .X. IpV- [4° Pages] ^ 
 
 . By 
 
 A 5w ■ - "7 
 
 
 2. TRYPANOSOMIASIS. 
 
 By 
 
 4 i 
 
 f 7 }Pages] 
 
 3. AM(EBIC DYSENTERY. 
 
 By 
 
 $&vu f . 
 
 - c*—; 
 
 _Pi DISEASES CAUSED BY ANIMAL PARASITES. 
 
 By 
 
 
 /OXJ_ 
 
 Uxsk 
 
 Hi ^ . c. / 
 
4 
 
 u 
 
 A SYSTEM OF MODERN MEDICINE.— VOLUME I 
 
 PART III. 
 
 NUTRITION. 
 
 GENERAL CONSIDERATIONS OF METABOLISM, NORMAL AND IN 
 
 DISEASE. 
 
 By 
 
 
 [fO-V Pages] * 
 
 DISEASES OF NUTRITION. 
 
 1. DIABETES MELLITUS. 
 
 [ S~C Pages] 
 
 By 
 
 2. DIABETES INSIPIDUS. 
 
 By 
 
 IO Pages] 
 
 3. GOUT. 
 
 [ U o Pag**] 
 
 By 
 
 
 
 4. OBESITY. 
 
 [ to 
 
 r 
 
 Ry 
 
 
 
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 By 
 
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 By 
 
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 A SYSTEM OF MODERN MEDICINE. VOLUME II. 
 
 VOLUME n. 
 
 INFECTIOUS DISEASES. 
 
 L TYPHOID AND TYPHUS FEVERS. 
 By 
 
 [2 fiT Pages] 
 
 /0- 
 
 2. SMALLPOX, Va eCIMATIO.X A ND VARICELLA 
 
 [ Pnges] 
 
 
 / 
 
 3. SCARLET FEVER,; MEASLES, RUBELLA AND DIPHTHERIA. [ Pages] 
 
 By 
 
 
 
 4. RELAPSING FEVER. 
 
 By 
 
 [ S p ages] 
 
 5. MUMPS. 
 
 [ /o p »?es] 
 
 By 
 
 <7 
 
 6. WHOOPING COUGH. 
 
 By 
 
 [ /o Pages] 
 
 7. INFLUENZA. 
 
 
 [ -2<J Pages] 
 
 By / C / l .0 is 
 
 Xcr^I. - 
 
 
 8. DENGUE. 
 
 By 
 
 
 
 ». CEREBRO SPINAL FEVER. 
 
 By 
 
 [ S’ Pages] 
 
 Tk Gy <Sf ■ * • ~ 
 
 [ ir Pages] 
 
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 A SYSTEM OF MODERN MEDICINE.— VOLUME II 
 10. PNEUMONIA. 
 
 11. SEPTICEMIA. 
 
 By 
 
 By 
 
 
 
 
 [/VT Pages] 
 
 [ >5* Pages] 
 
 
 12. RHEUMATIC FEVER. 
 
 By 
 
 13. ASIATIC CHOLERA. 
 
 By 
 
 , %4aI/Uv? * 
 
 14. YELLOW FEVER. 
 
 By 
 
 \t ’ 
 
 CoAYvii * 
 
 15. PLAGUE. 
 
 By 
 
 
 16. EPIDEMIC DYSENTERY 
 By 
 
 S by 
 
 [ X. Pages] 
 
 [ 2^ Pages] 
 
 
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 o^U< • Af - 7 
 
 <v 
 
 
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 A SYSTEM OF MODERN M ED ICI NE.-VO L U M E 
 
 IWJ 
 
 Kfl 
 
 VOLUME ill. 
 
 TAUT I. 
 
 INFECTIOUS DISEASES Continued. 
 
 I. MALTA FEVER. 
 
 By 
 
 -I t V 
 
 T 
 
 oM' 
 
 U ' 2. BERI-BERI. 
 
 > 
 
 Ev 
 
 1w. M.* 4 " 
 
 /ftuu f — 
 
 !i‘ 
 
 3. ANTHRAX. 
 
 By 
 
 i A t ■ w f 
 
 4. HYDROPHOBIA. 
 
 5. TETANUS. 
 
 6. GLANDERS. 
 
 By 
 
 By 
 
 By 
 
 P-\“ l 
 
 {Uy. 
 
 . . „ 1 id of 
 
 
 
 7. SYPHILIS. 
 
 By 
 
 
 8. GONORRHIEAL INFECTION. 
 
 By 
 
 't<U 
 
 9. TUBERCULOSIS. 
 
 By 
 
 7 / < 
 
 I Vw / ) )Yu 
 
 TIT. 7 
 
 [ r Pages] 
 
 [ TO Pages] 
 
 [ >o Pages] 
 
 [ to Pages] 
 
 [ /o Pages] 
 
 [ S’ Pages] 
 
 [ SAJ Pages] 
 
 [ >r Pages] 
 
 [ Zoo Pages] 
 
8 A SYSTEM OF M ODER N M E DIC1N E.—Y 0 LXJ M E III. 
 
 10. LEPROSY. 
 
 By 
 
 
 6 oL i 
 
 [ tS Pages] 
 
 11 . FEBRICULA, WEIL’S DISEASE, Etc. 
 By 
 
 [ JLO Pages] 
 
 9 
 
 ,JL~ 
 
 PART II. 
 
 DISEASES OF THE RESPIRATORY TRACT. 
 
 [ ir Pages] 
 
 1. PHYSICS OF RESPIRATION. 
 
 By 
 
 
 c 
 
 2. PHYSICAL SIGNS OF DISEASES OF RESPIRATORY TRACT [ Pages] 
 
 7 • 
 
 '2 
 
 3 . DISRA SESDF THE NUSE." • 
 
 By _ yU. ? i * 
 
 \ mrivm nr Tinvni 4 i im-y_ 
 
 By 
 
 [ Pages] 
 
 [ Vt> Pages] 
 
 5. DISEASES OF THE LARYNX. 
 
 By 
 
 6. DISEASES OF THE BRONCHI. 
 By 
 
 1 Vt' 
 
 [ Xo Pages] 
 
 I W C_ P /->0LvV -t 
 
 fo.n 
 
 [ (1^ Pages] 7il 
 
 
 7. DISEASES OF THE LUNGS, 
 
 a 
 
 [ / i r Pages] 
 
A SYSTEM OF MODERN MED TO TNE.—VO L UM E IV. 
 
 9 
 
 IS\ 
 
 Kt 
 
 8. DISEASES OF THE PLEURA 
 By 
 
 tfh.o [ teo Pages 1 
 
 u- J *+ +•• ** * i/y*M 
 
 9. DISEASES OF THE MEDIASTINUM. 
 
 B y i ^ G. c *■ ) 
 
 [ c/ 0 Pages] 
 
 VOLUME IV. 
 
 PART I. 
 
 If- 
 
 DISEASES OF THE CIRCULATORY SYSTEM. 
 
 it 
 
 1. THE PHYSICS OF VASCULAR DISEASE, MECHANICAL 
 OlY STRAIN-, Exc.^ 1 
 
 
 
 /< 
 
 2. DISEASES OF THE PERICARDIUM, y. I [ ^ p ages ] 
 
 By 
 
 )*!< 
 
 3. ENDOCARDITIS, VALVULAR DISEASE, HYPERTROPHY AND 
 
 DILATATION. [* 0o Pages] 
 
 By tv' 5 / . 
 
 4. DISEASES OF THE MYOCARDIUM AND CARDIAC NEUROSES. (j« Pages] 
 BY ' ' 
 
 
 5. CONGENITAL CARDIAC DISEASE. 
 
 By 
 
 
 [ ^ges] 
 
 6. DISEASES OF THE ARTERIES AND ANEURISM. ' /vrTages] 
 
 ^ ' 
 


 
 A SYSTEM OF MODERN MED JO IN E.-V 0 LU ME V. 
 
 11 
 
 4. DISEASES OF THE PHARYNX AND TONSILS. 
 Bv 
 
 [7-o Pages] 
 
 
 
 +r~ &' 
 
 5. DISEASES OF THE (ESOPHAGUS. 
 * By 
 
 ^f 1 . 
 
 i. 
 
 c 
 
 
 , 4^' 
 
 M' tfy^ 
 
 6. DISEASES OF THE STOMACH. 
 By 
 
 J **. Y '* 
 
 7. DISEASES OF THE INTESTINES. 
 By 
 
 ‘Vll *. ,4- Z 
 
 J ft 
 
 0 i <+ 
 
 [xf Pages] 
 
 [ 2«rx> Pa ge s ] 
 
 [T-M'Pages] 
 
 .NIB . C 
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 t ' 8. DISEASES OF THE LIVER. 
 
 >6l 
 
 [ / S^» Pages] 
 
 “V 
 
 9. DISEASES OF THE PANCREAS. 
 
 [« 
 
 .a 
 
 o > 
 
 u 
 
 By 
 
 (TL 
 
 <X- 
 
 10. DISEASES OF THE PERITONEUM. 
 By 
 
 #*c- 
 
 [»' 
 
 11. ENTEROPTOSIS. 
 
 By 
 
 X'< 3 ° 
 
 fliA/jts UyT' 
 
 I 
 
 /^K- /S?T^vU. 
 
 [ STJ Pages] 
 
 [ nr Pages] 
 
 [ to Pages] 
 
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 v- 
 
12 
 
 
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 A SYSTEM OF MODERN M E DICINE . — V O L U M E VI. 
 
 VOLUME VI. 
 
 PART I. 
 
 DISEASES OF THE KIDNEY. , 
 
 ikdj 
 
 jfeuwr'' 
 
 <\>d' 
 
 f yj.i >. 8 
 
 \ 
 
 T-. MALFORMATIONS, Etc. 
 
 By 
 
 £ CIRCULATORY DISTURBANCES. 
 By 
 
 3. ANOMALIES OF SECRETION. 
 
 By 
 
 4. UR/EMIA. 
 
 r 
 
 By 
 
 7 ^YvUsV% ♦ ^ I 
 
 [ Pages] 
 
 [ 7L* Pa ges] 
 
 [ 4 o Pages] 
 
 [ To P#i 
 
 5. ACUTE NEPHRITIS. 
 
 By 
 
 6 . CHRONIC NEPHRITIS. 
 
 By 
 
 7. AMYLOID. 
 
 By 
 
 S. PYELITIS. 
 
 By 
 
 9. HYDRONEPHROSIS. 
 
 By 
 
 Pages] 
 
 [ 7 r Pages] 
 
 [ /{j Pages] 
 
 [ Pages] 
 
tvY-T . 
 
 7l L d 
 
 [ll 1 
 
 (9 1 
 
 *- 7 . 
 
 C<rC{<-^ ? 
 
 J (Z *. 
 
 2 POc^Z.-- 
 
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A SYSTEM OF MODERN M EDI CINE— VO L TJME VI. 13 
 
 10 . STONE IX KIDNEY. 
 
 By 
 
 fan. 
 
 'jJU / 11 . TUMORS, CYSTS. 
 
 By 
 
 12 . ABSCESS. 
 
 By 
 
 
 PART II. 
 
 DISEASES ASSOCIATED WITH INTERNAL SECRETION. 
 
 1 . SUPRARENALS. 
 
 By 
 
 [ 7$' Pages] 
 
 [ '•vY' Pages] 
 
 [ to Pages] 
 
 [if o Pages] 
 
 
 2. THYROID. 
 
 By 
 
 3. THYMUS. (>-r ■ 
 
 By 
 
 
 % 
 
 o of 
 
 4. LYMPHATICS. 
 
 5. MYXGEDEMA. 
 
 By 
 
 By 
 
 [ i* u Pages] 
 
 [>* 1>a ? es l 
 
 [ Pages] 
 
 [ ZC Pages] 
 
 ftp ! 6 . CRETINISM. 
 
 By 
 
 VM 
 
 
 7. ACROMEGALY. 
 
 By 
 
 [ 1>a S es l 
 
 [ /o Pages] 
 
14 
 
 A SYSTEM OF MODERN MEDICINE.— VOLUME VI 
 
 part III. 
 
 DISEASES OF OBSCURE CAUSATION. 
 
 1. HODGKIN’S DISEASE. 
 
 By 
 
 
 2. ARTHRITIS DEFORMANS. 
 
 By 
 
 % tyU--Cy** ’ 
 
 3. OSTEOMALACIA. 
 
 By 
 
 hni 
 
 * 
 
 PART IV. 
 
 DISEASES OF THE MUSCLES 
 
 By 
 
 VASOMOTOR AND TROPHIC DISORDERS. 
 
 1 . RAYNAUD’S DISEASE AND ERYTIIROMELALGIA. 
 By 
 
 2. ANGIONEUROTIC (EDEMA. 
 
 By 
 
 3. SCLERODERMA. 
 
 [ 'IS Pa ? es l 
 
 [ tfo Pages] 
 
 [ 1 0 Pages] 
 
 
 fm> 
 
 [ Pages] 
 
 Pages] 
 
 Pages] 
 
 By 
 
 4. FACIAL 11 KM l ATROPHY, OSTEITIS DEFORMANS, HYPER¬ 
 TROPHIC PULMONARY OSTEOARTHROPATHY, LEON¬ 
 TI ASIS OSSEA, MICROMEGALY. ^ ^ c f [ 
 
 By 
 
 Pages] 
 
A SYSTEM OF MODERN MEDICINE.— V O L UME VII. 
 
 15 
 
 VOLUME VII. 
 
 PART I. 
 
 DISEASES OF THE NERVOUS SYSTEM. 
 
 1. GENERAL INTRODUCTION. 
 
 By 
 
 
 2. MEDICAL OPHTHALMOLOGY. 
 
 By 
 
 3. DISEASES OF THE AFFERENT SYSTEM. 
 
 By 
 
 [ T Pages] 
 
 [ VL Pages] 
 
 [ l/u Pages] 
 
 4. DISEASES OF THE EFFERENT SYSTEM. [ Co Pages] 
 
 By 
 
 5. COMBINED DISEASES. [ »C Pages] 
 
 By 
 
 6. DISEASES OF THE MENINGES. [ Pages] 
 
 By 
 
 7. SCLEROSIS. 
 
 By 
 
 [ 1o Pages] 
 
 8. DISEASES OF THE CORD. 
 
 [ Co Pages] 
 
 By 
 

 
 lei A SYSTEM OF MODERN ME DIC INE.—V O L UM E VII. 
 
 9. DISEASES OF THE BRAIN. 
 
 By 
 
 10. DISEASES OF THE NERVES. 
 
 By 
 
 By 
 
 /V ^ C / yy ^ By 
 
 I 
 
 
 By 
 
 14. NEUROSES. 
 
(I. 
 
 m 
 
 , - • 'V'M. ■ • > . i 
 
 - 
 
 M'-u- ( ‘ >.i <■ 
 
 SCHEME 
 
 C 
 
 A S Y STEM OF 
 
 MODEEN MEDICINE. 
 
 / ‘ *£ -jGl (s-' ' - '“j - • 
 
 TO HE EDITED BY 
 
 TO HE PUBLISHED BY 
 
 LEA BROTHERS & COMPANY, 
 
 PHILADELPHIA. 
 
 
-l -hn-^r 
 
 
 N O T E 
 
 This work is planned to appear in seven octavo volumes, 
 averaging 800 pages each, with about 5^0 words to the page. 
 It is essential that articles should deal with their topics as con¬ 
 cisely as possible without sacrifice of completeness . 
 
 Especial attention should be given to the adoption and main¬ 
 tenance of a clear and simple subdivision of material in tlfc 
 manuscript, for which the following order is suggested: Etiology, 
 Special Pathology, Symptoms, Diagnosis, Prognosis, Treat¬ 
 ment and Sequela’. 
 
 Illustrations are desired where necessary for the elucidation 
 of the text and are to be included in the number of pages 
 allotted . They should be allowed for as occupying one-third 
 of a page each upon the average. Text references should be 
 made by footnotes. 
 
 
 
CONTENTS 
 
 OF A 
 
 SYSTEM OF MODERN MEDICINE. 
 
 VOLUME 1 4 iL !< ?° 
 
 PART i. 
 
 THE DEVELOPMENT OF INTERNAL MEDICINE. 
 
 I 
 
 1. GENERAL INTRODUCTION. TIIR^irVTttf^LQ£iX_OI''—L^ECTION 
 l^MfrMT¥r^ TTT\ I ORS , CAN.CEIL-Erc. [ p ag e S ] 
 
 By 
 
 2. HEREDITY AND DISEASE. 
 
 By TC«aVcJ 
 
 [ Pages] 
 
 PART II. 
 
 DISEASES CAUSED BY PHYSICAL AGENTS. - 
 
 1. HEAT AND COLD. 
 
 By 
 
 T<OU vex) — 
 
 [ Pages] 
 
 2. LIGHT. 
 
 By 
 
 Pages] 
 
 3. ELECTRICITY. 
 
 I!y 
 
 f Pages] 
 
2 
 
 T Z 7 
 
 A SYSTEM OF MODERS M E DICIN E .—V O L U M E I. 
 
 4. VARIATIONS IN ATMOSPHERIC PRESSURE. [' Pages] 
 
 By 
 
 5. MOUNTAIN SICKNESS. 
 
 By 
 
 DISEASES CAUSED BY CHEMICAL AGENTS. 
 
 1. LEAD. 
 
 By 
 
 2. ARSENIC. 
 
 'TeeCAl/ob. 
 
 [ Pages] 
 
 [ Pages] 
 
 By 
 
 3. OTHER METALLIC POISONS, MERCURY, PHOSPHORUS, Etc. 
 
 [ Pages! 
 By 
 
 4. CARBON MONOXIDE AND DIOXIDE. 
 By 
 
 [ Page*] 
 
 DISEASES CAUSED BY ORGANIC AGENTS. 
 
 1. ALCOHOL. 
 
 By 
 
 2. OPIUM. 
 
 3. COCAINE, Etc 
 
 Hur^ Tc c£A. r o , 
 
 By 
 
 [ Pages] 
 
 [ Pages] 
 
 L Pages] 
 
 By 
 

 A SYSTEM OF MODERN MEDIC1NE.—VOLUME I. 3 
 
 4. FOODS — MILK, FISH, MEAT, Etc. funry. /UcZ*'Jca j- Pages j 
 
 5. VENOMS. 
 
 By 
 
 By 
 
 'KoGi-cLa'- 
 
 l Pages] 
 
 AUTO INTOXICATIONS NORMAL AND 
 
 A By 
 
 pathological! y . , N 
 
 V Tt 
 
 INTOXICATIONS IN GENERAL. PATHOLOGY. 
 
 By 
 
 DISEASES CAUSED BY VEGETABLE PARASITES. 
 
 1. ASPERGILLUS.'N - TUCXaW* 
 
 By 
 
 Pages 
 
 2. ACTINOMYCES. 
 
 By\ 
 
 [ Pages] 
 
 3. BLASTOMYCETEj 
 By 
 
 [ Pages] 
 
 lYUayud-oc* - Tcczi'jci). 
 
 DISEASES CADSED BY PROTOZOA. Py^^c.. U<OU^- 
 
 I. MALARIA. 
 
 By ^40*^ , T<CC^|Vca> 
 
 2. TRYPANOSOMIASIS. 
 
 By AtWa _ 
 
 3. AMCEBIC DYSENTERY. 
 
 By 
 
 S0\ ^ 
 
 ■ 5 - 
 
 [ Pages] 
 
 r Pages] 
 
 [ Pages] 
 
 DISEASES CAUSED BY ANIMAL PARASITES. 
 
 Bv frr (*. re Pcs ' i// A 
 
4 
 
 ^37 
 
 A SYSTEM OF MODERN M E DICIN E .— V O L V M E I. 
 
 PART III. 
 
 NUTRITION. 
 
 GENERAL CONSIDERATIONS OF METABOLISM, NORMAL AND IN 
 DISEASE. , [ Pages] 
 
 By 6 fu' It (AaA Tc CeVt/cA- 
 
 DISEASES OF NUTRITION. 
 
 ~ TeCH^Oc*. 
 
 4. OBESITY. 
 
 By 
 
 
 5. RICKETS. 
 
 (>. SCURVY. 
 
 Bv ku 
 
 i| iJcL • Jo-. 
 
 By 
 
 [ Pages] 
 
 [ Pages] 
 
 [ Pag«l 
 
 
 [ Pages] 
 
 [ Pages] 
 
 [ Pages] 
 
A SYSTEM OF MODERN M E DIC IN E. -V 0 LIT M E II. 5 
 
 T . n . TT Ati 
 
 \ OL U ME TT« q/i/t*- 
 
 JLi_efc o\^~. _i/(c-0Cfx} _ 'TV ce.\'iJeJ 
 
 INFECTIOUS DISEASES. 
 
 1. TYPHOID AND TYPHUS FEVERS. 
 
 By flA^CiK* 
 
 [ Pages] 
 
 - Ao c/C „ TV ou ci 
 
 2. SMALLPOX, VACCINATION AND VARICELLA. [ Pages] 
 
 By 
 
 - 7 urb ort cxa W<i „ 
 
 6. WHOOPING COUGH. 
 
 v /it 
 
 By 
 
 [ Pages] 
 
 7. INFLUENZA. 
 
 By 
 
 
 T< GnVrf 
 
 f Pages] 
 
 8. DENGUE. 
 
 By 
 
 . rtan'Jet 
 
 [ Pages] 
 
 0. CEREBRO spinal fever. 
 
 by (urftCA . TV an'Job. 
 
 Pages] 
 
 
 ’C'lO. 
 
 'I rCJlAX/iJ. 
 
6 
 
 (i 
 
 
 
 A SYSTEM OF MODERN MEDICINE.— VOL UME II. 
 
 10. PNEUMONIA. 
 
 By YhtcMH - 
 
 rc<u)*7 7UA'c>?&-+f 1'cim^i*, 
 
 , [ Pages] 
 
 h ereJ'x) 
 
 11. SEPTICEMIA. 
 
 By 
 
 PcA<a - r#c«Ai/<^ 
 
 [ Pages] 
 
 12. RHEUMATIC FEVER. 
 
 y r . r«otAV«*>. 
 
 f Pages] 
 
 By 
 
 13. ASIATIC CHOLERA. 4 , . [ Pages] 
 
 „ AukC*-.. rc< -“ 
 
 By 
 
 14. YELLOW FEVER. [ Pages] 
 
 F Pi 
 
 By fkuotf - ^ rc< ^ ? ^ 
 
 nu. 
 
 15. PLAGUE. 
 
 By 
 
 / TtCL\diA 
 
 [ Pages] 
 
 16. EPIDEMIC DYSENTERY. 
 
 By 
 
 r Stu!s^. recAA'Jc*- 
 
 [ Pages] 
 
 
 a 
 
i 
 
 A SYSTEM OF MODERN MEDICINE.—VOLUME Ill. 7 
 
 CaJMiZ fir, Ocfi i & <<{o S' 
 
 VOLUME TTT. ' &a * 
 
 _3 Ti^mi^CC, ( J^-'7 
 
 PART I. 
 
 INFECTIOUS DISEASES—Continued. 
 
 1. MALTA FEVER. 
 
 By 
 
 TectA'tfoS. 
 
 [ P»S«s] 
 
 2. BERI BERI. [ Pages] 
 
 By iC-c.fr jh t hen 
 
 •Cao&j i/u ’ t»a i +? 
 
 3. ANTHRAX. 
 
 [ Pages] 
 
 By n^n-al ^ ?W-£ Tc<*Vt /0 
 
 
 4. HYDROPHOBIA. 
 
 By 
 
 
 [ Pages] 
 
 5. TETANUS. 
 
 By V* . TO «-i ’UtA 
 
 [ Pages] 
 
 (i. GLANDERS. 
 
 By 
 
 tl^JcA- *\ . rect*VtO 
 
 [ Pages] 
 
 7. SYPHILIS. 
 
 By , 
 
 [ Pages] 
 
 8. GONORRHIEAL INFECTION. |- p ages ] 
 
 By - Awf- T<? ccViliO -yeftAiy 
 
 fun. • 
 
 9. TUBERCULOSIS. 
 
 By IWv r 7W t/CuVO 
 *C. 
 
 [ Pages] 
 

 8 A SYSTEM OF MODERN M E DICIN E.—V O LU M E III. 
 
 10. LEPROSY. 
 
 By . TfCOiVci) 
 
 [ Pages] 
 
 11. FEBRICULA, WEIL’S DISEASE, Etc. 
 
 [ Pages] 
 
 
 By 
 
 in \ - 
 
 ( - ' Pte’JoM'cx* <ff h\fic A 
 
 
 *4-04 <£/. 
 
 Op? 
 
 PART II. 
 
 DISEASES OF THE RESPIRATORY TRACT. 
 
 1. PHYSICS OF RESPIRATION. 
 
 By / */^TV7{A-% 
 
 3. aFTHE^o^E. 
 
 Zplih^ By V\cJL<LA*> - ftZZA'jcD- 
 
 By 
 
 5. DISEASES OF THE LARYNX. 
 
 By 
 
 By 
 
 By 
 
 
 a 
 
 Pages] 
 
 2. PHYSICAL SIGNS OF DISEASES OF RESPIRATORY TRACT [ Pages 
 By •' 
 
 I 
 
 Pages] 
 
 [ Pages] 
 
 [ Pages] 
 
 6. DISEASES OF THE BRONCHI. [ Pages] 
 
 7. DISEASES OF THE LUNGS. Jf^u. M* -TtCc^VcO „ [ p age s] 
 
 

 A SYSTEM OF MODERN M E DICIN E .— V 0 L U M E IV. t) 
 
 8. DISEASES OF THE PLEURA. [ Pages] 
 
 By *** nCei'tXJ 
 
 9. DISEASES OF THE MEDIASTINUM. [ p age s] 
 
 By &fu 
 
 VOLIJME IV. 
 
 PART I. 
 
 faJ&tkd fvr > 0 <?* f ' ifos~ 
 
 DISEASES OF THE CIRCULATORY SYSTEM. 
 
 1. THE PHYSICS OF VASCULAR DISEASE, MECHANICAL 
 
 STRAIN, Etc. [ Pages] 
 
 By JfocVt^ 
 
 2. DISEASES OF THE PERICARDIUM. 
 
 By 'T'U Ytf- 
 
 Pages] 
 
 3. ENDOCARDITIS, VALVULAR DISEASE, HYPERTROPHY AND 
 
 DILATATION. [ Pages] 
 
 By TfUlAfo. 
 
 4. DISEASES OF THE MYOCARDIUM AND CARDIAC NEUROSES. [ Pages] 
 
 By (hUk+eSs 
 
 5. CONGENITAL CARDIAC DISEASE. [ i» ages | 
 
 By L t -&frlr'{k 
 
 (i. DISEASES OF THE ARTERIES AND ANEURISM. 
 By 
 
 Pages] 
 
10 
 
 
 A SYSTEM OF MODERN MEDICINE.—VOLUME V. 
 
 7. THROMBOSIS, EMBOLISM AND PHLEBITIS. 
 By &lo(0 
 
 [ Pages] 
 
 8. DISEASES OF THE LYMPHATICS, f 
 
 * By (*)A^llZoC. 
 
 [ Pages] 
 
 PART II. 
 
 DISEASES OF THE BLOOD. 
 
 V 1. GENERAL PATHOLOGY OF THE BLOODFORMING ORGANS. [ Pages] 
 
 v 2. AN.EMIA, CHLOROSIS, PERNICIOUS AND SECONDARY AN.EMIA 
 
 AND LEUKEMIA. [ Pages] 
 
 By 
 
 3. PURPURA AND H.EMOPHILIA. 
 
 By PrtJf 
 
 [ Pages] 
 
 ijuuicx ^ SfociUtA* U&i-J /u, __ 
 
 VOLUME V. c ‘ im> (” 
 
 V>i> Jcuf-C' 'tyf 
 
 DISEASES OF THE ALIMENTARY TRACT. 
 
 1. PATHOLOGY OF SECRETION AND DIGESTION. 
 
 By St*c£/cC, - 
 
 2. DISEASES OF THE MOUTH. 
 
 By 
 
 3. DISEASES OF THE SALIVARY GLANDS. 
 
 By 
 
 [ Pages] 
 
 [ Pages] 
 
 [ Pages] 
 
BALTIMORE, 
 
 DR. THOMAS MCCRAE, 
 807 St. Paul Street. 
 
 CONSULTATION HOURS, 
 
 3-5 P. M. 
 
 k fyuuh liJCt %>voy\^liA. 
 
 1. '^ i uJ—cfu\ t/> ’CiA~t 
 
 ^ J Ukj} ial t?u_ iaaXl w (/yJi $t-hjuui-Ajy 
 
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1 
 
 
 
 I 
 
BALTIMORE, 
 
 1 
 
 DR. THOMAS MCCRAE, 
 807 St. Paul Street. 
 
 CONSULTATION HOURS, 
 
 3-6 P. M. 
 
 u 
 
 37 'O') 
 
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11 
 
 KJ 
 
 A SYSTEM OF MODERN MEI)TCINE. — VOL UME V. 
 
 4. DISEASES OF THE PHARYNX AND TONSILS. [ Pages] 
 
 By Pa cXam) 
 
 5. DISEASES OF THE (ESOPHAGUS. [ P»g t:s 0 
 
 By X fa C 
 
 (i. DISEASES OF THE STOMACH. — (^Ama'c. %\axiu! [ Pages] 
 
 j~l4A. cfca^C. ? Vi 
 
 7. DISEASES OF THE INTESTINES, t, [ Pages] 
 
 Rv 
 
 8. DISEASES OF THE LIVER. 
 
 By 
 
 Pages] 
 
 9. DISEASES OF THE PANCREAS. 
 By 
 
 Pages] 
 
 10. DISEASES OF THE PERITONEUM. [ Pages] 
 
 By 
 
 11. ENTEROPTOSIS. 
 
 Psrxn^x^ , 
 
 Pages] 
 
 By 
 
12 
 
 TZ7 
 
 A SYSTEM OF MODERN MEDICINE.— VOLUME VI. 
 
 VOLUME VI. 
 
 PART J, 
 
 DISEASES OF THE KIDNEY. 
 
 1. MALFORMATIONS, Etc. 
 
 By 
 
 [ Pages] 
 
 2. CIRCULATORY DISTURBANCES. 
 
 W*- Bv 
 
 3. ANOMALIES OF SECRETION. 
 
 By 
 
 4. UR.EMIA. 
 
 [ Pages] 
 
 Pages] 
 
 [ Pages] 
 
 By 
 
 5. ACUTE NEPHRITIS. 
 
 By 
 
 6. CHRONIC NEPHRITIS. 
 By 
 
 [ Pages] 
 
 [ Pages] 
 
 \^_7. AMYLOID. 
 
 By 
 
 Pages] 
 
 ij 8. PY 
 
 PYELITIS. 
 
 V' 
 
 By 
 
 
 V 
 
 9. HYDRONEPHROSIS. 
 
 By 
 
 Pages] 
 
 f Pages] 
 
13 
 
 m 
 
 A SYSTEM OF MODERN MEDICINE—VOLUME VI. 
 
 10. STONE IN KIDNEY. [ Pages] 
 
 By 
 
 11. TUMORS, CYSTS. 
 
 By 
 
 [ Pages] 
 
 12. ABSCESS. 
 
 [ P^es] 
 
 By 
 
 
 TART II. 
 
 DISEASES ASSOCIATED WITH INTERNAL SECRETION. 
 
 By 
 
 tied 
 
 4. LYMPHATICS. 
 
 5. MYXCEDEMA. 
 
 6. CRETINISM. 
 
 By 
 
 By 
 
 By 
 
 By 
 
 By 
 
 7. ACROMEGALY. 
 
 By 
 
 [ Pages] 
 
 [ Pages] 
 
 [ Pages] 
 
 [ Pages] 
 
 Pages] 
 
 [ Pages] 
 
 Pages] 
 
14 
 
 
 A SYSTEM OF MODERN MED101NE.—VOLUME VI. 
 
 PART III. 
 
 DISEASES OF OBSCURE CAUSATION. 
 
 1. HODGKIN’S DISEASE. 
 
 By 
 
 
 [ Pages] 
 
 2. ARTHRITIS DEFORMANS. 
 
 By 
 
 7.^' 
 
 c P 
 
 
 [ Pages] 
 
 3. OSTEOMALACIA. 
 
 By 
 
 [ Pages] 
 
 PART IV. 
 
 DISEASES OF THE MUSCLES. 
 
 By %))CAA*% c-i % 
 
 VASOMOTOR AND TROPHIC DISORDERS. (Mk*.. 
 
 1. RAYNAUD'S DISEASE AND ERYTHROMELALGIA. 
 By 
 
 Pages] 
 
 2. ANGIONEUROTIC (EDEMA 
 By 
 
 [ Pages] 
 
 3. SCLERODERMA. 
 
 By 
 
 t Pages] 
 
 4. FACIAL HEMIATROPHY, OSTEITIS DEFORMANS, HYPER¬ 
 TROPHIC PULMONARY OSTEO-ARTHROPATHY, LEON- 
 TIASIS OSSEA, MICROMEGALY. ^ [ Pages] 
 
 By 
 
 
 0 4 — 
 
 
 UjC^ 
 
A SYSTEM OF MODERN M E D 1C IN E.-V 0 LU M E VII. 
 
 15 
 
 VOLUME VII. 
 
 PART I. 
 
 DISEASES OF THE NERVOUS SYSTEM. 
 
 1. GENERAL INTRODUCTION. [ Pages] 
 
 By 
 
 2. MEDICAL OPHTHALMOLOGY. [ Pages] 
 
 By 
 
 3. DISEASES OF THE AFFERENT SYSTEM. [ Pages] 
 
 By 
 
 4. DISEASES OF THE EFFERENT SYSTEM. [ Pages] 
 
 By 
 
 5. COMBINED DISEASES. [ Pages] 
 
 By 
 
 6. DISEASES OF THE MENINGES. [ Pages] 
 
 By 
 
 7. SCLEROSIS. [ Pages] 
 
 By 
 
 8. DISEASES OF THE CORD. 
 
 [ Pages] 
 
It) 
 
 A SYSTEM OF MODERN M E DIC INE.—V 0 L U M E VII. 
 
 9. DISEASES OF THE BRAIN. [ Pages] 
 
 By 
 
 10. DISEASES OF THE NERVES. [ Pages] 
 
 By 
 
 11. GENERAL FUNCTIONAL DISORDERS. [ Pages] 
 
 By 
 
 12. HYSTERIA. [ p a a es ] 
 
 By 
 
 13. NEURASTHENIA. [ Pages] 
 
 By 
 
 14. NEUROSES. [ Pages] 
 
 By 
 
 PART II. 
 
 MENTAL DISEASES. 
 
r o 
 
 OSLERS SYSTEM OF MEDICINE 
 
 CHAPTER 
 
 t XIV — Toxaemia, Septicaemia and Pyaemia. 
 
 By Richard M. Pearce, M.D., Professor of Pathology 
 and Bacteriology in the Medical College, Albany, N.Y. 
 
 XV — Rheumatic Fever. 
 
 By Frederick J. Poynton, M.D., F.R.C.P. (Lond.), 
 Assistant Physician to the University College Hos¬ 
 pital and to the Hospital for Sick Children, Great 
 Ormond St., London ; Formerly Sub-Dean of the 
 Medical Faculty of the University College, London. 
 
 CHAPTER 
 
 XXVII—Yellow Fever. 
 
 By James Carroll, M.D, Professor of Bacteriology 
 and Clinical Microscopy in the Army Medical School, 
 Washington, D.C.; Professor of Bacteriology and 
 Pathology in the George Washington University, 
 Medical Department, Washington, D.C. 
 
 XXVIII—Plague. 
 
 By W. J. Calvert, M.D., Assistant Professor of Inter¬ 
 nal Medicine, University of Missouri, Columbia, Mo. 
 
 XXVI—Asiatic Cholera. 
 
 By W. P. Dunbar, M.D., Director, Hygienic Institute, 
 Hamburg. 
 
 XXIX—Epidemic Dyscntery. 
 
 By K. Siiiga, M.D., University of Tokio. 
 
 VOLUME III 
 
 Part I — Infectious Diseases — Continued 
 
 I — Malta Fever. 
 
 By David Bruce, C.B., F.R.S., D.Sc., Colonel, 
 R.A.M.C. 
 
 II — Beri-Beri. 
 
 By Maximilian Herzog, M.D., Manila, P.I. 
 
 VIII—The Pathology of Tuberculosis. 
 
 By W. G. MacCallum, M.D., Associate Professor of 
 Pathology, Johns Hopkins Medical School and Hos¬ 
 pital, Baltimore. 
 
 IX — The Symptoms of Tuberculosis. 
 
 III — Anthrax. Hydrophobia. Glanders. 
 
 By Mazyck P. Ravenel, M.D., Philadelphia. 
 
 IV — Tetanus. 
 
 By James M. Anders, M.D., Professor of the Theory 
 and Practice of Medicine and Clinical Medicine in 
 the Medico-Chirurgical College, Philadelphia. 
 
 V — Syphilis. 
 
 By William Osler, M.D., Regius Professor of Medi¬ 
 cine in the University of Oxford. 
 
 X—The Diagnosis and Prognosis of Tuber¬ 
 culosis. 
 
 XI—The Treatment of Tuberculosis. 
 
 By Dawrason Brown, M.D., Adirondack Cottage 
 Sanitarium, Saranac Lake, N. Y. 
 
 XII — Leprosy. 
 
 By Isadore Dyer, M.D., Professor of Diseases of the 
 Skin in the Tulane University, Medical Department, 
 New Orleans. 
 
 VI—Gonorrhoeal Infection. 
 
 By Rufus I. Cole, M.D., Associate in Medicine in the 
 Johns Hopkins University and Hospital, Baltimore. 
 
 VII — Tuberculosis. History and Etiology. 
 
 By Edward R. Baldwin, M.D., Saranac Laboratory for 
 the Study of Tuberculosis. 
 
 XIII — Febricula, Weils Disease, etc. 
 
 By Thomas R. Boggs, M.D., Associate in Medicine in 
 the Johns Hopkins University, Baltimore. 
 
 XIV — The Prevention of Infectious Diseases. 
 
 By John S. Billings, Jr., M.D., Department of Public 
 Health, New York City. 
 
 Part II— Diseases of 
 
 XV—The Physics of Respiration. 
 
 XVI—The Physical Signs of Diseases of the 
 Respiratory Tract. 
 
 By Thomas R. Brown, M.D., Associate in Medicine in 
 the Johns Hopkins Medical School and Hospital. 
 
 XVII—Hay Fever. 
 
 By W. P. Dunbar, M.D., Director of Hygienic Institute, 
 Hamburg. 
 
 the Respiratory Tract 
 
 XVIII — Epistaxis. 
 
 By Francis R. Packard, M.D., Professor of Diseases 
 of the Nose and Throat in the Philadelphia Poly¬ 
 clinic. 
 
 XIX Diseases of the Larynx. 
 
 By IT. S. Birkett, M.D., Professor of Laryngology and 
 Otology in McGill University Medical Faculty, 
 Montreal. 
 
 THE OXFORD MEDICAL PUBLICATIONS 
 

 OSLER’S SYSTEM OF MEDICINE) 
 
 JCJC^Diseases of the Bronchi. 
 
 ^ CPHEDRAN 1 M.D., Professor of Medicine and 
 ot Clinical Medicine in the University of Toronto 
 1 oronto. 
 
 XXI Diseases of the Lungs. 
 
 By H. A. Hare, M.D., Professor of Therapeutics and 
 Materia Medica in the Jefferson Medical College 
 Philadelphia. ' 
 
 XXII—Diseases of the Pleura. 
 
 By Walter B. James, M.D., Professor of the Practice of 
 Medicine in the College ol Physicians and Surgeons 
 (Columbia University), New York, and FrederickT. 
 Lord, M.D., Assistant in Clinical Medicine in the 
 Medical School of Harvard University, Boston. 
 
 XXIII—Diseases of the Mediastinum. 
 
 By Henry A. Christian, M.D., Instructor in the Theory j 
 and Practice of Physic in Harvard University, Boston. 
 
 VOLUME IV 
 
 Part I—Diseases of the Circulatory System 
 
 I — The Physics of Vascular Disease, Meehan- 
 ical Strains, etc. 
 
 By Charles F. Hoover, M.D., Professor of Physical 
 Diagnosis in the Medical College of the Western 
 Reserve University, Cleveland. 
 
 II—Diseases of the Pericardium. 
 
 By A. McPhedran, M.D., Professor of Medicine and of 
 Clinical Medicine in the Univ. of Toronto, Toronto. 
 
 HI—Endocarditis, Valvular Disease, Hyper¬ 
 trophy, Dilatation. 
 
 By William S. Thayer, M.D., Professor of Clinical 
 M edicine in the Johns Hopkins University, Baltimore. 
 
 IV—Diseases of the Myocardium. 
 
 By Robert H. Babcock, A.M., M.D., Former Professor of 
 Clinical Medicine and Diseases of the Chest, College 
 of Physicians and Surgeons, Chicago. 
 
 V — Cardiac Neuroses. 
 
 By Charles F. Hoover, M.D., Professor of Physical 
 Diagnosis in the Medical College of the Western Re¬ 
 serve University, Cleveland. 
 
 VI — Congenital Cardiac Disease. 
 
 By Maude E. Abbott, B.A., M.D., Governors' Fellowin 
 Pathology in McGill University, Montreal. 
 
 VII — Diseases of the Arteries and Aneurism. 
 
 By William Osler, M.D., Regius Professor of Medi¬ 
 cine in the University of Oxford. 
 
 VIII — Thrombosis, Embolism, Phlebitis. 
 
 By George Blumer, M.D., Prof, of Theory and Prac- ] 
 tice of Medicine in Yale Medical School, New Haven. 
 
 IX—Diseases of the Lymphatics. 
 
 By A. S. Warthin, M.D., Ph.D., Professor of Pathology 
 in the University of Michigan, Department of Medi¬ 
 cine, Ann Arbor. 
 
 X—The General Pathology of the Blood- 
 forming Organs. 
 
 Part II—Diseases of the Blood 
 
 XI — Ancemia. Chlorosis. Pernicious and 
 
 Secondary Ancemia. Leukcemia. 
 
 By Richard C. Cabot, M.D., Instructor in Clinical 
 Medicine in the Medical School of Harvard Univer¬ 
 sity, Boston. 
 
 XII—Purpura and Haemophilia. 
 
 By Joseph H. Pratt, M.D., Asst, in Theory and Practice 
 of Physic in the Med. School of Harvard Univ., Boston. 
 
 XIII—Diseases of the Spleen. 
 
 By Charles G. Stockton, M.D., Prof, of the Principles 
 and Practice of Medicine and Clinical Medicine in 
 Med. Department, Univ. of Buffalo, and Irving P. 
 Lyon, M.D., Instructor in Clinical Medicine, Medical 
 Department, University of Buffalo, Buffalo. 
 
 VOLUME V 
 
 I—The Pathology of Secretion and Digestion. 
 
 Diseases of the Alimentary Tract 
 
 By Charles G. Stockton, M.D., Professor of the Prin¬ 
 ciples and Practice of Medicine and Clinical Medicine 
 in the Medical Department of the University of 
 Buffalo, Buffalo. 
 
 II—Diseases of the Mouth. 
 
 Ill—Diseases of the Salivary Glands. 
 
 By David Riesman, M.D., Associate in Medicine in the 
 Medical Department of the University of Pennsyl¬ 
 vania ; Professor of Clinical Medicine in the Phila¬ 
 
 delphia Polyclinic, Philadelphia. 
 
 THE OXFORD MEDICAL PUBLICATIONS 
 
u 
 
 
 NOSLER’S SYSTEM OF MEDICINE 
 
 CHAPTER 
 
 TV-—Diseases of the Pharynx and Tonsils. 
 
 r . By Francis R. Packard, M.D., Professor of Diseases of 
 the Nose and Throat in the Philadelphia Polyclinic. 
 
 V — Diseases of the CEsophagus. 
 
 By John McCrak, M.D. ( Tor .), M.R.C.P, (Lond.), 
 Lecturer in Pathology in McGill University, Montreal. 
 
 1 VI —Organic Diseases of the Stomach. 
 
 By C. F. Martin, M.D., Assistant Professor of Medicine 
 and Clinical Medicine in McGill University Faculty 
 of Medicine, Montreal. 
 
 VII—Functional Diseases of the Stomach. 
 
 By Julius Friedenwald, M.D., Professor of Diseases 
 of the Stomach in the College of Physicians and 
 Surgeons, Baltimore. 
 
 TII-—Diseases of the Intestines. 
 
 By Alfred Stengel, M.D., Professor of Clinical Medicine 
 in the Medical Department of the University of Penn¬ 
 sylvania, Philadelphia. 
 
 CHAPTER 
 
 IX—Diseases of the Liver. 
 
 By A. 0. J. Kelly, M.D., Assistant Professor of Medicine 
 in the Medical Department of the University of Penn¬ 
 sylvania, Professor of the Theory and Practice of Med¬ 
 icine in the University of Vermont. 
 
 X—Diseases of the Pancreas. 
 
 By Eugene L. Opie, M.D., Associate in the Rockefeller 
 Institute for Medical Research, New York. 
 
 XI — Diseases of the Peritoneum. 
 
 By H. D. Rolleston, M.D., F.R.C.P., Physician to St. 
 George’s Hospital, and P. W. Sargent, M.B., B.C. 
 (Cantab.), F.R.C.S., St. Thomas’ Hospital, London. 
 
 XII — Enteroptosis. 
 
 By Thomas R. Brown, M.D., Associate in Medicine in 
 the Johns Hopkins University School and Hospital, 
 Baltimore. 
 
 VOLUME VI 
 
 Part I — Diseases of the Kidneys 
 
 I — Malformation of the Kidneys. 
 
 II — Circulatory Disturbances of the Kidneys. 
 
 Ill—Anomalies of Secretion. 
 
 IV Urcemia. 
 
 By A. E. Garrod, M .D., F.R.C.P. (Lond.), Assistant 
 Physicianto St. Bartholomew’s Hospital, London. 
 
 V — Acute Nephritis. 
 
 VI — Chronic Nephritis. 
 
 VII — Amyloid Nephritis. 
 
 By James B. Herrick, M.D., Professor of Medicine in 
 the Rush Medical College, Chicago. 
 
 VIII— Pyelitis. 
 
 IX — Hydronephrosis. 
 
 X — Stone in the Kidney. 
 
 XI—Tumors and Cysts of the Kidneys.. 
 
 XII — Abscess of the Kidneys. 
 
 Hugh H. Young, M.D., Associate Professor of Genito¬ 
 urinary Surgery in the Johns Hopkins Medical School 
 and Hospital, Baltimore. 
 
 XIII — Renal Infections. 
 
 By Thomas R. Brown, M.D., Associate in Medicine in 
 the Johns Hopkins Medical School and Hospital, 
 Baltimore. 
 
 Part II — Diseases Associated with Internal Secretion 
 
 AIV—Diseases of the Suprarenal Glands. 
 
 XV Diseases of the Thyroid Glands. 
 
 A VI — Myxcedema. 
 
 A VII — Cretinism. 
 
 Part III — Diseases of Obscure Causation 
 
 XIX — Hodgkin's Disease. 
 
 By W. T. Longcope, M.D., Director of the Ayer Laboratory of the Pennsylvania Hospital, Philadelphia. 
 
 XX— Arthritis Deformans. 
 
 By Thomas McCrae, M.D., F.R.C.P. (Lond.), Associate Professor of Medicine and Clinical Therapeutics in the Johns Hopkins 
 University, Baltimore. 
 
 XVIII — Acromegaly. 
 
 By George Dock, M.D., Professor of the Theory and Prac¬ 
 tice of Medicine and Clinical Medicine in the University 
 of Michigan, Department of Medicine, Ann Arbor. 
 
 XXI Osteomalacia. 
 
 By George Dock, M.D., Professor of the Theory and Practice of Medicine and Clinical Medicine in the University of 
 Michigan, Department of Medicine, Ann Arbor. 
 
 THE OXFORD MEDICAL PUBLICATIONS 
 
OSLER’S SYSTEM OF MEDICINE 
 
 CHAPTER Part IV—Diseases of the Muscles 
 
 XXII — Myositis. 
 
 By Walter R. Steiner, M.D., Pathologist and Bacteriologist to the Hartford Hospital, Hartford, Conn. 
 
 XXIII Myotonia, Paramyoclonus Multiplex, Myasthenia Gravis. 
 
 By Daniel J. McCarthy M.D., Prof, of Medical Jurisprudence in the Medical Dept., Univ. of Pennsylvania, Philadelphia. 
 
 Part V — Vasomotor and Trophic Disorders 
 
 XXIV — Raynaud’s Disease and 
 
 Erythromelalgia. 
 
 XXV — Angioneurotic (Edema. 
 
 XXVI — Scleroderma. 
 
 By William Osler, M.D., Regius Professor of Medi¬ 
 cine in the University of Oxford. 
 
 De- 
 
 XXVII—Facial Hemiatrophy, Osteitis 
 formans, Micromegaly, etc. 
 
 By Charles P. Emerson, M.D., Associate in Medicine 
 in the Johns Hopkins University, Baltimore. 
 
 XXVIII—Medical Features of Life Insurance. 
 
 By Charles Lyman Greene, Professor of Medicine in 
 the University of Minnesota, St. Paul. 
 
 VOLUME VII 
 
 Diseases of the Nervous System 
 
 I—General Introduction. 
 
 By Lewellys F. Barker, M.D., Professor of Medicine 
 in the Johns Hopkins University, Baltimore. 
 
 II—Diseases of the Motor Tract. 
 
 By William G. Spiller, M.D., Professor of Neuro¬ 
 pathology and Associate Professor of Neurology in 
 the University of Pennsylvania, Philadelphia. 
 
 III — Combined System Diseases. 
 
 By David A. Shirres, M.D., Lecturer on Neuropatho¬ 
 logy in McGill University, Montreal. 
 
 IV — Diseases of the Meninges. Diseases of 
 
 the Brain. 
 
 By Edwin Bramwell, M.B., M.R.C.P. (Lond.), F.R.S. 
 (Edin.), F.R.C.P. (Edin.), University Tutor in Clinical 
 Medicine in the Royal Infirmary, Edinburgh. 
 
 V—Diseases of the Spinal Cord. 
 
 By E. Farquhar Buzzard, M.D., F.R.C.P. (Lond.), 
 Assistant Physician to the National Hospital for the 
 Paralysed and Epileptic, London. 
 
 VI—Compression of the Spinal Cord. Tumors 
 of the Spinal Cord. 
 
 By Harvey Cushing, M.D., Associate Professor of Sur¬ 
 gery in the Johns Hopkins University, Baltimore. 
 
 VII—Diffuse and Focal Diseases of the 
 Brain. Topical Diagnosis, Aphasia. 
 
 By Joseph Collins, M.D., Professor of Neurology in 
 the Post-Graduate Medical School, New York. 
 
 VIII—Affections of the Blood Vessels. 
 
 By Henry M. Thomas, A.M.,iM.D., Clinical Professor of 
 Neurology in the Johns Hopkins Univ., Baltimore. 
 
 IX—Tumors. Hydrocephalus. 
 
 By Harvey Cushing, M.D., Associate Professor of Sur¬ 
 gery in the Johns Hopkins University, Baltimore. 
 
 X — Encephalitis. Abscess. 
 
 By E. E. Southard, M.D., Boston. 
 
 XI—Diseases of the Peripheral Nerves. 
 Neuritis. Neuromata. Diseases of 
 the Spinal Nerves. 
 
 By Gordon M. Holmes, M.D, Director of the Nervous 
 Disease Research Fund, National Hospital for the 
 Paralysed and Epileptic, London. 
 
 XII—Diseases of the Cerebral Nerves. 
 
 By Edward W. Taylor, M.D., Instructor in Neurology 
 in the Medical School of Harvard University, Boston. 
 
 XIII — Syphilis and Parasyphilitic Affections 
 of the Nervous System. Hemiplegia 
 and Diplegia in Children. Amaurotic 
 Family Idiocy. 
 
 By Bernard Sachs, M.D., Alienist and Neurologist to 
 Bellevue Hospital; Neurologist to Mt. Sinai Hospital, 
 New York. 
 
 XIV — General and Functional Diseases. Para¬ 
 lysis Agitans. Chorea. Choreiform 
 Affections. Infantile Convulsions. 
 
 By Daniel J. McCarthy, M.D., Professor of Medical 
 Jurisprudence, Univ. of Pennsylvania, Philadelphia. 
 
 XV — Epilepsy. 
 
 By William P. Spratling M.D., Medical Superinten¬ 
 dent of the Craig Colony for Epileptics, Sonyea, N.Y. 
 
 XVI — Migraine. Neuralgia. Professional 
 
 Spasms. Occupation Neuroses. Tetany . 
 Hysteria. 
 
 By Smith Ely Jelliffe, A.M., M.D., Ph.D., Clinical 
 Assistant in the Department of Neurology, Columbia 
 University, New York. 
 
 XVII — Neurasthenia. Traumatic Neuroses. 
 
 By Charles W. Burr, M.D., Professor of Mental 
 Diseases in the Univ. of Pennsylvania, Philadelphia. 
 
 XVIII—Mental Diseases. 
 
 By Clarence B. Farrar, M.D., Instructor in Psychiatry 
 in the Johns Hopkins University, Baltimore. 
 
 THE OXFORD MEDICAL PUBLICATIONS 
 
 henry FROWDE, Oxford University Press. HODDER & STOUGHTON, 20 Warwick Sq., E.C. 
 
■ 
 
 The Oxford Medical Publications 
 
 A SYSTEM OF 
 MEDICINE 
 
 By Eminent Authorities in Great Britain, the United 
 States and the Continent 
 
 EDITED BY 
 
 William Osler 
 
 M.D., F.R.S. 
 
 Regius Professor of Medicine in the University of Oxford; Honorary Professor of Medicine in the Johns 
 Hopkins University, Baltimore; formerly Professor in the University of Pennsylvania, 
 Philadelphia ; and in McGill University, Montreal. 
 
 AND 
 
 Thomas M c Crae 
 
 M.D., F.R.C.P. (Lond.) 
 
 Associate Professor of Medicine, Johns Hopkins University, Baltimore. 
 
 In Seven Octavo volumes of about 900 pages each. 
 Illustrated, price per volume, cloth 24 /= net 
 
 HENRY FROWDE 
 
 Oxford university Press 
 
 LONDON: 
 
 HODDER & STOUGHTON 
 
 20 Warwick Square, E.C. 
 
Osiers System of dTHCedicine 
 
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 rfo/T'EDICINE has become cosmopolitan. Modern means of com- 
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 practice in all parts of the world will be covered. 
 
 Professor Osier’s “System of Medicine ’’ is undoubtedly one of the 
 most important works ever undertaken in the literature of medicine. With 
 well recognised qualifications the Editors unite a wide literary knowledge and 
 an acquaintance with the thinkers and miters of the present day. They have 
 thus been able to collect an exceptional group of contributors who have dealt 
 with the subject assigned to them in a manner specially suited to the needs of 
 the Practitioner. 
 
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 Osier's System of Medicine, 
 published in seven volumes, 
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OSLER’S SYSTEM OF MEDICINE 
 
 VOLUME I 
 
 Introduction History and Forecast of Medicim. 
 
 By William Osler, M.D., Regius Professor of Medicim in the University of Oxford. 
 
 ^CHAPTER Part I — Predisposition and Immunity 
 
 m I—Inheritance and Disease. 
 
 By J. George Adami, M.D., F.R.S., Professor of Pathology in McGill University, Montreal. 
 
 Part II — Diseases caused by Physical Agents 
 
 77— Light. X-Rays. Electricity. Ill—Air. IV—Heat and Cold. 
 
 By Alfred Gordon, M.D., Associate in Mental and Sfervous Diseases in the Jefferson Medical College, Philadelphia. 
 
 Part III — Diseases Caused by Chemical Agents 
 
 , ^ Chronic Lead Poisoning. VIII Poisoning from Carbon Monoxide, Illu- 
 
 VI—Chronic Arsenic Poisoning. minuting - Gas, Combustion Products, 
 
 VII—Other Metallic Poisons, etc. Carbon Bisulphide. 
 
 David L. Edsall, M.D., Assistant Professor of Medicire, University of Pennsylvania, Medical Department, Philadelphia. 
 
 Part IV — Diseases Caused by Organic Agents 
 
 IX — Alcohol. 
 
 X — Opium, Morphinism, Cocaine. 
 
 By Alexander Lambert, M.D., Professor of Clinicd 
 Medicine, Cornell University Medical College, Nev 
 York. 
 
 XI -Foods, Milk, Fish, Meat, etc. 
 
 By Frederick G. Novy, M.D., Professor of Bacterio- 
 ogy in the University of Michigan, Ann Arbor. 
 
 XII — Snake Venoms. 
 
 By Dr. Hideyo Noguchi, Assistant of the Rockefeller 
 Institute' for Medical Research, New York. 
 
 XIII — A uto-Intoxications. 
 
 XIV — Intoxications — Protein, Purin, Carbo¬ 
 
 hydrate and Fat Metabolism. 
 
 By Alonzo Engelbert Taylor, M.D., Prof, of Patho¬ 
 logy, Univ. of California, Med. Dep., San Francisco. 
 
 Part V — Diseases Caused by Vegetable Parasites 
 
 XV—Actinomyces. | XVI—Aspergillus. 
 
 By James Homer Wrigfit, M.D., Assistant Professor ol Pathology in the Medical School of Harvard University, Boston. 
 
 Part VI — Diseases 
 
 XVII — Protozoa. 
 
 By Gary N. Calkins, Ph.D., Professor of Protozoology 
 in the Columbia University, New Y r ork City. 
 
 X VIII—Mosq u i toes. 
 
 By L. O. Howard, Ph.D., Chief, Bureau of Entomology 
 of the United States Department of Agriculture. 
 
 XIX—The Malarial Fevers. 
 
 By Charles F. Craig, M.D., First Lieutenant ami 
 Assistant Surgeon in the United States Army. 
 
 Caused by Protozoa 
 
 XX — Black-water Fever. 
 
 By J. W. W. Stephens, M.D., Walter Myers Lecturer 
 on Tropical Medicine in the University of Liverpool. 
 
 XXI — Trypanosom iasis. 
 
 By David Bruce, C.B., F.R.S., D.Sc., Colonel, 
 R.A.M.C. 
 
 XXII — Amoebic Dysentery. 
 
 By Richard P. Strong, M.D., Director of the Bio¬ 
 logical Laboratory, Manila, P.I. 
 
 Part VII 
 
 XXIII — General Discussion 
 XXIV—Tetramode or Fluke Infection. 
 
 XXV — Tceniasis — Cestode Infection. 
 
 XXVI Pound - Worm Injection — Nemathelm 
 inthes. 
 
 Diseases Caused by Animal Parasites 
 
 XXVII — Leeches. Acariasis. Tongue Worm 
 Infections. Myriapoda. Etc. 
 
 By CharlesW'ardell Stiles, Ph.D.,D.Sc m Chief of the 
 Division of Zoology in the Hygienic Laboratory, 
 United States Public Health and Marine Hospital 
 Service, Washington, D.C. 
 
 THE OXFORD MEDICAL PUBLICATIONS 
 
U 1 
 
 OSLER’S SYSTEM OF MEDICINE 
 
 chapter Part VIII — Nutrition 
 
 XXVIII General Considerations of Metabolism, Normal and in Disease. 
 
 By Russell H. Chittenden, Ph.D., LL.D., Professor of Physiological Chemistry in the Sheffield Scientific School of 
 * ^ v ? r , sity .' N ? vv Haven > Conn., and Lafayette B. Mendel, Ph.D., Professor of Physiological Chemistry in 
 the Sheffield Scientific School, Yale University. 
 
 Part IX — Constitutional Diseases 
 
 XXIX—Diabetes Mellitus. 
 
 XXX—Diabetes Insipidus. 
 
 XXXI—Gout. 
 
 By Thomas B. Futcher, M.B., Associate Professor of 
 Medicine, Johns Hopkins University, Baltimore. 
 
 XXXII—Obesity. 
 
 By James M. Anders, M.D., Professor of Theory and 
 Practice of Medicine and Clinical Medicine in the 
 Medico-Chirurgical College, Philadelphia. 
 
 XXXIII—Rickets. 
 
 By George Frederic Still, M.A., M.D. (Cantab.), 
 F.R.C.P. (Lond.), Professor of Diseases of Children i 
 in King’s College, London. 
 
 XXXIV—Scurvy. 
 
 By Robert Hutchison, M.D., F.R.C.P. (Lond.), Assist- I 
 ant Physician to the London Hospital and to the 
 Hospital for Sick Children, Great Ormond Street, 
 London. 
 
 VOLUME II 
 
 Infectious 
 
 Diseases 
 
 /— Introduction. 
 
 By Ludvig Hektoen, M.D., Professor of Pathology in 
 the University of Chicago and the Rush Medical 
 College, Chicago. 
 
 II—Typhoid Fever. History and Etiology. 
 
 III — Pathology of Typhoid Fever. 
 
 IV — The Symptoms of Typhoid Fever. 
 
 V—The Diagnosis and Prognosis of Typhoid 
 Fever. 
 
 VI— The Prophylaxis and Treatment of 
 
 Typhoid Fever. 
 
 VII — Typhus Fever. 
 
 VIII—Relapsing Fever. 
 
 By Thomas McCrae, M.D., M.R.C.P. (Lond.), Associ¬ 
 ate Professor of Medicine and Clinical Therapeutics 
 in the Johns Hopkins University, Baltimore. 
 
 IX — Smallpox. 
 
 By William T. Councilman, M.D., Professor of Patho¬ 
 logy in the Medical School of Harvard Univ., Boston. 
 
 X — Vaccination. 
 
 By George Dock, M.D., Professor of Theory and Prac¬ 
 tice of Medicine and Clinical Medicine in the Univer¬ 
 sity of Michigan, Department of Medicine, Ann Arbor. 
 
 XI — Varicella. 
 
 By William T. Councilman, M.D., Professor of Patho¬ 
 logy in the Medical School of Harvard Univ., Boston. 
 
 XII—Scarlet Fever. 
 
 XIII—Diphtheria. 
 
 By John H. McCollom, M.D., Assistant Professor of 
 Contagious Diseases in the Medical Department of 
 Harvard University, Boston. 
 
 XIV — Measles and Rubella ; The Fourth 
 
 Disease ; Erythema Infection. 
 
 XV — Whooping Cough. 
 
 XVI—Mumps. 
 
 By John Ruhrah, M.D., Professor of the Diseases of 
 Children and Therapeutics in the College of Physi¬ 
 cians and Surgeons, Baltimore. 
 
 XVII — Influenza. 
 
 By Frederick T. Lord. M.D., Assistant in Clinical 
 Medicine in the Medical School of Harvard Univer- 
 sity, Boston. 
 
 XVIII — Dengue. 
 
 By 1 iiomas D. Coleman, M.D., Professor of the Prin¬ 
 ciples and Practice of Medicine in the University of 
 Georgia, Medical Department, Augusta. 
 
 XIX — Cerebro-Spinal Fever. 
 
 By Henry Koplik, M.D., Attending Pediatrist to the 
 Mt. Sinai Hospital, New York. 
 
 XX—Erysipelas. 
 
 By James M. Anders, M.D., Professor of the Theory 
 3 i i(? 1Ce Medicine and Clinical Medicine in 
 the Medico-Chirurgical College, Philadelphia. 
 
 XXI- Lobar Pneumonia. Etiology and 
 Pathology. 
 
 XXII The Symptoms, Diagnosis and Prog¬ 
 nosis of Lobar Pneumonia. 
 XXIII The Treatment of Lobar Pneumonia. 
 
 By John H Musser, M.D., Professor of Clinical Med¬ 
 icine in theLUniversity 0 f Pennsylvania, Medical De- 
 partment, Philadelphia, and George William Nor¬ 
 ris, M.L ., Instructor in Medicine in the University of 
 Pennsylvania, Medical Department, Philadelphia. 
 
 
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Tki.ki'honk Connection 
 
 Office Houksi 
 
 9 TO 12 A. M. 
 
 CHARLES W. BTJJR W, M. U. 
 
 1327 Spruce Street 
 
 Philadelphia 5"“3I""06 « 
 
 Dr. William Osier, 
 
 7- Norham Gardens, 
 
 Oxford, England. 
 
 My dear Dr. Osler:- 
 
 I decided some time ago that I would never 
 again write any articles for any "book of composite authorship, 
 I did not suspect at that time that you were going to inflict 
 on the public a new"System of Medicine". Under the circum¬ 
 stances therefore, I will break my rule and shall be very glad 
 to write the Section on "Neurasthenia and the Traumatic Neuro¬ 
 ses" . 
 
 Very sincerely yours, 
 
 4 
 

 —w*t 
 
BALTIMORE, 
 
 I. THOMAS MCCRAE, 
 807 St. Paul Street. 
 
 CONSULTATION HOURS, 
 
 3-B P. M. 
 
 
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UK. CIIA1U.ES G-. STOCKTON, 
 430 Fbawkun Street, 
 Buffalo, N. Y. 
 
 Nov. 21 ,,1805. 
 
 My dear Dr.McCrae: 
 
 I am in receipt of your letter calling 
 attention to the articles for Dr.Osler* s new system of 
 medicine. After deliberation, I am disposed to ask you 
 to relieve me from writing the article on the spleen. The 
 introduction to the diseases of the digestive system, I shall 
 he glad to prepare for you. I have written to Dr.Osier 
 stating that I felt that some one else could do the spleen 
 better than I can, and I now make the same statement to you. 
 
 II I supposed that this would cause you any special embarrass 
 ment, I would reconsider ay decision. If it sKould so happen 
 that you would like to have our medical school represented 
 by another article, I have no doubt that I could suggest 
 a Buffalo substitute. 
 
 With many kind regards, I am 
 
 Yours very truly,. 
 
 Dr. Thomas MeC rae 
 
 Johns Hopkins Hospital, 
 Baltimore, Md. 
 
. THOMAS MCCRAE, 
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,R. THOMAS MCCRAE, 
 807 St. Paul Street. 
 
 CONSULTATION HOURS, 
 
 3*8 P. M. 
 
 BALTIMORE, 
 
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THOMAS MCCRAE, 
 807 St. Paul Street. 
 
 CONSULTATION HOURS. 
 
 3-6 P. M. 
 
 BALTIMORE, 
 
 J 'town '<)c~a/,vC.' Y» <4. 
 
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HENRY M. HURD, M. D. 
 
 Superintendent 
 
 The Johns Hopkins Hospital, 
 
 NORTH BROADWAY. 
 
 Baltimore, February 9 , 19#6.. 
 
 Dear Dr. Osier. 
 
 Lambert has sent on the section on cocaine and promises that the one 
 on morphia will follow very shortly. I shall send them on to the Leas at once. 
 
 I hope you will consider the remaining sections in the neurological volume 
 as soon as possible in order that we may get them settled. I rather hesitate to send 
 out the agreements with the definite number of pages stated until wc are exactly sure 
 of what is to go in. <1 do not know whether you have thought it well to have in some 
 
 of the extra articles, such as one on ophthalmology lu iv 
 
 , o h 
 
 I got your letter from the steamer; thank you for your inquiry about my 
 health. I got over the attack very well. -Many of the men have had a long siege of 
 
 it; our Dispensary staff especially has been much crippled. 
 
 I hope things are going well, and with kindest regards to the household and 
 yourself, * 
 
 . 
 
 Yours truly 
 
 1h 
 
 (Dryxc^d 
 
 JjL e C\ 
 
 
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-on. 134. 10,000—12-6-1905. 
 
 ft 
 
 The Johns Hopkins Hospital, 
 
 NORTH BROADWAY. 
 
 BALTIMORE. d.., .3 f.. .190 
 
 3ear Dr. Osier. 
 
 I have a letter from the Leas in re¬ 
 gard to Draig's illustrations for his article on ma¬ 
 larial fever. You may remember that in Way last I 
 bew your attention to them and questioned their be¬ 
 ing good enough. At the time you thought they would 
 lo all rirht to go ahead with. The Leas write ash¬ 
 ing if it might not be as well to use the old elates 
 >om the i oseital --eoorts. The only difference is 
 that -raig writes describing two varieties of aes- 
 
 
 ti vo-autumnal raresttes. 
 
 I have sooken to Troedel about having Oraig's 
 irawinp-s' imnroved by one of his assistants. He is 
 willing to oversee the matter, but the difficulty 
 seems to me, and he-feels the same, that considering > 
 the way the drawings are done, it is not going to be 
 nossible to make much out of them, although, of course 
 the general shades could be shown in a better way. 
 
 Mr. Lea ’"rites me that they will not go to 
 
LEP 
 
 III—Generc 
 
 jUSSELL H. Cb 
 ale University 
 e Sheffield Sci 
 
 IX—Diabet 
 rX—Diabet 
 XI— Gout. 
 
 Thomas B. Fi 
 M edicine, Johi 
 
 r/7 —Obesit 
 
 James M. Ani 
 P ractice of Me 
 Medico-Chirur; 
 
 -Introductio 
 
 Ludvig Hekt< 
 the University 
 College, Chicaj 
 
 -Typhoid Ft 
 
 -Pathology c 
 
 -The Sympt 
 
 -The Diagm 
 Fever. 
 
 -The Prop 
 Typho 
 
 —Typhus Fe 
 
 —Relapsing 
 
 Thomas McC 
 ate Professor o 
 in the Johns H 
 
 -Smallpox. 
 
 William T. C< 
 logy in the Med 
 
 — Vaceinatioi 
 
 George Dock, 
 tice of Medicine 
 sity of Michigar 
 
 — Varicella. 
 
 William T. Co 
 logy in the Med 
 
 —Scarlet Fe i 
 
 —Diphtheria 
 
 John H. McCc 
 Contagious pis 
 Harvard Univei 
 
 THl 
 

 mn 134. 10,000-12-6-1905. 
 
 u 
 
 
 The Johns Hopkins Hospital, 
 
 NORTH BROADWAY. 
 
 In 
 
 r^ 
 
 
 JALTIMORE, . 190 
 
 iross until they receive your article, which seems 
 o me foolishness, tut T transmit it to you in any 
 
 ase. 
 
 As I have to run away in a hurry I will pet 
 iss Reese to sign this. 
 
 With hind regards, 
 
 
 Yours truly 
 
 
 
 
 

BALTiMOREfebruary 16, 1906. 
 
 dr. THOMAS MCCRAE, 
 807 ST. Paul Street. 
 
 CONSULTATION HOURS, 
 
 3-6 P. M. 
 
 My dear Dr. Osier. 
 
 I am sending you with this a note of the ar¬ 
 ticles in Volume VII. which have still to be arranged for. I 
 have put the™ in in the order in which they are in the text¬ 
 book. I feel that we ought to try and straighten out this 
 section as soon as possible. 
 
 You did not say whether or not you had been able to see Dr. 
 
 Biggs in New York and interview him regarding his article. If 
 he will not take it is there any one else whom you have in mind 
 or shall we just let that drop? 
 
 I hope you have gotten back into harness again, which you 
 will probably find easier than a holiday in this country. 
 
 T^ith kindest regards, fo ^f\x t\ G U/l C 
 
 Yours truly 
 
 7 
 
 
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form 134. 10.000-12-6-1905. 
 
 dr. THOMAS MCCRAE, 
 807 St. Paul Street. 
 
 CONSULTATION HOURS, 
 
 3-6 P. M. 
 
 Baltimore, March 2, 1906. 
 
 Dear Dr. Osier. 
 
 I lave a letter from Lambert a day or two ago 
 saying that his manuscript was just about finished and that 
 he expected to ha/e it in this week, but it has not arrived 
 as yet. As regards Magrath I received a letter from Dr. 
 Councilman last wsek in which he advised sending an ultima¬ 
 
 tum by registered letter to Magrath, saying that if the manu- 
 script was not to hand this month, the matter would be taken 
 out of his hands* I did this, received a receipt for the 
 registered letter but have heard nothing thus far from him* 
 Councilman says that he himself will write the articles if 
 Magrath does not does not come up in time. I gave him until 
 March first and will wait a day yet. If no word comes then 
 I shall write to Councilman. It is a great nuisance but 
 perhaps in the erd we may be better off with Councilmans 
 article. I hope your introductory section is on the way, as 
 I think I told ycu the L©as felt they could not begin printing 
 until they had tlat. The notes regarding the articles on the 
 nervous system piobably reached you safely; I feel that we 
 ought to try and get those going as soon as possible. I shall 
 hope to hear fro* you in a few days. I hope you will approve 
 of my action regarding Magrath, but if there is no word from 
 
 him tomorrow I slall accept Dr. Councilman’s offer. 
 
 * \ 
 
 Matters iere are going on about as usual. I trust 
 everything is well at Oxford, and with kind regards. 
 
 Yours truly 
 
 
 % 
 
 o>v\cl^4 
 
 Jk% 
 
 
 " 4 = 
 
Form 134. 10,000-12-6-1905. 
 
 n 
 
 The Johns Hopkins Hospital, 
 
 NORTH BROADWAY. 
 
 BALTIMORE, 'ar.Cll... .L.Q..1G..*... 190 
 
 Dear Dr. Osier. 
 
 I wrote you a for/ days ago in regard 
 to Dr. Mae-rath. As I received no further word from 
 |im of any kind ind gave him some days longer than 
 me time mor.* iorod , I thought there mas no use of 
 [other ing any mme and I took Dr. Councilman's ad¬ 
 vice, notifying 'agrath that the article had been 
 
 put in other hards and "Tlti.ng Dr. Councilman that 
 
 io iu' 1 1 t/v 
 
 le mould recent tls offei^. .1 hone you approve of 
 this. The time is short and I did not like to delay 
 until I had heard from you. 1 ha-e notified the 
 
 boas rerardinn- it. 
 
 v n von remember a cha^ named Fagan mho came 
 
 tlkw> 
 
 from forth Adan*about a year ago? 
 
 myelitis of the snine and you got me to see him. 
 
 You may remember he behaved in a very curious way 
 at that time anc we rather commented on it. He 
 turned un the other day and is out at St. Agnes on 
 
 
 an 
 
 
 — 
 
 

form 134. 10,000-12-6-1905. 
 
 The Johns Hopkins Hospital, 
 
 NORTH BROADWAY. 
 
 JLO 
 
 BALTIMORE, 
 
 190 
 
 account of G. C. ?•/!. be says that ho has only been 
 t-frlnr it a short time lu+ T rather have my doubts. 
 
 aol it mould explain his actions of a year ap-o. 
 
 He looks well and I have a n^te from him sayinp he 
 fras doinr very well. 
 
 With kindest regards to you and all the 
 
 household , 
 
 
 v ’ours ve^y truly 
 

 
807 St. Paul Street. 
 
 CONSULTATION HOURS, 
 3-5 P. M. 
 
 Baltimore, March 16, 1906. 
 
 fl 
 
 Dear Dr. Osier. 
 
 The copy of Bayle f s Medical Biography arrived 
 safely; very many thanks for your kindness in sending it. I 
 did not have it and am delighted to possess it. It was exceed¬ 
 ingly good of you to think of it and keep me in mind. 
 
 I have just received a letter from Dr. Councilman in which 
 he asks if there would be any objection to his changing the or¬ 
 der which we laid out to be observed in the arrangement of sub¬ 
 jects. He suggests the following:- historical, general charac¬ 
 teristics of epidemics, symptoms, complications and sequelae, 
 types of the disease, treatment, pathological anatomy and his¬ 
 tology, parisitology, small-pox in animals and experimental work. 
 He says that his method is to consider the pathology after the 
 patient has died and not before. I do not know w v at view you 
 
 will take but I expect we better let Councilman gang his ain 
 <( ^ 
 
 gait and do as he wishes. I am simply saying to him that I am 
 
 writing you and in the mean time he had better go ahead with the 
 
 arrangement which he suggests. 
 
 I hope you have kept in mind specially the following points 
 
 about which I wrote:- the settling of the men for the remaining 
 
 subjects of the neurological volume and that you have also written 
 
 to Boggs regarding the section that you thought it was well for 
 
 him to take. There is ono matter that perhaps we ought to do 
 
 ( 
 
 something more about and that is a section on the Leishman—Dono¬ 
 van bodies. You once spoke of leaving that off until the sixth 
 volume, as there might be a good deal more work done by then. 
 
 You my have thought otherwise of it since. 
 

 f^r 
 
807 St. Paul Street. 
 
 CONSULTATION HOURS, 
 3-6 P. M. 
 
 *2 
 
 BALTIMORE, 
 
 I have been quite busy and was up in Hamilton the other day, 
 seeing a typhoid patient with Glassco. I also saw 01mstead ? s 
 
 brother in consultation with Dr. Malloch and was very much im~ 
 
 rv 
 
 pressed by the hard-headed sense that he has. Olmstead's brother 
 had a severe septicaemia but was rather better when I left* 
 
 I hope that matters are going well with you, and with kind¬ 
 est regards. 
 
 Yours truly 
 
 if ^ ^ ^ 
 
 
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/=Y 
 

 OR. THOMAS MCCRAE, 
 807 St. Paul Street. 
 
 CONSULTATION HOURS, 
 
 Baltimore, March 27 , 1906 
 
 Dear Dr. Osier 
 
 I received your letter of the sixteenth yester¬ 
 
 day. I had already written Dr. Councilman suggesting that he 
 might have some one to help him with the clinical part of hid 
 article, but his reply rather suggested that he was going to do 
 it himself. I had a letter from Mr • Lea a few days ago in 
 which he says they are still having trouble with the strike but 
 that they expect to be able to go ahead all right very shortly. 
 Lambert promises the remaining section of his positively this 
 week. Mr. Lea wrote me that he did not feel like starting any¬ 
 thing until they had your introduction, which does not seem to be 
 necessary. 
 
 You do not say anything in regard to the question of illus¬ 
 trations for Craig 1 s article, about which I wrote you some time 
 ago. I hope the letter did not go astray. If you should find 
 that you had not answered it will you do as soon as convenient, 
 please. 
 
 I was sorfy to hear that you had had so much trouble with a 
 cold. Nearly every one here has been in the same boat* I do 
 
 not think we have ever had a winter with tonsillitis and influ— 
 
 vW* tin floods 
 
 enza so prevalent as this year. 3arker is still in bed^and I 
 think Thayer has decided that the arthritis is rheumatic. He 
 looks better arid I think the effusion is pretty well gone. We 
 are having the most infernal weather and the spirits of all the 
 
 patients are very low. 
 
 ky kindest regards to all the household. With best wishes 
 
 Yours truly 
 
rj 
 
0 R. THOMAS MCCR 
 807 St. Paul Street. 
 
 CONSULTATION HOURS. 
 3-5 P. M. 
 
 £7 
 
 1cC<l iU\xHU\ 4it m**f C^ veuf 
 
 fkxCh'ni-vx 
 
 BALTIMORE, ^arch 70 , 1906. 
 
 
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 Dear Dr. Os lor. 
 
 7/u Cu Cf* 
 
 UtU- t(T 
 
 CuX~«. <4 C&-6 ru ** ^ ^ 
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 i*' y, 
 
 I have received a letter from Lusk in Toronto 
 asking me to contribute an article for a special number of the 
 British Medical Journal in July. He said they wished articles 
 from as many Canadians as possible and said that you had prom¬ 
 ised to contribute. I have written that I have so much on hand 
 that I do not care to tackle a new article, but I have gotten 
 on fairly well with the carcinoma of the stomach material, hav¬ 
 ing extracted all the hundred and fifty extra cases, and I 
 thought perhaps we might send that in together. You may however 
 think it better to keep all that material for the second edition 
 
 of the monograph. 
 
 There is one matter that we have perhaps let escape our 
 attention, that is, the short section on blackwater fever which 
 you were going to write to add to Craig's article. You may have 
 done it before this. If not I have not said anything to the 
 Leas about it and I should think it could be easily sent in a 
 little later. 
 
 I hope you have kept the question of the remaining as¬ 
 signments for the neurological volume in mind and have also 
 written Boggs regarding his writing a section on a number of 
 the minor infections, febricula, etc. I sent you a note a few 
 days ago regarding the question of deciding about the illustra¬ 
 tions for Craig's article. 
 
 I trust you are feeling quite well again, and with kind 
 
 Yours very truly 
 
 regards, 
 

 
 
 
 
 
 
 
V 3 
 
 OR.THOMAS MCCRAE, 
 
 1*1 St. paul Street. 
 
 CONSULTATION HOURS, 
 3-6 P. M. 
 
 E, 1 
 
 BALTIMORE, 
 
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 CONSULTATION HOURS, 
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 807 St. Paul Street. 
 
 CONSULTATION HOURS, 
 3-6 P. M. 
 
 
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 3-8 P. M. 
 
 BALTIMORE, j 
 
 
 Dear Dr. Osier: 
 
 Yours of 4 .he ?lst. arrived yesterday, 
 and I hope that you v.'ill be able to get the manuscript 
 off as you expected. I 'ope that you have not lost 
 sight of the section n the "Diseases of the Artcr- 
 ios" . I have sent in several aneurism pictures 
 and air. trying to et a couple of x-ray plates from 
 Baet j er . 
 
 Dr. Garrod sent his manuscript on but ra-ites 
 that he has not done the sections on", alformations" 
 and "Circulatory Disturbances". Ho evidently 
 thinks that he lot me know of this before, but I 
 can not find that I have any word of it. I shall 
 have to try and see if I can pet one of the men 
 hero to do it. I suppose if the worst comes I 
 can do it myself. I should thin'- that we ought 
 to be able to get out the volumes quicker than you 
 suggest. V'ith your manuscript on hand we can man¬ 
 age vol. IV very quickly, and Vol. 7 is about one- 
 half in galley. I suppose tha' you remember that 
 you have sections in Vol. 71 on the "Trophic Con- 
 ditions . 
 
 Everything here goes on as usual, ith 
 
 kind re ards to you all > 
 
 Yours trur , 
 
807 St. Paul Street. 
 
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 3-6 P. M. 
 
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CONTENTS. X7 
 
 % 
 
 PAGE 
 
 Arterio-venous Aneurism.788 
 
 Congenital Aneurism.788 
 
 SECTION VIII. 
 
 DISEASES OF THE BLOOD AND DUCTLESS GLANDS. 
 
 I. Anaemia.789 
 
 Secondary Anaemia.789 
 
 Primary or Essential Anaemia. 792 
 
 II. Leukaemia. . • 8 ^2 
 
 HI. Hodgkin’s Disease . ..809 
 
 IV. Purpura. 814 
 
 V. Haemophilia. 81 ^ 
 
 VI. Scurvy.. . 821 
 
 VII. Status Lymphaticus. 8 ~6 
 
 VIII. Diseases of the Suprarenal Bodies.828 
 
 IX. Diseases of the Spleen.. 832 
 
 X. Diseases of the Thyroid Gland.835 
 
 Goitre. 8: ^ 
 
 Tumors of the Thyroid. 
 
 Exophthalmic Goitre. 836 
 
 Myxcedema. 84 ^ 
 
 XI. Diseases of the Thymus Gland.843 
 
 SECTION IX. 
 
 DISEASES OF THE KIDNEYS. 
 
 I. Malformations.846 
 
 II. Movable Kidney.846 
 
 III. Circulatory Disturbances ..849 
 
 IV. Anomalies of the Urinary Secretion.850 
 
 1. Anuria.850 
 
 2. IIa?maturia.851 
 
 3. Haunoglobinuria.852 
 
 4. Albuminuria.854 
 
 5. Pyuria (Pus in the Urine).858 
 
 6. Chyluria (Non-parasitic).859 
 
 7 Lithuria.859 
 
 8. Oxaluria.861 
 
 9. Cystinuria.861 
 
 10 Phosphaturia ... 862 
 
 11. Indicanuria.863 
 
 12. Melanuria.863 
 
 13. Pneumaturia. .... 864 
 
 14. Other Substances ..864 
 
 V. Uraemia ..865 
 
 VI. Acute Bright’s Disease. .... 869 
 
 VII. Chronic Bright’s Disease.874 
 
 Chronic Parenchymatous Nephritis.875 
 
 Chronic Interstitial Nephritis. . 877 
 
 VIII. Amyloid Disease.884 
 
 IX. Pyelitis.886 
 
 X. Hydronephrosis... 889- 
 
XVI 
 
 CONTENTS. 
 
 XI. Nephrolithiasis (Renal Calculus). 
 XII. Tumors of the Kidney 
 
 XIII. Cystic Disease of the Kidney 
 
 XIV. Perinephric Abscess 
 
 PACK 
 
 891 
 
 896 
 
 898 
 
 900 
 
 ■Aw 4a - 
 
 SfiLUcK 
 
 2 7\£mC ttj 
 
 Z y\\ 
 
 System 
 
 SECTION X. 
 
 DISEASES OF THE NERVOUS SYSTEM. 
 
 I. General Introduction. 
 
 II. System Diseases. 
 
 --?1. Introduction. 
 
 ^-Diseases i*f-the: 
 
 I * w ‘ rmioto v -Ataxia 
 
 8. Diseases of the Efferent or Motor Tract 
 
 Of the Whole Tract. 
 
 ^—- Progressive (Central) Muscular Atrophy . 
 
 Bulbar Paralysis. 
 
 Progressive Neural Muscular Atrophy 
 ^— The Muscular Dystrophies .... 
 
 System Diseases of the Upper Motor Segment 
 Spastic Paralysis of Adults .... 
 
 Spastic Paralysis of Infants.... 
 
 901 
 
 919 
 
 919 
 
 920 
 920 
 928 
 928 
 928 
 
 932 
 
 933 
 933 
 
 936 
 
 937 
 
 938 
 
 
 
 ctt - 
 
 
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 Hereditary Spastic Paraplegia.940 
 
 Erb’s Syphilitic Spinal Paralysis.940 
 
 ijSecondary Spastic Paralysis.941 
 
 ^ " IIHysterical Spastic Paraplegia.941 
 
 System Diseases of the Lower Motor Segment.941 
 
 Chronic Anterior Polio-myelitis.941 
 
 Ophthalmoplegia.942 
 
 Acute Anterior Polio-myelitis.942 
 
 Acute and Subacute Polio-myelitis in Adults . . . . .946 
 
 Acute Ascending (Landry’s) Paralysis.946 
 
 Myasthenia Gravis.947 
 
 4. Combined System Diseases.947 
 
 Ataxic Paraplegia.948 
 
 Primary Combined Sclerosis (Putnam).949 
 
 Hereditary Ataxia (Friedreich’s Ataxia).949 
 
 Progressive Interstitial Hypertrophic Neuritis of Infants . . . 951 
 
 Toxic Combined Sclerosis.951 
 
 III. Diffuse Diseases of the Nervous System.951 
 
 1. Affections of the Meninges ..951 
 
 Diseases of the Dura Mater (Pachymeningitis).951 
 
 Hemorrhagic Pachymeningitis.952 
 
 Diseases of the Pia Mater.954 
 
 Simple Meningitis of Infants.957 
 
 2. Scleroses of the Brain.957 
 
 In sular Sclerosis.959 
 
 8. Chronic Diffuse Meningo-cncephalitis.960 
 
 .964 
 
 tU 
 
 IV. Diffuse and Focal Diseases of the Spinal Cord 
 
 
 Topical Diagnosis 
 Affections of the Blood-vessels 
 Congestion 
 
 Anemia .... 
 Embolism and Thrombosis 
 
 964 
 
 966 
 
 966 
 
 966 
 
 966 
 

 CONTENTS. 
 
 XVII 
 
 tkty/uZ 
 
 Endarteritis. 
 
 Haemorrhage into the Spinal Membranes 
 Haemorrhage into the Spinal Cord 
 C ai s s on D i s eas e . 
 
 967 
 
 967 
 
 968 
 
 969 
 
 970 
 
 972 
 
 973 
 
 ftiV 
 
 8. Compression of the Spinal Cord 
 
 Lesions of the Cauda Equina and Conus Medullaris 
 
 4. Tumors of the Spinal Cord and its Membranes . 
 
 5. Syringomyelia.975 
 
 6. Acute Myelitis. 
 
 Diffuse and Focal Diseases of the Brain . 
 
 976 
 
 979 
 
 f A * a. a opium 
 
 fefrU (2. Aphasia 
 
 1. Topical Diagnosis ..979 
 
 988 
 
 Affections of the Blood-vessels.994 
 
 
 994 
 
 
 Ilyperamiia. 
 
 Anaemia.095 
 
 GSdema of the Brain.997 
 
 Cerebral Haemorrhage.997 
 
 . Embolism and Thrombosis.1008 
 
 1 Aneurism of the Cerebral Arteries . . . . . . .1013 
 
 \ Endarteritis.1014 
 
 Jj^hrombosis of the Cerebral Sinuses and Veins.1015 
 
 Scud*** —{Hemiplegia in Children.1017 
 
 4. Tumors, Infectious Granulornata, and Cysts of the Brain . . . 1020 
 
 5. Inflammation of the Brain.1024 
 
 Acute Encephalitis.1024 
 
 Abscess of the Brain.1025 
 
 ^ 6. Hydrocephalus.1028 
 
 VI. Diseases of the Peripheral Nerves.1031 
 
 1. Neuritis (Inflammation of the Bundles of Nerve Fibres). . . . 1031 
 
 2. Neuromata.1037 
 
 3. Diseases of the Cerebral Nerves ‘.1038 
 
 Olfactory Nerves and Tracts.1038 
 
 Optic Nerve and Tract.1039 
 
 Lesions of the Retina.1039 
 
 Lesions of the Optic Nerve.1040 
 
 Affections of the Chiasma and Tract.1041 
 
 Affections of the Tract and Centres ....... 1042 
 
 Motor Nerves of the Eyeball.1045 
 
 Fifth Nerve.. . ^. . . 1050 
 
 Facial Nerve., . .1051 
 
 Auditory Nerve.1056 
 
 The Cochlear Nerve.1056 
 
 The Vestibular Nerve.1058 
 
 Glosso-pharyngeal Nerve.1059 
 
 Pneumogastric Nerve.1060 
 
 Spinal Accessory.1063 
 
 Hypoglossal Nerve.1066 
 
 Diseases of the Spinal Nerves.1067 
 
 Cervical Plexus.1067 
 
 Brachial Plexus.1069 
 
 Lumbar and Sacral Plexuses.1072 
 
 Sciatica.1073 
 
 VII. General and Functional Diseases.1075 
 
 W^AeutcH D e li rir i m f BaU's Mani a).1075 
 
 B 
 
 J 
 
 
XV111 
 
 CONTENTS. 
 
 FAGC 
 
 2. Paralysis Agitans.1076 
 
 Other Forms of Tremor.. 
 
 3. Acute Chorea (Sydenham’s Chorea; St. Vitus’s Dance). . . . 1079 
 
 4. Other Affections described as Chorea.1088 
 
 \6 i Infantile Convulsions (Eclampsia).. 
 
 - 6 . Epilepsy.. 
 
 ' / 7. Migraine.H 02 
 
 8 . Neuralgia.1104 
 
 9. Professional Spasms; Occupation Neuroses.HO 7 
 
 10. Tetany. 1109 
 
 11. Ilysteria.im 
 
 12. Neurasthenia. 1122 
 
 13. The Traumatic Neuroses. 1132 
 
 14. Other Forms of Functional Paralysis . . . . f . .1136 
 
 Periodical Paralysis. 
 
 Astasia; Abasia. 1130 
 
 VIII. Vaso-motor and Trophic Disorders. 1137 
 
 r \. Raynaud’s Disease. 1137 
 
 . 2. Erythromelalgia. 1139 
 
 3. Angio-neurotic (Edema.1140 
 
 ^ Facial Hemiatrophy.* .1141 
 
 f 6 . Acromegaly.1142 
 
 Osteitis Deformans ..1144 
 
 Hypertrophic Pulmonary Arthropathy.1144 
 
 Leontiasis Ossea.1145 
 
 Micromegaly.1145 
 
 t* ^_ 6 . Scleroderma.1145 
 
 V *°' Ainhum.1147 
 
 
 SECTION XI. 
 
 DISEASES OF THE MUSCLES. 
 
 I. Myositis. 1148 
 
 II. Myotonia (Thomsen’s Disease).1149 
 
 III. Paramyoclonus Multiplex. 1150 
 
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