THERAPEUTICS OF THE DAY BY DR W.STENS 8/6 B 477164 DUPL ARTES LIBRARY 1837 SCIENTIA VERITAS OF THE UNIVERSITY OF MICHIGAN E. PLURIBUS UNUM SI-QUAERIS-PENINSULAM AMDENAME CIRCUMSPICE #615, 582 (1) # THERAPEUTICS OF THE DAY. ! THERAPEUTICS OF THE IN OF THE DAY; A Series of Letters BY 96490 DR. WILHELM STENS, SANITARY COUNCILLOR OF HIS MAJESTY THE KING OF PRUSSIA, AND PHYSICIAN IN ORDINARY TO H. R. H. PRINCE ALBRECHT OF PRUSSIA. TRANSLATED FROM THE GERMAN, WITH THE SPECIAL PERMISSION OF THE AUTHOR, BY HENRY ST. CLAIR MASSIAH. From smallest causes great effects will rise; With skill array all things in pleasant guise: Up, and at work! thy glance, like eagle's, clear; Truth's dome to raise, that foes may cease to sneer! SECOND EDITION REVISED. LONDON: PRINTED BY J. WERTHEIMER AND CO., CIRCUS PLACE, AND TO BE HAD OF ALL HOMEOPATHIC CHEMISTS AND BOOKSELLERS. 1863. LONDON: PRINTED BY WERTHEIMER AND CO., CIRCUS PLACE, FINSBURY CIRCUS. ΤΟ WILLIAM LEAF, Esq., THE EARLIEST PATRON OF HOMOEOPATHY IN ENGLAND, AS A TOKEN OF RESPECT AND GRATITUDE, THIS BOOK OF DR. STENS, IS DEDICATED BY THE TRANSLATOR. SOME future page in Britain's lore shall tell Of all that LEAF has done, and done so well. When Homœopathy pervades the earth, All will know how he tended, at its birth,* The gentle science; and with fervour true Watch'd its slow progress, till it throve and grew; Spreading its healing influence, like oil, Upon the ailing sons of Freedom's soil. Then, LEAF, in grateful memories enshrined, And ranked with benefactors of mankind, Than his, leaves not a nobler name behind. *The introduction of Homœopathy into England is here meant. TO HIS IMPERIAL HIGHNESS THE ARCHDUKE JOHN OF AUSTRIA, PRINCE ROYAL OF HUNGARY, BOHEMIA, ETC., ETC., ETC,, FIELD MARSHAL OF THE AUSTRIAN ARMY, THE HIGH AND POWERFUL PROMOTER AND PROTECTOR OF HOMEOPATHY, THE high favour which your Imperial Highness has conferred on Homoeopathy, as proved by many facts, has now procured me the agreeable surprise of being allowed to place the name of your Imperial Highness at the head of this work. Your high patronage of the deep truth and great usefulness of the Hahnemannian doctrine will, no doubt, be as a shining light, spreading its rays afar, for the welfare of humankind. To me, however, it has been a great event to have obtained, through this Dedication, the opportunity of assuring your Imperial Highness of the deep feelings of gratitude which all friends and representatives of Homœopathy entertain for your Imperial Highness. With the profoundest respect, I am, Your Imperial Highness's Most obedient, humble Servant, DR. STENS. BONN ON THE RHINE, 4th October, 1854. NOTICE. I HAVE endeavoured, in my translation, to preserve accuracy at the expense of style. My task has not been an easy one; and, when my efforts are weighed in the balance with those of more experienced trans- lators in the same cause, I trust I may be judged leniently. Dr. STENS' "Therapeutics" has been translated not only for Medical Homœopathists, but for intelligent laymen, with the intention of propagating the truths of Homœopathy, and not for austere critics, who would do well to remember the French proverb-"La critique est aisée, mais l'art est difficile." 1 TRANSLATOR'S PREFACE. Many are the books which have been written in favour of Homœopathy, and which have proved that this treatment is more advantageous to the Patient than that of Allopathy; but this is not sufficient, for how can we expect Physicians of the Old System, and that part of the Public which follows them, to abandon the Old School, unless it is clearly shown to them that the very foundations of Allopathy are rotten at the core. The public have a right to be enlightened upon every point which regards health, to know to what treatment they entrust the lives of those dearest to them; and feeling the necessity that this should be carried into effect, I have translated Dr. Stens' work. B DR. STENS' PREFACE. Go into the world, my Book, and do thy duty as I did mine in writing thee. Thy bed will not be of roses; but, fed on the marrow of facts, thou possessest the courage and strength that are required to combat, worthily and perseveringly, in the great battle for truth. I am convinced that neither praise nor contempt will make thee deviate from the path on which thou art destined to lead suffering humanity to health; for thy intentions are of the purest and noblest, and thou carriest with thee the most approved and efficacious of remedies. CONTENTS. LETTER I. Physiology-Generation-Breathing-Digestion LETTER II. Formation and Dissolution of Matter • • PAGE 7 17 LETTER III. The Nerves. Retrospect 35 LETTER IV. Pathology 47 LETTER V. Materia Medica 61 LETTER VI. Therapeutics.—The Antipathic or Revulsive Method . LETTER VII. The Physiological Method.—The Materialists LETTER VIII. Inflammation.- Theories and Treatment of the same.- The true Science LETTER IX. Discovery of the Homœopathic Law of Cure.-Rules for Experiment. 81 99 . 116 • 137 CONTENTS. LETTER X. The Materia Medica of Homœopathists PAGE . 153 LETTER XI. The Pathology of Homœopathists . . 163 LETTER XII. Therapeutics of Homœopathists . 172 LETTER XIII Historical evidence in favour of the principle of Similarity. 196 LETTER XIV. The Theory of the Dose 209 LETTER XV. The Minute Doses of Homœopathists. 219 LETTER XVI. Results of Homœopathic Practice 254 LETTER XVII. History of Homœopathy-Hahnemann's Life and Labours. 273 LETTER XVIII. Details as to how Homœopathy is combated, and refutation of the objections adduced against it • LETTER XIX. The Self-Dispensing of Homœopathists LETTER XX. Survey of Homœopathy-Its Position.-What have Homœo- pathists to do? 292 322 331 FIRST NEGATIVE" PART. Page 84, line "1 126, "" "" 148, 11 168, "" 11 CORRIGENDA. 5, for have been, read are to be. 4, for re-organising, read recognising. 6, for its, read this. 19, for diseases, locked, read diseases arc locked. 181, 182, 185, 186, instead of "Petechial Fever," read "Petechial Disease" (Hæmorrhoea Petechialis). "" 217, "" 9, for sodium, read iodium. "" "1 : 220, 28, for to recognise, read not to recognise. " 242,,, 336, "" 18, for not immeasurable, read invisible. 13, for lectures, read lecturers. LETTER I. PHYSIOLOGY-GENERATION-BREATHING- DIGESTION. THERAPEUTICS is the rich ripe fruit of Medical science. The separate branches of this noble science only grow and bud forth as tending to its final development and maturity. They exist not for themselves, but on its account; and concentrate in it as in their acknowledged and absolute centre. He, and he alone, who can apply scientifically and conscientiously the various branches of the art, deserves to be called a Physician. He who does not, may be a clever and distinguished investigator of nature, but he has not the slightest claim to the title of Doctor. The art of healing is the very pulse of Medical Science, for by it only are its truth and value recog- nised. To cure effectually, two things are absolutely necessary; firstly, a knowledge of the disease, and secondly, an intimate acquaintance with the remedy through which the cure is to be effected; in other words, one should be acquainted with Pathology and with the Materia Medica. To have a clear under- standing of the diseased conditions, everybody should have a thorough knowledge of the healthy ones. It is therefore of the utmost importance to thoroughly understand Physiology, which teaches to discover the laws of life when in health. It is the easiest point to start from, in order to value properly the idea of the various changes occurring in the functions of the diseased conditions, and of those taking place in the normal oncs of life, without, however, being an absolute rule for those influenced by disease. 8 Desirous, as I know you to be, to form a correct opinion of the Therapeutics of the present time, it is highly important that you should first have a clear insight into Physiology, and the more especially so, be- cause in our days the physiological school is entirely guided by it, cloaks itself with arrogance, in the semblance of profound learning, and affects to look down on all other theories with utter contempt. I will merely point out to you the principal features of Physiology, and I trust to do it in a way which will enable you to glean sufficient information to form an opinion of what you can and may expect from it. Let us begin with the theory of Generation. The form and chemical combination of the ovum and sper- matozoa are laid before you; the way they take, before meeting, is described, as well as the place where the embryo develops itself; but the process of organisa- tion, and its origin or cause, remain hidden in total obscurity. As regards the nature of these spermatozoa, too, the greatest indecision prevails. Some say they originate in vesicles, others think they are formed in capsulary mucous bags, in mucous membranes, or in fibres. The mother cell is said to be composed of, or to contain two vesicles, the one within the other (in ein- ander geschachtelten Bläschen), each of different chemical contents. The proof of this chemical difference is utterly wanting—it is, therefore, a mere statement of supposed chemical and mechanical facts! Thus our knowledge of generation rests on vague statements of what is chemical and mechanical which accompanies the organic process. This is, indeed, all we know on this important point. The first exciter, the real generative act, remains a mystery to us. Even in these statements, such as they 9 are, much remains to be revealed, and the most various views are taken of them. With regard to the theory of Respiration, we are first told of the motion of the respiratory organs; of the duration of inhalation and exhalation; of the in- fluence which divided nerves have upon the process of breathing; of the power with which the air is expelled from the lungs; of the quantity and chemical quality of the inhaled and exhaled air; of the proportion of oxygen inhaled to carbonic acid exhaled: whereas breathing itself is explained to be a purely chemical pro- cess, and the first breath drawn is said to be caused by the oxygen of the atmospheric air, and not by any internal organic act of life itself. But even this chemical explanation leaves us in the dark as to the components from which the exhaled car- bonic acid and the water are derived-whether from the albumen, the fat, or the sugar that has entered the body, for they may arise from all three. To obtain a clearer insight of the internal process of organisation, a thorough knowledge of the origin is, however, of the utmost importance. In opposition to this chemical view, we have one of a more organic nature; which regards breathing as the cause of the blood's formation, giving the very life to it and particularly to the blood-globules. In this case oxygen is regarded as the very principle of life, and carbonic acid as its residue. Therefore, according to this theory, the absorption of oxygen does not depend on the quantity of carbon and iron (as LIEBIG maintains in his chemical view of the matter); but on the amount of animation or vitality in the membranes of the blood-globules. The old worn-out ones, abounding in carbon and iron, con- 10 sequently no longer absorb oxygen gas, or exhale carbonic acid; whereas the new ones, containing as yet but little colouring matter, but possessing extremely ensitive membranes, absorb a great deal of oxygen, and exhale as much carbonic acid. It cannot be denied that this view is by far more organic, and that it would approach still nearer to the organic truth, if the influence of nervous textural life, and the organic intervening action of the one into the other, had not been entirely lost sight of. Unfortunately here, as it too often happens elsewhere, the blood, a chicf supporter of life, is made the sole vehicle of it; organic unity and truth are thus destroyed, and clear and distinct knowledge is rendered utterly impossible. We will add a few remarks as to the quantity of exhaled carbonic acid. It increases from childhood to puberty. On the appearance of the menses, this in- crease ceases : on their cessation, it augments again slightly. In advanced age, it decreases in both sexes. On an average it is one-third less in woman than in man. In the same proportions more carbonic acid is exhaled during vegetable diet, than while living on animal food. A meal increases it. A greater amount of heat diminishes the quantity; and bodily motion, like every other effort of strength, increases it. During sleep it is considerably diminished, and less oxygen is inhaled. All this is, beyond doubt, very interesting indeed; but, as you see, it treats only of the conditions and refuse of life. Life itself is not mentioned or alluded to in any way whatever; and the organic act of breathing is not explained. Let us now speak of the Blood, that most precious of all fluids, the liquid organisation. Its principal 11 component parts-that is, those which have not sprung from the backward or retrograde formation of the materials of the animal body-may be considered as the elementary bodies of all the other parts of the organism. I feel bound to draw your attention to this difference, as the blood is not only the very fount of life, but at the same time its cloaca. Remember, also, that there is a liquid in each vessel, from which the chief materials of the different textures may be formed. The blood is, therefore, the main point of the generally distributed parts of animals. In the digestive organs, we may partially follow up the development and changes from which the blood is finally composed or derived. But if you would understand these, we must go back to food. What is Food? Every organic or inorganic com- bination, which sufficiently resembles the principal component parts of the blood, to be able to be changed into it, by the process of digestion. The chief component parts from which the blood is derived, are:- A. Inorganic matter. B. Organic matter, free from nitrogen (fat). C. Organic matter, containing nitrogen, such as albumenous substances. The ingredients of food are divided in the same manner; they are either organic or inorganic; the first, either free from, or containing, nitrogen. Among the inorganic aliments, water and the alkaline and earthy phosphates rank first. As in plants, phosphoric acid predominates over sulphuric acid in the blood. But the blood contains more soda than potassia, more 12 lime than magnesia, and a great deal of chlorine. It is exactly the contrary with the vegetables that are used for food. Next to the inorganic aliments are oxide of iron, alumina, silica, fluor-calcium, and silicic acid. The aliments free from nitrogen are divided into fat-formers and fat. The first are starch, dextrine, gum, sugar, and cellular texture. All these bodies are formed of equal parts of carbon, hydrogen and oxygen; they are, there- fore, isomeric bodies, only the sugar sorts contain rather more hydrogen and oxygen, both in the water- forming proportion. The fatty matters are elaïn, margarine, stearine, the corresponding acids, soaps, and butyric acid. The aliments containing nitrogen are albumen, pea-flour, gluten in a narrower sense, and vegetable glue. They are all composed of equal parts of nitrogen, carbon, hydrogen and oxygen, and contain besides these, sulphur and phosphorus, with the ex- ception of the vegetable glue, which is free from the latter, while the pea-flour contains the most of it. These nitrogenous aliments are the chief agents in the formation of the blood, and are also principally prevalent in those parts of plants in which the quickest change of matter occurs. The value of eatables must not, however, be judged according to their amount of nitrogen, as is too often. the case; for animals which were entirely nourished with albumenous substances soon died. Food requires a judicious distribution of inorganic aliments, fatty matters, fat-formers, and albumenous combinations. The process, by which these aliments are changed into blood, is called digestion. This change consists, either in a mere dissolving, or 13 in a combined solution and change, inasmuch as the articles of food are not of the same composition as the blood itself. Thus, salt is dissolved, that it may be carried into the vessels as an essential ingredient of the blood Starch not only requires to be dissolved, but its pro- perties and combinations have to be changed. These changes take place through the digestive fluids; saliva, gastric juice, bile, the pancreatic juice, and intestinal mucus. The peristaltic motion of the coats of the stomach and intestines assists, materially, the complete intermixture of these liquids, causing, as it were, a continuous displacement of the contents. The inor- ganic ingredients pass by solution into the blood, and a few salts only are changed and decomposed. Many salts and earths are found in the excrements and urine, that have undergone no change. Water is also met with in the same state as when it entered the body. But, mark well, it has by no means been proved whether parts of these salts, and of this water, have not entered into other combinations. Nay, it is highly pro- bable that the salt supplies soda to the body; that sulphates, viz., Glauber's salt, assist in forming sul- phuretted hydrogen in the intestines; that the water in the body returns to its primitive element, and, as such, has a share in forming the various combinations of ammonia. This is most important; for you perceive clearly, that under such circumstances no valid conclusion can be drawn from the salts met with in the analysis of food, excrements, and urine, nor from the changes which have occurred in the body, nor from the newly-formed bodies, which have quite different properties from the 14 original ones, though we often find such conclusions in the theory of the formation and change of matter, and in the attempted Materia Medica, in which the effects of medicine are described according to the analysis of the excrements, completely mistaking, by so doing, the inter- nal organic life. How absurd is it to conclude, because Glauber's salt has been taken, and afterwards found in the excrements, that it has passed as such through the organisation; whereas it has, in reality, at one time caused the formation of sulphuretted hydrogen, and at another that of sulphuric acid, ammonia, or carbonate. of soda, accordingly as the division and formation are caused by the different excitors. Thus alkaline sulphates become sulphurets of potassium in the intestines-bodies of entirely different properties and effects. The solution of salts, if they are easily dissolved, is caused by water. Those which are more difficult to dissolve, such as oxide of iron and the earthy salts, are dissolved by the free acids of the stomach. All starchy bodies are changed, by the action of the saliva, pan- creatic juice, and intestinal mucus, into dextrine, sugar, lactic, and butyric acid, and thus become soluble. The part which the bile plays in this, as well as its real destination and functions, are as yet obscure, and yet so many methods of healing have been founded on its supposed properties, that, seduced by such indica- tions, real horse-treatment has been inflicted on the poor patient. The neutral fats are changed into soaps and glycerine, by the action of the pancreatic juice and the intestinal mucus. The transforming process of the saliva is not altered by a free acid; therefore, when swal- lowed, its action is continued. The albumenous bodies. 15 are dissolved by the gastric juice and the intestinal fluid. When too much saliva is swallowed, it in- terferes with, or completely annuls this action. In a similar manner, the least admixture of bile with the gastric juice completely annuls the dissolving pro- perties of the latter, although the acid re-active power remains. are Thus chyme already contains salts, sugar, and albu- men dissolved. In the small gut where chyme becomes chyle, lactic acid, butyric acid, and soaps added. Thus, inorganic elements, fat, fat-formers, and albumen are changed, and, through this change, partially rendered liquid. This liquefaction is abso- lutely necessary for them to pass into the blood. The mucous membranes of the digestive organs, as well as the coats and chyle vessels and veins, which lie behind, cause this change. The thinner fluid of chyme enters into the more condensed one of blood, and is mate- rially assisted in this by the evaporation occurring at the surface as a direct pressure. During digestion, the blood becomes richer and firmer in its component parts. Its contents, with respect to the inorganic elements, are less in the intestinal canal than in the stomach, and its earthy parts have sensibly diminished. Thus already a greater portion of the inorganic elements enter into the chyle and blood-vessels while in the stomach. Chyle mixed with lymph enters the blood, and is there completely turned into the latter. As regards the digestive fluids, I will only remark to you, that saliva, the pancreatic juice, and the intestinal mucus, have an alkaline re-action; the gastric juice, however, has an acid re-action; but through which acid has not yet been proved. - According to some investigators, the gastric juice 16 undoubtedly contains lactic acid, hydrochloropepsic acid probably; and nitric acid possibly; whereas acetic and butyric acids, are but occasionally encoun- tered. In opposition to this, according to the latest researches of BIDDER and SCHMIDT, the gastric juice of carnivorous animals in a fasting condition contains only free hydrochloric acid, but not a particle of lactic, or any other organic acid. That of vegetarians contains free hydrochloric acid, besides small quantities of lactic acid, which last, however, are only derived from starchy aliments. The quantities of the last were constantly varying; but those of the former were always the same. This free muriatic acid forms, with the organic elements which have been dissolved in the liquid, digestive fer- mentation. SCHULTZ maintains that the gastric juice is of an alkaline nature, which can be casily proved by experi- ments after a meal. In opposition to his assertion, the first enquirers maintain, that, if the gastric juice is alkaline or neutral, this has been simply caused, either by the absolute or relatively increased formation of mucus, or by the more than ordinary swallowing of saliva. While such cntirely different assertions exists, what are we to think or say of the various cxperi- ments and modes of treatment which have sprung from the one or the other view of the matter that phy- sicians may have taken? May not what is looked upon by one as a remedy, be considered by another as a relative or an absolute poison? Woe to the patient who becomes the apple of discord in such hands! LETTER II. FORMATION AND DISSOLUTION OF MATTER. Other THE blood is ready. It circulates through the veins of the organisation. The enquirer observes, with the mi- croscope, a uniform fluid, in which small bodies roll pretty rapidly after each other. The first we denomi- nate liquid blood, the latter blood-globules. enquirers open the vessels, and examine the blood they have withdrawn. Here are their results: according to them blood consists of-1. Albumen, which is composed of nitrogen, carbon, oxygen, hydrogen, sulphur, and phosphorus. It is said to be formed from vegetable albumen, although this contains less sulphur than animal albumen. 2. Fibrine, which contains more oxygen than the albumen; and, besides, possesses sulphur. Fibrine is supposed to be actually dissolved in the circulating blood, and not to arise from the bursting of the blood-globules. 3. Globulin, which is found in the blood-globules, and is composed similarly to albumen, but is without phosphorus. 4. Caseum (caseïn), which contains more phosphate of lime than any other combination of albumen. 5. Protoxide of proteïn, C 18 8. Hema- which is poor in oxygen, and contains sulphur. 6. Trit- oxyd of proteïn, abounding in nitrogen, but containing no sulphur. 7. Hematin, which contains iron; not how- ever, in the form of the oxide, but in a pure state, and in a soluble condition, which, however, cannot be sepa- rated from globulin. Hematin, free from iron, is a dark brown body, which shows that the colour of the blood is not derived from iron alone. This was formerly be- lieved, and, in consequence of this erroneous view, many destructive modes of treatment arose. toïdin. 9. Fatty matters, such as sebacic alkaline salts. The greatest quantity of fat is contained in the blood- globules. 10. Serolin, a fatty matter, incapable of being converted into soap, which is remarkable, for its amount of oxygen. 11. A fat containing phosphorus. 12. Bile-fat (cholesterin). 13. Grape-sugar. 14. Chloride of sodium, chloride of calcium, carbonates, ordinary phosphates, and sulphates of the alkalies, lime, magnesia, and oxide of iron, partly combined with phosphoric acid. The common phosphate of soda which the blood contains, is owing to its alkaline re-active power. The soda predomi- nates in it by far over the potassa. The phosphates belong chiefly to the blood-globules. Food containing much. albumen increases the fibrine and the albumen of the blood. Partaking largely of salt diminishes the fibrine and the water of the blood, and increases the blood- globules, and the quantity of the different salts con- tained in the blood. Drinks increase but slightly, and for a short time, the water-particles in it. Bread, or any grain noted for the phosphates they contain, increases the phosphates of alkalies in the blood. Herbs diminish the amount of phosphates, but increase the carbonates. The phosphorus which has been obtained 19 is burned down to phosphoric acid. You see from this, that diet has a great influence on the salts of the blood. This proves the falseness of the statement, that the proportions of inorganic matter to the globules and liquid blood are so firmly established, that neither food nor race can possibly alter them. It further follows, that the quantity and combination of the ashes depend on no fixed laws. To all this I add, that sugar is very probably dissolved in the blood; but that it has not yet been proved what becomes of it. Perhaps it serves to form carbonic acid, which is expelled from the body. I have also to remark, that the fat does not solely arise from food, but that it is formed in the organism from substances that are not of a greasy nature; the form- ation itself, however, remains enveloped in obscurity, and it has never been proved whether this fat in the blood is separated as such, or is transformed into sugar. I point out all this to you particularly, that it may assist you to arrive at your own conclusions. Now, let us proceed to the formations which arise from the blood. It is the original sap of all the me- chanism of the body; the original mould of all forms, cells, and fibres. As, however, the pores belonging to the coats of the capillary vessels, do not allow the blood-globules to pass through, so the serum which oozes through them can only be intended to feed the tissues, and is, therefore, the real nourishing fluid of the body. Passing through the capillary vessels, it comes in continual contact with the organisation. The separate organs obtain, through this serum, the particles from which they are composed: as, for instance, the nervous masses, albumen, fat, &c., and cause, in a manner as yet unknown. these 20 homogeneous fluids to assume the intended form, and that, for example, the fibrine of the blood, which waters the muscles, acquires the form of muscular fibres. The secreting glands have the double gift of replenishing themselves, and of sending forth a liquid. During health, more water than albumen, more albumen than salts, and more salts than fats, are perspired through the capillary vessels. All the structures of the body may thus be traced back to the blood. Therefore is the blood the shortest summary expression for the com- position of the healthy body, as regards the quantity, but not the quality of the combining tissues, which last is extremely important for the conclusions drawn from analysis of the blood. The construction of the capillary vessels has a great influence on the above- described swiftuess with which the component parts of the blood leave their path. The directors of the capillary vessels differ from each other, according to the parts of the body they occupy, and form nets, the shapes of which are adapted to their peculiar organs and tissues. The capillary vessels of the brain are very those of the marrow of the bones are very fine wide. The network belonging to the nerves, is com- posed of irregular and clongated meshes. In the lungs these meshes are narrow, and more or less of a rhomboidal form; in the muscular membranes of the intestines, they are regular and at right angles. Here, as in the muscles, the nets are tolerably close. This formation of the capillary vessels, stamps, as it were, the quickness with which the parts composing the blood, penetrate their coats. Science, however, cannot establish that the formation of the different 21 tissues arises from chyle. The creation of the tissues is as yet enveloped in darkest night. : The Here, too, a few words more about some of the parts composing the blood, as we meet them in the tissues the thymus, liver, and kidneys contain much albumen. In the brain, it is found in a coagulated condition. The nerves contain proportionally more. albumen than the brain and spinal marrow. fibrine of the blood contains more nitrogen than the fibrine of the muscles; but the latter is remarkable. for containing much more iron. The middle skin of the aorta possesses caseïn, as also the band of the neck (nack- enband). The globulin of the blood is found unchanged in the crystalline lens of the eye; and on that account it is called the crystalline. The horny formations, the clastic fibres and the gluc-yielding textures, are composed of changed albuminous matters; but they surpass the former in oxygen. And yet the connection between the albumen, and the forms of the tissues arising from it, cannot be given; therefore, the creation itself is still a riddle. Instead of the sebacic acid of the blood, we find in the tissues the corresponding neutral fatty matters; in man, claïn and margarine; in ruminating animals, stearine. The fatty soaps are, therefore, analysed on leaving the capillary vessels, and the sebacic acid combines itself with glycerine, the origin of which is unknown. In life, the fatty matters of the brain and nerves are very closely combined; after death they separate. The cholesterin of the blood returns unaltered to the brain. Besides claïn, margarine, and cholesterin, the brain and the fibrous matter also contain cerebric acid and olcophosphoric acid; the first nitrogen and phosphorus; the last phosphorus, but no 22 nitrogen. The development of the fatty matters of the brain remains entirely unknown. The liver contains sugar, independently of what is received from food. From what ingredients it manufactures it, is unknown. If the nervi vagi be severed, the formation of sugar ceases. If the fourth cavity of the brain is irritated near the olive, it is increased. We have now reached the complete structures, the highest formations of the organism. They must be considered in the narrowest sense, as the vehicles of the peculiar functions of the animals. Here is the inner- most laboratory of creation. You have been told that their formation is utterly unknown to us; let us at least see what is stated about their retrograde formations. In consequence of the never-ceasing activity of life, the slack and worn-out particles separate from the still active and vital formations. Here, in the furnace of the busiest coutinual change of material, the albuminous bodies and fatty matters dwindle away. Creatin, flesh-material, creatinin, flesh-basis, inosic-acid and flesh- acid are transitions through which albumen is converted into urea; they are the first results of solution, and can no longer be employed in the formation of the tissues. Like all particles of dissolution, they can therefore be no longer looked upon as organic. Creatin and creatinin are found in the urine, as well as the fleshy part of the muscles. The albumen that is taken into the body, does not leave it as such; but its elements, such as nitrogen, carbon, hydrogen, oxygen, and sulphur do, and that in the form of urea, sulphuric- acid, and sulphuretted hydrogen. As a product of dissolution, uric acid is found in the spleen, which is, by 23 means of oxygen, afterwards divided into carbonic-acid aud urea. Before the separation occurs, the separating produce must go into the blood, which thus contains carbonic-acid and urea. How these are formed no one can tell. Fat is already partly changed in the blood, without appearing as a former of tissues. According to carefully made calculations, it seems that this is not merely derived from food, but is formed in the organism itself from ingredients which are not even of a fatty nature. From the solution of fat in the blood, it appears that the change of matter already commences in it although the actual mould for the formation of the separating matter is situated in the tissues. It is probable that a solution of sugar has already taken place in the blood, although it is not proved what be- comes of it. The final results of the solution of fat and sugar are carbonic acid and water; as intermediate ones, we have lactic, butyric, acetic, formic, succinic, and oxalic acids. Each of these acids differs from the others in the quantity of oxygen. Spirits of wine be- come acetic acid; this is again turned to carbonic acid and water. Ammonia becomes nitric acid. The last results of the solution of the albuminous bodies are-carbonic acid, water, ammonia, and phosphoric acid, or phosphuretted hydrogen. But here also there are many intermediate stages, besides those already named, such as lucine, tyrosin, sugar of lime, lactic, acetic, butyric, and Valerianic acids. These divisions. may vary very much, as their variety depends on the one or the other exciter, particularly in organic dissolutions, as the mobility of the molecules is then greatest. Con- sequently the divisions of the different forces of affinity may receive many different egresses from the different 24 exciters the degree of heat, pressure of air, humidity, and mechanical motion contributing materially towards this. It is therefore apparent that it is utterly impossible to draw conclusions from the analytical produce of the final results, as to the divisions and intermediate steps which have occurred. If we intend to keep a fast hold of these purely chemical results, which are decidedly inferior to the organic ones, it is clear that we cannot say, from the final products of sugar and fat, whether lactic butyric, acetic, or oxalic acids are or were in the body; nor from those of albumen, if urea, lactic, Valerianic ammonia, or carbonic acids are or were present, and if so, in what degree or gradation. Based on these analyses, we are unable to give any dietetic rules to the healthy, or any mode of treatment to the sick, as this would show the greatest ignorance of the intermediate degrees of solution (Verfalls stufen), and the great changes which may occur in them. For it is assuredly not an indifferent matter to conclude that oxalic acid is in the body when lactic acid only is found, or vice versa. It is also deserving of attention, and even highly so, that through the changes occurring in the blood, we cannot state what part of it devolves upon nutrition, separation, and secretion; and therefore all diagnostics of remedy and disease which are based upon such changes must be entirely rejected; for it is assuredly no trifling matter to know whether nutrition or secretion are operated upon, and this cannot be distinguished by following them. It is also im- portant to observe that we do not know the special origin of the secreted fluids—what part of them arises from the blood, and what from the organs. Experience has not as yet proved whether urine, perspiration, tears, and saliva are 25 merely particles of glands in a liquid state, or the pro- duce of other dissolved organs, or if they are new formations of the blood. We only know that urea is met with in the blood. It is therefore not right to draw direct conclusions from the analyses of these fluids as to the state of the blood, and Pathology, as well as the Materia Medica, which are based upon these, are completely wrong, even in a chemical point of view. The analyses as to quantity, particularly that of urine, are very uncertain, and therefore of but little value. The liquid often decomposes under the hands of the operator. As regards the origin and formation of urea, we are again in the dark, on account of the uncertainty of our knowledge as to the real formation of albumen. We cannot therefore, even on finding it in chemical analyses, draw any inference whatever of its previous conditions. We repeat, that the exhaled carbonate acid and the water may arise from albumen, fat, or sugar, and that in a particular case it is impossible to say from which of them they have sprung; so that analyses do not enable us to decide the point. The internal transform- ation of benzoic acid (which contains no nitrogen) into hippuric acid, containing nitrogen, allows the conclusion that other matters of an azotic nature arise from matter free from nitrogen. This renders the decisions by means of analyses all the more difficult. We cannot even decide on the contents of nitrogenous bodies, and those containing no nitrogen, nor on the various phases of these bodies. All this shows, that we have obtained no result enabling us to determine the forms into which the living organism has brought the organic and inorganic elements, so long as we only know what 26 acids and bases, or organic elements, are contained in it. For who can tell how often an element that entered into the constitution of an organic body appears as a found- ation, or as an acid in the ashes, or as another organic combination? The sulphur and phosphorus of albu- minous combinations, on being burnt to ashes, become sulphuric and phosphoric acids. Often, indeed, it must be left undecided, whether, and in what binary combi- nations, inorganic particles have appeared. Yet, still more difficult is it, if not impossible, to indicate the salts in which the acids and foundations found in the ashes have acted in the organisation, even when it is known with certainty that these acids and foundations, as such, were in it. By red heat, carbonates are analysed, phosphoric acid is partly reduced and evaporated, whereas silicic acid which had been deposited while in a free condition, combines itself with alkalies. It is, therefore, utterly impossible to distribute the acids properly to the bases; and impossible to draw conclusions from analysis of the intermediate phases of the organism, or even of a single one of them in a given case. Analysis, therefore, does not afford the slightest support in drawing sure conclusions from the various chemical transitions which the different matters undergo in the body in the processes of formation and dissolu- tion; and still less of the higher organic life in that inner- most laboratory of nature, the tissues. Consider also that the Process of Life is a constantly moving and ever-changing one. Each breath we draw alters the air in the lungs, and, through the organic process resulting therefrom, venous is changed into arterial blood; the muscles into fleshy matter, and flesh- basis; the muscles of the heart into oxide of urea 27 (Harnoxydull); the tissues of the spleen into oxide of urea and uric acid; the crystalline humour of the eye into urea; in short the composition of brain, nerves, blood, and textures is entirely changed. Consider further, that of these uninterrupted trans- formations, but few have been recognised; that we are ignorant of the links existing between them; and you will easily understand that we cannot draw any in- ferences from these single members in fragments, as regards the entire chain of transitions. You will com- prehend, that, in consequence of the transformations continually going on, even during the time taken up in examination, bodies entirely different from those found have formed themselves. Notwithstanding all this, there are many who draw conclusions from the latter as to the former, and we really do not know whether we should pity their ignorance or brand their arrogance. The great difficulty of examination and the impossibility of drawing inferences from analysis have been felt by the cleverest experimenters, and they have consequently stated the results quietly and simply, with- out arriving at rash conclusions, or making arrogant assertions. I will impart to you here, what NASSE, one of the most famous examiners of the blood, writes about its investigation. The kind of food, and the time of eating must be taken into consideration. The value of the highly appreciated ; We must have a effect of food on the blood cannot be too it is of the very greatest importance. knowledge of the quality of the blood, previous to the introduction of food. The effect caused by bleeding cannot be deducted from the total effect. The effect varies according to the quantity taken away; to the 28 time elapsed since the operation; and to the constitu- tion of the person who has been bled. The result of a second bleeding effected several hours after eating, is very different from what it would have been if the first bleeding had not occurred. It is difficult to profit by the results obtained from various individuals; because the constitutions are often so totally different from each other. In young animals the blood undergoes a re- markable change, according to their age. The food and secretions often vary with the change of the season, and so also does the blood. These alterations are not by any means so established as to be of service in experiments respecting the influence of food on the blood. The method of investigation adopted by ANDRAL and GAVANNET is not quite right, as it is based on the idea that the water in the blood-globules contains as many dissolved salts and albumen as the serum. The color of the blood, in a state of health, depends very much on the condition of breathing immediately before the incision is made; it differs considerably according to whether motion or repose have affected it, or the heart; so that other influences are thereby almost obscured. meat diet give it a darker hue, the formation of carbonic- acid, ammonia, and sulphuretted hydrogen gas bring it nearer to solution. Hunger increases the length of the blood-globules (by 7 per cent.) and the breadth something less (about 5 per cent.). The differences in the aptness of the blood to coagulate are difficult to state. During digestion, in particular from two to four hours after partaking of vegetable or mixed food, the numbers deviate most. coagulates very quickly. Repose and Towards the ninth hour it After having fasted for a 29 period of three days, it takes about three and a half minutes more to coagulate. Animal food always caused a quicker coagulation of the blood, than vegetable diet; the former in one and a half, the latter in two minutes. The blood, after animal food, separates more serum in the sixth hour, than if vegetable food had been taken; in the eighth hour there remains no difference. The seasons have a marked influence on the specific gravity of the blood. In winter it contains less water than in summer, and particularly than in autumn. The firm, fibrous, component parts of the blood almost correspond with its specific gravity. Meat diet causes the fibrous part to decrease until the eighth hour; it then increases anew. The proportion of the salts diminishes accord- ing to the time of digestion, which is another proof that the proportion of organic to inorganic matter is not always the same. Under such circumstances, pro- found examiners, in analysing the blood, duly consider all these facts, and take care not to draw conclusions from them, as to the state of the blood which circulates through the organism, well-knowing that it is im- possible to do so. None, but the ignorant and the vain rush into the arena of science with such attempts, and crush their heads against its iron defences; for their rash conclusions burst and explode at the mere breath of learning, which annihilates all untruths as if they were mere soap-bubbles. For the many changes of the blood which occur during life cannot be plaeed within the narrow frame of an increase or diminution of the fibrine, albumen, or The picture that is to be painted must contain all the changes of the nerves, the blood, and the tissues; and water. 30 thus only can life be faithfully and undividedly portrayed. Besides, analyses have been gathered from blood which had been abstracted from the veins; from blood with- drawn from its organic association with the nerves, the tissues, and their combined influences; and placed under the entirely different influences of light, atmo- spheric pressure, electricity, and heat. When every breath which is drawn causes the greatest change in the circulating blood of the organism, it is clear that the withdrawn action of nerves and tissues, that is, of combined organism on the one side; and, on the other, the new influence of light, atmosphere, and heat, must instantaneously cause still greater alterations; that, therefore, the blood taken out of the body, no longer resembles that which circulates in it, and that its analysis, as an analysis of dead blood, cannot possibly be a rule or standard, for the living blood of the organism. Far more organic is the theory of SCHULTZ. He speaks of having made the living organised elements of form, with their alternate effect and self-excitement, the object of research in the blood, the proportion of the excitement of the blood-globules as plasma in the arterial, venous, and neobitic blood. Unfortunately his results have also been obtained from blood abstracted from the veins, and, as we have already proved, are without value. Life can only be measured by itself. Thus, those results only which are gathered from the living circulating blood, when undisturbed in its organic unity, can give rules for it. Let me here add a few remarks on the statistics of the change of matter. With the full-grown it is such that receipt and expenditure balance each other. The 31 albuminous bodies which have gradually changed into horny matter, uric acid, urea, and phosphates, leave the body in the form of the hair which falls off, expelled epi- thelium, mucus, and urine. The fat-formers and fatty matters that have been changed to carbonic acid and water, are evaporated through the pores of the skin, and exhaled by the lungs. The inorganic component parts are withdrawn from the body through urine, the excre- ments, perspiration, slime, and horny formations. The proportion of the perceptible to the imperceptible secre- tions is 65: 3:45. Of the 65 which escape through the skin and lungs, 348 belong to water, and 302 to car- bonic acid. The change of matter goes on much quicker in persons of regular habits, than in those who fast. A hard-working man changes, in 20 or 30 days. the greater part of the matter composing his body. It is worthy of notice that the secreting organs, par- ticularly in illness, change their functions, so that the secreted productions of the skin are expelled by the kidneys, and those of the kidneys by the lungs. Thus has it been discovered, that in inflammation of the lungs, from the commencement of hepatisation until the beginning of absorption, all the fixed combinations of chlorine were totally wanting in urine, while they were greatly increased in expectoration. It is, therefore, necessary to calculate all secreted productions, if we want to know the general expenditure; as the particular secretions continually vary, and those that have not been calculated, cannot be judged from the results of others. It is superfluous to say how very difficult it is to calculate the perceptible and imper- ceptible secretions, even of the healthy body. Therefore 32 with most sick persons it is entirely impossible. At best, may we succeed in reckoning the perceptible at one-third of the whole. This does not enable us to draw conclusions concerning the quality and quantity of the remaining two-thirds. It is therefore impossible in most cases to obtain from calculations of the secre- tions, the least approximate knowledge of the final results arising from the change of matter; and yet there are persons who vainly fancy that they can draw inferences from such analyses, of the process of life itself, when in reality they have only arrived at the extreme boundaries of the chemical and physical pro- cesses which accompany it. They have only got hold of the worthless tools, the worn-out means which were employed by the organism to attain its highest aim, the formation of the textures and structures-the real pro- ductions of life. They are not able, even with these, to decide on the few already known chemical changes of matter. The very result arising from their inferences, is only valid for a single instant; as restless life in its ever-ceaseless, ever-continuous receipts, changes, and secretions, necessarily alters it incessantly. It is besides a fact, that in the organisation, one ingredient can rc- place the other, one basis the other, and one acid the other; that the chemical combination of organic struc- tures, within certain limits, may vary considerably, with- out lessening the excitement of life in the least degree; and, finally, that the chemical mixture of the blood is the same in its various dyscratic conditions, such as melanous, bilious, apeptic, anaplasmatic, and paralytic. Thus chemical analyses do not discover, but rather con- ceal its real nature; and through presumptuous know- ledge render cure impossible. 33 But they cry out: "From the productions you may draw conclusions respecting the producer!" As if the task of life was merely these offals of the body: tissues, formations of structures, and their functions, thought, move- ments, action-those are the productions of life; while urine, excrements, sweat and exhaled air are but the worn- out materials, forming in chemical transition an unbroken chain, whereof but few links are known, and even these few cannot be explained by the results of the last which were used for analyses. Would you not think it very foolish, if any one de- clared the ashes of a picture to be the production of the painter; and particularly if he described, from them his colours, outlines, expression, and style? But not a whit less foolish is it, to wish to explain the process of life itself, and its manifold, ever-varying manifestations, from the mere analyses of the secretions. And, there- fore, LIEBIG says rightly: "It is certain that many of the effects which we perceive in the living body are derived from chemico-physical causes; but people go too far in concluding from this, that all active forces in the body, are identical with it." I have been purposely more diffuse and explicit with the changes of matter, in order to show you quite clearly how utterly untenable its present theories are. This is all the more necessary, as the preachers of these doctrines hold themselves to be the sole masters of learning, and proclaim loudly that he only is a phy- sician who looks upon life as a mere chemico-physical process. You know how the Pythia, seated on her Tripod, or three-footed stool, excited by subterra- nean vapours, gave forth the most hazardous and D 34 ridiculous oracles. Be not then astonished if these pro- fessors, seated on their nameless chairs, thickly clouded in the intoxicating vapors of matter, writhe with con- tortions in the midst of chemico-physical productions. But as to their oracles, let them endeavour to find a more credulous ear than ours! LETTER III. THE NERVES. RETROSPECT. NEXT to the blood, the nervous system is of the highest importance in the organism. It extends through the actions and material conditions of the body. Although itself dependent upon matter, it is at the same time very EXACTING as to its quality. How often has it not been regarded as life's sole foundation; and how often have not doctrines of life and of cure been grounded on it! Let us see if people were justified in so doing. The organic action of the nerves refers to the touch, sensation, motion, and nourishment. How it stands with the nerves operating on the latter we do not yet know with any degree of certainty. Some kind of stimulation awakens the nervous action; but the process in the nerves which follows this stimulation is not known. Many affirm it to be a movement of the molecules,-a different group- ing of them, so that the nerves transmitted material changes to the brain and spinal marrow. But no one ever yet saw those molecules, or observed their different groupings. Therefore, all these empty phrases of 36 molecules and molecular power are valueless, and do not furnish the slightest insight into the existence of the act. The impulse, or excitation, which occasions the activity of the nerves, in many instances, is unknown, there occurring in the organism so many things which we do not at once perceive, and which we cannot positively trace to their origin. Thus, the investigation of the functions of the cerebral nerves is very difficult, as the experiments are of the most dangerous nature. This is the reason why the greatest doubt prevails as to that most important of all organs-the brain. Nor is it yet scientifically explained, whence it comes, that pain is felt where the pain-causing impression was made, as perception must first take place in the central organs; the brain or the spinal marrow. The stimu- lants themselves are supposed to be of such a nature, that all the nerves are not affected by them. Their extraordinary sensitiveness, particularly those of the nerves of motion, to galvanic stimulation, is very in- teresting. In disease, there is often a really astonishing sensibility both of the nerves of sensation and of motion. Still, we do not know the conditions under which a nerve is brought to such excitable reaction. Of late, certain parts of the nerves have been discovered which are less sensible to the same stimulant than others. The sensitiveness of the nerves is annihilated, or, at all events, very much diminished by acids, alkalies, nar- cotics, and continuous irritation. The visible result arising from the stimulation of the nervous system is called effect. This differs in quality in the various. kinds of nerves; but it may also differ in quality in the Thus, the pricking of a needle is felt as same nerves. 37 such; but it can also cause pain in the same place. The heaviness of a weight may be guessed at, from holding it in the hand; a heavier one causes pain; a still heavier one, produces a prickling sensation. The effects are positive when their appearance is visible; and negative, if not. The positive effect of stimulating the nerves of motion, would be motion throughout; that of the nerves of sensation, a perception of pleasure or dis- pleasure; that of the sensual, sensations; each assuming its destined form, the optic nerve, in seeing, etc., etc. The quality which causes these transformations in a fixed way, is called nervous energy. This is not caused by the stimulation of the nerves, as that of the most diversified kind may produce motion, sight, etc. Notwith- standing all this, stimulants are not to be looked upon indifferently, as the sensibility of the nerves to them varies considerably. Science cannot decide whether the nervous energy originates with the nerve, or with the central organs. All long-continued stimulation works finally in arresting the effect. This, however, can be renewed by a different stimulant. The negative effects either follow the positive ones, or they are primary. The strength of the effect depends on the quantity and quality of the stimulant; on the susceptibility of single nerves always, and on the characteristic sensibility of all the nerves under certain circumstances. Habit lessens the effect. The sensi- bility of the nerves varies considerably in different individuals. Reflex movements, or such as occur without the will or consciousness, often follow bleeding, hunger, the use of mercury, and weakening remedies as well as some narcotics; and this is, unfortunately, 38 not sufficiently considered by many, while carrying out their barbarous modes of treatment. The objects of taste must become dissolved before they can be perceived; but it is not known what pro- perties must combine or unite to make a body acquire taste. The nature of taste is not at all understood. EDWARD PFLÜGER, in a work entitled, "The Sensorial Functions of the Spinal Marrow of Vertebrate Animals," threatens to effect a complete revolution in the theory of the above-mentioned reflex movements. He insists that we should be guided by fixed principles only; that to come to certain and truthful conclusions, we should never employ problematic premises; but facts and facts only. After proving that the explan- nations of REIL, KÖLLIKER, and JOHANNES MÜLLER are unfounded, as regards the radiations (or co-sensations) of the nerves, EDWARD PFLÜGER continues as follows:- Although we are compelled to acknowledge that we are ignorant of the manner in which these radiations originate; yet we are not, on the other hand, prevented from studying the laws which govern their appearance." This remark, together with the one previously ex- pressed, that facts only justify conclusions, cannot be too often repeated; and their strictest practice and observance can never be sufficiently recommended. (6 I call your attention to the four great laws which Edward Pflüger establishes with so much lucidity; but as it would lead too far to detail them here, you must rest satisfied with the result. According to him, tonic and clonic cramps, and epilepsies are reflex movements; on the contrary, the movements of decapitated and sleeping persons, and those caused by wiping away the acid from beheaded frogs in opposition to the present 39 As it is theory are not reflex movements, but are acts resulting from sensation, consciousness, and the will. with the reflex movements, so is it also radiations. with the It is, further, important, that according to his view, the fibres of the nerves of motion, as well as of those of sensation, terminate in the spinal marrow, and do not ascend to the brain, as was formerly affirmed. These new results show that most of the biologies and modes of cure, which were founded upon the former view of reflex movements, are false, and strikingly demonstrate how difficult as well as fatal it is to base new theories of life, or cure, on any new physiological result. I have purposely directed your attention to a few only of the most important points occurring in the theory of the nervous system. They will amply prove to you, that here, as in the theory of the blood, we have but little of what is certain, and plenty of what is vague, contradic- tory, or entirely hidden. And now a few words about organic heat, a subject of the highest importance, as without heat life must cease. Mark what a thoughtful physiologist says on the sub- ject:-"To be able to state how much heat is generated, we ought not merely to know the amount of oxygen received into the body, and the quantity of carbonic- acid, hydrogen, and urea secreted, but also from what matter the carbonic-acid, hydrogen, and urea were derived; how many and what kind of salts a body has formed; how much water was condensed; and how much carbonic-acid was dissolved in the fluids of the body. We ought to know what heat the body is deprived of by radiation, evaporation, change of air, and solution." We see here one of the many instances in which the 40 change of life cannot be limited by mere figures. It belongs to the real knowledge of the doctrine of life to look beyond the range of such obstacles. No playing or risking with mathematical rules can be permitted. The theory of life must contain a faithful account of the appearances of flickering life. It is a compounded formula of ever-varying magnitudes, so that the degree of heat never keeps pace with any of the occurrences which compose and regulate matter. It is impossible to express more clearly and distinctly the insufficiency of the explanations of organic incidents furnished by chemical or physical processes, and I there- fore abstain from any further remarks. If you cast a look on what you have gleaned from physiology, up to the present time, you will soon find that SCHULZ was right in asserting that physiology threatened to become a natural philosophy and chemistry of life, in which all organic life must perish. For what have you found, in reality, in the elaborate and bepraised theory of the change of matter, but the results arising from the dismemberment of the required conditions of life, and of life's offal? Has even a single organic act of life been explained? Is it not impossible, in many instances, to explain even the formation and change of these mere refuses of life? It is true, that life requires bodies endowed with certain chemical and physical powers; but it uses them as a means, as work-tools, and subjugates them to its vital organic laws, and it is only through this subjection, through this abolition of chemistry and of mechanism, that life becomes possible. If the chemical and physical powers gain ground death ensues. Truly, we know not where this subjuga- 41 tion, this changing of the chemico-physical forces into. vital ones takes place. For life, as we now begin to understand it, is but a participating power, continually advancing, and taking fresh root from one unity to another. Motion called into action confines itself to a series of excitable matter. However, not matter, but the vehicle of life is the peculiarity; the motion of matter, life itself, is it; therefore the body is not the unity, but the motion, which is shared and sharing. For it is not the form, the through-cellular-construction, for a moment fixed matter, that is being; but the inner onward movement which causes plastic combinations and which is ever creating more perfect and more energetic forms, in proportion as the conditions for extending vital motion become more and more favour- able. Yet even as regards this fixed form, we have no knowledge of its internal condition, of the grouping of its elements, or of the assembling of its smallest particles. Consequently, Materialists cannot arrive at any doctrine of organic life. Even chemistry has not been able to compose from chemical elements a single one of the primitive bodies, those first-born of the organisation, fibrine, albumen, and starch; nor have physics had the power of forcing any one of these, when given, into cellular formation. They always refer to the formation of urea, in a chemical way. But urea, that cyanate of ammonia, is but offal of the body, and has no longer the power of organising, and the organism cannot be explained from its offals, urine and excrements. The atomic proportions of the same elements, do not prove the absolute similarity of the body composed of these elements. Here PASTEUR's clever experiments on isomeric bodies, by light, should be noticed. Thus was 42 it formerly believed that two malic acids were alike, the one being obtained from aspartic acid, and the other from fumarate of ammonia (erdrauch saurem ammo- niak), and both containing the same proportions of carbon, hydrogen and oxygen, until the application of light on the acids, proved that the first deviates the polar ray of light, and the last does not, showing thereby a different placing of the minutest particles. It is almost the same with the two acids into which grape acid may be divided. They both contain the same proportional mixture and crystalline form; but the one deviates the polar beam to the right, and the other to the left. Before, therefore, the perfect equality of the cyanate of ammonia, and of the urea, ob- tained by LIEBIG and WÖHLER, can be admitted, the above. experiments must be made on them. But even sup- posing that a perfect equality existed between them, still this would have been of no use for organic life, and consequently nothing very important would have been proved. For all this appertains only to what is chemical and physical. He who follows up and attentively observes organic life, soon discovers that chemical and physical processes only accompany, but never represent it in its actual being, nor do they contain its primitive cause; this is only to be found in a participating movement, which of itself de- velops organic life according to fixed laws, and only uses chemical and physical bodies as subordinate agents. Therefore, if we could even command light, heat and atmospheric pressure, in the same degree that we do the proportional weights of matter, still we should be unable to produce organized forms, as there is no proof that these forms originate with them; and werc 43 success to crown this effort, no organic life would be created thereby, as form and liquid are but minor com- ponent parts of life, which uses them merely as vehicles; whereas participated movement, the very cause of life, lies far beyond the reach of all physical observation. Highly important, for an appreciation of the results hitherto obtained by physiology, is the fact, that the existing anatomical structure has always been made the basis of the various functions of life; whereas life itself first forms this structure; thus, when complete, it cannot be considered as the cause, but as the effect of life. This must, of course, give an entirely contrary meaning to the views and theories which have hitherto been received. Thus, the completed structure of the heart is only developed by circulation; for, in all em- bryos, the motion of heart and blood exists, before these anatomical conditions have completed themselves. The perfected structure cannot, therefore, be the first and sole cause of circulation; and, consequently, the theory of the circulation of the blood, as explained by suction and pump-power, is false. The same may be said of the secretions, as with them also the completed formation of the glands is supposed, although they are only formed by life. It is not suffi- cient to be acquainted with the finished form, but the organic proceedings of life must also be recognised and understood; also, how the minutest particles of form develop themselves; how the internal tissues arise, and how the work-tools originate. Thus only can an idea of organic creation be acquired. But, unfortu- nately, not only has this not been done, but most of the results have been gathered, outside of the 44 organism, from experiments on highly-excited and mutilated animals. Nothing, however, can justify per- sons in drawing conclusions from experiments beyond the organism, as to what happens therein; for, as I have before explained, the conditions are entirely different. Neither can the inferences drawn from experiments on animals be applied to the human body; because the organic unity has been annihilated in those experi- mented upon; and also because there exists such differ- ence between man and animals, that it would be more than presumptuous to draw from the latter, uncon- ditional rules for the former. We do not mean to say by this, that experiments on animals, as throwing light thereon, may not be of the greatest use. They really are so, and they should be continued. They are, how- ever, often made in such a manner, that a wit ventured to say "Physiology resembles the grimaces of a frog which is being stretched on the rack." :- There is a good deal of truth in this remark, as you will yourself find, on reading the descriptions of these experiments; but the dismemberment of the organic unity, to which we have before alluded, shakes con- siderably the solidity of their results with regard to the organism. In the experiments made on the blood, you will find that its alterations only have been noted down; without the slightest allusion to the simultaneous changes of nervous and textural life. The same occurs in their experiments on the nerves or tissues, wherein the vitality of the blood is not considered. And yet a true organic insight can only be obtained from the undis- turbed and indivisible organic unity, in its simultaneous blood, nervous and textural existence, with their combined 45 functions. Physiology is, therefore, incomplete in all respects, both as regards quantity and quality. When Virchow, therefore, maintains that the various pro- cesses of life exist as long as life lasts; that they exist in the same manner and number in the healthy, as in the diseased organism, with this difference, that their manifestation varies, as the same law of nature reveals itself in different forms, according to the conditions under which it appears; then, indeed, to verify such an assertion, the most complete knowledge of all appear- ances which take place in health, as well as in illness, are absolutely required. Thus, only, is it at all possible to compare the manifestations of the healthy body, with the one suffering from disease, and to decide on their equality or disparity. But the deficiency of our knowledge of the appearances in healthy life, is proved to you by every page of physiology. Therefore, physiology, the theory of life in its healthy state, cannot be unconditionally applied to the diseased conditions of the body; because the proof of the equality of both in their inner lawfulness is actually wanting as yet; but we are obliged, by the present state of things, if we would be but simply just towards the results that have been obtained, to look at the healthy and diseased con- ditions separately, and to study them thoroughly, so as to be able to read the laws from the appearances; without, however, making the healthy state at any time a standard for the diseased, or the diseased condition a standard for the healthy one. But they may explain each other mutually, an enlightened comparison of both is therefore not only serviceable, but even necessary. From all this, it is evident that physiologists have, at most, but crossed the portals of life; without a 46 single one of them ever having been able to penetrate its sanctuary. The results of all their investigations terminate principally in chemical and physical pro- cesses, and description of form. There is not the slightest trace of any organic theory of life, which represents it as indivisible uniformly in blood, nerves and textural life, with all its present and future reve- lations, its conditions, and the accompanying chemical and physical processes and throwings-off. The foundation stone of such an edifice has not even been laid; although others fancy they already see its cupola ! Mere preparations are made, and mere chemical and have been furnished. But life itself is neither in- physical materials voked, nor explained by it. Life derides paltry mathematical problems, because absolute rules for it can never be invented. It imperiously requires, to be truly and faithfully portrayed in all its various reve- lations, its development and its growth. We must ar- range and classify these revelations, with minds entirely clear and free from prejudice, and going from the external to the internal, endeavour to unite them on a mutual basis; always allowing ourselves to be guided by the hand which unitive organic life itself presents to us, and never by facts derived from extraneous sources; utterly excluding every hypothesis, and only making use, in the most prudent and careful manner, of the results which have been obtained of the dismemberment of the organic unity. In this way, only, can the real organic laws be dis- covered. For life can only be measured through itself, and the truer we draw the picture in the manner afore described, the more effulgently its laws will appear. With this, the acme of natural Philosophy will be attained, and physiology will have become a real biology, an indisputable truth. LETTER IV. PATHOLOGY. You have seen that physiology is yet struggling with the very beginnings, that it furnishes us with little or no explanation throwing light on the organic processes of healthy life, and, consequently, is at best but of relative value in explaining diseased conditions. Does pathology offer us more? This question is all the more important for us, as it refers directly to the diseased condition, to the object of cure. There are two especial lines of direction or modes pointed out in this doctrine-the material and the dynamical. The first already exists in the theory of qualities of the ancients. They indulged in the wide- spread, and almost universal, belief, that the organism was composed of the four elements of humidity, dryness, heat, and cold. The harmonious blending of these con- stituted health; if it was disturbed disease at once ensued. The harmony could only be restored by separating and expelling the cause of disease. This separation was called the crisis. Instead of these four elements, the moderns have set up the chemical com- ponent parts of matter, on the proportionate admixture 48 of which healthy life depends, and in which any irregu- larity whatever engenders disease. Some seek these irregularities in the liquid parts, in the blood-these are the humoral-pathologists; others search for them in the solid parts, nerves and muscles-and these are the solido-pathologists. Setting aside this division of solids and fluids, more recent materialists maintain that disease only arises. from disturbances occurring in the composition of mat- ter of both the liquid and the solid parts. In opposition to this material view, there is the dynamical one of GLISSON and STAHL, according to which the soul is the only originator of entire organic life, and therefore, also of its diseased conditions; and itself, independent of matter, forms or constructs its body of it. BROWN, in his "Theory of Excitement," developed this spiritual system in the highest possible degrce. BROUSSAIS's theory of local irritation, and RASORI's theory of counter-irrita- tion, are but modifications of BROWN's work. Next to these views, the School of Natural Philosophy attempts. to explain and elucidate the diseased conditions, by com- parisons with the inferior organisms, and the degrees of organisation. Others attribute to disease a separate. existence, which from a germ develops and spreads itself through the whole organism, and parasitically preys and thrives on the animal and human body. And, again, others will have the diseased state explained only by its own products, and seek to make pathological anatomy the very ground-work of pathology. Physiological School insists that pathology can be traced back to physiology. The laws of the healthy conditions are considered by it to be the same as those which pre- vail in disease, only revealing themselves under The 49 abnormal conditions. To maintain such an assertion, the most intimate knowledge of all the laws of healthy and diseased life is required, in order to be able to decide with certainty on their equality or disparity. This knowledge is still wanting, as I stated to you before. All the views and opinions which I have communicated to you, in mere sketches, assert themselves in existing pathology. Aye, more than that, we sometimes find the most conflicting views in perfect unison with each other. Here, as in physiology, the diseased organic process of life is again represented by descriptions of form, chemistry, and physics. As physiology explains the healthy, so does pathology endeavour to explain the diseased, states, from the conditions of life, and from life's offals, and from blood and muscles, which are lifeless, or at all events deprived of their usual associations or accompaniments, but with the same unfortunate result, because, for the reasons which have been already given, the organic process of life can never be thus explained. Equally foolish is it to attempt an explanation of the process of disease, by means of pathological results, as they are the simple products, and not the cause of the diseased conditions, and the body in life, though affected by disease, can never be compared to that which is actually dead. Moreover, it must not be lost sight of, that many of these conditions arise only after dissolution, as the death-polypus which is found in the heart and the aorta, the serous effusions of the brain after apoplexy, and the effusions occurring in many of the cerebral diseases of children. Remarkably instructive in this respect is the discovery of Professor RITGEN, while dis- secting the bodies of patients who had died of malignant puerperal fever; for previously to this, the uterus was E 50 always found in a state of decomposition, and looked upon as the cause of the disease. When, immediately after death, he examined the womb by the speculum, he did not find the slightest change in the organ. An hour later, a softening had taken place, and a whitish colour was perceptible, and with every ensuing quarter of an hour, this corruption increased to such an extent that, on dissecting the body shortly afterwards, that putrefaction was clearly discern- ible, which other observers had also found, and had erroneously believed to have been the cause of death.. Such discoveries make us naturally and justly suspicious with regard to many of the statements of pathological anatomy, and there can be no doubt whatever, but that their intrinsic value has been excessively over-rated. Would that medical men, instead of looking, as it were, to the mere refuses of life, would at length confine themselves to the examination and representation of the diseased con- ditions in their organic development. Thus they would be able to understand the organic laws, instead of attempting, as they now do, to comprehend them by strange definitions of qualities, chemical materials, living individualities, and spiritual powers. Would, also, that care were taken not to shiver organic unity to atoms, by dividing and subdividing it, or by making any single or individual part, whether the blood or the nervous system, the sole vehicle of the organic process; for it can only be thoroughly understood by a per- fect conception blending sanguineous, nervous and textural, life together, in its living activity and never-ceasing trans- formations! All pathological systems have hitherto been derived from chemistry, physics, old elementary theories, or from physiology; and too often do they take but a one- 51 sided view of nervous or sanguineous life, instead of de- veloping the laws, for the diseased conditions, in organic unity from themselves. As long as the diseased organism is ransacked in its products of solution, as inorganic chem- istry, the true organic insight will be lost. Every man forms his own opinion of disease, and of its nearest proximate cause, from the system which he follows, and directs his treatment accordingly. Life is thus left to the discretion of the doctor, or to the chance whether he hits on the right remedy or not; and he too often destroys or- ganic life, the very antipodes of chemistry, by his inorganic chemico-physical opinions. For the verifica- tion of my assertion, you have only to look at any monograph on any disease. By way of example, I will quote here to you the different opinions about the nature of delirium tremens, a disease which medical men have known for a very long period, and which they have most assuredly had time enough to study over and over again. ARMSTRONG derives delirium tremens from venous congestion in the brain and liver, the result of increased activity of the heart and arteries, caused by some previous irritation. KLOPP, from derangement of the digestive organs. SANDWITH, from venous and abdominal con- gestions. STAUGHTON, from inflammation of the stomach. PLAYFAIR, from a diseased state of the liver, and secre- tions of the intestines. GÖDEN, seeks the seat of disease in the plexus solaris and coeliacus, considering the etherial immaterial affection of the brain, to be merely sympathetic. GÜNTHER, supposes it to be either an idiopathic affection of the brain, caused by metastatic deposits, or a sympathetic affection of the brain, origi- nating in gastric irritation. TÖPKEN, takes it for a 52 sympathetic irritation of the cerebral system, arising from the plexus cœliacus. According to PERRY, the nature of this disease consists of a feverish, inflamma- tory affection of nearly the whole of the brain. SUTTON, fancies that it exists in a peculiar irritation of the brain, nearly akin to phrenzy. ANDREÄ considers it a state of real inflammation. BISCHOFF thinks it an asthenic inflammation of the brain. According to HARLESS, it is a superficial erysipelatous cerebral inflammation, an asthenic paraphlogosis of the cerebral membranes and the brain itself. BLAKE ascribes it to an indirect weakness of nervous power, consequent on a diseased and increased activity of the nerves and brain. HUFE- LAND takes the disease for a delirium nervosum, result- ing from passiveness. WASSERFUHR believes in a material transition of alcohol into the blood, from which drunkenness arises, and from which, when the alcohol can no longer be assimilated, a lasting affection of the brain ensues. According to SPÄTH, it originates in a disturbed equilibrium between the brain and the nervous system. William STOKES believes in two principal forms of it: one, from a want of excitation, as in casual fevers, when a low diet has been ordered; and another, from over-excitement, for which he recommends leeches and iced-water. SILBERGUNDI defines the disease, as arising from a progressive alcoholisation of the brain and nervous system; from a direct increase of the sensible factor of life representing expansion; with a direct decrease (passiveness) of irritability, the vehicle of the life-agent, representing contraction, and, which becomes permanent, and rears this particular form of disease, if any other invading power affects the alcoholised organism and forces it to such reaction, that a sound sleep 53 can no longer restore the balance, as it often did before. You see that there is no lack of varying opinions, and yet, must you say, there can be but a single right one, and that right one is certainly not among those which have been stated. You will find the same excessive variety of contradictory opinions, in the explanations given of the gout, of rheumatism, fever, hip-disease, cholera, &c. &c. Every one forms, according to the know- ledge he possesses, or the education which he has received, a personal opinion of the nature of the internal process, and of the so-called nearest or original cause, and he then assails with all possible remedies the Goblin, conjured up by his own imagination, and which he has installed in the inner- most recesses of the diseased organism. That the most varied and contradictory modes of treatment, of the same disease, are resorted to under such circumstances, may easily be imagined, and is not to be wondered at. The unprofessional doings of this kind, are not inaptly described in the following verse:— “Disease and nature fight, the doctor, self-assured, Strikes between both; if his heavy staff Knocks down disease, you are soon cured; But if stout nature's felled, you sink into the grave.' Yes! in presence of so many existing contradictory opinions, it is real, hap-hazard, striking between! How can we otherwise designate a treatment that often em- ploys the most dangerous and hazardous remedies? And yet, such proceedings are qualified as scientific. Nay, *Im Kampf sieht er Natur und Krankheit tritt hinzu, Und schlägt dazwischen ;-trifft sein Stab' Die Krankheit, so genesest du Und trifft er die Natur so wanderst du ins Grab. 54 the rage for indicating the origin of a disease, and for composing a diagnosis, is carried to such a pitch, that one of the highest authorities encouraged the medical students of his class, by saying :-" It is better to die with a diagnosis, than to recover from illness without one." We have a right to be astonished, when such a mode of proceeding, as this, is called science. Do we gather a single grain of real knowledge from it? In almost every instance, is not the doctor's imaginary creation forced upon nature? Really, if anything ever contributed powerfully to the propagation of error, de- ception, and wrong, it is this witless hunting after the establishing of the original cause. Such a course leads not to real knowledge, but to error, which is the parent of folly and delusion. The sad consequences to humanity which spring from this are innumerable. I will only furnish you with a single example. On the 31st December, 1829, Professor Dr. Grossi, the ornament, the pride, and the pillar of strength of the University of Munich, died there. The best physicians of that capital attended him. All decidedly agreed that he was suffering from inflamma- tion of the lungs. In five days they took ninety-nine ounces of blood from him, and applied a number of leeches besides. The last day the patient requested them to let him alone, that he might die in peace. At the same time he emphatically declared that he was dying from want of blood. The dissection which followed proved clearly that he had never suffered from inflammation of the lungs. The indignant horror of his friends and relations provoked a long paper warfare, during which more printing ink was wasted, as to quantity, than the blood which had been taken 55 from the unfortunate Professor; but not one of these attacked physicians could defend himself success- fully. When this happens amongst the very best doctors, in reference to a disorder of the lungs, what can we then expect from less educated medical men, in diseases of a more obscure nature? This unsettled state, this substitution of supposition for knowledge, on the part of medical men, has been sharply and satirically criticised by GIRTANNER, as follows:-" Every doctor has a right to follow his own ideas. Where no knowledge exists, where all is mere guess-work, one supposition is certainly worth as much as another. When two doctors meet, in consultation, at the bedside of a patient, who is not dangerously ill, it often happens, as is the case with the fortune-tellers in Rome, that they have great difficulty in refraining from laughter while looking at each other." The impossibility of inward diagnostics has been already acknowledged and proclaimed by celebrated practitioners. REIL, whose work on fever is classical, and who, there- fore, may well give an opinion upon it, says :-" We only take note of the outward causes of disease, and some- times not even of these; and of their final sensual workings, viz., the visible symptoms of disease. But we cannot form the slightest idea of all that is intermediate, nor of the nume- rous changes occurring in the body between irritation and the appearance of the various symptoms of disease, which indicate the unnatural condition of the body, and the derange- ment of its functions." He adds:-"Both from what we have said about the nature of diseases attributed to a faulty vital power, and their proximate cause, and from the different opinions which have always been entertained of fevers, it is evident that we are ignorant of 56 their nature, and that the treatment of them is nothing else but downright empiricism. Numberless suppositions about the nature of fevers have been registered in the annals of medicine, and have died away as soon as they sprung up. Genius and mediocrity have alike failed in the endeavour to undo this Gordian-knot. The very multiplicity and diversity of the opinions given is the infallible proof that the nature of the subject is not yet understood. For as soon as the truth is fairly established, certainty takes the place of supposition, with every man of common sense." This quotation from REIL shows that the substition of the words error, folly, and supposition, for that of science, would be more characteristic. CHOULART is more general, and more explicit still; he expresses himself thus :-"This uncertainty in the ex- planation and treatment of inward disease results from an over-estimation of our mental faculties in presuming to comprehend, not only the unknown and internal process of disease, but in making this very inscrutable- ness the ground and foundation of our medical theories. We are satisfied with images, and mock explanations of every new cause of disease, and base our system of patho- logical therapeutics upon them; when every eruption of the skin, every affection of the nerves, every fever, should teach us, that it is easier to get a glimpse of almost any- thing in the world than of those inward proceedings which regulate the course of disease. The ancients went more modestly and more success- fully to work, and gave proof of the sound common sense for which they were so remarkable, by judging a disease only from what was perceptible, examining it from every possible point of view, with perfectly unpre- 57 judiced minds, and therefore, although possessing infinitely less knowledge than ourselves, they were not unsuccessful as medical practitioners. Nothing is recognisable in disease; but its remote cause, and the totality of its symptoms. The next cause, which is the middle link that connects both, is undiscernible to us. And yet we have taken that which is the most uncertain of all, in the whole extent of medical science, our supposed knowledge of the proximate cause, for our foundation, and, theoretically, allow aetiology and semiotics, as lateral branches, to grow from it; pruning and plying them, so as to suit the pathological basis. We would diffuse light out of darkness; but it will not shine. We have built our temple on the sands of supposition; and it sways like a reed to the wind. We have no real useful knowledge of diseases. We know them only as they might be, and could be, and not as they actually are. The heavy fetters of a system prevent and impede a free exercise of medical talent, and render all artistical use of it impossible. The science of practical medicine does not advancc a single step, notwithstanding the highly developed state of anato- mical physiological knowledge; because we have entirely lost sight of the fact, that it is a free and perfectly inde- pendent science, which may gather information from other doctrines, but must not depend upon them. Again,” he says, “the inward cause of disease is as undis- cernible, as the cause of life itself, and inasmuch as sound physiology is simply satisfied wlth comprehending the laws of healthy life, taking the rest for granted; so also real practical medicine requires no elucidation of the inward cause; but its great aim is a thorough comprehen- sion of the laws of disease and recovery." And, in another (C 58 part of his work, he says, "The classification of diseases into species and sorts, as naturalists do in their science, has always been detrimental to pathology. It induces us to regard that, which is ever moving and changing, as something permanently fixed; those, which are un- folding themselves in endless degress of diversity, as on a par with each other; and it presents, as suited to the comprehension of the student, lines of demarcation, which can scarcely be distinguished and understood by the master himself. It is praised for being a model of method and order; and it is "confusion worse con- founded; for it separates affinities, and unites antipathics. It is lauded for the light it affords; and the shadows of its walls hide from us the nature of things. We seek in it the foundation of rational practice; and its catalogue of names leads to the dullest routine. Instead of this borrowed framework, which may be very suitable to other sciences let us endeavour to establish a sure central point for pathology, around which the constant and fixed forms, and, after them, the variable and more distant ones may be grouped. To this, let us add the scale of duration in the various forms of disease; it is a very varying one, and of the highest importance." With these observations of CHOULART, the materialists, who, since then, have taken up a prominent position, do not agree. And yet CHOULART was in the right. For notwithstanding all their analyses of the various con- ditions and offals of life, and of the lifeless blood drawn from the organism, together with their physical results, they are totally unable to represent, either in its healthy or diseased state, the process of life. All that has been brought against them, while discussing physiology, may 59 be repeated here while treating of the diseased conditions. Life, whether in health or disease, cannot be concocted out of chemical and physical processes. Professor VOGEL, of the University of Giessen, strikingly describes the pitiful and pigmy doings of many of these materialists as follows:- 66 By means of worth- less hypotheses they endeavour to advance victoriously there, where only the most indefatigable special inves- tigations, on the broadest basis, can compass the end. Supported by a couple of superficial chemical re-agents, they plaster up in several hours a chemical theory of a disease, without dreaming that the most zealous indi- vidual, carrying on the most careful and untiring investigations during a long series of weary years, would scarcely be able to lay even the foundation of such a beginning." And, most truly, pathology is, to this hour, without this foundation. Only when men shall begin, attentively and critically to observe the patient's life-looking at it organi- cally, undivided and unseparated, into nerves, blood, and tissues; with the conditions and offals, and the chemico- physical processes which accompany organic life; and shall read its laws from the living picture, thus composed-then, and not before then, may we talk of the commencement of pathology — of a real pathology; gathering its laws from itself, and not from extraneous sources not even from physiology; although this last, as a mighty auxiliary in explaining things, may, aye, and must, stand side by side with it! Then, shall the reign of supposition cease: then shall hypothesis, with its hobgoblins and phantoms, vanish before this true portrait of nature. Instead of the imaginary laws capriciously thrust upon nature, the real ones, discovered in 60 it by careful observation, shall effulgently shine forth, and be invariably the same for all practitioners, who esteem its laws more highly than their own opinions. With the discovery of these laws, the hitherto discon- nected members of pathology, will become an organic unity, and will thus form the healthy germ of a real science, which is true to nature. LETTER V. MATERIA MEDICA. As the mechanic must know his tools, so must the physician know the remedies which he requires for healing. What is the state of this knowledge? Let us look into the history and present condition of Materia Medica. Instinct and chance supplied the first materials, and mostly through laymen who very often could not vouch for the genuineness of the medicines, and frequently did not even know their names, much less could they indicate the diseased conditions against which they had been used. Such barren reports were collected super- ficially and without order, interwoven with supposition, and the one copied them from the other up to the present time. Criticism was never thought of. Instead of that, popular belief, went so far as to ascribe wonders to them, and from the outward resemblance of some to the symptoms of the disease, to suppose that those remedies had the power of healing exactly in pro- portion as their external appearance bore a resemblance to the inward state of the diseased conditions. This is the notorious theory of the signature. According to it, Ranunculus ficaria and Scrophularia endosa were said to 62 be curative in hemorrhoidal tumours, merely because both have similar knotty formations at their roots. The chief principal criterions in this theory, were colour, taste, and smell. There was a division into classes of the bitter, sour, astringent, and aromatic remedies. Thus, medicines of the most opposite effects on the human organism, were compounded and used one after another; for instance, colocynth and angustura, cascarilla and aloes, fel-tauri and cuprum sulphuricum. Another time the botanical system had to furnish the classification of remedial effects. Plants belonging to the same class were supposed to possess the same properties, and to be able to replace each other. In accordance with this new theory, the yellow carrot and the poisonous hemlock root should have the same properties, as both belong to the class of umbel- liferous plants; the same might be said of the cucumber and colocynth, of the potato and the deadly nightshade. Chemistry also had its turn. According to it, medi- cines were first separated into acid and alkaline; after- wards they were regulated in proportion to their atomical weight, so that e.g. bodies composed of equal parts of nitrogen, hydrogen, oxygen, and carbon, were supposed to exercise the same proportionate effects. on the human body. But just as little as the isomerous bodies of albumen and starch are of the same importance for nourishment, just as little are the isomerous medicines of the same healing power. I remind you of the alkaloids, caffeia and theia, quinine, and quiniodine. No chemical difference can be shown between ordinary and small-pox matter; none also between healthy saliva and that of rabid animals. Every- 63 where we meet with the same chemical combinations, as, according to Davy, in the red cabbage and water hemlock, and yet how different are their effects on the organism. To such absurdities, however, must men necessarily come, as long as the rules and standard for organic life, instead of being taken from itself, are sought for in chemistry and in physiology, which are foreign to it. However, many of the most experienced physicians felt long ago that this was not the way in which the effects of medicines could be ascertained, and that the question must be addressed to the organism itself. They conse- quently proceeded to experiments. These were first made on animals. However, such large doses were given, that only some violent symptoms were produced, under which the animal generally died, as the tortures. recorded in the annals of physiology sufficiently attest. There is not the slightest trace of an exact universal recognition of the working sphere of any single remedy, and it is impossible to obtain this even from more carefully regulated experiments, because the animal is unable to give any account of its subjective symptoms, feeling and sensation; so that the finer and more characteristic symptoms by which the inner- most character of the remedy is most clearly shown, can never be known. Moreover, the effects of many agents. on the animal organism are very different to what they are on man, owing to the peculiar condition of organisation and the different condition of excita- bility which manifests itself especially in the nervous. system and in the brain. Thus, for instance, the brain of mammalia has considerably less reactive power than that of man. The construction of the stomach, the intestines, and the lymphatics, alters in animals not 64 frequently the effects of a medicine. Goats and pigs digest hemlock and henbane, which, in the stomach of man or dog, would cause death. Hedgehogs can eat with impunity Spanish flies, and other acrid insects. The horse and the elephant are but little affected by arsenic; at the utmost, they experience a slight diarrhoea from it. Phytophagous animals with round. stomachs, such as rabbits and horses, cannot vomit, and the effect of an emetic on them is entirely different to what it is with men. Monkeys and squirrels die from a proportionally lesser quantity of prussic acid than man. A small dose of nux vomica kills a dog, whereas, the same dose given to a horse or a rabbit is compara- tively without effect. Colocynth, jalap, and bryonia alba, work powerfully on men, but scarcely affect animals. Unless attention is paid to these facts, great injury may arise from the use of medicines which have been tried on animals. The utility of such experiments on animals for a knowledge of the working of medicines is, there- fore, scarcely of any importance whatever, and men cannot be too prudent in making use of the results which have been thus obtained. Next come the records of poisoning by heroic remedies of persons willingly or unwillingly experi- mented upon. Here, however, the symptoms show themselves so violently and so tumultuously, that both health and life are endangered by them; and it becomes impossible to the most careful observer to follow up and clearly recognise the gradually progressive development of the inward connection, and the real peculiar character of the medicine producing these results. These also have but little value for Materia Medica, and being too often overrated, have been the cause of much mischief. 65 The richest and most important source of experiments was and still is, for most practitioners, those on the patient. Even in the present day, a professor says in his work on Materia Medica, which has been just published, that that mode is the only true one, and yet it must strike every re- flecting mind, that in the mass of symptoms presented, it is utterly impossible to distinguish those produced by medicine from those engendered by disease, and that both are too often confounded together, so as to disturb and destroy the characteristics of the medicines and the disease. If it is affirmed that the perception of the difference between the two is possible, then it can only be so for those who are acquainted with the medicinal effects. This is, to look upon the thing sought for as already found, a mode of proceeding, which, to say the least of it, is not rational. Add to this, that observations derived from the diseased organism are in the highest degree uncertain, as its vital activity in all or in single parts, is more or less altered by ill health, and its suscep- tibility to external influence suffers the most manifold modifications. Therefore PEREIRA is right in saying, "When we give medicines to the sick, the symptoms of the natural disease intermix with those which the medi- cines have produced, and they can then rarely be distin- guished with clearness and precision." This is rendered completely impossible by the circum- stance that a medicine is seldom given alone; but is generally mixed with others, cqually if not more power- ful than the remedy whose effects are under examina- tion. You will find thousands of examples of this in medical literature-prescriptions composed not merely of 2 or 3, but even of 10, 20, and 60 remedies, from which one is chosen by the Physician ad libitum, and F 66 indicated as the only efficient one, while the others accompany it as a troop of idle followers. Thus, from a mixture of quinine, arnica, and acidum muriaticum, that proved successful in a case of paralysis, it was said, "quinine is very efficacious in paralysis;" but no allusion whatever is made to arnica or acidum muri- aticum, as if these two had not produced the slightest effect. In another instance, mercury, hyoscyamus, and a mixture of valerian, arnica, magnesia, sulphur, and syr. citri, were simultaneously prescribed, and the result was entirely attributed to the mercury. You will agree with me, that from such capriciousness and super- ficiality, the very reverse of real knowledge, error and folly are engendered; and that the longer such a course is persisted in, the greater will be the chaos and con- fusion. This is the reason why that much respected physician, WEDEKIND, openly declares: "the theory of remedies, and the causes of diseases, contains much that is fabulous, and we may with the present system of mixing general remedies together, grow gray: and if heaven so permits it, snow-headed: but we shall never acquire experience." In perfect unison with his, are the words of MARCUS HERZ: "We mix several remedies together, and rely on their combined effect; or rather, through downright ignorance of which is the appropriate remedy, we throw numerous ingredients together, and trust to chance to produce the desired effect. We shall never in this way obtain a real experience of the efficacy of any particular remedy." The results recently communicated by RADEMACHER, and obtained by experimenting on the sick, are equally unsatisfactory and uncertain. He candidly avows that 67 he cannot indicate exactly the cases in which particular remedies should be given, and therefore is unable to fix the limits of their agency. Nevertheless, he has done far more for the advancement of medical knowledge by the simplicity of his prescriptions, and his anticipations of the organic efficacy of medicines, than have his en- raged critics who dream of finding the support of all medicine in organic bombast, or in the chemical analysis of the offals of life. These chemical ransackers are never at rest; as they formerly attempted to establish the efficacy of medicines from the proportions of atomic weight, so do they now seek to discover them in the changes which they produce in urine, excrements, pers- pirations, and inhaled air. Here they naturally stick fast entirely in the realm of the chemical and physical pro- cesses which accompany life, nor can the experiments they have made on the blood after it has been drawn from its organic association, and on the remedies they in- vestigate be excluded. From our discussions on Physi- ology, however, you will remember, that from such analysis and experiments it was found impossible to draw conclusions of the organic process of life, or indeed of the changes which are wrought in it by medicines, and as this is just what we want to know, the object we aim at is entirely lost. Therefore, the giving of medicines in such a manner is worse than rash, because as chemistry is the very reverse of organic life, life would thus be set on the hazard of a die. It would either vanquish chemistry and the physician, or it would be disorganized by both of them, and the patient would die. I will now rapidly demon- strate the impracticability of pursuing such a course. Take for instance a physician of moderate practice! where can he find the time required for chemical analysis, particu- 68 larly as such must be made with the utmost care, and on account of the ever-varying processes of life, must be re- peatedly gone over, if he would remain true to his chemi- cal principles? And precisely exact indeed must these ana- lyses be, as a few atoms more or less of oxygen, hydrogen, carbon, nitrogen, or chlorine, may convert the most harm- less bodies into the most dangerous ones, and vice versa, as chemistry proves by many striking examples. With all this required exactitude, it would be scarcely possible for a physician to treat more than a single patient per diem, and that single patient would most probably die under his treatment. Besides I very much doubt if every patient would, or could, hand over to the attending practitioner, admirably furnished with his chemical ap- paratus, such excrements, urine, sweat, and inhaled air; a circumstance which would render such a practice im- possible, and would involuntarily excite laughter, if the subject were not so excessively grave and serious. Yes, Moliere would have amused us certainly with some amusing description or other if he had encountered such a medical man, For on such learned folks He wrote the wittiest jokes.' The main support of this chemico-physical Materia Medica, is the maxim, that the process of medicinal action is only dependent on the chemical action which arises from the elements of medicine and those of the body, accor- ding to chemical laws. For this, however, we must necessarily know, in the first instance, the chemical combination of the medicine, which, in most cases, is surely discovered through analysis; and in the second instance, that of the elementary combination of the organism at all places where it came in contact with the 69 medicine. But this second requirement cannot be com- plied with chemically, and thereby the maxim falls to the ground. Moreover, it must be apparent to the most casual observer, that a physiological action does not necessarily imply a corresponding chemical one, nor does a chemical action necessarily imply a corresponding physiological one. What we have repeatedly said before, is also true in this instance, that the chemical and physical processes are completely controlled by organic life, and that they only find their sphere on the ex- treme limits of life. If most remedies, therefore, actually enter almost regularly into chemical combinations with the component parts of the body on their entrance into the organism, and undergo in and whilst leaving it chemical changes: so is their curative action not bound to this, as these combinations happen whether a cure is effected or not. Nor do the physiological effects originate at, or emanate from the place where the chemical changes of the drugs occur, nor are the medicinal effects, and still less the curative and chemical ones, simultaneous. Thus opium chiefly affects the brain, whether intro- duced into the stomach or the rectum. The curative action may begin weeks after the medicine has been taken, decomposed, and been expelled. The medicine also forms, with the organic component parts of the surface to which it is applied, chemical com- binations which are often indissoluble, as bismuthum nitricum, the calomel with albumen, saliva matter, and casein; and yet, in spite of this indissolubility, accord- ing to which it ought to be chemically unserviceable, it causes salivation and mercurial disease. Nay, the most indissoluble, and therefore chemically the most ineffectual preparations—such as mercurius dulcis-produce first of 70 all symptoms of mercurial disease. Many animal and vegetable medicines, as opium, musk, and castorium, un- dergo such changes in the organism, that they cannot be found in the blood and the tissues, and they cure, notwith- standing this. Most metallic salts, tannin, and many acids, possess the chemical property of coagulating albu- minous formations in the intestinal canal, or in the blood; they have, consequently, the same chemical action, and yet how different are they in their organic effect! It is, there- fore, an error to suppose that through chemical knowledge of this kind any real knowledge of organic effects has been obtained. It would also be mistaking completely the total organic action of a remedy, when, from its partial effect upon the blood, we would fix and determine its applica- tion in certain cases, as has been done with phosphorus, for the change produced by this remedy is not restricted to the blood alone, but extended over the nerves and the tissues; and there it does not rest fixed and limited, but continually progresses. But even to attain to this chemical knowledge, the activity of the organism is necessary, as it is only through the continuous moving of the liquids, and through the admixture of the medicines with the blood, the tissues, and the secretions, that the chemical changes arise. Ex- These cannot be imitated on the lifeless blood. periments on the combination of a remedy with the firm component parts, or with the blood-experiments outside. the living organism—are consequently insufficient even for ascertaining the chemical changes which are produced by these remedies in the organism on the limits of life. The intermixture of drugs with the blood gives, therefore, only a doubtful answer to the question-how is the medi- 71 cine changed in the living circulating blood, and how is the blood changed by the medicine? So also does the application of a remedy to the dead coats of the stomach furnish no answer to the question-how is the medicine changed in the stomach of living man, and what are the changes which it and its contents undergo by the medicine? Would the advocates of chemistry but maturely weigh the constantly recurring fact, that in the cure no proportion exists in the quantity between disease and medicine, while the difference between a cure and a chemical process is immense. The smallest dose can cure the greatest disease. The factors of chemi- cal processes are, therefore, not those of the organism which do not determine its power or duration, but the process of cure is superior to the chemical and physical ones, is more organic, and therefore more independent, so that it is brought about by the chemical changes of the drug, in the organism, as well as by the chemical changes of the organism through the drug, and also without these chemi- cal changes. May they also consider, that through the chemical changes of the medicines in the organism bodies of the most various kinds, and often of the most contrary effects, are created; and that it is impossible to describe exactly either the time or the place of the transformation, or the products as they depend on the combinable matters which are found in the organism in very versatile forms; and that, therefore, the recognition of the chemical properties of the originated bodies is more likely to remain a wish, than to become a fact! Thus, the carbonates of potash and earths are soon changed into hydrochloric and lactic acids; sulphur into hydroguret of sulphur and sulphuric acid, which last regularly combines with other bases, potash or 72 soda; iodine in iodide of hydrogene; the salts and oxides of mercury, according to MIALHE, into chloric acid; chlorides and bichlorides. In the tissues they are again decomposed, and deposited as reguline quick-silver; but in the saliva they are secreted in the form of cyanic quick-silver; arsenic into arseniuretted hydrogen gas, which in its powerfully poisonous effects, soon destroys organic life, and into kakodylic acid and sulphate of kakoplatylicoxide, which in very large doses of seven grains does not affect rabbits poisonously. The materialists, in their analysis, could not even discover, as you will recollect, the different degrees of formation and dissolution, and still less the organic process of life itself. You will find them here in the same predicament as regards the determination of the effects of medicine. Here, also, they know the medicines but partially ; they cannot indicate the different chemical degrees of change with certainty, and the great object of Materia Medica the knowledge of the changes effected by the drug in the process of life is entirely hidden from them. Notwithstanding all this, too many physicians are dazzled by them, and look upon the human organism as a mere chemical retort, and in the same manner in which they saturate alkali with acid, so they also impregnate the organism with drugs, until it is totally disorganised, and the unfortunate victim is consigned to the grave and oblivion. Schultz aspired to an organic Materia Medica. He says, as many have done before him, that the real nature of the organic working of medicines cannot be explained by chemical and dynamical theories; but that men ought to study the germ of remedial action, its primitive action and effects, and conceive them in their 73 organic combination. Hereby the sensual, the chemical, and the physiological properties of remedies should be attentively observed, as they often, in experiments, fur- nish hints respecting organic action. What do we find after all these fine words? Experiments on animals and on the dead blood-on blood deprived of all its organic connections—and you are to take such one-sided views, embellished as they are with learned bombast for the organic effects of medicine! It is but natural that such false coin should be re- fused, which will never redeem life from the fetters of disease. To complete the confusion in Materia Medica, which, by the indicated ways, could never arrive at any thriving development, speculation, and the rage for systems, have powerfully contributed. I will not fatigue you with the enumeration of the many theories which often directly contradicted each other, and which, like true ephemeral thoughts, swarmed forth from the marshy ponds of scholastic knowledge the one day, to expire on the next. They were nearly always the transposi- tions of formerly existing ideas, suppositions to which experience had to submit, affirmations and conclusions all connected among each other, but only by chance with nature. Opinions of Phenomena, according to a given idea, the variety of which was overlooked or denied, in favour of a unity in our view of the matter which recommends itself as so-called scientific precision, but is as remote from true science as supposition is from truth. The remedies were also differently classified according to the different systems; they were placed from one par- tition into the other, and endowed with various proper- ties, which were often completely opposed to each other. 74 Sthenic and asthenic diseases were created, and for them also a scale of strengthening and weakening remedies. In accordance with another theory, in some diseases, oxygen, nitrogen, or carbon, predominate, and there- with arose in Materia Medica divisions of remedies containing nitrogen, oxygen, carbon, or hydrogen. In a third theory, diseases are based on a disproportion between the so-called factors of sensibility, irritability, or reproduction, and therewith a host of remedies are again pointed out, which change, increase or diminish these factors. Others see in certain diseases an excess of phlogiston, and immediately collect a number of anti- phlogistic remedies. The so-called dissolvants, stimu- lants, blood-purifiers, anti-acids, sudorifics, palliatives, anti-spasmodics, &c., owe their names and classifications to general ideas, which have been conjured up by a kind of prosaic poetry of healthy and unhealthy vitality. On this subject listen to the eloquent Dr. NEHRER. "The classification of remedies according to vague pathological ideas, physico-chemical peculiarities, or striking primi- tive effects on healthy and diseased organism, shows clearly that a practical physician, on seeking for a remedy against this or that disease, finds seldom a single but generally several similar, and in most cases a whole host of remedies, or several different methods recommended to him. For instance, if he seeks, during the classification of medicines which affect sensi- bility, irritation, and reproduction, for a remedy against typhus fever, he has at once the whole materia me- dica at his disposal. In the classification of remedies which affect vitality by diminishing, altering, or increasing it, he will find that all remedies can be ap- plied in Asiatic cholera; for there the activity of the 75 outer skin must be increased, that of the inner onc diminished, and the whole must be altered to save the patient. If we divide them into two great classes, for plastic and animal life, with sub-divisions of soothing and stimulating medicines; and if it be true that each deeper suffering of the one sphere of life affects the other, then may we indeed at pleasure make use of the whole treasury of medicine when any very serious case is involved, without, in the slightest degree, overstepping the rules of dynamical Pharmacology." He adds, "these methods do as yet not guide to one remedy for a certain case, but always several together are grasped at, because the separate ones are too little known." Thus the compound mixtures which are still in use, originated and are sent into the body with the pious wish, that each remedy may operate in the intended manner! Mark the words of some one else, which were called forth by MONTAGNE's remarks on the dangerous com- pound mixtures, which he feared might lose or change their billets, and breed disturbance in the quarter assigned to them. "In our prescriptions, we string remedies together in the same way we do pearls, and compose a single remedy from out a dozen ingredients in the same manner as a corporalcy is formed of as many men; not to speak of the simultaneous administration of a second or even of a third remedy of a like compound nature, none of which may interfere with the other. The physician, an agent as it may be of life or death, stands advising and helping with all the different parts of the body in direct com- munication, packs his remedies for them all in artistic mixtures, and sends them into the stomach, which, like a well regulated post office, assorts the medical post-bag 76 and forwards the contents promptly to their proper address and destination-so many drops or grains for the abdomen-so many for the nerves, etc. Every part receives what was destined for it, and no more, and in each the intended effect takes place undisturbed by all which in the meanwhile may be going on in the same manner in the rest of the body." I have already said to you, that by this transposition of medicines into other compartments, according to the reigning system, the most varying and opposite properties were put forward. Hear a few examples. Drs. THOMP SON and MURRAY look upon opium as a stimulant, while CULLEN and BARBIER consider it as a sedative; MAYER thinks it both, viz., a stimulant for the nerves and the circulating system, and a sedative for the nerves and digestive organs. ORFILA will not allow either. MÜLLER calls it a medicine improving the state of the fluids. The great SYDENHAM would not have been a physician without it, as he believed medical science to be imperfect without it. The equally great STAHL condemns it as absolutely detri- mental, and declares every administration of this medi- cine to the patient a downright crime. Another remedy -mercury, is classified by CHAPMAN, CULLEN, YOUNG, and EBERLE, among the salivating remedies; by THOMPSON, EDWARDS, VAVASSEUR, TROUSSEAU, and PIDOUx, among the stimulants; while CONRADI, BERTELN, and HORN, regard it as a sedative. Dr. WILSON PHILLIPS thinks it a stimulant in small, and a sedative in large doses. MURRAY ranks it among the nervine medicines: VOIGHT among the dissolvants; DUNDELIN among the liquifying; BEGIN among the revulsive; GIACOMINI among the anti- stimulants, or hyposthenic. BARBIER describes it with incertæ sedis. Therefore, Rust could rightly say: the his- tory of opium is the history of medicine, as in the various properties which have been forced upon it, the different systems and theories of medicine are reflected. Nor is it any exaggeration to assert, that there is not a single indication for the administration of opium, which has not been contradicted. Is What a painful delusion for suffering humanity! it not apparent that every remedy, like every thing else, has its own peculiar properties remaining always the same, unaffected by our views and theories, and that it, on account of these very properties, incites the organism also to peculiar reactions, which in their genetic develop- ment, reveal to us the real working organism of medicine? But instead of putting questions to nature through calm unprejudiced experiments, and of reading its laws in the untroubled answers, the professors of Materia Medica preferred to become pharmacological poets, enforc- ing their phantasies as laws upon nature, and astonish- ing us with their fables of remedial effects. They laud a remedy to the skies to-day, and to-morrow it is dethroned by another. Iodine, creosote, prussic acid, mercury, and quinine, have in their turn had their day of glory and of downfall, and many others will, without doubt, yet have the same fate. It is here that the practitioner's ignorance of the real effects of medicine springs to light. As the various views that were taken of the next cause of delirium tremens proved to you the unsettled state of physicians in Pathology, so do you find again exactly the same inexperience and uncertainty among them in Pharmacology, as is strikingly shown in the examples of opium and mercury. This hopeless condition has been repeatedly and sharply alluded to by the most celebrated men. I will quote a few to you. GIRTANNER says: "Our 78 Materia Medica is little else than a careful compilation of fallacious observations made by the medical men of all ages. There are certainly a few valuable results among them, based on experience; but who would waste his time in picking out these thinly scattered grains of gold from the immense masses of rubbish which medical men have been heaping up for the last 2000 years?" Dr. CULLEN says: "The different Materia Medicas are full of wrong conclusions, although they are said to be obtained by experience." FREDERIC HOFFMAN asserts: "That medical men are deceived in the majority of remedies, because their real properties are still hidden in darkness, and a general code of nature's laws for their wholesome application in disease is utterly wanting." Professor JÖRG expresses his amazement at having found such contradictory results in the opinions of Pharma- cologists, and declares positively that as far as his ex- periments go, he has scarcely ever met with a remedy whose real properties were known. KIESER says: "In many instances the old proverb is true, that 'the remedy is worse than the disease,' and the physicians more dangerous than the malady." The celebrated REIL says: "Our comprehension of medicinal effects is merely em- pirical. All our talk about changing, purifying, liquids, improving and dissolving remedies, is for the most part nothing else than a senseless traduction of inanimate nature in the living one." Therefore, it is even in the present day a vain and fruitless attempt to seek for a principle by which the effects of medicine may be explained. After this, Pro- fessor PFEIFER's words will appcar justifiable, when he bluntly says, "that on the definition of medicinal 79 effects according to any a-priori method, arising from chemical or physiological points of view, little or no stress can be laid, because physiological chemistry is still in the earliest stage of infancy." A little further he adds: "Medical men who just enter into practice and who wish to distinguish themselves by a judicious treatment of the sick rather than by a glittering no- menclature, cannot do better than to forget as quickly as possible all they know of medical effects from lectures. and manuals. At the beginning of this letter we asked, whether physicians know medicines, the tools. with which they are to work, as the mechanic knows his; and in concluding, we regret to be forced to answer the question by-No! they do not. It will never be light in the Egyptian darkness in which they grope, until, with unbiassed and unpreju- diced minds, they decide on treading the experimental empirical path. Supposition and hypothesis must be banished for ever; chemistry, physics, and physiology must no longer serve as standards, but must only be utilised for explaining. Materia Medica must and can only be developed by and through itself. No solitary systems of the body, as the blood, the nerves, or the tissues, must any longer be considered as the sole vehicles of remedial effects. It is only by a thorough comprehension of the changes occurring through medicines in the entire organism, as well as in the blood, the nerves, and tissues, in forma- tion and dissolution, and the other functions of life; carefully following them up from the commencement to the end, and observing the chemical and physical pro- cesses which are taking place on the boundaries of life. as well as the residues (offals), that medical men can arrive at a real knowledge of the true action of medi- 80 cine and the unclouded laws of organic changes, and then they may truthfully affirm that they know their tools. May what has hitherto been but a wish for most medical men soon become a reality, for their own tranquillity and honour, and for the welfare of suffering humanity. LETTER VI. THERAPEUTICS.-THE ANTIPATHIC OR REVULSIVE METHOD. THE communications I have made respecting Physi- ology, Pathology, and Materia Medica, will, no doubt, have convinced you that these separate branches are very imperfect, and that parts of them are actually rotten. It is therefore apparent, that Therapeutics which are derived from them cannot be sound and true to nature, as their structure reposes on too weak a foundation. But I will not anticipate. You may draw your own conclusions from the actual exposition of the concatenation of these different branches to Thera- peutics. The method which has been and is still most in use to cause this concatenation is the so-called Antipathic mode of treatment, based upon the antagonistic principle, contraria contrariis. According to it the very opposite state to that of the disease is called forth. In the same manner as you expel heat by cold, cold through heat, moisten a parched tongue by a cool G 82 draught, or satiate hunger with food, so Antipathic prac- tice does with diseases. Against constipation a purgative is prescribed; against diarrhoea an astringent; when the circulation of the blood is too slow something is given to accelerate it; if there be too much heat in the blood, the so-called cooling medicines, such as saltpetre, tartaric acid, and lemonade are given; in a case of atony, tonics are administered. By means of chemical laws, the altered proportions of mixtures are sought to be improved; acids are neutralised by bases, and bases through acids; want of oxygen is replaced by acids; superfluous albumen is forced to coagulate through nitrate of silver; in short, the human body is changed into a chemical retort. Assuredly this method is very enticing, is it not? It seems so simple-so very natural! but, I must add, -it is so only to superficial minds. For there exists no antagonistic principle between healthy and diseased conditions, the condition opposed to that under which the patient labours cannot therefore, be called forth. For both healthy and diseased conditions are but the expression of aggregate life, only, under altered inward or outward conditions, or of both together; it is, there- fore, necessary, above all other things, to understand the inward process of life, to render it possible to pro- duce its very opposite state. But it has been sufficiently proved to you, that the actual process of life in its healthy and diseased states is a perfect riddle to us-that we know as little of the inward cause of disease, as of that of healthy life; and that it is, therefore, absolutely im- possible to call forth with certain knowledge a state opposite to that of the disease. Remember, also, how it stands with the knowledge of the drugs, with which 83 the doctor tries to create the state contrary to that of the disease. Can you imagine anywhere else, a more Baby- lonic confusion than that which exists in Materia Medica. How is it possible to produce certain intended effects in the organism with drugs, with the action of which on the human body we are as yet ignorant? How uncertain and dangerous such attempts are, must be apparent to everyone! This endeavouring to ascertain the essence of the diseased conditions, and the mode of cure established in accordance with the supposed recognition thereof, with drugs, the effects of which were equally arbitrarily invented as the essence of the diseased condition itself, has, in times present and past, been the cause that medical men have committed the greatest errors and blunders; has engendered so many erroneous thec- ries and fallacious systems, has occasioned such numerous disputes and mistakes among medical men, some of which have been of so serious a nature, that physicians. should be very careful in regulating a mode of cure from a mere theoretical view of disease. But, even this theoretical idea of the existence of disease, cannot, in many cases, be obtained, even by allowing the fullest play to phantasy, much less can we remove with the invented properties of drugs, the invented, though not really found cause of disease. We cannot follow up, therefore, what is called the indication, to annul the original cause of disease. And how do they get out of this dilemma? Several indications are jumbled together after the different and particularly important appear- ing disturbances of activity in the separate systems and organs; each striking symptom has an antagonistic remedy opposed to it, and, all of them combined, are sent in to 84 the organism with express command, that each shall work in its indicated place with all the properties which are supposed to belong to it; without considering that every combination of remedies, the properties of which have been ascertained, in a rational empirical manner, and not merely invented by mere hypothesis, produces effects which may not and cannot be judged from the separate component parts. Hereby, the treatment of disease is lowered to a mere symptomatic one, leads to mere snatching at symptoms, because every association to explain these symptoms is wanting, and tends to the old jog-trot way, as is shown by so many narratives of cures. Because they stick to mere externals, no thorough cure can be effected. Not seldom do we find that, to satisfy entirely contradictory indications, entirely opposite reme- dies are united together. Does the curative effect not. happen, as it is but natural, the cause is not sought for in the quality but in the quantity of the remedies. Therefore, the doses are increased, until they have become out of all proportion. Hereby the standard to value the action of every separate drug is lost. The medi- cinal symptoms cannot be separated from those engen- dered by disease. Aggravations and symptoms arising only from the drugs, are looked upon as emanating from the disease; and the medicinal doses, instead of being diminished, or entirely left off, are continually increased. The patient becomes thus literally inundated with foreign substances, and their baneful effects are not long in following. The great arsenal of drug-diseases develops itself either on its own account, or combined with the disease against which the remedies have been prescribed, and are of a more dangerous and troublesome nature 85 I than the disease whose place they have taken. I will only draw your attention to the disease produced by quinine and mercury. How often do we find, from abuse of quinine swollen abdomen, induration of the spleen, liver, and mesenteric glands, dropsy, defying every treatment, and which accompany the pale ema- ciated patient unto the grave. The evil effects of mercury are even more formidable and destructive. will enumerate a few of them to you: Chronic disease of the liver, swelling of the glands, chronic headache, mercurial rheumatism, swelling and caries of the bones, general debility and emaciation of the body, cutaneous eruptions, chronic affection of the lungs, of the stomach, of the abdomen, inflammation and ulceration of the interior of the mouth, loosening of the gums and of the teeth which fall out, suppuration and mortification of the jaw bones, complete enervation, and, finally, death from apoplexy. Besides these, PEREIRA observed the following effects happening after injudicous doses of mercury:-Excessive salivation, urination and perspira- tion, inflammation of the eyes, trembling of the muscles, sometimes accompanied by stammering, and termi- nating in paralysis, epilepsy, or apoplexy, asthma, amaurosis, and hypochondriasis. RUST says, that, if syphilis combines itself with mercurial disease, its most dangerous and incurable form originates. If you remember what I said to you whilst discussing Materia Medica, that mercury had been found deposited in a pure metallic form in the cells of the bones, you can easily comprehend the danger and incu- rability, as the cause the poison itself is not removed out of the body, and, therefore, continually remains the 86 source of the most varying and most painful disturbances of life. Often the indications will not allow themselves to be united at all, and physicians get in a most dreadful di- lemma. For example, somebody suffers from inflamma- tion; it is believed that bleeding will save him, but the debilitated state of the patient forbids it. In spite of all collegial consultation, they cannot agree as to whether they must let the patient die from inflammation, without bleeding him, or let him die from excessive debility after having bled him. Another suffers from weakness of the digestive organs, with turgescence of the blood, and con- gestive fits. In consequence of the latter they would like to give him cooling compound salts, and yet they are afraid of weakening the stomach still more by so doing; they would like to strengthen the latter through tonics*, and yet they are frightened at their heating effects on the blood. On another occasion, sleeplessness has to be com- bated. Morphium is given first in small, and, when these no longer help, in constant increasing doses, until a complete opium frenzy appears. Now the strongest coffee is given in large quantities: through it the patient, already inclined to congestive attacks, gets into a very excited state, and, to allay the storm in the vascular system, blood-letting is in all haste resorted to, which causes excessive weakness, and engenders still more sleeplessness. So it goes round in a circle until death puts an end to this sad catastrophe, and frees the patient from physician and disease at the same time. * Mr. Watt, late Editor of the Chemist, informs me that he has recently discovered that all bitters injure digestion, because they turn the gelatine into leather.-Note of Translator. 87 This symptomatic treatment, which is a natural con- sequence of the constant hunting of medical men after the next cause of disease, becomes the more dangerous, as hereby the frequent useful reactions by means of which the organism endeavoured to equalise its disturbances, are suppressed; so that disease can throw itself, with re- newed vigour upon the nobler parts of the body, causing death, or a disease which only terminates in death. Not seldom do we find the symptoms alleviated for a short time, but the disease itself continues to increase inwardly, by stealth until it breaks out afresh, more severe and obstinate than ever. Thus, a child suffers from continued diarrhoea. The physician gives opium, the diarrhoea ceases; but a severe inflammation and extrava- sation of water on the brain occur, and a few days afterwards the parents have only a corpse. A patient suffering from chronic liver disease is attacked with vomiting; this is soon stopped, but now the liver disease. develops itself with increased violence, such as degener- ation, enlargement, the formation of abscesses, and finally causes death through dropsy. A child is freed in two days from a moist eruption on the neck by means of eau de coulard (lead-water.) On the third day it is attacked with severe inflammation of the lungs, which, in spite of the best treatment, does not get better until the eruption has again reappeared. Another has a herpetic eruption on the upper part of both arms; he is cured within eight days by applying a certain ointment to it. How happy he is to be relieved of so tiresome a complaint, but his satisfac- tion is only of short duration: he gets shortness of breath; a cough, slight at first, soon becomes very severe, accompanied by copious expectoration of matter, 88 and the patient dies from consumption, in spite of all physicians, in spite of his visiting watering-places and going to warmer climates. Facts like the above can be met with each day in the practice of every physician, and will continually occur as long as they do not take as object of cure the entire organic picture of disease, but rather the so-called next cause of it, and endeavour to produce its very opposite state, although, as I have mentioned already, there does not exist any opposite state between healthy and diseased conditions. Ask them the contrariety of many pains, affections of the mind, dyscrasies, etc., and believe me, they will not be able to answer you. At the utmost they may venture on some hypotheses, but these cannot bear inquiry. Physicians, in following such a course, vary in their opinion of the next cause of a certain disease, according to the education they have received, and, therefore, as a matter of course, concerning the opposite states which they endeavour to create. He who belongs to the dynamical school will act diffe- rently from the follower of the chemical school. The patient's life, therefore, depends on the opinion, degree of education, or the caprice of the medical attendant. The treatment of the gout forms a striking example: -Here the most renowned physicians stand in as direct opposition to each other as night to day. Every one acts as he thinks proper: what the one recommends the other rejects. CHALMERS recommends emetics as a pre- ventive against a threatening attack; MUSGRAVE, on the contrary, powerful purgatives, which are completely rejected by BOERHAAVE and WARNER; STOLL and GRANT recommend wine, spiced food, bitters, and preparations of iron; FOTHERGILL, Dover's or James's powder and 89 antimonial wine with opium; WILLIAMS, however, exacts that musk and castoreum should be taken in very large quantities, the former in doses of 20 to 30 grains every six hours, the latter in doses of 30 grains; WOLF advises the gratiola; GILBERT and VANDER HEYDE insist on copious bleeding, which STOLL and MEAD opposed, because they only experienced evil effects by so doing, in which they are confirmed by SYDENHAM; Barthen and VOGEL recommend very cold drinks; CADET DE VEAUX, very warm water, in consequence of which I witnessed how a patient suffering from gout fell down and became an incurable maniac; GIANNI advises cold applications to the suffering parts; BUCHAN, however, recommends warm sheep's wool to be applied. You see a real quodlibet of the most heterogenial remedies! Does this throw any light on the treatment of the gout? But they do not even agree respecting the diet of per- sons so afflicted. BROWN exacts that no vegetables or watery beverages should be taken, and prescribes free use of wine and meat; DERWIE recommends water as a daily drink, and forbids wine; LINNÉ advises a plentiful par- taking of strawberries; CULLEN assures us that during the sixty years of his practice he never cured a single case of podagra, and considers medicines of no avail in this disease, he recommends a good deal of bodily exercise, and to abstain from meat. Although BOERHAAve, Fred. HOFFMANN and VAN SWIETEN wrote a great deal upon gout, yet they were unable to cure themselves from it, and it is a well-known fact, that the great SYDENHAM, who published a work upon gout, died himself of podagra. This unsettled state among medical men in the treatment of the gout, caused Dr. Girtanner to say: -"So much is clear from what has been said, that 90 podagra is a disease, of the nature and cure of which we are entirely ignorant, and of which the doctor knows as little as the patient who sends for him. Since the time of Hippocrates, we have not advanced a single step as far as regards the treatment of this disease. This is the fruit of medical experience extending over upwards of 2,000 years." If this is the case with podagra, a disease which hap- pens so frequently; which attacks the richest and most dis- tinguished persons in the kingdom, who promise golden. fruits to the physician who can free them of their suffer- ings; a disease which has been examined and enquired into with particular care and considerable interest by medical men of all times, because they nearly all suffered from it themselves: what, then, can be their knowledge of other diseases, which happen more seldom, or attack only the poor, in whom medical men take a consider- able less interest. The inability of indicating the next cause of disease on one side, and the conviction of being ignorant of the medi- cines which cause the opposite state of the diseased con- dition, has given birth to the so-called revulsive method, to complete as it were the antipathic mode of treatment Very likely it arose from the repeated observations, that certain diseased conditions vanish on the simultaneous appearance of others. A system was formed of the sympathy and antagonism of the different organs aud structures of the organism among each other. Every component part of the organism had a certain relative value allotted to it. People were presumptuous enough to weigh, as it were, the importance of the one against the other, and thus according to these fixed laws of sym- pathy and antagonism revulse discases from nobler 91 organs to lesser ones. Such changes of diseased condi- tions are doubtless facts, but as certain is it that as often transfers occur from the lesser organs to the nobler ones, that ordinary and more dangerous forms of disease alternate with each other. An inflammatory irritation of the membranes of the brain can resolve itself by a defluxion from the nose, looseness of the bowels, or a rheumatic exanthem, but it may also begin to develop itself after the suppression of these conditions. Head- ache, giddiness, apoplectic fits, are cured by a flow of the hæmorrhoidal vein, but are as often caused by a sup- pression of the latter. These discharges can, therefore, serve a bad as well as a good purpose. It is indeed apparent that the original notion of the revulsive method, is a very deceitful and consequently a dangerous one. It is the more deceitful and dangerous, as you will remember what has been said whilst discussing physi- ology, that the separate systems and organs are too little understood to enable any one to fix the laws of their sympathies and antagonistic principles. The first and absolute requirement for the establishment of this system has therefore as yet not been found. Moreover, a complete knowledge of the remedies used in this system is wanting; a circumstance of no small importance, and productive of the most dreadful consequences. Antipathic practice tries to transfer disease by means of friction, cupping glasses, sinapisms, artificial external ulcerations, vesicatories, irritating ointments, foot-baths, and injections. Besides these mostly peripheric revulsions, it endeavours to overcome disorders by increasing the action of internal organs even unto a state of disease. Thus, besides the skin, the intestinal canal and the kid- 92 neys have especially been laid hold of, and consequently purgatives, diuretics, and sudorifics have been prescribed. Quite an arsenal of these medicines is in readiness, to produce for a moment's relief,-a lifetime of suffering. All that has been said about symptomatic treatment may be applied to this. Physician and patient are deceived in the correct appreciation, of the nature and course of disease, and thereby the doors are, as it were, opened to allow a free entrance to the most dangerous mishaps. Through the continual use of purgatives, which must be increased to maintain their effect, the intestinal canal is often ruined for life, and but a momentary relief is afforded, and an increased inclination towards constipation produced. The direct and indirect conse- quences are-enlargement, induration, and inaction of the liver, want of appetite, bad taste in the mouth, weakened digestive power, pains in the chest, colics, piles, various diseased conditions of the rectum, head- aches, and nausea, etc., etc. The other parts of the body are also often ill-used by this method of cure; setons and issues are continued for years; caustics and cauteries are used in so wanton a manner, that hos- pitals are transformed into real chambers of torture. Frictions with tartarised antimony cause, in no few cases, deep and extensive ulceration, which leave ugly scars behind. Fontanelles (issues) weaken the part to which they are applied, often cause real atrophy of the same, and produce an offensive smell besides. Plasters of Spanish fly repeatedly cause affections of the bladder; and the application of caustic belongs to the most dreaded of operations on account of the pain it produces. Truly it is a desideratum to be freed from such tor- 93 tures, through which the one part of the body is made ill to cure the other, forcing one, as it were, to put up with several complaints. We often find that such remedies leave as painful and obstinate diseases behind them, as those which they ought to have removed! PEREIRA says, alluding to the effects of the Spanish fly, "Suppuration and mortifica- tion are not uncommon; the latter appears occasionally after eruptions, in particular after measles. I have myself witnessed the occurrence of death, in two in- stances." I add, that anthrax or carbuncle, whereby life is always endangered, does not seldom happen in conse- quence of the repeated application of the Spanish fly. VIRCHOW advises to be very careful in applying can- tharides whilst treating inflammatory diseases, as it is so apt to produce secondary effects, such as catarrhal and croupy affection of the urinary organs. You see from this how badly it stands with the revul- sive method. But ought not medical men to have been led by these very secondary symptoms to consider that these means which were applied had other effects besides those produced on the outward skin-that the particles which have been absorbed and taken up in the fluids produce quite different effects on the inward organ- ism—and that the cures which may have occurred were only caused by this internal absorption, and not through the torturing outward action of the medicine? It is true, that to obtain a clear insight into these matters, a complete knowledge of the effects of medi- cines is absolutely required; but this most medical men. do not possess, and this will last so long as the present medical education continues. Thus, if they wish to irritate the skin, they apply a number of medicines, 94 without any further consideration, replacing ad libitum the one by the other, such as horse-radish, mustard- plaster, mustard oil, plaster of cantharides, ointment of tartarised antimony, croton oil, each in succession in one and the same case. They do not take into considera- tion that these remedies, though applied outwardly, are partly absorbed, and produce in the organism each their peculiar effect, and will thereby prove either hurtful or curative. I will relate a case, which deserves to be mentioned here: A lady suffered from chronic inflammation of the uterus, accompanied by the most severe pains in the abdomen, in the sacrum, coccyx, and in the loins. Most insupportable to her was the feeling as if a heavy weight was attached to the coccyx. All functions were more or less disturbed. Sleep was almost banished, and deep melancholy had set in. The cleverest English practitioners treated her during more than nine months, without the least success, making use of all inward and outward remedies. Blisters of cantharides had been ap- plied for a long time over the sacral region, causing most dreadful agony to the patient. At last one of the physi- cians applied tartar emetic ointment, during six weeks at the same place, causing thereby a continued mattery discharge, and see, a gradual recovery took place! That was a first-rate result of the revulsive method, you will say; but wait and listen to the end of the story. Some years afterwards, when deep sorrow had affected her, the old complaint returned afresh in the same form, increasing every week in violence. I was called in to attend upon her, and having care- fully inquired after every circumstance, I gave her, thrice a-day, grain of tartar emetic, and in three 100 95 days she was cured. I was led to do so by the thought, that, in the first instance, the absorption, consequently the inward action and not the ulceration produced by the antimony, had occasioned the cure; and having, by a careful study of the remedy, found that I was correct in my conclusion, I acted accordingly, and the happy result proved I was right. If this view of the revulsive method was more gene- rally adopted, and practitioners would only endeavour to obtain an organic pathology and Materia Medica, how much suffering would be spared to the patient, and how much sooner would he, in many cases, be restored to health. You have seen the vain result of both the antipathic and the revulsive methods, when they are applied sepa- rately. But increasing distress often causes medical men to apply both at the same time, and by so doing it. is clear that the uncertainty in forming an opinion of the disease, as well as the result of the separate methods, and the dangers to the patient, become the greater. The following may serve as an example. Against a nervous fever with torpid form, all sorts of ex- citants, such as arnica, serpentaria, angelica, sulphuric ether, etherial oils, wine and spirits, ammonia, musk, phosphorus, opium, castoreum, camphor; in addi- tion to this, quinine, tonics such as quassia, gentian, finally iron, are given : warm and cold baths, vesicatories, sinapisms, irritating injections; in alternation with eme- tics, etc., are prescribed. Such a treatment AUG. Gottl. RICHTER advocates! HUFELAND nearly the same. Com- pare with these SCHÖNLEIN's views of the same disease, and his mode of treatment. He says: "The views of medical men as regards the treatment of disease are in 96 Whereas some, none more at variance than in this." with MARKUS at their head, take away the blood by pounds at a time, and consider that the strongest bleeding is indicated, others only expect good from stimulants, and give, in the very beginning, musk, cam- phor, serpentaria, ammonium, etc. If we go through the entire Materia Medica, we do not find a remedy which has not been given in typhus. "The more reme- dies for a disease, the more uncertain its treatment; and experience has confirmed this maxim, for mortality in typhus has increased in proportion with the remedies." Thus the same disease, and that one of the most fatal, is treated by two physicians with entirely different and opposite remedies. No wonder the mortality is 50 per cent.! which, as SCHÖNLEIN himself says, cannot be less attributed to the doctors than to the disease. "As regards the treatment itself," says SCHÖNLEIN, "it may and can only be a mere symptomatical one." SCHÖN LEIN honourably acknowledges, that he does not know this disease, and that he only skirmishes with the separate symptoms. He applies leeches against the congestions, and emetics against the affections of the stomach. Opium and nux vomica, so strongly recommended by RICHTER, he considers perfectly useless, and instead of them gives his patients sal ammoniac and antimonial wine. Against the alteration of the blood he prescribes alum, together with nux vomica, and finally presents the skin with blisters and baths. Does this magnificent pattern-card not strike your fancy? Is it not the most pitiful testimony of the dis- organised state of medicine,—a blow which one of the first leaders of so-called scientific medicine strikes 97 in the very face of organic science? with green wood, what must we not to that which is dry? And if this occurs expect to happen Shall I also tell you of the cholera, whereon a legion of books has been written, and respecting the nature and treatment of which they know about as much in the end as they did at the beginning. Now it is supposed to have its seat in the spinal marrow, and now in the blood, the bile, or in the intestines. One considers. it intermittent fever, the other typhus, epilepsy, asphyxia, colic, dysentery, diarrhoea, catarrh, intes- tinal exanthem, animalcule, poison, or atmospheric coal. The one took away pounds of blood from the unfortunate patient, and finished both patient and disease by so doing; the other gave mercury in scruples, where grains would have sufficed to poison healthy persons; a third gave magisterium bismuthi, according to a theory invented by himself—a wretched coinage of the brain! Others recommended some- thing else. In fact, it needed only an individual to recommend a remedy, and instantaneously a host of admiring followers experimented with it upon the unfortunate patient. Can it still astonish you, that under so mad a treatment, mortality rose from 52 to 67 per cent. I must not omit to mention the specific mode of treatment, based upon repeated observation, that certain remedies have proved beneficial in certain diseases. So quinine was given in intermittent fever, sulphur against the itch, and mercury against venereal disease. But you will remember, from what has been said of this method, when speaking of Materia Medica and Pathology, that the choice of the medicines for the H Uor M 98 diseased conditions, is just as uncertain and often even as impossible as are the clear and individual signs of the diseased conditions for certain medicines. This method, in its actual state of development, is, therefore, utterly untrustworthy, although it contains a good deal of useful material, and many healthy germs, which need only the fostering hand of real science to flourish. Mou LETTER VII. THE PHYSIOLOGICAL METHOD.—THE MATERIALISTS. THE so-called physiological expectative method has recently assumed an important appearance; let us con- sider it attentively. With it, Physiology is to be the thread which guides through the labyrinth, maintaining order, and encircling the whole with a scientific band. But Physiology is, as has been already shown to you, a page full of censural gaps, points of interrogation, and dashes. We know not even the exact structure of all the organs, still less their functions. still less their functions. In what darkness sanguification, nourishment, and, above all, nervous life, are enveloped, is known to you. How is light to come there? Even supposing it were light and clear, it would, at the utmost, as has been said before, serve only as an explanatory science to Pathology; as normal figures which might in some degree assist in forming an idea of the abnormal course of the diseased conditions; but cannot be taken as absolute standards for these, although many of the so-called physiologists pretend that such is actually the case, simply because Uor M 100 diseased and healthy conditions are but the different manifestations of uniform life under varying conditions. VIRCHOW, in his recent work, expresses himself ably upon this point. He says:- "Pathology presupposes Physiology; but the mere knowledge of Physiology, is not sufficient, as some persons believe, to explain diseased conditions. I mean in a manner similar to what the (so-called) rationalistic school has attempted to do. "It is not enough to have a Physiological Pathology, free from physiological contradictions in its cxplana- tions, but it is necessary to attain, by self-experience from empirical experiments and observations, a Patho- logical Physiology. I understand hereby a Pathology which teaches the downward course of the phenomena of life; the manifestation of its very laws under unusual pathological conditions. Next, as might be said, to normal Physiology, this Pathological Physiology must develop itself as independently as pathological normal anatomy has done by the side of anatomy; not as an ingenious system-a mere doctrine of possibility, the thought of idle moments but as the slow result of long-continued labour. Then will exist that Pathology of which HALLER said that it enlightened Physiology." Hereby the chief point upon which everything de- pends is exactly indicated. I cannot leave unmentioned, that some followers of this method are particularly proud of using the stethoscope and microscope, and glory in their results as the only certain and reliable ones. None can deny that these instruments have led to many valuable discoveries, and that they ought conse- quently not to be neglected by any practitioner; but it is too partial to consider the results so obtained as the 101 only standard ones, because they only have their certain relative value when combined with the results obtained through other inquiries. Besides this, we find that the results obtained through the stethoscope by several practitioners, differ some- times completely in one and the same case, as post- mortem examinations have proved, so that a very eminent anatomist who had repeatedly made them, considered stethoscopes mere playthings. How careful we must be in accepting the results furnished by the microscope, is taught us by EHREN- BERG in a most striking manner-EHRENBERG, that hero of the microscope, who astonished the entire world, and shook the very foundation of science itself with it. The enormous number of infusory animals discovered by him are considered, by recent investigators, to be but lower alga (aquatic plants), and not animals. The red points, which EHRENBERG took for eyes, are bodies of colour. What he looked upon as the mouth, is but the interior space of cellular tissue. What here occurred to EHRENBERG has happened, and will yet occur to many others; and though we must praise the diligence and perseverance shown in these pursuits, still must we be careful in adopting and making any practical use of the results obtained thereby, and above all, should not be too hasty in draw- ing immediate conclusions and rules from them for practical use. Others of this school chiefly rely upon pathological anatomy, and wish to treat and explain the diseased process of life from the mere throwings off of disease. How foolish this is I have already shown. VIRCHOW says: Be very careful in believing that anatomical 102 As examination of the organs and structures is sufficient to indicate in every instance the seat of disease. little as the anatomist is capable of demonstrating the various sensual organs as the specific seat of sensual influence, without the aid of any other means of investi- gation than is offered to him by his science, so, just as little can the pathological anatomist localise a series of diseased effects, even if they are entirely of a local nature. The localisation of disease can only be partly fathomed by anatomy. The pathology of the nerves is least of all approachable to anatomical research." But I add, that it plays a main part in the diseased conditions, both as regards their knowledge and treat- ment. More recent and enlightened practitioners share this conviction; and begin to seek for pathological examples, instead of the specific pathological forms of tissue and peculiar pathological chemical bodies, which but a short time ago were, and in some instances are still looked upon, as models of medical wisdom, to obtain gradually a knowledge of physiological examples, endeavours which deserve our utmost praise and encouragement. Listen to what VIRCHOW in- geniously says: "Life realises itself in every point according to the local possibilities, and may, therefore, reveal itself differently at different times in the same smallest organic part, in the same separate cell. If in any part of the body under diseased conditions possibilities appear which are realised otherwise in other parts; if materials are deposited and accumulated at certain parts, which should only occur in other places, so can the phenomena of life in the diseased parts 103 adopt forms which, it is true, are qualitatively different from those which belong to these points, but com- pletely agree with the forms appearing in other parts. This explains the error loci of substance. In this manner, we obtain certain physiological types for pathological occurrences, yet so that a local difference always exists between both, and that the normal course in loco is, as it were, substituted by a qualita- tively different one. Life, therefore, obtains no new forms specific and peculiar to the course of disease, but only a new locality for an existing form.” That which is general should, therefore, not be con- founded with that which is particular. Urea is secreted by the mucous membrane of the tractus digestatus, and not by the kidneys. The diseased processes vary in quantity and quality from the normal processes of the part. Here is another example:- A cancerous or sarcomatous swelling appears in the eye. It develops itself, as it would in every other place, conformably to the laws of life, only that the cells become dotted (melanotic — black-like). This happens because the local direction of the processes of nourishment from the cells of the choroidea which, in a healthy physiological state are of a blackish pigment, transfers itself to the cells of the swelling. No new pathological form of the choroidea is transferred to the swelling, and the physiological state of the choroidea is the physiological model for the pathological con- dition. In recent times the materialists have tried to gain more ground than the advocates of the pathological anatomical direction. You know, from what has been said, how they attempt to trace back the process 104 of life, both in its healthy and diseased state, to mere chemical and physical processes and descriptions of form; how they attempt to explain life from the mere analysis of the conditions of life and its residues, and how they present the organism to us as an inorganic chemistry and mechanism in its products of dissolution; how they entirely overlook the fact that life progresses continually, and not by fits and starts, that it emanates only from motion conveyed without interruption from one member to another, using matter with its chemical and physical (so called) molecular power as means for its own revelation, and employing them in accordance with its own higher organic laws in creating organic forms, to attain organic functions; how they, therefore, mis- take completely the means and the object. But you know, also, that these chemical and phy- sical processes actually precede life, travel along its boundaries, and follow it; that the proceedings of life itself which occur in the interior of the tissues, its actual furnace, have not in the least way whatever. been understood by materialists, nay that they are not even able, in consequence of the numerous divisi- bility of molecules, to indicate the train of possible chemical and physical processes and products, which exist before, next to, and after life, as most bodies, ac- cording to their varying divisibility, possess also different chemical affinities, and, in every part of the body, unforeseen conditions can occur which often open unexpectedly new divisions, with new chemical affinities and products arising therefrom. Here are a few ex- amples of the mobility of the molecules, and of their divisibility. Sugar can be divided into alcohol and carbonic acid, 105 or into lactic acid and water, or into butyric acid, carbonic acid and hydrogen, or into formic acid and acetic acid, or into oxalic acid, carbonic acid and water, or into saccharine-acid and water, or into ulmic acid, carbonic acid and water. Cyanogen can divide itself into cyanic acid and prussic acid, or into car- bonic acid, ammonia and urea, or into oxalic acid and ammonia, or into oxalic acid, carbonic acid, formic acid and urea. This mobility of molecules renders it impossible to state with any certainty which of these divisions will happen. Every one is possible, and can change into another according to the bodies with which it comes into contact. You see, therefore, that materialists are unable whilst experimenting with sugar to state the chemical divisions, much less the changes which occur by taking it in the organic tissues, things of the greatest importance for an organic biology, and that their analysis of the secretions and residues must vary as the one or other division happens. For it is truly not indifferent whether alcohol or lactic acid, butyric or formic acid, or acetic acid or oxalic acid, or ulmic acid, etc., develops itself in the organism after partaking of sugar, nor if after having taken cyanogen, whether cyanic acid, prussic acid, ammonia or urea, or oxalic acid, etc., is secreted, as the organism is affected hereby in the most varying manner, and that therefore quite different modes of treatment must of necessity follow, which materialists are totally unable to indicate. And what do they gain through their analysis? At the utmost only the sum total of the component parts which life consumes in the formation and un- doing of its structures, without being even capable of indicating the possible physical and chemical combina- 106 tions which this matter has passed through before life, whilst acompanying it, and after! And yet they have arrogance enough to attempt to read the organic book of life with such an alphabet of matter, which does not even enable them to stammer the physical and chemical sounds. You call him a fool who, having gained only a know- ledge of the twenty-four letters, believes himself to be in possession of their thousands of varying combinations into words, and, consequently, of the contents of clever books. But more foolish are those, who from the results of chemical analysis presume to draw conclusions respect- ing the numerous chemical processes; nay, more, hazard conclusions as to the organic ones, which differ com- pletely from the former! Let them be domineering and presumptive, let them compile indexes on indexes, let them, with the cry, " Numbers prove!" dupe many, and often clever men, yet know that they only prove their own ignorance and want of thought by so doing; that synopses and numbers are but too often made after certain plans to attain the one or other object in view, and that there exist compilers of synopses and numbers, as well as there were formerly (particularly in England) compilers of cases, who, through pretended. cures and descriptions of disease have misled the entire medical world, and that finally the too hasty adoption of such results, even by first-rate medical authorities, proves most strikingly the hollowness and unsettled state of so-called medical science. In their distress, they grasp at every straw, and exult if they fancy they see land in the one or other direction, though it be only a naked and sterile rock, or a barren and sandy descrt. 107 The winds of hypothesis and arbitrary conclusions whirl up clouds of sand, and those who land are actually so blinded that they can neither see nor examine anything. As regards numbers. I have already before said that the application of mere mathematical formules to biology was a silly trick. In the formation of crystals, the movement of molecules is in a straight line, and can therefore be expressed in numbers; but in the organ- isms, on the contrary, it occurs in transcendent curves, and a numerical statement of such is always irrational, and cannot therefore be exact. But every atom has its own importance, as from a single one often depends the formation or non-existence of a body, as chemistry clearly shows to be the case. The theory of the limits of error with which they attempt to cover such deficiencies, must, therefore, be rejected as unscientific. They cannot even fix outward organic form in numbers, how much less then the mani- fold interior structure of the tissues in its constantly alternating transformations. It is, however, not my intention to deny all merit to these endeavours. I already have given you my opinion on the subject, which, please to recall to memory. But we must oppose those who raise chemical analysis above everything else, who see in it the only salva- tion and sole regeneration of medical science. They convert life into death, precipitate living organic form into lifeless inorganic filth and mire, and with their inorganic consequences lead healthy and diseased life to disorganised dissolution. Such men prove most injurious to organic biology, as well as to healthy and diseased life itself. 108 If people wish to test and recompense their clever- ness and assiduity in analysing, let a second ALEXANDER come forward. His great predecessor ordered once that a measure of peas should be given to a man who cleverly threw peas at a great distance through a small opening, and expected a great reward for being able to do so. Let him make them overlookers, nay, even owners of sewers and drains, that they may have plenty of material, which by their clever analysis, they may lead anew into the roads of life. But why thus indignant? Surely they and the position they have so arrogantly assumed are but of short duration! Does not the history of the development of humanity teach us that it causes, at certain times, the dregs and dirt to appear from out its very depths on the surface, so as to get rid of it once for all. We will, therefore, consider these also as forming a necessary part of the purifying process of growing science, and will not envy their enthusiasm in recognising, nay, even in constructing, man, from out secretions and other throwings off. But VIRCHOW expresses himself ably on this mode of considering organic life, and explaining it as the mere result of physical and chemical, and therefore, molecular power. Listen to what he says. "The radicalism which seeks the mechanism of life only in the acting against each other of such molecular powers, which are im- manent in the constituting particles (molecules) of organic clements (cells) is not empirical, and, there- fore, illogical. "Life proceeds not by fits and starts, but pursues its onward course through successive generations. There exists no other life than that by succession, and there 109 must be, besides the power which is constantly bound up with matter, another force, which is transferred from one member to another (this power does not allow of being put together in a mechanical manner). "Whence it came has not been empirically discovered; but this deficiency does not justify us in denying it. We have, therefore, two different powers in the living body—the molecular, and the excited and exciting vital power, the co-operation of which forms the elementary or cellular power by which we, in a more general sense of the word, understand vital power." Moreover: "Vital power regenerates itself out of mole- cular power by means of nourishment. Life depends chiefly upon an inward movement, which arises mostly by latent powers becoming dissolved and brought into action." Further, "Life is within every separate species. bound to fixed typical forms of manifestation. If this inward arrangement of form is so altered that alternate changes occur between matter, as is apparent from the simple action of molecular power, which might occur in each of these parts, even without the existence of life, then life itself is no longer possible. The inward movement, as introduced by vital excitement, can no longer continue-death occurs. Therefore, there exists. in the living body an antagonistic principle between vital power and molecular power of matter-between vitality and chemistry. Life subsists only through the inward movement (vital power), liberating molecular, powers from latent conditions, causing, as it were, a strengthening of vital power, and a kind of renovation of life, so that most of the phenomena of life and disease are caused by molecular powers, but, only in as far as the latter are freed by vital power. All that 110 which exceeds this, is, with reference to the body, dead action." KUTZING, in his Philosophical Botany, follows him very closely, saying, "Life, in its physical meaning, is the relative movement in absolute space, therefore, in that which is not confined to space. "Through this relative space, relative magnitudes are formed. Only these exist physically for us. Absolute magnitude is, therefore, physical nothing; but for this very reason absolute all, from and by which for a time relative space is animated. This animated vacuum is that which has been separated from the absolute, the physical separation from God, but not the spiritual. For God's spirit, boundless and infinite, works every- where, as the moving law, as the animating being, as a continual force. The primum movens, the abso- lute, is extramundane. It only reveals itself in phe- nomena as worldly principle, without entering itself as absolute in the manifestations. The mundane soul, on the contrary, is but an abstract of that which is physical, and has nature as its presupposition." We have now pretty well reviewed the physiological method in all its representatives. You see it shares the same fate as the antipathic and revulsive methods, it is brittle and rotten, like them. A true and animated description thereof, HERSCHEL gives in the following words: "With enthusiasm this anchor of safety (physiology) is seized upon. Young people in particular call themselves with pride the physiological school, and speak of a new era which has sprung up in medicine, giving a totally different and more rational contemplation of disease. But arriving at the treatment, the real mission of medical 111 practitioners, their supposed wisdom and cleverness, forsakes them; they shrug the shoulders, and hide their weakness and ignorance behind embarrassed scepti- cism or dangerous indifference, which leads either to the coarse empirical choice of by no means indifferent remedies, or causes them to abandon the patient to his fate. Of what good is it to humanity if the learned pathologist, possessed of the entire apparatus of recent medical science, shows by auscultation and percussion of the patient to the astonished layman, the very place where the cicatrised tubercle, the emphysematical enlarged cell of the lungs, is situated; if he describes accurately" from the beating of the heart how its valves are affected, if he demonstrates to him the extent of the liver, or if he describes anatomically the history of pneumonia, but as soon as he must act himself sud- denly becomes frivolous, and jeeringly declares the precariousness of medicine, or complains about the impossibility of a cure (or even of mitigation)? If not to go beyond inflammation of the lungs a celebrated and with the physical investigation, particularly familiar diagnostician, adds, after an able description of this disease in the hospital, that it is the same whether you bleed, or give opium, or tartarus stibiatus, or nitrum, or whether you give anything or-nothing at all? or if an enthusiastic professor, a follower of recent medicine, gives expressive orders to those to whom he has entrusted his absent child, not to call in any medical man if it should fall ill? Is such a confession not an acknow- ledgement of the impotency and ignorance of Materia Medica and the art of healing? If nature cures, of what use are then all the treasures of medicine, and the so 112 highly extolled pathological knowledge? If therapeutics, the real art of curing, be rejected, why not do the same with pathology, which has reference to disease? Or is the physician only there to examine nature, note down her manifestation, and to wonder at her many vital energies? Should he rather not learn from her to act independently? This far niente will never be approved of by the more intelligent followers of the old thera- peutic school. WUNDERLICH, in his Pathological and Therapeutic Manual, calls the contempt of therapeutics a deplorable mistake; and with as much truth as dignity, he adds: "If, in nearly all forms of diseases, a number of cases. recover without the medical assistance of a physician, and others are lost in spite of all medical endeavours, there still remains a considerable third proportion of cases. where a judicious medical treatment is decidedly bene- ficial. It is also a very narrow conception of medical performance to believe its only mission to be the restor- ation of health. The abbreviation of suffering, the removing and alleviation of complaints, the relief and rendering certain diseased conditions endurable, the protection against threatening dangers, are as serious and worthy exertions of the physician." But what do we profit from these therapeutics as long as they continue the beaten track? Of what service have been to it all anatomical, physiological, and pathological results? We might quote thousands of examples, that the present mode of treatment is still the old, coarse, empirical one; and that even the cleverest physiologists are subject to it, is proved to us by WUNDERLICH's own directions. So he says, whilst alluding to the treatment of the 113 forms of irritation, "Except the causal treatment, a double mode of proceeding is applicable to many of them: either a slow and prudent mode of treatment and attendance, or a bold one, with large doses of powerful medicines, in particular narcotic and metallic remedies, intense cold, copious general or local bleeding, and strong counter-irritants. "Although these methods are not without audacity and danger, yet on them the quick and good result of certain cures depend, in which irritation needs not be the chief momentum. Which of these two me- thods offers the best chance of recovery cannot well be predicted. Often, a disease which has resisted the greatest care for a length of time is cured in a few days by such heroic treatment; in other cases, on the contrary, the harm done to the patient by such a treatment can never, or only in a long time, be repaired." (It is truly sad, if the patients' life and health are risked upon two cards, only, the one of which is doing almost nothing at all, the other, on the contrary, a hazard game, which bears as motto: If it succeeds, it is well, if not -not!) "In a similar manner, WUNDERLICH advises a bold and energetic treatment of acute complaints where the symp- toms keep constantly increasing, as if this alone were sufficient. His real treatment, however, is the antiphlo- gistic one, moving only just as BROWN, between the two extremes of sthenic and asthenic. If the disease approached the highest point, let it be remembered that at this period the process of disease is no longer accessible to direct therapeutics, but that the chief danger here also depends upon the accessory circum- I 114 stances (therefore symptomatic treatment). Only - exceptionally-by very decided essential indication, can adherence to the former save from destruction (there- fore direct therapeutics still possible). In chronic diseases, he allows great scope to the symptomatic indication next to the direct mode of treatment." So far HIRSCHEL. Under existing circumstances, we need not wonder that many conscientious physicians start back from the chasm which opens itself before them, as soon as, in their real task of life, they have to practice that which they have learnt. Like many other physicians, WUNDERLICH expresses himself in bitter and sarcastic terms about the hollowness and danger of general therapeutics; he says: "It certainly cannot be denied that the want of a solid basis, a sure ground of immovable everlasting facts is felt in no other branch of medical science so acutely as in gencral therapeutics. Instead of observations, we only meet everywhere with flighty remarks; instead of proved principles, mere suppositions; instead of clear conclusions, dogmatic rules; instead of descriptions of effects, useless definitions and transmitted categories. The very isolated handling of general therapeutics has proved destructive to the same. the meagre positive contents, could not even fill up the most mode- rate boundaries of a self-dependent discipline. • Aud in spite of this better, though negative under- standing, he, in his own therapeutics, cannot extricate himself from the labyrinth into which he has strayed, because in it, as well as in others, organic unity has been torn to pieces, and no organic pathology, nor physio- logical Materia Medica, nor organic therapeutics are to be found. 115 Others, in their scientific pride, consider themselves perfect in everything, and, above all, will here call my attention to the theory of inflammation, as an exact and, in itself, completed theory. But of this we will speak in our next. 116 LETTER VIII. INFLAMMATION.-THEORIES AND TREAT- MENT OF THE SAME.-THE TRUE SCIENCE. THE doctrine of inflammation is undoubtedly the best and most complete of all therapeutics. Let us see what it offers to us, and we may then easily infer what we can and may expect of the less good and more incomplete ones. The contemplation of the separate case will give us a livelier picture of the theoretical and practical doings of medical men up to the present moment. Formerly, redness, heat, pain and swelling were looked upon as the characteristic symptoms of inflammation. Pathological anatomy, however, be- coming extended and developed, this group of symptoms was allowed to drop, and in the French school the flush, in the Vienna school the exudation, became the prin- cipal symptom; but this also was soon considered without validity. The more facts became known, the more exactly and carefully these were inquired into, the greater became the difficulty to fix the definition of inflammation. 117 Through the theory of stase, which means the stagna- tion of blood in the capillary vessels, it was thought the riddle had at last been solved. With the microscope, such a stagnation (stase) had been observed in the capil- lary vessels of frogs, and combined with the anatomical and chemical results of the analysis of exudation, was at once formed into a theory of inflammation, without anybody having given himself the trouble to prove the actual stagnation of the blood, or its possibility, in inflammation happening in the human body-assuredly a very dubious proceeding! This stagnation was said, according to the theory of paralysis, to be caused by extension of the arteries; after the spasmodic theory, by their contraction. But con- tinual observation soon proved, that neither extension nor contraction of the vessels was a constantly proved phenomenon of inflammation. Complete stase occurs generally only in amphibious animals, less so in bats; and in men we are quite unable to consider it a regular appendage of inflammation. In dead bodies, we do not find those changes of the blood globules at the source of inflammation, which experimenters describe as having been observed in frogs. Moreover, we find in physiological hyperemics quite the same conditions of the blood as in pathological ones; nor can any continual exudation take place in vessels where the blood is stagnant. We often see real stases forming themselves where no inflammation exists. If a stagnation happens in an inflamed part, it is often the result of the pressure which the exudative or growing-up accumulation of inflamma- tory products causes in the vessels. THOMSON says, that the circulation of the blood 118 can be either reduced or increased during the entire time inflammation lasts, so that the stase is no abso- lute or necessary manifestation of inflammation. The manifestations of stase can be produced by inflammatory irritation even where the circulation has been stopped. H. WEBER saw, on underbinding the supplying and leading-off vessels, and applying diluted caustic potash, hot water, and moderately diluted acetic acid, that the blood globules accumulated in the same manner as in stase. The blood, then, not only circulates from the arteries into the veins, but that of the veins returns in a backward direction. If the circulation is re-established, the stase remains. The so arisen stase is dissolved, after freeing the circulation by satiated solutions of sugar, blood-lye (blutlauge), and sulphate of magnesia, whereas these solutions produce in primary free circulation, congestions, viz. accumulation of blood globules, with a retarding of the current. After all this, the theory of stase falls together as in itself unten- able. Others, and in particular (as I have already said before) the Vienna school, looked upon exudation as the main sign of inflammation, and completed the theory of exudation. According to it, the inward and outward irritants touched the sensitive nerves, in consequence of which, antagonistically vascular nerves became para- lysed. Thus the paralysed capillary vessels were extended through the blood, through this the coats. became thinner, and the passing through of liquids. rendered the easier. HENLE was a great supporter of this view. But through extension the current is quickened, and cxu- dation prevented; the most considerable extension. happens often without exudation. 119 In vascular parts, where an extension of the vessels is entirely out of the question, the exudation occurs at the irritated place not at the nearest adjoining vessels, as can be observed on the horny tunicle (sclerotic coat) of the eye. The theory of exudation cannot, therefore, be considered as the essence of inflammation. Others again, considered inflammation to be an increase of fibrine in the blood. ANDRAL and CHAVARRET may be indicated as the founders of this theory. An isomeric soluble fibrine is presupposed to exist in the blood previous to the insoluble one found in the product of inflammation, without having furnished the proof for the latter. A second error is, that of uniting too often one's remarks to the product found. A third, that in the usual analysis of the blood, the time of coagulation has, in most cases, not been considered, but that merely the result of coagulation has been taken up in its totality, and that thus higher and lower products are thrown together. The increase of fibrine cannot, moreover, be considered as the basis of inflammation, as similar conditions are met with in other, even in physio- logical, processes, e. g. during pregnancy, in horses, etc. Whence this change in the mixture of the blood arises has not yet been ascertained. Some consider fibrine as the product of the cast-off muscular substance (muskelmauser); others, on the con- trary, as the real plastic matter sprung up from the progressive metamorphosis of albuminates. VIRCHOW considers it the sign of distributed inflammatory distur- bance over the lymph vessels. The increase of the row of fibrine is an effect of inflammation, but not a specific one only peculiar to it. This increase does not alone occur in pregnancy, but 120 in pregnancy, it can also be produced by the abstrac- tion of blood, in particular, by venesection. Besides, it often occurs in many disturbances of no inflam- matory nature, and, in many cases of inflammation, it was not found, as NASSE has shown. The theory of fibrine shares therefore the fate of the others. A very cleverly completed theory is that of attraction. It rests upon the attraction between blood, vascular coat, and parenchyme. According to its vital conditions, the permeable capillary membrane is as a living skin, and not only from its structural and elastic proportions, of very differing value in the exchange of matter between blood and the humours of the tissues, but it may promote and impede it. On the other hand, this exchange is very dependent upon the chemical and mechanical constitution, and the degrees of pressure of the blood, and of the textural humours. A certain condition of concentration and contents of fibrine of the blood are normal conditions of capillary circulation; a dissoluted defibrined blood causes impediments. The measure of attraction between the vascular coat and the blood, is of very important moment in capillary circulation. The peripheric (plasmatic, lymphatic, slow) layer, with the colourless blood globules, moves. slower than the central part of the current with the red bodies, because they are kept near the coat by molecular attraction. Therefore every remedy which increases this attraction, must determine the entire current. Of the highest importance is also the inward cohesion. of the serum itself, which differs in the liquor sanguinis, from that of the blood globules, whose proportion of attraction is chiefly determined by form. Normally, they lay their flat surfaces together to the 121 well-known piles of money, and that often with wonderful rapidity. If they lose their coiny and flat shape, then the degree of attraction changes also, and becomes each time less. The natural attraction of blood-corpuscles among each other, contributes materially towards the normal degree of circulation. Moreover, does every blood globule possess a certain degree of attraction towards a certain quantity of plasma. Every change in the density of plasma changes the blood globules, and so diminishes the inward cohesion, which manifests itself finally in a dissipation of the central red current The more the inward cohesion, the easier the blood flows into the capillary vessels; the greater the mole- cular attraction towards the coat with lessened cohesion, the easier the accumulation. Upon this the theory of attraction is chiefly based. The circulatory distur- bance is always the secondary, never the primary cause of inflammatory local suffering. Through this theory, therefore, stase, but not inflammation, may be explained; and it is, consequently, insufficient. The neuropathologists maintain, that the irritation of sensitive nerves is the constant starting point of inflam- mation, and the antagonistic paralysis of sympathetic vascular nerves the next cause thereof. Inflammation, however, can be as well produced with as without nerves, as BIDDER, WHARTON JONES, H. WEBER, and LEBERT demonstrate. Hereby it results that the appearances of irritation, not only must be attributed to the nerves, but also many of them must be attributed to the other elements of vitality. Therefore, the irritation of the textural parts themselves only is considered as the actual beginning of inflammation. But the richer a textural part is in sensitive nerves and blood-vessels, the quicker 122 this change will extend itself, and irritation gain the height of inflammation. Thus there is between irrita- tion and inflammation but a quantitive difference. The phenomena of irritation have generally a more functional dynamic character, because the finer transpositions of matter from which they arise are often unapproachable, either to the armed eye or to chemical analysis. Pain, muscular contraction, and relaxation are essential func- tional disturbances. If the disturbance adopts gradually a coarse material anatomical impression, then inflamma- tion commences. The textural parts of the furnace of inflammation change their inward constitution, and from the changed cohesion new chemical and morphologic combinations result. The inflammatory redness has its origin in a gradual increasing extension of the total nutritive vascular apparatus of the part, and in a rela- tive augmentation of the blood-globules in the capillary stream-current, which had been altered by the changed degrees of textural attraction. Next to the nutritive disturbance, the functional disturbance of sensation movement, secretion, etc., remains one of the most important symptoms of inflammation. As long as through an irritation only functional disturbances are apparent, it is usual to call it irritation, but do nutritive disturbances occur, then it is called inflam- mation. During the later course of inflammation, a part of the irritation-phenomena continues to exist, and the more perceptible, the more abundant the affected part is in vessels and nerves. The quickness and bulkiness of the transposition of matter happening in the tissues them- selves, indicate the inflammatory process. The changes of the tissues are more of a chemical 123 regressive, or histologic progressive kind. It has been already shown that neither the increase of fibrine in the blood, nor the exudation nor the heat or the pain, nor the vascular enlargement, can be looked upon as specific signs of inflammation, but that the local changes of circulation were insufficient to define inflam mation. It can only be considered as a nutritive disturb- ance distinguished by the magnitude of its performance, by the quickness of its course, but chiefly by the character of danger. This process of inflammation has as many possibilities as there are different forms of nutritive disturbance of the separate parts. The defini- tion of chronic inflammation is elastic and difficult. The process does not always run on in the same manner, but, from the very commencement, the one or other side may come forward in a stronger manner, such as pain, redness, swelling, etc. The first development of inflam- mation shows itself in different ways, according to the close relation of the nove to the one or other element. Next to this different kind of irritation, it is in par- ticular the pathological predisposition of the part which determines the series of ailments and the disease itself. This predisposition can be local or general (dyscratic), In the latter, we find, in many cases, foreign hete- rologous substances to the body, deposited in the very furnace of inflammation, which give a peculiar character to the further course of disease. Inflammation differs by its destructive tendency from the usual process of nutrition, but, in accordance with its real nature, it is only a local disturbance of nutrition, and depends, like all local processes of nutrition, upon the alternate proportional change between blood and blood and tissues. VIRCHOW has worked out with particular predilection 124 this theory of inflammation, as a disturbance of nutri- tion, and giving a definition instead of a description, he believes himself to be no longer on the symptomatic path, but on that of generative investigation. However ingeniously this theory has been formed, the acknowledgement alone, that, according to it, the defini- tion of chronic inflammation is a difficult and elastic one, indicates its insufficiency completely. Nor will it last long ere quite new ones of less apparent validity, and apparently more extensive actual confirmation, will appear to be carried very quickly by Charon's boat to the other shadow theories in the lower regions. And yet it is true, that no chapter of pathology has been worked out more carefully, and rendered more distinct and intelligible than this; it is true, that the pathogenesis of inflammation is one of the most com- plete ones we possess! And what has it offered to you? Theories over and again, exactly like the other chapters of pathology, only that they contain less facts, and are more unsubstantial. Whereas, in the doctrine of inflam- mation, chief attention has been paid for support to physiological and pathological facts, and thus an im- portant step ahead, an advance has been made. But how stands it with the treatment of inflamma- tion, after all these and in many instances ingenious theories? Here again the old practice of throwing several indications together, is followed up. The causal indication and the indicatio morbi are quoted; through the latter, the process itself is to be kept within boundaries. For this the antiphlogistic method, with bleeding and cupping, together with the revulsive method with rubeficantia and vesicantia, inward narcotic remedies and antiphlogistic salts are recommended, and 125 finally they mention hydrotherapeutics. It must astound every one that sanitary gymnastics were forgotten. If so, all methods would, at all events, have duly figured upon paper. Thus, instead of a single organic indication, by which the separate directions necessarily develop themselves from out a single mutual germ, and thus correspond with the organic picture of disease, which was created in a like manner, we have again an arbitrary patchwork of parts which have been taken away from their organic associations. And it is VIRCHOW who does this! VIRCHOW is not ashamed of prescribing, after the old jog-trot way, narcotic remedies, and antiphlogistic salts, quite according to the old empirical way, which (being without method and criticism) he rejects himself; he who only recognises the experimental empirical mode, as authorised, and who continues further:-"What we require to know is, what changes a remedy produces under changed vital conditions in the body. This we learn from the changes, which a certain remedy under otherwise normal vital conditions, produces in the processes of life;"-therefore, by means of physiological examination. Thus, in spite of this acknowledgement of the necessity of physiological examination, VIRCHOW recommends these remedies without a physiological examination, after the old empirical method, which he condemns himself! It is true, he does not seem quite at his ease whilst speaking of antiphlogistic salts, for he says that the alterations which they are said to cause in the blood are not quite established, in particular the antiphlogistic effect, viz. :- diminishment of fibrine, which has been so repeatedly attributed to them. Ought not VIRCHOW, first of all, 126 to have made physiological experiments, or if he could not have done so, should he not then have abstained, for the benefit of suffering humanity at large, from actually re-organising a method which he had condemned him- self, and, thereby, propagate knowingly its errors, and the mishaps arising therefrom. Truly the medical counsellor, TRINKS, is correct in saying, "We must believe that we fall from the clouds, when, carried away by the often ingenious speculations of a practitioner, we find ourselves suddenly among leeches, purgatives, and sudorifics, and see how the most intellectual representation and explanation gocs. down in such mire. If men of such excellent mental power act in this manner, can we be astonished at it if medical men of a lower order, with their mixtures and methods, arc com- mitting worse ravages in the valleys and on the moun- tains than pestilence itself? If VIRCHOW had con- sulted the physiological examination of narcotic and antiphlogistic remedies, he would undoubtedly have made equally excellent remarks about their application, as he did about the abstraction of blood. His words cannot be often enough repcated to those practitioners who are ever anxious to bleed, that they may finally renounce this unnatural vampyrism, I therefore herc give them to you. As secondary changes of sanguinal mixture hap- pening after venesection, we may designate- 1. Increase of the watery, diminution of the solid, component parts (diminution of the specific weight). 2. Increase of fibrine and of the colourless bodies. 3. Diminution of the blood-globules and of albumen. 127 From this combination, it is easily apparent how foolishly those practitioners have acted, who, from the thickness and density of the buffy coat, drew the indication whether they ought to continue bleeding or not, as by each bleeding they diminished the blood-globules, and the specific weight of the serum, and augmented the fibrine matter, and by so doing increased the conditions required for the formation of the buffy coat; nay, often created the enemy they were anxious to combat. It may, on the contrary, serve as a leading principle that until now no fact is known which might justify new bleeding, from any condition of the blood drawn in inflammatory disease. On the contrary, numerous facts are known, which prove clearly the injurious and dangerous influence of bleeding, in particular if repeated often. Not seldom do we witness excessive debility, slow convalescence, lasting disturbance of nutrition, anæmia, dropsy, marasmus, and similar evil effects as the con- sequence of ill-advised bleeding; and it may certainly be designated as one of the most important tasks of the conscientious doctor to be as sparing as possible with the noblest liquid of the body. It may be considered as a general rule that in weak, debilitated individuals, therefore, chiefly in asthenic inflammations, general bleeding must be avoided as much as possible. Several years ago, Dr. WILLIAM ARNOLD expressed himself very ably on the subject: "Medical men resort to gencral bleeding in inflammation, because they are of opinion that by so doing they diminish the quantity, particularly the fibrine matter, of the blood, and lower the action of the heart and vascular system, and thereby the temperature of the body." Against this we have to say, that a general increase of the quantity of the blood is no actual and essential 128 condition or result of inflammation, but that this may occur in individuals who have too little blood. Practitioners who draw blood from their patients. suffering from inflammation, in the idea that they de- crease the fibrine matter of the blood by so doing, follow a supposition, which is arbitrary, in two instances. First of all, au increase of fibrine matter cannot be considered as an essential real symptom of inflamma- tion, much less then a necessary condition of the same. On the other side, no proof has been furnished that bleeding diminishes fibrine. Little or no visible influ- ence on the quantity of fibrine, or a relative increase of the same, has been observed after bleeding. It causes a diminution of blood globules, but less so of albumen; the amount of fibrine is not changed by it; it remains as it was before, that is to say, under the influence of the disease (ANDRAL, GAVARRETS, BECQUEREL, RODIER, and others). Neither can those who bleed in inflam- matory diseases, with the idea of lowering the action of the heart and vascular system, call facts to support them. Experience shows quite the contrary. Very often do we see how, after bleeding, the storm awakes in the vascular system, and increases after repeated blood- letting. The same may be said of the task of reducing the temperature of the body, and so diminishing the feverish heat combined with the inflammation. NASSE proved by experiments, that diminishing the blood does not reduce its heat, but that it rather increases it for a certain time. This increase does not last until the loss of blood is replaced, but in all likelihood only until the quickening of respiration and circulation returns. Unbiassed observations and experiments prove to us, 129 therefore, that the indications which have served, and still serve, as rules for bleeding in inflammation, have no scientific foundation. Besides this, do the clinical hospitals not show to us, that bleeding does not produce the object which is sought to be obtained by it. Several practitioners proved empirically that the result in the treatment of inflammatory disease without bleeding, was a more favourable one than that where bleeding had been resorted to. Thus DIETL's experience is all in favour of the dietetic treatment of Pneumonia, and opposed to bleeding. In a simi- lar manner, Dr. COPEMANN, KRÜGER HANSEN, M. HALL, BURROWES, BROWNE, PEREIRA, PELLETIER, have spoken about the evil effects of bleeding, and have stated clinical facts to support their opinion. M. HALL, in particular, draws attention to the disturbed functions of the brain, such as in delirium, convulsions, lethargy, etc. Dr. COPEMANN alludes to the bad effects resulting from bleeding in apoplexy. He says: "These clinical facts show, that bleeding in apoplexy is so ineffectual a remedy, that it scarcely de- serves to be called one; that the treatment without bleeding is the most successful, that the mortality increased in proportion to the repeated letting of blood; the greater the loss of blood, the greater the mortality." The But the comments and warnings of such honourable men proved always a voice in the wilderness. majority of practitioners took, as usual, to their lancets, cupping glasses, etc. Only in more recent times, it seems as if some light would penetrate in this utter darkness. You see that also the best chapter of Therapeutics is very imperfect both in theory and practice. Everywhere we meet either with hypotheses and suppositions or with K 130 a few facts interwoven with supposition and arbitrary theories, which have been obtruded as laws upon nature, in such a manner, that in them hardly a trace is left of pure objective fact, and of the laws of nature, which can only be ascertained by experiment, and not in- vented by means of mere speculation. Everywhere we meet with the scattered, one-sided conception of uni- form, organic nature, as a few single striking symptoms, or a single organ or system, or striking material dis- turbances, dead products of disease, or offal, which have been made the object of observation, and of treatment, losing sight by so doing of healthy and diseased life as a unity. Everywhere we find the same unfortunate endeavour to make out the inward cause of healthy and diseased life, instead of observing attentively their manifestations, and determining the laws by which they are governed; everywhere we observe the same unavoidable failure in this unnatural attempt, and the resigned idleness resulting therefrom, or the saddest symptomatic treatment, degenerating into the most disgraceful empiricism! And these gentlemen who explain healthy and diseased life after their own arbitrary theory, who, after an equally arbitrary theory, endow the remedies with certain powers, attach these two good natured draught oxen to their supposed scientific cart, and drive often at a furious rate with the property of humanity which has been entrusted to them. And whither are they driving?-where fallacy and supposition always led men to the cemetery. These gentlemen call themselves rational practitioners-they, who, trusting to the infallibility of their own understanding, have, as a rule of conduct, taken theory instead of experience, 131 and the invented and devised laws of their own, instead of the laws of nature. Truly, no common amount of arrogance is required for such a mode of proceeding, which, in some of them, must be deplored as egotistical infatuation, but cannot be branded enough in others as intentional deception. If these gentlemen would but consider that it is neither their opinions nor conclusions, but that facts alone, these answers of nature, decide the practical value of rationality, and that only that physician de- serves to be called rational who recognises the laws revealed as it were by nature itself, and makes them a rule for his future conduct! What is their entire so-called rational medicine but an optional arbitrary embellishment of empirical material, with chemical, physical, or dynamic theories? And what is more natural than that the physician must err in propor- tion as he adheres scrupulously to them, because he follows a proceeding which is entirely contrary to organic nature, and that the patient fares the worse the more rational the physician is in this sense of the word. Experience proves this sufficiently, and many patients are afraid of such a rational speculating practitioner. Nay many even maintain that this rationality is morc derived from rations, instead of from ratio. Truly they are not far wrong, if we consider the real horse-rations of medicines which these gentlemen prescribe. Such rationality naturally cannot produce science. That which they would make you consider as such, is nothing else but a more or less fine-spun web of suppositions and hypotheses, nay even of the most hazardous crea- tions of imagination, and must, therefore, as I have already said, be called, theory of supposition and of 132 hypothesis, as they make us acquainted with the non- sensical conclusions of their preachers, but not with pure objective life and its laws. Thence also the danger in practice, so that the illus- trious BOERHAAVE said—“ Lucky the doctor who does no positive harm," and JÖRG, That the beginner in practice was frequently animated to a quite opposed mode of pro- ceeding by the different writings and theories, because professors more often spoke of their individual views than of those of real science; and SCHULTZ says, that human health was left to the mercy of the doctor's opinion, to his practical or unpractical old inorganic book- learning, or to the chance of whether he hit the right remedy or not; and TRINKS, that this so-called science is against all understanding and nature, and therefore carries the germ of death within itself, and that its complete downfall would happen in the surest and quickest manner through the every-day more and more apparent difference between theory and practice ;, and that real science and suffering humanity could only profit by its fall. This cannot be too often and too energetically expressed. As the error of this general view, and the hurtful consequences of this extensive medical ill- treatment is proved, it is our duty to make it known to the public, that the careless may stand still and the wiser ones be forced to think. Real medical science can only be obtained, like all other natural sciences, by empirical experiments. Through them only we become acquainted with the pure laws of life, which alone deserve to be recognised, as they remain the same and stand and fall with nature: not so with our views, which vary as much as does the mental development of man. 133 Medical knowledge possesses only that value which it appropriates to itself step by step in the field of practice. Behind locked doors, at the desk, books are riddles which the mind explains in its own way, and satisfies itself with an opinion, whether it be the true interpretation of the hieroglyphs or not. Such opinions and hieroglyphs must, once for all, be banished from medical science, as they have been the rock on which organic development has always been wrecked. Life must in the manner above indicated be considered organically, attentively, internally, and ex- ternally, not torn to fragments and divided into blood, nerves, and tissues, with all their manifestations of formation and dissolution; the same must be done with the physical processes which accompany life, together with the conditions necessary to life, and the residues of life, always led and convinced by facts, and from the picture of nature so obtained, the laws must be selected, and this must occur in the theory of healthy life-physiology; in the theory of diseased life—pathology; and in-Materia Medica―the theory of life under abnormal conditions, which we produce knowingly and intentionally. These theories must only be measured each with its own standard, because they are the different revelations of single uniform life, and cannot therefore act in a determining manner, the one for the other, as has been unfortunately the case before, physiology being considered too often absolutely determining for pathology and Materia Medica. Thus they arrange themselves conform- ably to nature, to single uniform life, from which they receive their laws. The different disciplines carried by organic unity, and explaining each other mutually, form the true organic science of medicine, and they stand to the 134 entire as the different organs and systems do to the organism, appearing as its scientific portrait in its mani- fold manifestations. Such a science develops itself out of one organic vital germ, embraces its entire organisation in its organic connexion, and acquainting us with the real laws and revelations of life, teaches us at the same time the means both to maintain healthy life, as well as to lead diseased life, that which is under abnormal condi- tions, back to healthy life under normal conditions; it becomes, therefore, the true mode of cure, the highest and noblest task of the physician. And this science is not a loose one, wafted to and fro by the winds of opinion and supposition. It is through its organic unity, notwithstanding the greatest manifold- ness, as firm and unchanged as nature itself, from which it derived its unswerving laws. In it all medical men agree, because the reign of supposition has been replaced by that of facts, and all, animated by organic blood, work actively in completing science and the art of healing, for their own benefit and that of humanity in general. To get such a science recognised and spread over the world is undoubtedly a noble problem of the age: let us use our utmost energy to solve it. It is deserving of the labour of honourable men, and humanity will not refuse the laurel to the brave combatants who battle for truth and enlightenment. SECOND "POSITIVE" PART. LETTER IX. DISCOVERY OF THE HOMEOPATHIC LAW OF CURE — RULES FOR EXPERIMENT. It was in the year 1790, that HAHNEMANN, whilst trans- lating CULLEN's Materia Medica, and dissatisfied with the numerous explanations given of the action of Cinchona (quinquina), conceived the idea that Cinchona cured intermittent fever, because it possessed the power of producing a like fever in sensitive, though otherwise healthy, persons. He immediately tried the experiment upon himself; and the result of it was, that repeated doses of the decoction of Peruvian bark produced feverish symptoms in him, which bore the greatest resemblance to those of a peculiar kind of intermittent fever. Encouraged by this, he experimented with various other remedies, and discovered the great truth, that the curative property of every drug depends upon its having the power of producing a succession of symptoms in the healthy organism, completely resembling those of the disease. Long before this, he had severely commented upon the different modes of treatment laid down in the Materia Medica, based, as they were, upon traditions, chance, conclusions from analogy, form, colour, taste, 138 and chemical combinations of remedies, etc. The more experienced physicians had already preceded him herein, they also had openly proclaimed their distrust of the Materia Medica. See here what the illustrious HALLER says on the subject: "Above all, it is necessary that remedies should be tried upon the healthy body without any admixture; their smell and taste should, first of all, be ascertained, then a small dose should be taken, and the changes observed, such as the effect on the pulse, on the heat of the body, on respiration, on the secretions, etc., only then, led by the effects produced in the healthy body, they are to be tried on the sick." He remained, however, in spite of his great renown, a mere preacher in the desert. Before him, WILLIAM ALEXANDER had published the effects produced by certain remedies in the healthy body; but they were lost, and found no followers. Such was the chaotic confusion of the Materia Medica, until the bright thought alluded to before, was conceived by the illustrious HAHNEMANN; and the immediately following experiments proved that the egg of Columbus. had been found, and that the first step, necessary towards reform, had been taken. He, with indefatigable zeal, and equally great sagacity, realised the knowledge of the postulate of intellect, of all that which was outside in relation to our healthy organism. By these means, he caused medicinal properties to be no longer dependent upon chance; everywhere he advocates assiduous dis- covery, but does not mean, thereby, experiments upon patients, which he most justly calls a foolishly hazardous game. Everywhere he insists, that the pure effects of drugs should be ascertained, as the only means to obtain a true knowledge of their action; and to effect this no 139 other course is left to us, but to try the medicines upon the healthy human body. Hereby the rule is asked of nature, and this must be looked upon as the very basis of Materia Medica. HAHNEMANN continually endeavoured to ascertain the pure effects of drugs, under what mani- festations and conditions the medicinal effects occurred, what association with certain systems and organs hap- pened, which organs were disturbed or modified by them, which nerves were chiefly deadened or excited, how it affected the mind, what influence it had upon the secretions, how the muscular fibres were modified by it, how long its action lasted, and what was the best antidote against it. Having thus carried out what was considered a desi- deratum, viz. to try drugs on the healthy human body, and having made it a law for himself, to be as impartial as possible whilst so doing, to simplify the diet, to observe carefully the different changes, the outward circumstances, the seasons of the year, the changes of the weather, the temperature, the position, repose, and movement, etc., he had, conformably with the now valid and solely correct development of natural sciences, introduced extensive experiments into Materia Medica, and therefore given a place to the exact method in the inexact Materia Medica, and has thus found the treasure of ascertaining the positive effects of drugs upon the healthy organism of man, creating, in one word, a physiological Materia Medica. Astonished and pleased with these results, he then, with the so tried drugs, put the second question to the diseased human organism; and the answer to this counter-experiment was: To cure the disease in a pleasant, quick, and certain manner, choose that remedy 140 which possesses in its positive, constant, and peculiar effects on the healthy organism, the greatest possible similarity with the main (pathognomonic) symptoms of the disease. Thus, the thought which struck him, whilst reading the different explanations given of the action of Peruvian bark, became an undeniable and indisputable fact, through repeated experiment on the healthy body, followed by counter-experiments on patients, becoming as it were the key of no longer giving medicines after their mere supposed, but in accordance with their real, effects; the leading principle expressed by the words, "Similia similibus curantur," Like is cured by like; from this principle everything else is developed; and physiological remedial experiment can only properly proceed on this basis. All HAHNEMANN's endeavours, therefore, were con- centrated on the one point, namely, to ascertain the real effects of drugs; and he considered repeated ex- periments as the only means to obtain them. Hereby he soon found out that through physiological experi- ments alone the Cimmerian darkness which pervaded the Materia Medica could be changed into the purc light of day. The alterations which medicines pro- duced during these experiments were to be noted down from their very commencement, so as to find out ex- actly what changes they produced in the healthy body. He thus discovered, that the peculiar positive and constant effects of one drug upon the healthy organism vary in as essential a manner from those of any other, as the physical and chemical properties of medicines do the one from each other; nay, that the difference ex- tended to even a greater degree, as substances, though alike in their chemical and physical properties, differ 141 very much in their effects upon the healthy organism. He is quite correct in saying, "So surely as each kind of plant differs from every other sort, by its outward form, its growth and nature, its taste and smell; and that every mineral or salt differs both in its outward and inward physical and chemical properties, so do they also vary in their morbid and curative effects. Each of these substances produces in a different peculiar, though certain, manner, changes in the human organism which render mistake impossible. The peculiar, con- stant, and positive effects of a drug upon the living organism cannot be ascertained from its peculiar phy- sical or chemical properties, nor through its application in disease (as has been explained to you in the first Negative Part), but solely and alone through its action on the organism. But to enable you to form an idea worthy of the subject, it is necessary to enter into some details, in order to show you the rules which HAHNEMANN and his followers observed whilst experimenting, or rather whilst putting their questions as to the human organism, and the manner in which they mentally considered and applied the answers thus obtained to the object of cure. Whilst experimenting, it is absolutely necessary that the persons who do so, should be in perfect health. Those who are naturally disposed for the one or other disease, are unfit for these experiments. Individuality, sex, constitution, temperament, or the being subject to any attack of illness or former ill- health, must be stated as a matter of course. Persons intending to experiment upon themselves, must be able to describe clearly the feelings they experience. It is, therefore, best to choose such persons as 142 are accustomed to self-observation, and possessing sufficient education to describe their sensations accurately. Medical men are particularly fit for this; they enrich science by so doing, develop their power of observation, and strengthen their constitution, as ex- perience has shown. The drug, which is to be taken, must be given in a very simple form, as a powder, or in tincture. Salts and gummy substances must be dis- solved in water. Watery infusions and fresh herbal extracts must be taken immediately after they are pre- pared; if not, they will spoil. Vegetable and mineral acids are diluted with distilled water; nearly all the substances belonging to the mineral kingdom must be triturated with sugar of milk, or they must be dissolved. if possible in some harmless menstruum. Every substance must be taken by itself, pure, with- out any medicinal admixture; no other one must be taken either shortly, before or immediately afterwards, so as to prevent the action of the one from interfering with that of the other. It is, therefore, absolutely necessary that no second remedy should be tried until the effects of the first have completely subsided. In experimenting, the same preparation must always be used. The dose must be sufficiently strong to bring about a change in the constitution, due attention being paid to the susceptibility of the person experimented upon and the quality of the ingredient. If after the first dose nothing of a decided nature is experienced, a double dose may be taken the day after; and, if required, a still stronger one the next; nay even a fourth the day follow- ing. Further repetitions of the medicine will seldom prove necessary, if the doctor and the patient under experiment are attentive from the very beginning. The succession of symptoms shows itself more clearly, aud 143 the result of the experiment is all the more certain, if only one dose is taken; and the duration of medicinal action can also be the more easily ascertained. If, after one dose has been taken, symptoms show themselves, they must be allowed to subside before a second dose should be taken. The lapse of time between them varies. To ascer- tain the effects of a moderately* strong (schwach-kräftigen) medicine, it is advisable to increase the dose every day, nay to take it repeatedly during its course. To ascer- tain medicinal symptoms for chronic diseases, such as skin-eruptions, etc., it is necessary to take repeated doses for several days, sufficiently strong to affect the body. It is advisable to begin the experiments with small doses like those generally used in practice; say one drop of the tincture, etc., and to increase it gradually. On repeating the dose, it should be increased also; whilst taking large quantities of the tincture, care should be taken not to mistake the effects of the spirits of wine for those of the drug. If the symptoms disappear after repeated doses have been taken, it is advisable to return to the smallest dose; and a few days after- wards, you then suddenly administer a large one. here, as in everything else, you must carefully individua- lise and vary your proceedings according to circum- stances. The party under experiment must avoid spices as much as possible in his diet, and abstain from every excess. The diet must be a simple one, moderate and purely nutritious. But All such dietetics which, after undergoing the process of cooking, etc., still retain some medicinal properties, * By moderately strong medicines are understood such medi- cines as are generally considered to be innocent and weak, eg., chamomilla, sambucus, and lycopodium, but which, when indi- cated, prove very strong. - Tr. 144 must therefore be carefully avoided, as their action might counteract the effects of the medicine you experi- ment with, or might prevent the symptoms it has the power of producing from shewing themselves as clearly as they would otherwise do. All drinks having stimu- lating properties, such as beer, spirits of every kind, tea and coffee, are strictly forbidden. All over-excitement either of the body or the mind, all excesses, passions, and exertions should be avoided, as they disturb and interfere with the action of the drug. Should any ex- traordinary circumstance, such as fright, anger, fear, or any outward injury, or excess in the one or other en- joyment, occur, then you are no longer justified in noting down the symptoms as the effects of the medicine you have taken. It is instructive and of practical im- portance to observe the influence of the afore-named incidents; the manner in which they change, increase or decrease the symptoms that have been produced by the medicine, as, not seldom, valuable hints for the administration of the medicine in disease may be ob- tained by so doing. It is necessary, that the person should try the diet which he is to adopt whilst experimenting, before taking any medicine, and to observe himself whilst so living, noting down any symptoms that might show them- selves through this altered regimen. This will prevent him from noting down symptoms which arise merely from imagination; and enable him to ascertain the effect produced on the constitution by abstaining from accustomed stimulants, a thing which is of the highest importance to the person who is going to experiment. The experimenter must know the outward circum- stances which affect his general state of health, such as the influence of the different seasons, the mode of living, 145 the climate, the weather, cold and heat, the dryness and dampness of the air, the electricity of the atmosphere, and the changes of temperature. Changes which are produced by any of the afore-named agents must be strictly separated from the symptoms which arise from the medicine. All the symptoms peculiar to a medicine do not show themselves simultaneously. To ascertain the entire effects which a remedy has the power of producing, repeated experiments must be made, and that upon several persons of different sexes, age, temperament, constitution, etc., so as to discover in each medicine the different modifications in the effects, which are determined by the peculiar physical conditions of the different ages and sexes. It is the more important to experiment upon several persons, as there are some who, notwithstanding their susceptibility to external sensations, are not at all affected by certain remedies. It would be wrong to consider a remedy ineffectual on this account, as so many superficial experimenters or critics have rashly done before. Others, again, are very easily affected by certain ingredients, they possess an idiosyncrasy for particular medicines. This is of practical importance, as these drugs often prove the most curative remedies in the diseases of such persons. The self-experimenter must take the drug upon an empty stomach, and not touch food for a few hours afterwards; or he must take the medicine in the evening on going to bed, and care- fully observe the separate modifications which it pro- duces on the mind, the temperament, and the body, and follow them up in their development. Experi- menters must be allowed, of their own free will, to relate what they observe or have felt, and, if possible, L 146 without having a previous knowledge of what they are to observe. All that has been experienced must be carefully noted down, together with all the accompany- ing circumstances. After having put down everything, the Physician must ask the party to repeat his statement over again, so as to enable him to ascertain how far it corresponds with what he has said before. This is now considered to be positive-variations are rectified. The Physician adds himself whatever he observes. The clearer and more striking symptoms are noted down by the Doctor, stating how many hours elapsed after taking the medicine, and at what time of the day the symp- toms shewed themselves. Those that have appeared repeatedly are put down as decided symptoms; those which are dubious are put down as such until all uncer- tainty has been removed. The symptomatic picture must be pourtrayed according to the combination of the symptoms, their succession, their aggravation, time of duration, and disappearance, stating at the same time whether any former ailings or diseases did re-appear, whether they were increased, ag- gravated, or lessened, or whether they underwent a change for the better, as these contain valuable hints for practice. It is also very important to describe accurately how the effects of a drug appear when the mind and the dif ferent senses are strained, e. g. whilst thinking, reading, writing; during movement and repose; whilst digest- ing, speaking, sneezing, coughing; whilst being in-doors or in the open air; at what time of the day they increase or decrcase; and how they are when in high or in low spirits. The different sensations of pain must be most accur- 147 ately described, sleep also, of what kind it has been, whether accompanied by or free from dreams, of what nature they were, and whether the sleep was refreshing or not; besides this, you must state the changes which the secretions and excretions have undergone in the body, both in a quantitive and qualitive point of view. It is but natural that all these changes which the ingredients produced in the blood, and in the chemical and physical processes which accompany organic life, should be men- tioned as far as lies in our power, and whether they happen in the beginning or at the end of it. Each day the Physician must compare the statement of the party experimented on with his own observations; every day he looks over what had been previously noted down before, and adds that which has become certain. The experiment with every ingredient commences first of all with moderately small doses, then a gradually increas- ed dose is given until the organism is saturated with such a quantity of medicinal power, as will prove sufficient to produce constant lasting and continued effect. The dose should never be given to such extent as to cause serious revolutions in the body, because the different secretions, such as vomiting, purging, perspiring, will again secrete the greater part of the medicine which has been taken, and therefore only a part of its effect becomes apparent, and that in so violent and stormy a manner, that the organic action and development of the drug, are lost. The symptomatic picture of a drug develops itself best of all when small doses have been taken, and the necessary time for their appearance has been allowed. It is, therefore, abso- lutely necessary not to repeat the dose too soon. The experiments must be continued until all further 148 new symptoms cease, and until those which have been observed before show themselves again, so as not to leave the least doubt as regards their reality. The undoubted symptoms produced in the more simple and better described diseases, may also be in- cluded in its symptomatic picture of the drug; but as these symptoms are not easily separated from those which the disease itself engenders it requires great judgment and observation to do so; and it is, therefore, wiser to abandon this difficult task to profounder and closer observers. To complete the symptomatic picture of the drug more particularly towards its material side, we may also avail ourselves of cases of poisoning. The acute ones are of less importance, because the symptoms appear in too stormy and violent a manner prevent- ing anyone from ascertaining the characteristics of the drug. The chronic cases of poisoning are by far more useful, as they often cause clear and distinct changes, both in the forms and structures of which we obtain only slight hints whilst experimenting. For this very reason, experiments upon animals may be useful, if due attention is paid to their own differ- ence of organisation. They possess this advantage that they can be more easily followed up to anatomical and chemical changes. In this manner, however, the coarser deviations only can be ascertained, the physical ones remain entirely hidden. They can, therefore, only be used as a com- pletion of former observations, and should be used with the greatest caution. But for veterinary purposes they are just as necessary as experiments made with drugs on the healthy human body, because, similar to 149 them, they are the sole means of discovering the real effects of drugs upon the animal organism, and there- fore their curative action. Veterinary surgeons have, therefore, the same task as physicians. You see that, in a Materia Medica which has been obtained in this manner, there are no mere suppositions, assertions, or fictions; but that all are the truthful answers of nature to the careful and honest questions which have been put to it; that such a Materia Medica contains the true positive effects of drugs in their totality, both the subjective and objective, the functional and material changes of the structures and mixtures, with due regard to the pro- cesses preceding and accompanying life. If, moreover, you observe the care and exactitude with which these experiments are conducted, the clearness and distinct- ness of the rules, the magnanimous perseverance and self-sacrifice of the experimenters, you will not only be filled with admiration for a man who first set the example and paved the way, but who also furnished much that is excellent; and who, instead of following the weak, uncertain, and deceptive method, by which others formed the Materia Medica, has created the sole method worthy of natural science, viz. — that which is based upon experiment. These rules for experimenting may still be improved, and must keep pace with advancing science; but every extension and completion must bear the mark of experiment; this alone can justify its recognition. Option and hypo- thesis are banished for ever; and in this very justification, through experiment alone, do we find the real greatness of the high-gifted HAHNEMANN, and the natural philosophic inauguration of Homœopathy. 150 HALLER and ALEXANDER, as I have stated to you before, maintained the necessity of these experiments, and a great many others followed their example, and some even undertook them. Thus, ATTALUS PHILO- METOR, king of Pergamus, experimented with poisons and their antidotes upon himself (B.c. 134); MITHRI- DATES EUPATOR experimented upon malefactors; the Arab ABEN GUEFITH, insisted upon these experiments, and the comparison of their effects between animals and men; Conrad, Gesner, FERNELIUS, and, above all, WEPFER and STÖRCK, have given us some valuable con- tributions. FR. HOFFMANN has, in many of his books, drawn attention to the importance of these investiga- tions. STAHL has done this also; and, before them, PARACELSUS. In latter times, MAGENDIE and ORFILA have striven to find out physiological and toxicological facts in men, but even more so in animals. JÖRG, professor in Leipzig, formed an association of experi- menters, and put down the result in a special work of his. He desired, by these experiments upon healthy persons, to ascertain how medicines acted; and he, at the same time, was desirous of proving that HAHNE- MANN's experiments were fallacious. MORITZ MÜLLER, however, actually proved, by a combination of the symptoms experienced by these two experimenters, that they do agree, and that JÖRG's experiments, instead of contradicting those of HAHNEMANN, only confirmed them. Almost simultaneous with JÖRG, VON WEDE- KIND insisted, at a meeting of the German naturalists and medical men in Heidelberg, that drugs should be tried upon persons in health, as he thought it was high time that the Materia Medica should rest upon firmer foundations than hitherto, and that all option 151 should cease; but he only wasted his words. At the meeting in Erlangen, the same subject was broached again, and obtained a sad notoriety by the deplorable swallowing of hepar sulphuris, and colchicum. After- wards, a club of experimenters was formed in Vienna, and the old Materia Medica was severely dealt with. The results have been stated, but through their faultiness they are of no particular value either to science or to practice. Undoubtedly there are but few who have sufficient perseverance and capacity to undertake the severe and careful experiments which HAHNEMANN exacts; this is no doubt the reason why the results are so imperfect, as it is impossible to become a good ex- perimenter in one day. This is also the cause why so many only find out the coarser effects of medicine; the more delicate ones, those which characterise the sphere of action, and which often prove the most important in practice, these remain hidden to them. Nor does it follow, because persons have made chemical and physical observations, that they should also be good observers of organic effects. On the contrary, the eye directed only to the material, though armed with chemical and physical spectacles, is often deceived, so that the more delicate play of organic effects escapes. it. To infer from this that they did not exist, as many have arrogantly asserted, is equivalent to con- stituting yourself the sole law of nature, adding, as it were, the greatest inanity of mind to arrogance. Those, however, who have carefully followed HAHNEMANN's foot- steps, have, by experiments on the healthy body, ma- terially benefited the Materia Medica. Great praise is due to the performances of the Homœopathic Phy- sicians of Vienna, who have published their observa- 152 tions in the Austrian Journal of Homœopathy. The records of the experiments have been printed at the same time, which is of very great importance for de- termining the characteristics of every remedy. These gentlemen have experimented afresh with several remedies which HAHNEMANN had tried before, and they have confirmed his statements in the most striking manner. I conclude this letter with the words of PEREIRA, who is no friend of Homœopathy. He says: "Homœo- pathists are fully justified in considering that the study of the medicinal effects in the healthy body is the only manner to ascertain the real and pathogenic effects of medicines; because, if we prescribe our remedies to the patient, the symptoms of the existing disease become intermixed with those which our remedies have the power of producing, and the latter can, therefore, seldom be clearly and distinctly separated from the former." LETTER X. THE MATERIA MEDICA OF HOMEOPATHISTS. I HAVE purposely given you a full explanation of the rules for experimenting, because the certainty of medical treatment, depends on the knowledge of the medicinal properties, which have been obtained by repeated experiments. During these experiments, we see how the effects develop from a germ, transmit themselves to the different systems, organs, and tissues; and that, con- tinually under different, livelier, and more peculiar symptoms, the further the pathological change ad- vances. The observed phenomena are received as pure observations, independent of pre-conceived opinion or scholastic notions; as facts, without previously inquiring after their importance; and a mode of action which alone corresponds with the true objective investi- gation of nature. These symptoms form, from the beginning to the end, a continuous chain, whose links may be visible, but not understood, if their mutual relation be not recognised. They form the history of medicinal disease, which, like every other disease that 154 has arisen from other causes, must be understood from its commencement and progress, up to its final disap- pearance. This history of disease, therefore, contains: 1. What the experimentee feels: that which is sub- jective. 2. What he himself, the person around, or the physician, observe: that which is objective. Both the subjective and objective must be equally appreciated, and the insight into the development of the medicinal disease is dimmed, if the one or other is solely or chiefly observed. The supposition that HAHNEMANN's Materia Medica, and that of his followers, contains only subjective. symptoms, is utterly false, as a casual look into it, proves; and shows either total ignorance, or an inten- tional disfigurement of truth. Equally incorrect is the excuse, that physiological experiments cannot furnish a standard for the application in disease, because drugs have a different effect upon healthy and upon sick persons. For experience teaches, that every drug, if given only in a sufficient quantity, in doses corresponding to the sus- ceptibility of the organism, shows its constant, positive effects, both in healthy persons, and in those labouring under disease; but that its action differs, as regards the object, inasmuch as it renders the healthy, sick, and makes the sick, well. The effects of drugs, like the symptoms of discase, go from one central point, to the different roads and paths of the organism; and we must follow them up from the point of action and of incorporation, unto their minutest and most distant ramifications. With due attention to this, they are classified in idiopathic and sympathetic, in far and near, in primi- tive and secondary effects, which is of great importance 155 in the recognition of the course of the drug-disease, and the complexity of the symptoms. By drugs, the functions of life are altered, and led into other ways, with which, changes in the tissues, in the concerned organs, and systems, are generally combined. To estimate them properly, and judge them correctly, it is of the highest importance to compare these properties and functions with those which occur in health; and ana- tomy and physiology will materially assist us in this. For this very reason, it is but right to examine the blood, the saliva, the excrements, the results of percussion, of the stethoscope, and the microscope, as well as of pathological anatomy. Nay, in future experiments, attention must be paid also to the more recent improve- ments in ophthalmic pathology, whereby the back, and interior parts of the eye which could not formerly be observed, can now be accurately seen, and their material and functional changes perceived and dis- tinguished through beams of light, which are reflected in the eye, by means of a looking-glass. Undoubtedly the knowledge of the effects of drugs, both of the curative ones, and those which render sick, is materially increased thereby. Through the application of the aforenamed looking-glass, (speculum oculi) we have discovered that many diseases of the eye, hitherto classified among the so-called nervous, or dynamic, ones, and among which, were placed all those which were not clearly understood are now recognised as alterations, degenerations of the nerves and vessels, as vesicular enlargements, extravasations, exudations, loosenings, etc., or, as diseased degenerations of the transparent eye mediæ, so that many of those diseases, which were formerly classified among the dynamic ones, are now 156 placed under the organic, or optical, diseases of the eye. The principal thing, however, remains, the historical development and organic concatenation of the symptoms among each other, and in a so drawn picture, all symptoms, presupposing that they are the results of pure experiment, have their justification as facts, whether anatomy or physiology can explain them or not. The phenomena are, for us, the sole facts, and, by their connexion, we can comprehend the drug-disease, as a whole. From their contemplation, it becomes evident, that every drug produces, in a healthy person, peculiar changes, which only belong to it, and herein lie its peculiarity, its characteristic, or, as HAHNEMANN calls it, its speciality, its singu- larity. These phenomena and peculiarities of remedies must, therefore, be ascertained with the greatest care. A phenomenon is the more peculiarly characteristic the oftener we meet with it in more than one person. For the complete understanding of a drug, it is first of all necessary that a perfect knowledge of all the effects which it produces on different individuals should be obtained, before entering into the details. All phenomena, both in corporal and mental exis- tence, are ascertained in their peculiarities by each disturbed function of an organ; the physical, and, if possible, the chemical change is specified; by a pain, the nature of the changed sensation, the diminution or cessation at certain times, and the commencement or the aggravation at others, as well as their concatenation according to temporary circumstances, are described. The connexion of the phenomena must not be separated. The succession, combination, and alternation of certain 157 symptoms and groups of symptoms, are often very characteristic. The so understood symptoms, in which that which is essential is separated from that which is not, the primary from the secondary, and the pathognomonic from the symptomatic, furnish an objective contemplation of the drug-effects, they are the constituent parts of the picture of the drug-disease, the only guides for the choice of the remedy, because, notwithstanding all subjective condensations, they always represent, in an objective manner, the peculiarity, and the peculiar nature, of the same, they are the real ob- jective foundation, which should never be given up. Out of them, we compose the picture of the drug disease; and from the comparison of the different localities, in which they appear combined in certain forms of disease, we can often determine the general anatomical-histo- logical foundation, with its changes, and, by these means, obtain a deeper insight of the process of disease, and the lawfulness of the effects. Led by facts, we go from the outer, into the inner; and in so far as these elucidate the internal conditions, they are, to us, decisive. We considered, on the contrary, every conclusion, beyond the empirical foundation, as reject- able, because, as I told you before, only presumptive knowledge, and erroneous action, result from it, and science and art are alike injured thereby. Every one who wants to explain the one or other inward process occurring in the nerves, the blood, or the tissues, a process, which is not directly accessible to the senses, is referred from the former field of supposition, and sub- jective conclusions, to that of objective facts. Every explanation is valid in so far only as it can be confirmed by facts. 158 If the symptoms have been classified, so that those which are constantly repeated are noted down as the special, constant, positive ones, to distinguish them from the others, which only appear now and then under particular conditions and modifications-if, moreover, the time and succession have been fixed, in which the drug affects the different systems, organs, tissues, and their functions, both somatically and mentally, and the peculiar characteristics of the physiological effects been given, which HAHNEMANN calls the soul of the drug; then you see that the physiological sphere of action of a drug, according to its nature and peculiarity, represents a more or less numerous succession of stages of dis- ease, the essential seat and course of which become apparent and comprehensible to us if we observe them in an intelligent manner, making a judicious. use of the physiological knowledge which we command. "We say, by making a JUDICIOUS use of the physio- logical knowledge at our command, because the drug- effects, as a peculiar manifestation of general life, have only their rules in and through themselves. Physiology, therefore, can and may only be explanatory. We have then, according to HAHNEMANN, a true Materia Medica, viz., a collection of the real effects of drugs, a code of nature, wherein of every thus ascertained powerful drug a considerable series of particular sensations and symptoms are contained, such as the attentive observer has perceived and noted, and in which the elements of natural diseases encounter their similarities; in one word, artificial diseased conditions, which, for the similar natural conditions of disease, furnish the only true homoeopathic, that is to say, specific curative in- struments for a lasting cure." 159 We then find, further, that many drugs are very like each other in their constant, positive symptoms, and call these kindred drugs, because they most similarly affect the same organs, systems and tissues, and the functions thereof. Hereby (as experience teaches) they are capable of annulling their mutual effects partly or entirely, a fact which transmits the theory of antidotes from the regions of coarse empiricism and speculation to that of experimental, pure, objective investigation of nature. If we closely examine the symptoms which have been obtained by pure experiment, and have been mentally understood, we shall find that every drug possesses-(a) peculiar, positive effects upon the living animal organism, whereby it distinguishes itself from every other, both qualitatively and quantitatively; (b) that it acts especially upon certain systems, organs, or tissues of the living animal; (c) that an essential character is imparted by each drug to the changes of the organs and systems; (d) that all these changes stand in organic arrangement and causal combination among themselves, therefore, form an organism of the drug-disease; (e) that they develope themselves within a fixed lapse of time, continue during a certain period with equal intensity, and disappear in their allotted time. Hereby the physiological fact is confirmed, viz., that quality of stimulation is determining for the nerves, that it impresses their actions with a fixed character, gives them a fixed tinge; so that the re-actions of the organ- ism exactly correspond with the sufferings produced by drugs; and that they therefore mutually determine each other. 160 This property of every drug, viz. to produce in the living animal organism constant, peculiar changes which only appertain to it, has given rise to the expression of specific, whereby, however, is by no means meant the generality (generelle) of the old school medicine, with its dark, chaotic, coarse, empirical contents; but something individual, which has been found by pure objective experiment, and has been men- tally recognised. A specific then is, according to this definition, a drug which in the universality of its effects, is impressed with individual character, and requires for its recognition necessary beforehand, physiological experiment. It is apparent from this, that the specific always cor- responds with the individuality, but never with the species, and that such specific remedies are, in the truest meaning of the word, rational specific ones. It is, therefore, ridiculous if, after so decisive a defi- nition, some persist in adhering to the primitive notion of the kind, and will not permit the historical meta- phorical meaning of the word. To such people no better advice can be given than to go to school again, and there study the language in its primitive meaning as well as in its historical development of metaphors, ere in arrogant ignorance they throw their condemning judg- ment to the world. What have you found until now? A Materia Medica, of which, repeated, pure experiment forms the first principle. HAHNEMANN and his followers started with the conviction, that this doctrine should not as usually submit to the reigning physiological and pathological views, but contain unchangeable objective laws, which were only to be inquired 161 of nature by experiment on the healthy animal organism, whether explained by physiology and pathology or not, On this difficult road, they, by indefatigable zeal, sagacity, self-dependent experiments, and empirical observation, attained a physiological Materia Medica which teaches the ebbing of the phenomena of life, and the manifestation of its laws in the healthy animal organism, when transplaced under unusual conditions, riz., the influence of drugs. This develops itself as a peculiar manifestation of life, independently of every other science, not as an ingenious system of hazarded speculation and hypothesis, or a doctrine of mere proba- bility got up in idle moments, but as the slow work of continued labour; not dry and devoid of marrow from the desk, but replete with vital power from experi- mental life; not constructed from the so-called moral depth of self-consciousness, but brought to light with powerful arms from the rich lodes of objective life. Of such a Materia Medica may be affirmed what the illustrious HALLER said of pathology, that it illumined physiology, nay, with still greater right, that it illu- mined pathology also; so that it doubly reflects the rays which it receives from these two branches for its own explanation. The phenomena are faithfully taken from nature, and, whilst thus the true expression is preserved, the laws and the character are held up to the careful observer, and opportunities everywhere given him for profound thought, but not for mere idle speculation. It remains a rule to grasp the symptomatic picture. of the remedy in its ensemble, and never sepa- rately. as Göthe says, a man's history is his character, then may we maintain that a faithful If, M 162 description of the historical development of remedial effects, is the character of the drug. All speculation. and hypothesis being thus put aside, the pure objec- tive answers to inquiries addressed to unprejudiced nature alone remain, and their doctrine creating a real objective knowledge, forms consequently a true science. And, greater than ARCHIMEDES, who demanded a ful- crum in order to move the world, HAHNEMANN found in experiment in and not outside the world, one that moved medicine in organic harmony. Hereby a Materia Medica is created, which in versatile manner includes the changes caused by medicine in the organism as well in the blood, the nerves, and the tissues, in the processes of formation and dissolution, as in the other functions of life, in the somatical as well as in physical ones, and follows them up carefully from their earliest commence- ment unto the end-a Materia Medica, which observes the chemical processes happening on the limits of life, there- fore also the residues, and thus renders feasible a correct comprehension of the effects of drugs-which teaches the laws of the changes produced by them in the organism, and thus offers to us the means of cure, which we assert with truth that we now know. This great and absolute requirement, the necessary knowledge of the instruments of cure, is therefore guaranteed by HAHNE- MANN and his followers; they have founded and created a true physiological Materia Medica, which now ranks among positive sciences. LETTER XI. THE PATHOLOGY OF HOMEOPATHISTS. THE great BACON of Verulam, says: "Man, as an observer and expositor of Nature, knows only so much of its regulations as he has gleaned from experiment or ob- servation; beyond this, his knowledge and understanding do not extend." "No created mind penetrates into the very arcana of nature," says the renowned HALLER. SYDENHAM, one of the cleverest physicians, expresses himself in the following manner: "It is quite impos- sible that a medical man should know those conditions of disease which have no connection whatever with any of his senses." AUTENRIETH says: "Experience must. become a constantly more perfected theory, if obtained from men whose organisation has not been fixed by the system of a philosopher, but by nature itself. Theory, or mere observation of the laws of thought, can never become Experience-can never show what really is, but only what may be." POUILLET, in his Manual of Physicks, nearly agrees with HALLER, for he says: "We can only form suppositions and hypotheses respecting the internal causes of appearances, symptoms, or of the nature of the power which produces them. These 164 hypotheses are, as it were, questions which are put to Nature, and to which it gives no decided reply by answering Yes or No, but by saying, It may be so, or It may not be so." Here you have the opinions of several authorities, of various times, who agree in point- ing out the very core and limits of objective natural philosophy; viz., that the Laws of Phenomena must be obtained by experiments and unprejudiced observation, but should never be formed à priori from out the depth of over- weening self-confidence and forced upon nature. Chemists and natural philosophers closely adhere to this. Should a physician-who after all is but an investigator of nature-leave this path of reality and enter on that of fantastic hypotheses, and play with the life of the patient as he does with these mere creations of his brain? Never. And so HAHNEMANN has repeatedly said, and has constantly endeavoured to prevent phy- sicians from leaving the road of pure, objective, natural philosophy. Here are his words respecting the comprehension of diseases. "The unprejudiced observer knows the nullity of abstract meditations, which cannot be proved by experience; and however ingenious he may be, he can only observe those changes of the body and mind which may be outwardly recognised; or, in other words, those deviations between the healthy and diseased states of the body as are felt by the patient himself, and ob- served by the physician as well as those around him. All these perceptible signs represent the disease and constitute its true and only form." HAHNEMANN thus applied the recognised rule of natural philosophers to Pathology, and thereby trans- posed it from the realms of caprice and subjective 165 conclusions, into that of objective facts. He is, there- fore, right in saying: "I need no such substitutes (Er- satzmittel) for facts; no mental conclusions, which differ in every physician; you can obtain them yourselves, if you endeavour to ascertain the pure effects of drugs, by only looking at disease for what can be recognised, viz. its symptoms. But in so doing, he always desired that the cause, individuality, prevalent or inherent disease, should be duly considered. It is obvious, that in pathology, as well as in the Materia Medica before alluded to, symptoms must be recognised according to their value, and must be, therefore, duly considered, so that it is not merely allowed, but expected, that one should think over these facts. Let me now tell you how HAHNEMANN, and his successors, practically car- ried out the above maxim; how closely and carefully they examined the patients, in all directions, and en- deavoured to form an organic picture, from the results so obtained. We will begin with the examination of the patient (Krankenexamen). Here the first and indispensable duty of the physi- cian is to take everything in a purely objective manner, without allowing himself to be influenced, by either a physiological, or pathological view. First, the consti- tution and temperament of the patient, his physiog- nomical or bodily and mental peculiarities, if any, his usual occupation, his complexion and the colour of his hair, should be considered. Next, enquire carefully after all previous diseases, particularly after the erup- tive ones, and their treatment, hereditary dispositions, previous and present mode of living; and then pass on to the prescut illness, by inquiring after the supposed cause, and the mode of treatment hitherto pursued. 166 L If possible, the prescriptions, and more particularly the last ones, should be examined. The questions should never be decided ones, to which the patient must answer either by Yes or No. For by so doing he is often in- duced to make false statements, and the pure image of disease is thereby dimmed. All technical expressions should be carefully avoided. The present suffering should be detailed from its very commencement, its gradual progress, not omitting what appears even trivial; and particular attention should be paid to the concatenation (Verkettung) of symptoms, such as the person who relates, has stated them, or as it offers. itself to the first unprejudiced view. Everything is noted down in the very expressions of which the patient made use; those symptoms which appear most im- portant to him, are underlined; next follow those to which he seems to attach less importance; no symptom must be left out because it seems too trivial, as in the treatment, it is often found to be characteristic. As regards the symptoms, all peculiarities, by which they are characterised, should be stated: e.g. aggra- vation or amelioration, at a fixed hour, during the night or day, by cold or heat, repose or movement, in the room or open air, by eating, drinking, coughing, by the weather or change of moon, walking, standing, sitting, lying, the appearance or disappearance of a symptom, or complex (group) of symptoms. In a like manner, each pain, with its peculiar character, should be given; e. g., whether it is dull, beating, throbbing, burning, stinging, drawing, cutting, continued or inter- mitted. What has thus been obtained, is once more carefully looked over, and anything which may have been omitted, is added. It is best to commence with 167 the head; to proceed, next, with the organs of sight, hearing and smelling; then go on to the mouth, teeth, gums, throat and digestive organs, the sexual parts, the chest and extremities, including the action of the pulse; then to the skin and its perspiration, sleep, with its dreams, the state of the mind; and, finally, the secretions, with their changes, both as regards quantity and quality, the changes of the blood, saliva, etc., if any. The results obtained by percussion, the stetho- scope, and microscope, must also be carefully noted down. You see symptoms are here just as objectively and un- prejudicially observed, as in the Materia Medica. Here, as was the case there, a careful observation of all the mani- festations, forms the sole basis of the image of disease in the one instance; and of the picture of the effects of the drug in the other. It is understood, that the obtaining of the one requires the same mental operation as that of the other. This totality of symptoms encompasses their com- plete history; the development, not only of the ones actually present, those recognised by the physician, and felt by the patient, but of those also which existed, which are only tem- porarily there, and change with others that manifest themselves under the most different forms. Here the peculiar characteristic symptoms must be placed at the head, that which is essential must be separated from that which is not, primary symptoms must be distinguished from secondary, pathognomics from sympathetic; therefore, the symptoms must, as it were, be weighed mentally, and physiology, pathology, pathological anatomy, and Materia Medica, as expla- natory sciences, will greatly assist in doing so It remains, however, a law, that in a so regulated (Krank- 168 heitsbild) picture of disease, each symptom finds its proper place, whether it can be explained physiologically or not; and that we, led by it, as it were, try to define the process of disease, of which symptoms are but the outward rays; yet, whilst doing so, we ought not to go further than it can be explained by facts, as we consider with HAHNEMANN, that all conclusions which are not founded upon these, are vain and foolish. Similar to the brave miner, we descend the shaft, deeper and deeper, with the light of facts, from the outside to the interior, and with diffi- culty, it is true, bring to light the real gold of expe- rience; whereas, others, with the nature of hobgoblins, transport themselves, by fantastic conclusions, at once into the interior, and with the unsafe lamp of hypo- thesis, err in the pits, and finally only bring up delusive tinsel. It is, therefore, apparent, that every disease has its peculiar character, and that each should be considered, and treated, separately; that no diseases, locked up in their phenomena, which, like natural bodies (Natur- körper), are characterised in families, sex, and sorts, as they are described like unchangeable appurtenances, in the ordinary general pathological works, but that they are all individual, and special, just like the effects of drugs. All that I wrote to you while delineating the sympto- matic picture, can also be applied to that of disease; and I refer you to it for further details. I grant that it is often difficult, to give the idiopathic and sympathetic manifestations their proper places, as the latter often appear with such violence that they almost dim the former ones. However, a careful examination of the previous diseases of the patient, and repeated exact observation and comparison, generally do away with 169 this difficulty. By this means, one is also better pro- tected against the other fault, viz. that of confounding certain conditions of disease, which, in their mani- festations, show a similarity, but differ in character; e. g. want of blood, and fulness of blood of the brain. He who carefully follows up their origin and develop- ment, will soon recognise the characteristics which escape the superficial mind. It is, however, quite un- founded to infer from this occasionally arising difficulty in diagnosis, that it is incorrect, or impossible, to form the picture of disease from symptoms. Notwithstanding this difficulty, it remains an undeniable truth, that a picture of disease, carefully drawn from nature, in which all symptoms have found their true expression, con- tains, also, the laws and the character of the primitive dis- turbance, and that it, therefore, must everywhere be adhered to, as the real objective foundation; as the cause of dis- turbance becomes apparent to the thinking mind from the gradual development of the symptoms. It is understood that there can be no question of mere complicated symptoms. But just as apparent is it, also, that the disease can only be recognised by its symptoms; and only exists, for us, in these. It is certain, that symp- toms outwardly reflect the most exact picture of the process of disease which occurs in the interior of the organism, and that we, from a proper view of them, are able to recognise its peculiar nature, seat, and cha- racter. It is also understood that, herein, objective and subjective, organic, as well as chemic and physical manifestations," which happen before or after organic processes, find their proper places. A picture of disease, with such minute details, you vainly seek for in medicine. Beginning from the coarse material, 170 objective foundation, and following it up through the dif- ferent systems, organs and tissues; it comprises with equal care, the subjective symptoms, and the softest and lightest vibrations of spiritual and mental life, and thus attains complete and individual characteristics. If he is the cleverest painter, who sketches equally well the out- lines of his figures, and finishes them, in the minutest details, up to artistic animation; so is that physician, also, the most distinguished pathologist and diagnosti- cian, who, with equal conscientiousness, comprises both the objective and the subjective, in one organic picture, and in the same manner in which the last delicate touch of the pencil, or brush, imparts an individual character to the picture; so, in many instances, an apparently insignificant, subjective symptom, imparts a peculiar stamp to the disease, and indicates the treatment. The attention paid by HAHNEMANN, and his disciples, to subjective symptoms, and the value they attached to them and to material objective manifestations, should not, therefore, be blamed, as many, in their narrow intellect, have done; but merits, on the con- trary, the highest respect, and cannot be too highly praised as being beneficial to science and mankind. The painting of so characteristic and minute a picture of disease (krankheitsbild), is no easy task; and many who are unsuccessful at the outset, although considering themselves born geniuses, complain about the confused bulk of symptoms, when they ought rather to complain of the chaotic state of their own minds; for nature justly demands patient and wearisome investigation before she will allow herself to be understood. You must entirely devote yourself to it, if you wish to succeed in penetrat- 171 ing into its evidently hidden secrets, and discovering its laws. Look back! Here also you have, everywhere, the same quiet objective investigation of nature, far from all idle speculation, and vain mania for hypothesis; everywhere the uninterrupted efforts to observe nothing separately, but all in its organic association; nowhere to establish that which is objective, or subjective, or any system, a chief ruler of the entire organism. Here we have a complete objective, organic, perception of life suffering from disease, in nerves, blood, and tissues, with its vital conditions and residues, and all chemical and physical processes, which accompany a contemplation of life under innormal conditions, whereby the laws are derived from disturbed life itself, and not from any extraneous causes; therefore, a real pathology, which has its standard only in, and by itself, and does not take it from other medical, or philosophical, sciences, though these, as explanatory ones, may, nay must, stand by its side. It possesses an organic germ, and therefore, organic life, and is capable of receiving all true observations and experi- ments, and of employing them in further organic development. To it, as to a natural centre, all present and future ascer- tained results converge in ever increasing perfection; and such of them as have not been inaugurated by objective investigation are rejected. It procures thus a real know- ledge of life under abnormal conditions, by teaching us its laws which have been discovered, and not invented, really emanating from facts, and not from hypothesis; it is, therefore, a science in the fullest meaning of the word; a theory resulting from pure objective experience, constantly growing more perfect, and showing us that which really exists, and not that which is merely possible. LETTER XII. THERAPEUTICS OF HOMEOPATHISTS. I HAVE, on a former occasion, told you how HAHNEMANN, after having tried the effects of drugs upon the healthy organism, discovered, by repeated counter-experiments on patients, the law of nature, viz., their bearing on the diseased conditions to be cured, and expressed him- self in the following words:-"Select, to cure the disease. in an agreeable, quick, and sure manner, that remedy which, in its constant, and peculiar effects upon the healthy organism, possesses the greatest possible simi- larity with the chief (pathognomonic) symptoms of the disease." In the same manner in which he formerly, whilst trying to ascertain the effects of drugs, and to comprehend the picture of disease, allowed himself to be governed only by actual experiments and unpre- judiced observations; so was he now enabled, by these two guiding stars, to find this law of nature, to turn to account the physiologically-tried drugs. ! 173 In addition to the two, indestructible supports of Thera- peutics, viz., physiological Materia Medica and pure ob- jective Pathology, a third, founded upon the laws of nature, was discovered, which, as a leading maxim, is generally described by the words, Similia similibus curantur -Like is cured by like. According to this maxim, the great- est similarity between the positive effects of a drug upon the healthy organism and those of the symptoms of the disease to be cured, constitutes the sole, rational, empirical indica- tion for the sure choice of the specific remedy. It is, therefore, clear from what I have told you be- fore, that there is no question here of superficial com- parisons between the symptoms of the drug and those of the disease; but that both must be understood organically, and compared in all their bearings; that, therefore, a picture true to nature must be drawn both of the disease and of the remedy, and that an organic diagnosis must be founded thereon, a proceeding which presumes the profoundest knowledge of Etiology, Se- miotics, and Diagnostics, in a far higher, organic sense than usually. To recapitulate once more, as concisely as possible, the individuality of the patient in its entire compass, according to constitution, age, sex, temperament, former mode of living, pre-existing diseases, hereditary com- plaints, etc.; and, next, the symptoms of the disease from its very commencement unto its actual develop- ment; its duration, its connexion and violence, with its peculiar character and mutual relations, must be care- fully drawn in the picture of disease. Next to all this, the assignable cause, the outward perniciousness, such as cold, dissipation of different kinds, contagion, etc., must be stated. In juxtaposition to a so drawn picture 174 of disease, a remedy like to it in all its peculiarities must be placed; therefore, in choosing such a one, the same points (momente) which guided the enquiry into disease are to be followed. We must, therefore, choose remedies which correspond with the cause of disease, its characteristic symptoms, and the indivi- duality of the patient. This can, however, only take place when, both in the disease and the drug-picture (pathogenesis of the drug), symptoms are weighed and the ordinary phenomenology and symptomatology are raised unto a higher intellectual degree. For only in this manner can it be ascertained that a remedy produces symptoms. which most resemble the existing discased conditions, and from the mental penetration and concatenation of these symptoms only can it be ascertained that it affects the seat of disease in a like manner, and, there- fore, possesses the power of producing, in the interior of the organism, similar diseased conditions, and is, consequently, the remedy which is most fit to effect a cure. It is apparent from this, that only the most careful comparison of the peculiarities, will compass the end. Therefore, after a previous and exact history of the illness, with special consideration of the external per- niciousness, and the exciting cause, symptoms, in their peculiarities, etc., are collected, and progressing from externals to internals; the more hidden ones are only accepted when justified by facts. And symptoms alone guarantee the existence of disease to us, because a disease without symptoms is a nonentity, and exists neither for the patient nor the physician, so from a mentally drawn picture of them, the nature and the laws of the disease become apparent, they deserve thus 175 the highest and fullest attention; and none of them should be sacrificed to arbitrary diagnosis or specula- tion. For in these external signs, the internal picture of disease is reflected; symptoms are, as it were, in- dicators of the diseased conditions of life. For this very reason, the objective picture, which has been obtained by subjective comprehension of the symptoms, is everywhere adhered to as a standard; and a remedy is chosen which in every way corresponds with it. The closer the resemblance between the symptoms of the remedy and the disease, the sooner, more secure, and more pleasant will be the cure. For both the complete symptoms of disease and the corresponding symptomatic picture of the drug, lead to the diseased point in the organism whereby the evil is attacked in its very core, and in the manner indicated by objective facts, and not by vain or idle speculations, a causal or essential cure is effected, without incurring the danger of enter- ing on the slippery path of imaginary creations, by means of hypotheses respecting the cause and existence of disease and cures. It may be said here with justice, that what is conditional is annulled when the condition is complied with. For the unknown changes in the interior of the organism, or the so-called next cause, and the totality of the perceptible changes or symptoms, formed in one organic picture, stand in necessary relation to each other like cause and effect; so that the one cannot exist, or radically disappear, without the other. From this it is apparent, that this treatment deserves the name of causal and rational, in the fullest meaning of the word; because, led by true, objective intellect, it eradicates the disease with the root. 176 This mode of cure passes by the name of Homœopa- thy, and its followers are called Homœopathists. On account of the similarity in the symptoms, between disease and remedy, by which a like (óμotov) is offered to the disease (πalos) in the remedy. It is, therefore, a rational, curative method, founded on experience, which satisfies the demands of science and art; of science, inas- much as, free from all hypotheses, and based only on recognised facts, it carries out real causal cures, and therefore possesses, as truly scientific, the fullest claim to rationality; of art, inasmuch as the cures are obtained in a certain, easy, and quick manner. It is not merely scientific, because its leading maxim, "Similia similibus curantur," is explained ideally, and can be shown to correspond with already existing laws of nature; but because it shows the true objective relation of the remedy to disease, and thus creates a true objective knowledge. Such a maxim, found by repeated experiment, does not. require for its verification any explanation whatever, showing its connexion with other laws of nature, but only and solely that of its actual existence as proved by experiments, just like the chemical and physical laws, and like these, it does not wish to be explained, but known, understood, and recognised. Fools only call such newly-discovered laws incomprehensible, or even absurd, as they may be, perhaps, beyond the reach of their limited understanding, but are never against reason; on the contrary, they are homogeneous and in accordance with it: for facts and their laws are the very source of nourishment to the mind. You see this healing art is not directed against one, or even a few, more conspicuous and troublesome symp- toms; as is the case with that art which I described 177 in the first part of this work; but, as a truly causal and rational one, it possesses for a subject the organic picture, mentally developed from the totality of the symptoms; and only blind folly, or the greatest igno- rance, can call it a symptomatical one, being in its true actual formation, the very opposite to it. Truly, such weak-minded superficial observers, have not the least notion about the preliminary knowledge, of the intel- lectual attributes, of conscientiousness, and indefati- gable care, which such an organic treatment requires; a treatment which gives even to the most trivial symptom its right place, knowing that it is the external manifestation of an internal action. For experience frequently confirms that a symptom, which by many is considered accidental, or only secondary, is often of the highest consequence, and gives, as it were, the most important hint as regards the treat- ment. For this reason, all symptoms, therefore, those also which cannot be explained physiologically, are received (aufgenommen) in the picture of the disease. and remedy; the subjective ones more particularly, because, through them, the more minute differences of the treatment are most characteristically stamped. Listen to ARNOLD:-"In choosing the remedy, it is of consequence to pay attention to each symptom, though it appear uncertain, or insignificant, or incom- prehensible to the physiologist, as, from it, often the proper choice of the remedy depends. Thus, nux vomica has the peculiarity, that many symptoms, which are produced by it, occur on waking in the morning, or increase in intensity about that time; that many of them develop themselves chiefly after dinner, some whilst moving in the open air; and that several are in- N 178 creased by mental exertion. These valuable character- istics for the choice of the remedy cannot at present be physiologically explained; the aggravation, on touching, however, is thereby interpreted, that this drug, in con- sequence of its especial action upon the spinal marrow, increases the susceptibility of the nervous system to ex- ternal impressions which affect the skin; this constitutes. one of the essential effects of this remedy. The prac- titioner, who is often safely guided in the choice of the remedy by symptoms which have not been explained physiologically, should, therefore, not reject the phy- siological analysis of disease and of the remedial effects (but he must adhere, whilst doing so, to the objective, real symptomatic picture); on the other side, it is very disadvantageous if physiological physicians are so proud of their science, that they reject pure empirical in- dications." And, further on, ARNOLD continues: "The physician who, in order to cure, would only avail himself of that experience which has been physiologically cleared up and explained, would lose many valuable facts. I will quote you a few examples out of my practice. "The first was a prosopalgia, which, after careful investigation, corresponded organically with the sympto- matic picture of rhus. Relief, but no cure, followed its administration. I examined again, and then ascertained that the pain was dreadfully aggravated by lying down, and relieved by rising up. This led me to ferrum, which possesses this characteristic symptom; and, as in other respects its effects corresponded to the case before me, I gave it, and the pain was permanently removed. "In a similar manner, I gave rhus in a case of coxalgia of nine months' duration, which had resisted all sorts of 179 allopathic remedies and baths; but its administration proved equally unsuccessful. I re-examined the patient, and was informed that the pain grew insupportable by standing, with the feeling as if the thigh would break through. This circumstance led me to valeriana, which has among its symptoms just such a coxalgia. A couple of doses of the 30th dilution effected a complete cure in three days." Physiology cannot actually maintain this peculiarity of iron and of valeriana, and, notwithstanding this, the cure depended on them in both cases. Similar narratives of cure are related by RAU, who thus continues:-" Our pathologists, it is true, do ex- plain everything. It is not at all difficult for us to show that a toothache, combined with severe sneezing, is of a catarrhal nature, but it may also belong to that kind in which sneezing is not present; and still this sneezing was, in the above-stated case, with reference to the totality of symptoms, so essential a symptom, that its consideration led to rapid recovery." (He had given cyclamen with great success, to a lady who suf- fered from severe toothache combined with sneezing, because this remedy possesses such a kind of toothache among its symptoms.) It is clear that none of the other symptoms in the organic picture of disease and in that of the remedy should be neglected. It is a fact, which cannot be overturned, namely, that if you succeed in finding the remedy which corresponds in every point with the disease, the cure often follows with the rapidity of lightning. Every busy homoeopathic physician knows that such cures are not imaginary, but real occurrences. But this success depends upon the existing state of 180 our objective and subjective physiological, pathological, and pharmacodynamical knowledge; and, also, from the capability of the patient to observe himself and describe his state in an exact and decided manner. For this very reason it sometimes occurs, that a remedy which is given with all possible precaution and care against a disease, in the investigation of which one has been equally cautious and careful, proves unsuc- cessful, as I showed you in the cases alluded to before; whereas further examination proved it was not. the appropriate homoeopathic remedy, because the one which then corresponded with the more perfected picture of disease cured immediately. Although these difficulties happen now and then, they do not justify us in drawing conclusions respecting the insufficiency of the maxim, for it confirms itself in the most striking manner, in every instance where the symp- toms of the disease correspond with the effects of the drug. But for this, he everywhere exacts individual descrip-. tions. He is not satisfied with generalities, in ac- cordance with which, it is said, that a remedy affects the mucous membranes; but it must be stated under what peculiar symptoms e.g. zincum, pulsatilla, mercury, ammonia, affect the mucous membrane. We, therefore, must know the history of all the effects of the remedy upon the organism, and comprehend the picture of disease individually, and exactly in its minutest details. Listen, also, to what ARNOLD says on this subject: "We should not be satisfied with the generally used denominations; but enter closer into the details of the diseased condition. It is of little service to know that an organ is in that condition which is called inflamma- 181 tion. We must endeavour to ascertain the origin of this condition, the particular changes in the organ itself, the accompanying symptoms (subjective and ob- jective), and the general conditions of the systems, as well as the quality of the liquids. How different are the states which are grouped together under the name of inflammation of the lungs, but which must be closer separated, so as to find their corresponding remedy, according to circumstances, either in aconite, bryonia, nitrum, tartarus emeticus, phosphor, rhus, belladonna, hyoscyamus, china, etc." And again: "It is not sufficient for us to know that aconite, phosphor, and several other remedies produce symptoms in the living organism which resemble those which, in many in- stances, are observed in inflammation of the lungs, and that they often proved their curative power in such instances; we must also gather the conviction that they are able to produce hyperæmia (hyperämie) and stagnation of the blood in the lungs; we must endea- vour, also, to discover what changes they may, besides. this, occasion in the solid and liquid parts of the organism." It is clear, that all other subjective and objective. symptoms are taken into consideration, and that the picture of disease must be drawn in a similar manner. To show you how the changes in the liquid and solid parts are put down and valued in the picture of disease and in that of the drug, I will here communicate to you two interesting cures of petechial fever (Blutflecken krankheit) which Dr. ARNOLD, equally distinguished as a physiologist and a practical physician, relates in the Homeopathic Quarterly Journal, edited by Drs. MÜLLER and MEYER, vol. v., p. 168. Here are his own words :--- 182 "The son of Mr. G-, cooper; was taken ill in Au- gust, 1852, with the petechial fever having felt indis- posed a few days before. Eight days before his illness I saw him, and found him to be a lively, strong boy of ten years of age, having a fresh complexion, and without the slightest trace of any scrofulous taint, or of any other predisposition towards disease; but whose looks proved, on the contrary, that he was accustomed to be out of doors the greater part of the day. No reason could be adduced as to how his sickness arose, except- ing the incident that the lad had been frequently bathing, with his friends, in the river Neckar during the last hot days. If, on the one side, one felt disposed to attribute the disease to this immoderate bathing, it was a striking fact, on the other, that none of his comrades, among whom were several delicate boys, had been attacked by the same complaint. “When first I saw the boy he was in bed; complained of exhaustion, and was literally covered with red spots and stripes. On the more tender and softer parts, which are generally covered up, the number of petechia (spots) was great; but none could be perceived either on the hands or on the face. The boy's nose bled frequently; now without any cause, now on moving quickly; the gums bled slightly, but on them, and in the cavity of the mouth, no petechia could be dis- covered. Beyond the feeling of debility, no symptom of general suffering could be ascertained. "On the 21st of August, 1852, I gave the following prescription:- "Rec. solut. Phosphori dilut. 2 (decimal scale) gtt. viii. Aq. destillatæ unc. iv. (( MS.-Every two hours 1 tablespoonful. 183 I also ordered his chamber to be repeatedly aired, and advised nourishing, easy-digestible food. "On the 23rd of August, his general condition had essentially improved. During the last twelve hours no bleeding had occurred; the spots had grown paler, and seemed to have diminished in number. At the same time the boy, who had left his bed, gave me the assurance that he felt less weak; and his parents in- formed me, also, that his appetite had improved, and that their child had grown more cheerful. The medi- cine being exhausted, I ordered it to be prepared anew, and prescribed a tablespoonful to be taken every three hours. "On the 26th of August, I saw the boy playing in the garden; the bleeding from the nose had ceased; some of the spots had entirely disappeared, and those which yet remained had grown considerably paler. I now prescribed no further medicine, and found him, eight days later, completely recovered. "On the 4th of February, of the present year (1854), I was called in to see the daughter of Mrs. Ch. N———. The girl, eight years of age, is well nourished, and en- joyed good health up to the present moment. Her constitution may be described as lymphatic; and from this we may infer a disposition towards a scrofulous habit. No cause for the present illness could be ascer- tained, unless one could attribute it to the death of her father, who had suffered for years from enlargement of the heart, and who died suddenly a few days ago. It would be no easy task to state in how far this affected the girl, as she had led a very quiet life, and had not been accustomed to describe her feelings. 184 "The mother had observed no change in the child until it was attacked, on the 4th of February, with bleeding from the nose and mouth. On examining her daughter more closely, she perceived a number of spots and stripes over the entire body, which induced her to send at once for medical assistance, although the little one did not complain of anything else. "I not only found petechiæ, in vast numbers, on the entire surface of the body, so that in some of the softer parts of the skin they were very close together, but I also met with hemorrhagical spots and stripes on the tongue and on the other parts of the cavity of the mouth. Bleeding from the nose and mouth occurred without any apparent cause, and a great deal of blood was thrown up by hawking and coughing, mostly on waking after a short sleep. The stools also contained some blood, being surrounded with a thin layer of it. The blood itself offered nothing abnormal; and my time would not allow of any microscopical examination. "It was remarkable, that these striking symptoms of discharge of blood did not disturb any organ, and were unaccompanied either by fever or pain; the child felt very exhausted, as a natural consequence of the loss of blood, and, for this very reason, remained willingly in bed. I prescribed- "Rec. solut. Phosphori dilut. 2, gtt. vi. (C 'Aq. destillatæ unc. iij. "MS.-Every two hours half a tablespoonful. "I again visited my little patient on the 6th of Feb- ruary, and was told that the bleeding from nose and mouth did not return after the third dose of the me- dicine; and that, on the next time of waking, no 185 further blood was hawked up. On examining her care- fully, I saw that the intensity of the spots had very much diminished, both on the surface of the body as well as in the cavity of the mouth. The same remedy was again given, but at intervals of three hours only; and I had the satisfaction of dismissing the patient as cured on the 9th of February. "Of bleeding no trace could be discovered during the last days; some of the spots had disappeared altogether, and others had left behind them a slight reddish, or yellow-reddish, color of the skin. This also soon went off, without the administration of any further medicine, so that when I visited the child, a fortnight afterwards, no trace of them or the disease could be discovered. "Although these facts are in themselves sufficient proof of the efficacy of phosphor in petechial fever, it is allowable to detail here the reasons which induced me to prescribe this remedy, and to compare this treatment with the one generally in vogue. "In the petechial fever it served to physicians, as an indication for healing, to impart more firmness to the solids and liquids, and to check the bleeding immedi- ately (J. G. VOGEL's Manual of Practical Pharmacology, vol. v., § 7, p. 212). In accordance with this indication, he used acids, and, in particular, sulphuric acid, china, and other plants containing tannin, alumina, etc. "Although this indication is no longer the same, perhaps on account of its not agreeing with the more recent pathological views, yet physicians kept using the same remedies, as they perhaps felt that their doctrine had nothing better to offer them. This supe- riority is now offered to us by the law of similarity, 186 and which, it is true, allows us to recognise in sulphuric acid and china some curative relation to petechial fever, although it is but trifling when compared to that offered us by phosphor. The experience at the bedside of the patient again confirms, in the most complete manner possible, the law of Similia similibus curantur. "He who, from visiting hospitals and from self-expe- rience, has ascertained the result of the so long-praised remedies, has also obtained the conviction that sulphuric acid has the power of mitigating the bleeding in pete- chial fever; that, by this remedy, it may be kept within bounds, but that a rapid recovery must not be expected. On the contrary, that by its imprudent use other dis- turbances are produced in the body. Of china, he will know that those who suffer from this disease can, some- times, not endure it; and, again, that in moderate doses it proves useful when the patient has become. very debilitated through loss of blood. The cases treated according to the above method, offer no clinical results on which we can depend, as both remedies are generally administered simultaneously. "The observations respecting the curative action of phosphor offer a more certain result, as this remedy was given by itself, and no change had to be made in the patient's mode of life; and because amelioration and cure followed so soon after each other that the the curative effect of the medicine became apparent. ،، Phosphor causes, in healthy persons, most of the symptoms referred to in the above cases. The gums blced easily; blood often comes into the mouth; throwing up of blood on coughing; bleeding from the nose, now in single drops, now very severe; passing blood through the anus, in various forms; many small, red spots, like 187 petechiæ; also, red stripes, in particular on the arms and legs. "Add to these some further symptoms which I observ- ed in animals, such as 1. Diminution in the circum- ference and consistency of the blood-globules, which become smaller and more elastic, and can, therefore, take different forms. Connect with this, that the blood. is more liquid and of a darker colour. 2. Red spots, and more extended parts in the mucous membranes and different organs, which, far from being of an inflamma- tory nature, are more the consequence of a dissolution of the blood, produced by phosphor. 3. Extravasation of blood in the cavities and tissues of organs; therefore internal bleeding, which, alike with the red spots, is based on the re-solution of the blood. "If such similarities exist between the symptoms of disease and those of a drug, then the call to make a therapeutical use of them, according to the Homœo- pathic law of cure, is very urgent. "If the result of the cure shows itself so forcibly, as in the cases I have observed, it carries with it the proofs that the law of similarity goes beyond the ex- ternal symptoms; that it rests upon profounder relations between the action of a drug and disease; and that, in the true sense of the word, it affects the nature of both, as I have already previously tried to prove." Thus far ARNOLD. Homœopathists consider, also, any hints respecting the primary cause, temperament, effect produced by the weather, very important; although these have little or no value in the eyes of other physicians. HAHNEMANN has given us many such intimations; thus, he mentions to us the individualities of nux vomica and 188 pulsatilla. For the first remedy, the choleric and choleric-sanguine temperament, with its sudden out- bursts of passion and hasty deeds, spiteful, malicious, angry character; its fitness for females, if the menses appear a few days too soon and too copious. As regards the etiological indications, its fitness for persons suffer- ing from the evil effects of coffee, wine, or who lead a sedentary life. Pulsatilla, on the contrary, possesses the timid and phlegmatic temperament, with its inclina- tion, to yield and shed tears; is useful to the female sex if the menses appear a few days over the right time; etc. Like nux vomica, other remedies are adduced by HAHNEMANN as the causes of disease. Arnica, against a fall, blow, etc.; rhus, against sprains, etc.; opium, against the evil effects of fear; aconite, ignatia, and staphy- sagria, against the effects of other mental affections. HIRSCHELL says, very truly: "These physical differ- ences belonging to drugs, which have been carefully ascertained by physiological experiment, give us one of the most important indications even in those diseases where they appear only secondary considerations, and offer us not seldom there, where allopathy forsakes us, a precious treasure of confirmed observations. (C We, for instance, remind you of the effects of anxiety, fright, and fear; and refer, in these cases, to aconite, opium, pulsatilla, ignatia, phosphoric acid, and staphysagria; of grief and sorrow, to capsicum, and of the evil effects of home-sickness, to colocynth, and ignatia; and of the evil effects of insult, outrages, etc., to chamomilla, and colocynth, which are the chief remedies for the evil effects from anger. Dispositions, such as irritability, susceptibility, rage, mildness, whin- aurum; 189 ing, suspicion, shyness, obstinacy, indifference, and melancholy; mental directions, such as imagination, imaginary deception, and amorousness; expressions of the will, such as malice, blood-thirstiness, vengeance, presumption, self-destructiveness, and greediness; all find their reflected images in the Homœopathic Materia Medica." As in Homœopathy, however, all the symptoms of disease and of the drug must be individually developed in every direction as much as possible, it is apparent that it is not the mere symptom which indicates the appropriateness of arnica, rhus, etc., but the total con- dition which was produced by the perniciousness; and that arnica, rhus, etc., were given because they produce effects in the healthy organism which resemble that estate which was produced by the injury. The homeopathic treatment, therefore, also manifests itself as a causal, rational one; and the mental opera- tion thereby absolutely required forms a striking contrast to the malicious substitution of mechanical covering of symptoms. The following words of HIRSCHELL testify this also: "We must, finally, mention another similarity, which, even more than the others, would indicate the great precaution which Homœopathy uses in the application of the specific remedy, viz. the consideration of the tellurical, miasmatic, and epidemical influences. In the same manner as, not alone the anatomical and physiological, but also the physical and chemical con- ditions of the disease, as far as they rest with it, must be objects of investigation; so also are the modifications which disease undergoes by outward, physical, chemical events and conditions, required for the perfect recogni- 190 tion of its peculiar nature. And we are fortunate enough to possess drugs which correspond with these deviations caused by temperature, climate, and changes of the weather; because, whilst experimenting with them, the sufferings increase or diminish in intensity, if exposed to higher or lower degrees of temperature; during the different times of the day and seasons of the year; during the changes of the weather, such as full moon, new moon, etc.; by the influence of air and wind in general, or the different sorts of the same, such as sultry air, etc. "And who would deny that these momentums have a great influence upon the human organism; that, con- sequently, under these conditions, the manifestations in the remedies deserve consideration in particular where the consequences of these influences are involved." I I cannot avoid reminding you here of PASTEUR. His manner, to discover the alterations which chemical preparations, acids, salts, etc., do undergo by light, and to determine this change, is found ingenious and deserv- ing of being imitated: I now ask, Is it less ingenious, less worthy of being imitated, if homeopathists care- fully observe the most sensitive of all re-agents? mean, the human body in its diseased conditions, whe- ther these are caused by drugs or other influences. If they note down how it is affected by temperature, climate, change of moon, time of day, light, etc.; establish the differences, and, without neglecting the coarser material outline, complete the symptomatic picture both of disease and drug, with due outward and inward estimation of every manifestation at its proper place, unto the nicest, but generally very characteristic features, and from this determine their action? Is such 191 conduct not the duty of every true, natural, philo- sophical physician? The comprehension and treatment of epidemical disease, give us a striking example of the great pre- caution of the homœopathists. Here as many cases as possible are characteristically drawn, put together, and compared with each other. From this results a greater picture of disease, including all the separate ones, forming, as it were, a great organism of disease, of which the separate ones form the systems and organs. This organism, the image of the most varying pro- cesses of disease, is now compared in every direction with the ascertained effects of the drugs experimented with, which also contain organic images of the most varying processes of disease, and that remedy is chosen which produces an organism closely resembling that which the epidemic produces in healthy man. By this means, not alone the clearer marked pictures of disease of the epidemic are cured, but also the separate mem- bers, those disturbances manifesting themselves merely through one symptom, which only through the above organic regulation appear in their true nature. In practice, this is of the greatest importance, because the character of epidemics frequently varies though the epidemics seem alike. This, also, is the reason why remedies, which were successfully administered in some epidemics, proved ineffective in others. Science enables Homœopathists, therefore, to afford assistance to humanity even in the most difficult and dangerous cases, as has been proved, in a most brilliant manner, in the different cholera epidemics. The fol- lowing will show how useful the true comprehension of the epidemical picture proves in practice. 192 I treated a drunkard for delirium tremens. On his recovery from the disease, he got a violent coxalgia, the attacks of which came on every morning about four o'clock. At that time, cholerine was raging, and its attacks occurred about the same time; and for it veratrum proved to be the specific remedy. This struck me forcibly, so finding that the symptoms recorded of veratrum possessed a similar coxalgia, I considered that the coxalgia under treatment was owing to the causa nocens of the epidemic, which produced vomiting and purging in one, and confusion of the head with general prostration of strength in the other, and had, in this patient, attacked the weakest part, e.g. the sciatic nerve, causing a coxalgia possessing the peculiar characteristics of the epidemic. I have to observe, that he had pre- viously suffered from coxalgia, so that the disposition to it was present. All these considerations induced me to select veratrum instead of nux vomica, though the latter remedy produces a similar coxalgia, and it was also indicated by the patient's mode of living. I gave one drop, of the ninth dilution, of veratrum, after which no further attack occurred. In stating the above case, I have been as concise as possible; because it is not my intention to write Thera- peutics, but merely to give their leading points. They have all been obtained by the proper investigation of nature. The maxim of Similia similibus curantur, unites Pathology and Materia Medica, these two powerful supports of medical science, into real scientific Therapeutics, because they are in accordance with nature. Everywhere we meet with the pure language of nature, which has been enquired into without prejudice; everywhere the re-actions, phenomena, and answers of complete organic 193 ! life are grasped, and the laws regulating them are sought after with an enquiring and comparing mind. It is, therefore, absolutely necessary to comprehend the symp- toms of disease, as well as those produced by drugs, to know the character of both; in short, to understand that which constitutes the very spirit in medicine. Here, we do not stop at a superficial symptomatology of disease and remedy, but penetrate into the very cha- racteristics of both, and avail ourselves of everything which may throw light on the individual case, and assist us in the choice of the remedy. The choice of the remedy is, therefore, the production of the criticising mind, a comprehension of all that is perceptible, and not a mere ostentatious seeking after the nature of disease. Here, the thread has been found in a rational, empirical manner, which, in each separate case, leads to the choice of the specific remedy. Here, no scattering, or over-valuation of the one or other system, or auxiliary means of inquiry, occur; but the ensemble and organic connexion are never lost sight of. Here, no sacrifice is made to the deifying self-love of rationalism, neither are facts and phenomena embellished, partially explained, nor entirely denied, to satisfy the rage for ex- planation. But that which has been observed is adhered to with rigid conscientiousness, and moulded into organic form, in order that by the more distinct comprehension of the mutual relations thus established between disease and remedy, Therapeutics can become practically useful. ; Here, it is not sufficient to state, whilst speaking of the symptoms of disease and drug, that some nerve, organ, or system, are affected; and, to give in this manner only, the coarser outlines of the picture, the mere skeleton of the disease and drug, but the finer and frequently most 0 194 characteristic features for the development of the organic individuality are absolutely exacted. Here, the specific method of the Old and New School, surrounded by illu- sion and hypothesis, is, as it were, unlocked through the maxim of Similia similibus curantur, and brought to the daylight of real science. In this maxim, the various rays of the specific which history has dispersed, con- centrate as in their natural focus, and become useful, indestructible material for the formation of a true, scientific, and practical medical science, in which organic unity forms the sole rule of conduct for practice, and in which our knowledge acquires clearness, our deeds con- sistency, and benevolence. In this organic unity, Materia Medica and Pathology have grown up together, and become organically cemented by the objective law of associations. But in this union they are as different manifestations of single uniform life, self-dependent, have their standard only in them- selves, and appear, therefore, never in a determinate, but only in an explanatory manner, the one for the other. They subordinate themselves to individual life, from which they receive their laws, which, in every instance, have been ascertained through Natural Philosophy, and have not been invented by speculation and hypotheses. Individual laws, sustained by organic unity, and stamped by it in a peculiar manner, form here true medical science, and they are to the whole what the organs and systems are to the organism, representing it scientifically in its numerous manifestations. Here, science develops itself out of one organic vital germ; comprises all its orga- nisations in organic connexion, and, whilst it acquaints us with the real laws of the manifestations of life, it teaches us, at the same time, the means to maintain healthy 195 life, and leads back to its normal state that which is afflicted with disease. Thus it becomes a true curative method, and enables the physician to solve efficiently the noble problem of cure. And this science is not a vague one, blown to and fro by the winds of suppositions and opinions! It is through its organic unity, in spite of all its manifoldness, as firm and unchangeable as nature itself, of which it received its laws, as immoveable pillars, and, in ever increasing completion, is still capable of development. In it, all physicians agree, because the reign of hypotheses has here been replaced by that of facts, and all animated by organic blood, work actively to complete science and the curative art for their own benefit, as well as that of humanity in general. Such a science is worthy of the labour of the noble- minded, and happy will be the time when it shall be generally recognised, adopted, and practised. And this time will come; it is not far off, for truth penetrates all obstacles; and, filled with enthusiasm and gratitude, Humanity offers to it the nobly gained laurels. LETTER XIII. HISTORICAL EVIDENCE IN FAVOUR OF THE PRINCIPLE OF SIMILARITY. ALL the laws recognised in physical sciences have an empirical foundation. The frequent and careful ob- servance of phenomena can alone enable us to compre- hend them. Intellect attempts in vain to construct, a priori, some valid rule, and its endeavours to arrive at the primeval cause, the original source of life, prove equally fruitless. We find no fault with him who tries to form, for his own guidance, some idea of the inward connexion of the manifestations and processes which happen in the most secret laboratories of life; but he should give them merely as his subjective views, and avoid carefully attaching any objective value, or to substitute them for real truths, although I am sorry to say that it has frequently been the case in medicine. Homœopathists who have endeavoured to explain the processes of cure through the maxim of SIMILIA SIMILIBUS CURANTUR have not fallen into the same error. Notwithstanding all the ingenuity which cannot be denied to the various explanatory attempts. of HAHNEMANN, RAU, RUMMEL, MOSTHOFF, GERSTEL, KOCH, GRIESZELICH, TRINKS, etc., these gentlemen have avoided believing that they had lifted the impene- 197 trable veil of innermost life. They never thought of substituting their view of the process of cure for facts, and to make them the standard of their proceedings. They were always guided by the maxim of "similia similibus," and considered it equally foolish to substitute explanation for experiment, and to introduce the cure accordingly, just as the chemist considers it foolish to fix the formation of a salt after the mere hypothesis of the mutual action of bases and acids instead of according to the atomical proportions ascertained by pure, unfalsified experiment. But it is far better to progress steadily on the road of facts, and to endeavour to discover the laws on which these rest, than to indulge in speculative theories; for :- Ein Kerl, der speculirt Ist wie ein Thier, auf dürrer Heide Von einem bösen Geist im Kreis herumgeführt, Und rings umher liegt schöne grüne Weide." Life's operations can alone be disclosed by repeated experiments and observations, and it is only through these that science and art can be advanced. If we, therefore, comprehend life in so complete and organic a manner, and render it in that life-like description which Homœopathy exacts, then we shall have con- A speculating wretch Is like a brute, on bare, uncultur'd ground, Driv'n by an evil spirit round and round, While all beyond rich pastures smiling stretch.” Faust. MISS SEDGEWICK. 198 templated its laws and inward cause in as far as it is possible. Listen to Goethe:- "Whilst observing nature, study it deeply, for nothing is simply internal or external, for what exists inwardly exists also outwardly; in this manner penetrate, with- out delay, nature's secrets." Convinced of the truth of this declaration, I will not increase, even by one, the many suppositions. If the explanation is to be a true, an exhaustible one, it co- incides immediately with that of the innermost process of life. But you have been told, in physiology and pathology, that this is still shrouded in the profoundest mystery. It seems wiser to me to bestow time on the in- vestigation and discovery of facts, instead of wasting it on subjective hypothetical conclusions, so as to obtain more and more building materials for a true scientific explanation. For a successful treatment of the physical sciences, therefore of medicine also-it is not alone advisable, but a necessary law, to ascertain the boundaries of ob- jective knowledge, and to act accordingly, and not to jump at conclusions. Through the first mode of proceeding, true objective natural philosophy is gained; through the second, a pseudo-physical science replete with hypotheses and de- lusions. In the meanwhile, I consider it both important and interesting to adduce some support from history, which, unfettered by theories and scholastic dogmas, will furnish you with the proof that, already, in the earliest days, diseases were cured according to the principle of "similia similibus," and it matters little whether the mere obscure 199 presentiment or the real conviction of the existence of such a law, have led to it. Thus we find, in HIPPOCRATES, that of two simultaneous pains, the stronger always con- quers the weaker (APHORISM xlvi. p. 1246), that cold water causes convulsions, lockjaw, chills, and numbness (APHORISM xvii. p. 1253), and that pouring cold water over the body in cases of tetanus restores its natural heat (APHORISM xxi. ibid.). Cold substances, such as snow and ice, produce hæmorrhages (APHORISM XXIV. p. 1254), but the appli- cation of cold water cures such cases also (APHORISM xxiii. p. 1253). Cold water produces also pain (in sore places), induration of the skin, and convulsions, etc. (APHORISM XX. ibid.), but it also eases or removes the pain and the swelling of joints, podagraical attacks, and cramps (APHORISM XXV. p. 1254). In the writings of the followers of HIPPOCRATES, viz., THESALLOS, POLY- BOS, PHILISTION, and others, it is said that garlic pro- duces heaviness of the head, besides restlessness; and, notwithstanding this, it is recommended in cases of in- toxication. (De victus ratione in morbis acutis, fol. iv. p. 404.) Wine removes the heat resulting after dinner, for it warms and thus promotes digestion. (De affectionibus liber, fol. v. p. 530). Wine, mixed with honeywater is advised against ailments of the liver, (De internis affectionibus liber, fol. v. p. 547), notwith- standing the observation that it swells up both liver and spleen, produces thirst, inflation of the stomach and the upper intestines, stems flatulence in the hypochon- driacal regions, and is hurtful to bilious persons, (De vict. ratione in morb. acut., p. 392), and that inflam. mation of the liver happens easily after drinking a strong sort of wine in summer. (De int. affictionibus, 200 p. 548.) In the Book on Epilepsy it is said, "Diseases are mostly cured by that which produces them, (De morbo sacro, fol. iii. p. 310), a sentence which, in the Περι τοπων ” is discussed more fully in the following manner :— Book " Περι τοπων "Through the law of similia similibus diseases are pro- duced and cured. That which causes strangury, cough, diarrhœa, and vomiting has also the power of curing these evils (De locis in homine, fol. iv. p. 421). Of the fruits of the turpentine tree, it was understood that they produce an opposite alterative effect upon the vascular system of the uterus, that they produce and suppress secretions. of blood from the same; for which reason they check severe hæmorrhage from this structure, and promote. menstruation also. (De nat. mulier. 583). To melan- choly persons, inclined to commit suicide, the mandrake root was strongly recommended, but they were at the same time advised not to take it in doses sufficiently strong to cause madness. (De locis in homine, 420.) "If you had DEMOCRITUS writes to HIPPOCRATES: given veratrum to me, as you do to a madman, intel- lect would have diverged into madness, and your science. would have been blamed, for having, as it were, been the cause of the madness; for veratrum given to the intellectual causes them to become mad, but is, in spite of this, of very great service in cases of madness. ASCLEPIADES, the Bithynian, who founded the metho- dical school, gives wine to check profuse perspiration, and teaches, at the same time, that wine produces fre- quent perspirations on the outer surface of the skin. In cerebral inflammation, he advises that only small doses of wine should be administered, because it incited. phrenitical persons casily to madness. STÖRCK says: “If 201 stramonium unsettles the mind and produces insanity in those who are healthy, is it not then allowable to try, whether by changing the ideas in mad people, it cannot bring back reason (Libell de Stram, p. 8.)?" PARACELSUS says: "It is a wrong rule set up by GALE- NUS of prescribing remedies, which have an opposite effect to that of the disease. It is erroneous; for those should be given which, in their effects, resemble the disease." BASILIUS VALENTINUS, says in his work De Micro- cosmo: “Like is to be removed by like, and not by oppo- sites, heat by heat, and cold by cold." DE HAEN also knew this maxim, and mentions, that "dulcamara in large doses produces convulsions and delirium, and in small doses cures like complaints." STAHL says, "The rule to cure opposites by opposites (contraria contrariis), adopted in Pharmacology, is wrong, and that it was his conviction that diseases are cured by similia similibus; e.g., burns, by approaching them to the fire; frozen members, by applying snow and the coldest water possible to them. Inflammation and bruises, by spirituous extracts. In the same manner he cures the disposition to exyregmy (acidity of the stomach), by very small doses of vitriolic acid, in cases where numerous absorbing powders had been used in vain" (Jo. Hummelii commentatio de Arthride tam tortorea quam scorbutica, seu podagra et scorbuto. Budingæ, 1738, fol. 40-42). BOULDUC agrees that, to the purging property of Rheum, its curative power in diarrhoea is to be attri- buted (Mem. de l'Acad. Royale, 1716). DETHARDING says, that senna leaves cure colic, be- cause they have the power of producing this disease in 202 healthy persons. BARTHALON says, that electricity alleviates and cures the pain which it has the power of producing (Medec. Electric. 11. p. 15, 282). THOURY asserts, that positive electricity does increase the pulse, and lessens the same when disease has increased it (Mem. lu à l'Acad. de Caen). According to LAZARE, electricity causes varicose swellings, ischias, convulsions, and cures them again. BURDACH (Pharmacology, p. 288 s. 99) says: "If in an organ abnormal conditions exist, the remedy which can produce like abnormities in the same organ will also cure them. In burns, a stronger degree of heat should be applied; when limbs are frozen, snow and the coldest water should be applied." Helleborus can produce blindness by over-excitement, but can also, because it specifically affects the retina, cause a healthy reaction in case of amaurosis. He con- tinues saying,- "Belladonna can produce madness, cramp in the pha- rynx in healthy persons; and when these organs are affected through the bite of a mad dog, it will, if used in proper doses, lead back the vital energy of these organs to its normal state, in the same manner as the proximity of the candle flame takes away the inflamma- tion caused by the melted sealing-wax falling on the fingers" (ibid. p.130). You here find the maxim of Similia Similibus very frequently expressed, with more or less clearness; but it was devoid of that importance which it has since ac- quired. The key of experiment was wanting to penetrate victoriously into practical medical science. Here the quotation of some further cases of medical men of the old school, who wrote before Homœopathy was thought of, will not be out of place. 203 You will find, that, whilst some of them assume that a certain remedy cured a certain disease; others affirm, that the same remedy produced similar diseases. The English sweating fever, which, according to Willis's testimony, killed ninety-nine out of every hundred, was only treated successfully when sudorifics. were prescribed (Sennert). Hippocrates cured a cholera, which resisted all other remedies, by helleborus albus, which, accord- ing to FOREST and RAIMAN, produces all the symp- toms of cholera. WIETHERING gave hyoscyamus in dysphagia, and also in some kinds of madness. with brilliant success. In the same manner, cramps resembling epilepsy, were cured through hyoscyamus, by MAYERNE, STÖRCK, COLLINS, which, according to the observations of E. CAMERARIUS, C. SELIGER, HÜNERWOLF, A. HAMILTON, PLANCHON, ACOSTA and others, causes similar convulsions to those of epilepsy, complaints of deglutition, and madness. SCHENKBECKER cured by this plant a chronic giddiness, and HUNerwolf, BLUM, NAVIER, PLANCHON, STEDMANN, GREDING, Ber- NIGAU, and others, assert, that in a high degree, it has the power of producing a similar state. According to HUXHAM, camphor proved beneficial in a certain kind of slow typhus, in which the temperature of the body was lowered, sensitiveness decreased, and vital energy considerably depressed. According to G. ALEXANDER, CULLEN, and F. HOFFMANN, it produces exactly the same conditions. According to EVERS, SCHMUCKER, SCHMALZ, MÜNCH, and others, belladonna has proved its efficacy in various kinds of melancholy and madness; and causes, according to GRIMM, RAU, HASENEST, MARDORF, HOYER, DILLENIUS, and others, similar sufferings. 204 Arnica montana has been given, from time imme- morial, against symptoms produced by severe contusions; according to MEYER, VICAT, CRICHTON, COLLIns, Stoll, and LANGE, it produces these symptoms in the healthy. According to HERMANN, VALENTIN, and others, ig- natia amara has often cured convulsions. BERGIUS, CAMELLI, and DARIUS have observed like symptoms from it on the healthy. Dr. KRÜGER, RAY, KELLNER, BOERHAAVE, and many others, practical physicians, have observed that stra- monium produces delirium and convulsions, and SIDENN, WEDENBERG, and others, cured delirium, accompanied by convulsive articular movements, with this drug. BAGLIO, BARBEIRAD, SPANELLA, DALBERG, BERGIUS, and others, have cured hæmorrhages through ipcca- cuanha, which, according to MURRAY, SCOTT, and GEOF- FREY, produces them. AKENSIDE, MEYER, BANG, STOLL, FOUQUET, and RANAE cured spasmodic asthma with it, which, according to MURRAY'S, GEOFFREY'S and Scorr's observations is produced by ipecacuanha. T. C. WAGNER observed how squilla maritima pro- duced pleurisy and inflammation of the lungs, and De HAEN, SARCONE, and PRINGLE, have cured these suffer- ings with it. Dulcamara causes convulsions according to FRITZE, and according to DE HAEN, they are cured by it. CARRERE observed large tettery eruptions as an effect of it, which again, according to FoUQUET, POU- PART, and CARRERE, were cured by it. According to P. ROSSI, VAN MONS, I. MONTI, SYBEL, and others, the sumach tree produces cutaneous eruptions, which gradu- ally spread over the body, and, according to Dufresnoy, and VAN MONS, it has often cured similar discases. R 205 According to MURRAY, cuphrasia cures inflamed and running cyes; and LOBELIUS remarks that it produces the same symptoms. According to LANGE, nux moschata proved very useful in hysterical fainting fits; and, according to SCHMIDT and CULLEN it produces (in large doses) in a healthy person, a loss of the senses and general insensibility. MURRAY, HILLARY, SPIELMANN, HOFFMANN, aud others, assert, that senna leaves cause colic, which DETHARDING cured with them. STÖRCK removed a general chronic eruption by clematis, and asserts, that this plant produces similar cruptions over the entire body. MURRAY and others, as well as daily experience, tell us that among the symptoms produced by tobacco, giddiness, nausea, and a sensation of anguish, are the chief ones; and DIEMENBRÖCK cured himself of these symptoms by smoking tobacco. HUFELAND cured a lethargy through opium, which, as is known, causes lethargy. It is equally well known that opium produces constipation, and LENTILIUS, TRALLES, WEDEL, BELL, HEISTER, RICHTER, F. HOFFMANN, and others, cured dangerous cases of constipation by it. With sabina, the severest abortive and hæmagogic remedy, RAU and WEDEKIND cured uterine flooding. CAMER- ARIUS, BACCIUS, D. HILDEN, FOREST, I. LANZONI, VAN DER WIEL, WEILHOFF, and others, assert that painful retention of urine and dysury are the usual and most painful symptoms of cantharides. FABRICIUS, CAPO DI VACCA, REIDLIN, YOUNG, SMITH, RAYMOND, BRISBANE, and others have cured with can- tharides very painful retention of urine, combined with dysury. 206 According to BEDDAES and others, nitric acid cures. salivation and ulcers in the mouth, which were produced by mercury. According to ScoTT, BLAIR, ALYon, Luke FERRIAR, and KELLY, it produces ulcers in the mouth, and salivation also. FALLOPIUS, BERNHARDI, RÖNNOW, and others, have cured cancer of the face with arsenic, which according to AMATUS LUSITANUS causes in healthy persons very painful tumours which are difficult of cure. According to HENRICH and KNAPE, it produces deep, penetrating, and malignant ulcers, and, as HEINZE observed, cancery affections. MARCUS cured an inflammation of the tongue and œsophagus very quickly with mercury, which, as daily experience teaches us and as DEgner, FRIESE, ALBERTI, EUGEL, and many others, have ob- served, causes inflammation and swelling of the interior parts of the mouth. DR. COPELAND says:- "Persons who are for any length of time exposed to the vapours of mercury, are, in general, afflicted with ulcers in the throat and mouth, also with painful diseases of the periosteum, of the joints, members, and sinews in particular, on having exposed themselves to cold, also with eruptions over the body, and all the sufferings which are generally described by the de- nomination of pseudo-syphilis. This is quite the picture of developed syphilis; and it is well known that mercury is considered the best spe- cific, and, as such, successfully administered in this disease. In the same manner, mercury was considered a specific in diseases of the liver; and Professor GRAVES says: "It cannot be denied, that abuse of mercury has caused disease of the liver." Dr. HEWSON directs the special attention of those who visit the Lock Hospital under his 207 direction to this point. It was then customary to sali- vate every patient, and to make him take mercury during several months; when the mercurial treatment was over, an enlargement of the liver often showed it- self. Iodine is recommended as an excellent remedy in salivation. According to ORFILA, it produces a horrid taste, heat in the throat, with a feeling of constriction, nausca, and salivation. China is recognised as a specific in intermittent fever. Jos. WITTMANN says, in his essay, which obtained the prize, that he found, by repeated ex- periment, it produced a disease resembling intermittent fever in the healthy body, therefore, quite in unison with HAHNEMANN's observations and experiments. As the adversaries of HAHNEMANN have taken all possible pains to combat the effect produced by china on him, and have asserted that HAHNEMANN suffered from indi- gestion through experimenting with china, and that thus naturally, the stated symptoms of cold, heat, and sweat (perspiration) would be explained, I will quote some allopathic authors on this very point. OSANN acknowledges that china has the power of producing fever, viz., HUFELAND'S Journal, vol. 61. Supplement, p. 97. In the Medical Review (March, 1840, p. 461) you can read one word more respecting a fact which we cannot pass over in silence, because it is attached to ideas which, in the interest of science, should be discussed, notwith- standing they appear homoeopathic. M. PIORRY denies the fever-producing power of chini- nium sulphuricum in healthy persons. However peculiar this effect may appear, we positively affirm having seen instances of the kind, and consider ourselves fortunate in being able to base our assertion 208 on the authority of M. HIPPOL. GANDORGS, a distin- guished military physician, who obtained, by experi- ments on himself, the result, that chininium sulphuricum has actually the power of producing real attacks of inter- mittent fever in healthy persons. If you want still further evidence of the unconscious application of the law of similarity, read HAHNEMANN's Organon. Edit. IV. f. 2-8, where you will find a great abundance of literary proofs. These are shining stars in the dark night of the Materia Medica, continuous examples of the more or less conscious application of the homœopathic principle; but being devoid of the in- dividual characteristic, they offered no fixed point of support, and as disconnected facts sunk into oblivion. For by physiological experiments alone are the treasures of the specific disclosed, by them only general remedies and these dispersed rays are concentrated into the focus of Similia Similibus, and only by this concentration do they obtain their very essence and peculiarity, and thus become worthy of scientific recognition, and fit for practical use. LETTER XIV. THE THEORY OF THE DOSE. THAT which ranks first and is most essential in Homœo- pathy, and remains valid under all circumstances, is the maxim "Similia Similibus." The first question is, therefore, what is the remedy which, according to the Homœopathic principle, corresponds completely with the symptoms of the disease? When this remedy has been found, then the next question is, in what dose should it be administered; this can, as a matter of course, only be solved by experi- ment, and cool objective observations, and HAHNEMANN and his followers resorted to these. HAHNEMANN first gave large doses, which differed in no respect from those prescribed by the followers of the Old School, thus Veratrum album was given in half, nay, even in four- grain doses at a time; Nux vomica, in doses of four grains, twice a day; Ipecacuanha, in doses varying from half down to one-tenth of a grain of the crude substance. Whilst prescribing in this manner, HAHNEMANN observed an aggravation of the symptoms belonging to the disease, and others in which he recognised the effects of the drug; and he, therefore, gradually diminished the doses, because he intended that drugs should work only in a P 210 sufficient degree to cure disease, without incommoding the patient by their evil effects. Thus experience taught HAHNEMANN, step by step, as it were, to diminish the doses. I will now explain to you, as concisely as possible, the technical process of which he made use to accomplish this. Of some substances, e.g., metals, different earths, salts, etc., one grain in the form of a powder is taken; this, together with one-third of ninety-nine grains of sugar of milk is put in a porcelain mortar, from the bottom. of which the glaze has been removed by scouring the mortar with moist sand; this being done, intermix the drug with the sugar of milk by means of a horn or bone spatula. Triturate the mixture during six minutes with some degree of strength; then clean the bottom of the mortar and pestle by scraping them (the latter must also be unglazed), so that all becomes intermixed, and then triturate it, without further addition, for another six mi- nutes, with the same force. To the powder thus scraped together, is added again in four minutes, the second third of the sugar of milk and the former process is repeated; then the last third of the sugar of milk is put to it, and the triturating and scraping process are again resorted to, so that triturating and scraping takes about an hour's time. In this manner, the first trituration is obtained. Of this you take one grain, mix it well with ninety-nine grains of sugar of milk, and triturate in the same manner as before, and by so doing, you become possessed of the second trituration; and from this second, the third is made in a like manner. Of this you take one grain and dissolve it in a mixture of fifty drops of spirits of winc, and fifty drops of distilled water, shaking the 211 phial violently. In this way we obtain the fourth dilu- tion. From this fourth dilution, the fifth is made, by adding one drop to ninety-nine drops of spirits of wine, shaking the phial in the same manner as stated above. Thus the sixth, seventh, eighth, up to the thirtieth and higher dilutions are prepared just as you may require them. Most plants are not triturated; but the tincture is prepared from the fresh or dried plant (if the former cannot be had), and is mixed with spirits of wine, and then strongly shaken; this is the first dilution. In a like manner, the second; and so on, the succeeding dilu- tions up to the one desired are prepared. Instead of this proportion of 1.99, that of 2.98, and especially that of 10.90, are used when preparing triturations and dilutions. To prepare the entire scale from the mother tincture up to the thirtieth dilution, we require thirty small phials, each containing 100 drops, which, in round numbers, amount to 3,000 drops, through which one, two, or ten drops of the one or other mother tincture have passed. Many opponents, in their zeal, calculated that the Baltic Sea was not large enough to contain the dilutions. of a single homoeopathic remedy. These gentlemen, in this instance, also, calculated without their host, as has often occurred before when attacking homœopathy. Their entire sea dwindles away into some ten or twelve tablespoonfuls of spirits of wine, which are intermixed with one, two, or ten drops of the medicine. Equally absurd is the assertion that a few drops of a remedy would turn the lake of Geneva into a homoeopathic dilution. Such intellectual opponents have been very 212 properly challenged to make a cask capable of holding the water of the Lake Leman, and to find a hand capable of holding and shaking it. The proportions have been thus specially detailed, to secure uniformity in the preparation of the medicines and certainty in their effects. It is therefore absolutely necessary, to state the pro.. portions which have been adopted upon each occasion. The remedies are given in drops, or sugar of milk and globules of the size of poppy seed are saturated with the remedy. They are administered to the patient either in a dry condition, or they are dissolved in water, which is often done also with the drops, and prescribed one teaspoonful or so per dose. Experience has shown, that many substances, which, in their natural state, produced but little or no medicinal effects in the human body, become by this mode of preparation, powerful and highly valuable remedies. Animal and vegetable charcoal, silica, gold, silver, lycopodium, common salt, sepia, copper, etc., also the most virulent poisons, such as arsenic, prussic acid, iodium, mercury, etc., are changed hereby into the mildest and most useful of remedies. Which of the triturations or dilutions must be given depends naturally upon the case under treatment, be- cause individualising is one of the absolute rules of homœopathy. Whatever has been said upon the subject are but hints, and these I will state to you as briefly as possible. In fixing the theory of the dose, these points have been, and are still under consideration: 1. The quality of the remedy. 2. The reactive power of the organism; and, 3. The nature of the disease. 213 As regards the first, it is apparent, that powerful poisons must be treated in quite a different manner from those that are less so. If arsenic, mercury, and iodium were to be treated in the same manner as chamomilla, euphrasia, the diseased organism would not be cured in accordance with biological laws; but it would be subjected to those of chemistry, and destroy the organism according to purely inorganic rules. If we prescribe successfully chamomilla in the first, second, or third dilution, we, in corresponding cases, on the contrary, would do vast mischief if we gave arseni- cum in the same potency. Poisons, as a general rule, must be administered in doses which do not arouse chemical forces, but merely give the specific individual impulse to the diseased organism, whereby the natural elements, according to their own organic laws, balance, by mutual self-excite- ment, the disproportion of their activity and products, and thus create health anew, as the final result of the received impulse. Arsenicum, iodium, mercury, etc., must, therefore, as a general rule, be given in higher dilution than chamo- milla, euphrasia, etc. Hereby it is not meant to affirm at all that cases do not occur in which these different poisous must be given in very low triturations or dilutions, and often in doses which, in ordinary cases, would cause a vast deal of harm; this depends often on the low state of the reactive power of the organism, and the nature of the disease. Still less do we wish to vindicate the assertion, that the mild substances should be administered in low dilutions, whereas poisons are preferred to be given in high ones. Practice clearly proves to the calm observer 214 that he seldom requires these lower dilutions, and that the higher, nay the highest, are amply sufficient to cure. It is observed with regard to the second point, the reactive power of the organism, that susceptible persons require less stimulants than those of a more torpid nature. This is the reason why children and full-grown people, sensitive, nervous, sanguine persons, can only bear (vertragen) higher potencies, whereas old men and phlegmatic, torpid individuals require lower ones. A great many exceptions, however, take place; and there are numerous cases where lower doses agree well with children, e.g., in torpid scrofula. Nor would it be consistent with the homœopathic maxim of individualising, to give a low potency to a fiery energetic old man merely because he is old, where- as the entire individual picture exacts a high potency. All that has been said with regard to temperament, sex, and age, whilst settling the theory of the dose falls into this category, inasmuch as these three points deserve attention only in so far as they pre-suppose a higher or lower degree of reactive power. It cannot be well decided beforehand what degree of reaction this may be. All we can do is, to repeat again and again the im- portant words: Consider all these points attentively, and individualise! HELBIG says, that he who establishes rules beforehand acts very foolishly indeed, for he undermines the very existence of Homœopathy. I mean that of individual- isation. The third point, representing the nature of the disease, coincides, strictly taken, with the second. For the reactive power of the organism is changed by 215 it in a certain manner. But it is worth while entering a little into its details. It is an old rule to give low potencies in acute, and high ones in chronic diseases; but there are also reliable authorities who maintain the contrary. He who is in daily attendance on the patient soon finds out that both rules contain so many exceptions, that they cease to be rules; and the practical physician will do well to indi- vidualise in the one instance as well as in the other. By doing so faithfully, he arrives at the indubitable truth, that he can and may cure both acute and chronic diseases with the entire scale from the crude drug up to the highest potency. This truth obtains confirmation in epidemical and endemical diseases, which have been impressed by the reigning genius, with a peculiar character. It also shows, that if the character of disease produced by this genius is erratic and versatile, it will be most profitable, as a general rule, to give high potencies, whereas those of a torpid character require low ones. It will not be out of place to quote here two sentences that have been expressed with regard to the magnitude of the dose, viz.: the closer the resemblance between the effects of the drug and the symptoms of the disease, the smaller may be the dose; and the less they are alike, the larger should be the dose. Experience, however, has taught us, with regard to the first sentence, that the choice of the potency depends on the reactive power of the organism or on the GENUS EPIDEMICUS, even where the remedial effects closely resemble the symptoms of the disease. The remedy should never be taken alone into con- sideration, but the organism should be consulted above 216 all things. It is true, that it is stimulated in a peculiar manner by the remedy; but it completes the cure accord- ing to its own organic laws. The second rule, viz., that of a less similar remedy a larger dose should be given, means nothing else than that quantity should replace quality, a remark which reminds us of the bulks of the old school, and cannot be sufficiently condemned as being both false and hurtful. If you collect all that has been said, you obtain as the result of present experience, that only general but no individual rules can be laid down with regard to the dose, and that it is inadmissible to give a direct prefer- ence to either the lower or the higher potencies, as in this case also everything must be individual. From this it results, that no nominal dose exists; for it would con- tradict daily experience and weaken the homœopathic maxim of individualising. It is, therefore, evident that absolutely strong or weak doses, such as are constantly mentioned in the old practice of medicine, do not exist in reality; but that that dose is always the strongest which has the power of changing the diseased state to a healthy one; therefore in some cases a lower, and, in others, a higher potency is requisite. In Homœopathy (where all depends upon indivi- dualising) there can be no question of either. Daily experience proves that the entire scale from crude drugs up to the highest potency must be open to the physician, that he may choose the suitable dose in each individual case. It is not proper to seek success alone in the lower or higher, or only in the highest of potencies. Conse- quently, homœopathic doses are not merely the higher 217 and highest potencies, but also the lower and lowest, such as the mother tinctures and primitive triturations, which latter are especially recommended in the Materia Medica of NOAK and TRINKS. These lower ones contain such a quantity of the drug, especially if prepared in the pro- portion of 10·100, that it can be at once recognised by the smell, the taste, and sight, or by a chemical re-agent. In the first trituration, the very poisonous substances, such as arsenic, prussic acid, sodium, nux vomica, etc., contain such considerable quantities of the drug, that they may be called large even according to the views of the Old School. If homœopathic doses are, therefore, put down as nought, this is a proof either of the greatest ignorance, or the most subtle distortion of the truth to prevent the attainment of certain aims in view, such as professorships, etc., yet these are the idols before which the Baal-priests of material egotism constantly bow down. Truth is of little importance to them; in that which operates only do they take an interest; and it is cer- tainly a great condescension of these gentlemen, if they, at any rate, oblige truth to be the bearer of falsehood. Closely connected with the theory of the magnitude of the dose is that of its repetition. Listen to what HAHNEMANN says on this subject. If the physician is convinced that the medicine has commenced operating, he should not repeat the dose, or, at all events, be very prudent, and wait rather until the favourable effect ceases; he then should repeat the dose, or give another remedy, as circumstances may exact it. He should prescribe another remedy, when the symptoms of the disease have so changed that they require another remedy, corresponding in its effects with the present state of disease. Frequent unnecessary repetition of the 218 dose often impedes its salutary effects, or aggravates the disease. This declaration, observe, is the pure impress of quiet objective experience, and confirms the truth, that the true physician is characterised not by doing a great deal, but by doing well what he does. This doing well must naturally, in each separate case, be left to the judgment of the physician, for here also the first law is to individualise. As a general rule, it will prove useful to repeat the dose in acute, and to wait some time in chronic dis- eases before doing so; also, further, that the duration of the remedial effects mostly depends upon the peculiarity of the disease, on the strength of the effect, on the nature of the drug, and on the potency. To enter into details would exceed the object of my communications, as it belongs to the department of Special Therapeutics. LETTER XV. THE MINUTE DOSES OF HOMEO- PATHISTS. A LADY of a phlegmatic disposition, and who is inclined to weeping suffers several weeks from the most severe prosopalgia, of a jerking, tearing kind. The attack comes on every evening, about six o'clock, and in- creases in violence up till midnight. The pain is aggra- vated by lying down and by heat, and ameliorated on rising, and by cold. All possible methods and remedies had been tried in vain. Despairing, she at last consults a homœopath; he gives a drop of the ninth dilution of pulsatilla, and no further attack occurs. Somebody else had been suffering for more than three months from most severe rheumatism of the joints. They are swollen, white, very painful on moving, and to the touch, and, in addition to this, a painful retention of urine has set in during the last days. All that the old school could offer had been tried. Suffering the most acute pain, and being utterly helpless, he sent for me, about seven in the evening. I gave him one drop of the ninth dilu- tion of bryonia: the other morning I found my patient 220 almost free from all pain; over night, a very copious flow of urine had occurred, and since then the secre- tion of urine had been easy, and in proper quantity. Eight days afterwards, he was completely cured. To a child one year old, with hot forehead, ruddy cheeks, dry, burning skin, and who had not slept since three days, but had been crying nearly without a moment's intermission, I gave, in the evening, about eight o'clock, two globules of calcarea carbonica, thirtieth dilution. About nine it fell asleep, slept well during the whole night, and was well the following day, and re- mained so. Such cases every busy homoeopathic phy- sician can tell you by the dozen. Cases of the most wearisome diseases, which had re- mained unchanged in spite of all dietetic regulations, nay, had even become worse, and, for this reason, been pronounced incurable, were cured in a most striking manner as soon as the least dose of the appropriate homœopathic remedy was given. These are facts, which everyone who experiments in the prescribed manner and goes to work with an un- prejudiced mind, can repeatedly observe, facts which cannot be denied by a priori reasons, and which are not untrue because they go against, or rather ABOVE the reigning notions and theories. Here, as everywhere else in physical science, theory must follow fact, and is it not utterly false, unscientific, and completely against the spirit of true natural philosophy, to recognise a fact because it is opposed to the one or other of reigning theories. It is clear that he only who has experimented in a faithful and honourable manner, can form part of the jury who have to judge experiments, as they alone are 221 decisive, and it is a maxim that one positive is worth more than a hundred negative ones, for it is not always in our power to create all the conditions required for a positive experiment. The result of an experiment may therefore be quite trne, and undoubtedly often is so, even when other investigators do not succeed in ob- taining it. This high and unapproachable law of the investiga- tions of nature, viz., to try the experiment by a counter experiment, is completely trodden under foot by phy- sicians in respect to homoeopathic doses. Instead of ex- perimenting, they deny, and whilst in their ignorance they consider the dose, and in particular the smaller and smallest ones, as being the very essence of Homœopathy; they imagine that by denying the efficacy of small doses they have given the very death-blow to Homœopathy. But you have been told that Homœopathists use the entire scale from the mother tincture and original trituration, up to the highest potencies (therefore, in an allopathic sense, use large and small doses), that the main thing is the bearing of the remedy upon the diseased organism; that is, its quality; and that the quantity of the dose is only a necessary result of the quality, that the Homœo- pathist, therefore, is fully justified, if he prescribes large and small doses, according to quality. The natural conclusion, therefore, is, that small doses constitute least of all the very nature of Homœopathy, but that they are only a subordinate deduction from the quality of the remedy. Strange that opponents have constantly attacked with ungovernable fury small doses, which have always proved efficacious when honestly tried, and that they have disposed of their validity, although they consider analogical facts in natural philosophy, chemistry, and 222 the other branches of physical sciences comprehen- sible, and do not hesitate a moment to explain the several complaints, such as epidemical diseases, from some spiritual power or other, which is imperceptible to the senses. It is our opinion, that if such a power can so strongly affect the healthy body as to make it ill, that it is far more possible that remedies, the material ex- istence of which has been proved, even in high dilutions, by SEGIN and MAYERHÖFER, can force sick bodies to a reaction, from which health results. To accept the one and reject the other is not logical; and the proverb, "We believe in what we wish for," may be with propriety applied to these gentlemen, by saying, they do not believe in what they do not wish for. The investigations of SEGIN and MAYERHÖFER arc too important to be passed over, for they have proved the material existence of drugs even in the highest dilutions. On this account, I consider it my duty to enter on some of their details. As far back as the year 1838, SEGIN ex- amined the first six triturations of copper. He asccr- tained, by means of a microscope, which magnified seventy-five times, that the black-brown globules of cop- per were distributed equally through the sugar of milk; but in the seventh trituration he was unable to discover the least trace of them. To complete these investiga- tions, he experimented with carbo vegetabilis, cuprum metallicum, cuprum aceticum, as well as muriate of ammonia; and he affirms, that he traced the presence of these drugs even in high dilutions. These results were confirmed by MAYERHÖFER, who extended his ex- periments still further, and adopted a more scientific mode of going to work. His intention was, to examine more closely the pro- 223 cess of real attenuation produced by trituration; to follow up the divisibility of matter, as far as possible, and to gain hints for practical pharmacy. To do away with all delusion, he examined with PLOZL's solar microscope, first the sugar of milk, then the alcohol, distilled water, and even the glass slide, upon which the objects rested. After having done this, he examined his own preparations (2·98). Foliates and fine precipitates were used to obtain the metallic triturations. He discovered platina even in the tenth dilution; seven to eight minims, according to microscopical calculations, being separated from each other by of a line. 1 1 20 In like manner, he traced mercury, precipitated metallic gold, silver, and copper, in the tenth dilution. Iron in the eighth, precipitated gold in the fourteenth. When mentioning gold, he calls attention to the fact, that a gold ring rubbed on a hone, leaves millions of particles of gold behind, and that these are visible. under the microscope. These experiments have been conducted in so careful and comprehensive a manner, that there can be no doubt as regards their exactitude. MAYERHÖFER, moreover, proves that the metallic par- ticles become gradually smaller in every trituration, and he indicates this proportion by numbers, which clearly show, that it is only the imperfection of the instruments that prevent us from discovering the metallic particles even in higher dilutions; and that minima will be traced even in the highest dilutions, when instruments have become more perfected. He infers from this, that by trituration, substances are constantly split into smaller and smaller particles, and become more fit hereby to enter the body; that the 224 process of trituration is a development, a setting free, as it were, of the medicinal powers; and that this is always accompanied by a certain excitation of electricity and magnetism. The destruction of metals of the Old School is, accord- ing to MAYERHÖFER, rather a vivifying of them. Accord- ing to him the patient receives, in one grain of tin, of the third trituration (2.98), 115,200,000 divided, and still further divisible, metallic particles. These experiments have given him the following results-Precipitated tin can be divided, physically, a quadrillion times by trituration; precipitated copper, pla- tina, silver, gold, above a trillion times; liquid quicksilver, a billion times; foliated tin and copper, above a billion times; filed or foliated lead, and filed iron, a billion times; coarse tinfoil, foliated silver and gold, a million times. According to him the diameter of a small metallic atom equals 1200 to 2000 of a line, so that the cubic contents of a metallic globule are at least sixty-four times smaller than the blood-globule of a human being; this proves that the finely distributed metallic globules penetrate freely all the structures and tissues. In this manner, MAYERHÖFER followed up the divisi- bility of matter, and proved that it exists even there where opponents supposed it gone for ever, and conse- quently inefficient. As the blood completes its circulation through the body in about twenty or thirty seconds, the finely dis- tributed globules come into contact, in this short space of time, with the extremities of the nerves, and thence arises the quick and powerful medicinal action; for, according to the best observers, medicinal effects do 225 emanate more from the extremities of the nerves than from their centres. This agrees with the conclusions which PANIZZA arrived at from his experiments on absorption. They showed him, that absorption goes on more readily the more soluble, distributed, and easily to be assimi- lated the substances are; that therefore repeated small and soluble doses of medicine are more efficient than large ones, which, when in an insoluble state, leave the body through the evacuations (Bart. Panizza, dello absorbi- mento venoso. Milano, 1843-4). Professor ALBERS expresses himself in a similar manner "The divided (small) dose is better tolerated by the stomach, it irritates the points less, it is more casily absorbed, and is therefore far more complete and lasting in its effects then the full (large) dose." SCHULTZ says, "The absorption of drugs is more hastened, the less the local irritation of the absorb- ing organs is; consequently, the smaller the dose.” COINDET says, "That oxalic acid kills quickly when very much diluted, because it is easily absorbed. In a concentrated solution, it causes inflammation of the stomach, and, without being absorbed, kills only in con- of its grosser action. sequence of its The same is the case with arsenic." The easier the absorption, the more certain are the effects of drugs. With homeopathic remedies, this absorption is so com- plete that particles of the drug reach the innermost tissues, and can there influence the essential acts of life. The assertion, that such small quantities cannot affect the living organism, is therefore simply ridiculous; for they are most fit to influence the innermost process of life, ૨ 226 as practice shows. This also confirms the fact, that, under certain conditions and circumstances, similar results will occur. These conditions, however, are necessitated partly by the organism and partly by its relation to the remedy. Physiology recognises that living organisms, and that of man above all others, are far more sensitive to certain influences than the chemically acting bodies. BADGE says, 'In the diseases of man, we often meet with an astonishing sensitiveness in the nerves of motion and in those of sensation. The conditions which cause a nerve to become so sensitive a reagent are not exactly known." He clearly proclaims the fact, that the diseased organism is an extraordinarily sensitive reagent. If he had made experiments with drugs in the same. way that homoeopathists do, he would have discovered a great many conditions, which cause the organism to be- come so sensitive a reagent. For herein the Physiological Materia Medica of Homœopathists has far outstripped Physiology; and the latter may learn a vast deal from the former, and can receive from it a great many explanations respecting the reaction of the Organism to external influences. Even PFAFF, who is the most strenuous supporter of the Chemical Materia Medica, asserts that the living organism is in every respect the most sensitive. reagent, and that it indicates by its changes the smallest differences in the degree and quality (of affinity), even where chemistry is powerless. And reality confirms this! For who ever weighed, or discovered by a chemical reagent, electricity, galvanism and mesmerism, which influence the human body in so 227 powerful a manner? Who ever weighed the miasma of scarlet fever, of the measles, of typhus, of cholera, of the pest, or of any other contagious disease? Who ever weighed fear, fright, joy, anger, which often cause paralysis or an apoplectic fit? Who weighed the thought, which so powerfully penetrates all forma- tions of matter? Who ever weighed the marsh miasma, which destroys armies and depopulates entire provinces? Who ever weighed grief, sorrow, and care, which undermine the powers of both body and mind? Whoever weighed the vapours of lead, which cause colic and paralysis? Who ever weighed those of mercury, which produce the most awful of ailments, the mercurial disease? Who ever weighed the vapours of phosphorus, which cause caries of the bones in those exposed to it? Who ever weighed the exhalations of the poisonous Sumach trce (myrtle-leaved Sumach), which produce eruptions, fever, and other complaints, in those who approach it? To what do the emanations from flowers amount, which, when they pass into the body, produce giddi- ness, fainting, nausea, nay even apoplexy? Globules of pure mercury are boiled in a large quantity of water; and this is prescribed by many clever Physicians against worms. No diminution is perceptible in the weight of the mercury, and nevertheless the water has proved curative. How much poison enters the body from the bite of a serpent, or the sting of an insect, a poison produc- tive of painful, nay often dangerous, symptoms? How intense is the effect of the poison contained in the saliva of mad dogs, the weight of which has never been ascertained? 228 HUFELAND informs us that a piece of opium held for a length of time in the hand produced all the narcotic symptoms belonging to this drug. HILDE- BRAND relates that a whole troop of hussars were seized with vomiting, headache, and giddiness, because they had tried to deceive the Custom House officers by smuggling tobacco, and hiding the leaves on their chests and abdomen. DICKSON carried a specimen of Elaterium home in his hat, and was seized in a quarter of an hour later with severe head-and stomach-ache, and with colic symptoms which recurred under paroxysms of fever. How trifling a quantity of Vaccine Virus is sufficient to produce a specific disease, which, for a certain number of years, protects against smallpox. Thousands may be vaccinated from a single pock. Listen to what CARL VOGT says upon the subject. If we consider that the minute quantity of cow-pox virus introduced into the blood by vaccination produces inflammation, fever, general ill-health, and formation of pock, as direct consequences, and that its indirect result is the removal of the predisposition towards this dis- ease; if we consider that the blood is so little changed hereby that neither microscope nor any chemical re- agent have been able to explain it, we must acknowledge that, in spite of all our careful investigations, we are unable to explain scientifically the changes which are and may be produced in the blood by bodies so minute, that they cannot be pointed out either by chemistry or the microscope. — (Physiological Letters, pp. 52, 53. 1854). Here we meet again with the candid acknowledge- ment, that the smallest trifling cause which we cannot discover in the blood, is productive of the most powerful 229 effects. DR. SIEMERS is quite right in saying, that the sensuous nerves are affected by a minimum of specific irritation. The physiology of plants perfectly agrees with this; and teaches us, that the smallest quantities of colouring matter produce extraordinary effects; and that trifling changes in the mixing of substances, occa- sion such wonderful manifold shades in the brilliancy of colour, that the quantity of the determining influence of the matter remains generally far behind the shining splendour which strikes our eye in the blossom. And The same is the case with smelling substances. Here, again, we find a comparatively small quantity of matter productive of powerful effect. The strength of the scent may not be judged, even by the quantity of the etherial oil. So does the hyacinth contain but very little of this oil, in spite of its very strong scent. what powerful effects do not smelling substances pro- duce in the human body, notwithstanding their trifling quantities! Dr. GÜNTHER asks, therefore, in quite an astonished manner, why no importance is attached to the weight of the scent which is used to awaken persons out of fainting-fits, when, on prescribing for the stomach, everything turns upon substance and quantity? Dr. SNOW of London seems to coincide with him, for he has endeavoured to administer most remedies in the form of vapours through the respiring organs. The great sensitiveness of the human organism to certain external irritants manifests itself, especially in idiosyncrasies, the cause of which is sought for in a peculiar mixture, and whereby the organism finds itself in a peculiar state, so that the most trifling irritants cause unusual, strong, nay, even violent, reactions. The nature of idiosyncrasies is unknown; they cannot 230 be traced back to material conditions; their peculiarity and speciality can only be recognized by the disturbance of the functions. Here are a few examples. Eating quails causes in TISSOT relates of a friend, that the smallest quantity of sugar made him vomit, even when administered to him without his knowledge. DEJEAN mentions a man to whom honey acted as a poison, whether he took it inwardly or applied it outwardly. WHYTT attended a woman who became sick on applying the smallest portion of nutmeg to the body. many individuals cramps in the legs; while eating larks causes cramps in the arms. Four sisters, who, before puberty, were very fond of strawberries, and partook of them without suffering any bad effects, could not do so after the catamenia had set in, without being affected with erysipelas, swelling of the whole body, convulsions, noise in the ears, and insensibility. The celebrated DE HAEN could not eat half a dozen strawberries, with- out exposing himself to convulsions. I know two robust young men, who, when they have eaten a few straw- berries, become covered from head to foot with the most violent nettle-rash. BOYLE says, that he knew a man who became ill every time he passed by a coffec- house. GAUBIUS knew a person, in whom lemon-juice produced a tremor of the whole body, whether applied to his hand with or without his knowledge. MAGNUS STRÖM speaks of an inhabitant of Leyden, who could tell when a drop of lemon-juice fell on his hands, though his eyes were bandaged, and his hands laid on his back. He was unable to distinguish any other fluid. AUTHENRIETH confirms, that a piece of copper laid on the hand, causes in many persons, the most serious symptoms, such as convulsions of the extensor muscles, 231 etc. GAUBIUS knew persons who could not live in the vicinity of cherries. MOSTHOFF mentions the case of a child, who was seized with the most violent nausea and vomiting after eating a single cherry. The proximity of a cat or magnet, often causes the most curious effects in nervous persons. In the same manner as in idiosyncrasies, a great sensitiveness exists for certain stimulants, so do we find the same in all bodies for drugs, if administered in proper doses. The Physiological Materia Medica affords us everywhere proof of this. They affect some organs, systems and tissues, in a certain manner; so that there exists between them and the parts of the organism which they affect, the same necessary relation as exists between the organic foundation of the tissues and the inorganic tissue-formers. Professor VOGEL says, therefore, very justly: "If the regular inorganic component parts of men and animals exercise and undergo a legal attraction in proportion to the organic formation of the body, so is such a relation not wanting in those substances which are incorporated into the body under peculiar influences, be they food or drugs." Pathology teaches, that the sensitiveness of the organs to specific stimulants, increases to an extra- ordinary height when affected by disease, so that their proportion stands to those in health as 1 does to 3,000. For this reason are the physiologically-tried homœo- pathic remedies felt in the smallest doses; and so do they call forth re-actions because they affect the suffering organs in exactly the same manner as disease does. A few better known examples may explain this. The organs of hearing, in health, are generally but little affected by the roar of artillery; but if they 232 are inflamed, the most gentle footstep on the softest carpet occasions pain to them. The eyes, in health, can bear the brightest sunshine; nay, this is both food and pleasure for them; if inflamed, they are painfully affected by the least ray of light. The healthy stomach can bear the coarsest food; if inflamed, it refuses the smallest quantity of everything that is of a solid or liquid nature. Here sound, light, food, the necessary stimulants for the ears, the eyes and the stomach, are hardly tolerated in disease, even in the smallest quan- tities. The same thing happens in all organs, and the drugs which act upon them; therefore, as a rule, it requires but small doses of them to call forth healthy reactions in the organs affected by them; by repeated stimulants, or too large doses from the very com- mencement, the positive effect changes at once to the negative one, as physiology and pathology sufficiently show. It is evident from this, that a dose which is suitable for the patient, can be taken without producing any effects whatever by the healthy; and those who, in their anxiety to prove the inefficiency of the small doses of Homœopathy, offer to swallow the contents of a phial, or of a small medicine-chest, do not, by this vain boasting, prove the inefficiency of Homœopathy, but only their own great ignorance. For, in the human body, we find the confirmation of the law, that the greater result of some influence depends more on the susceptibility of the body which is exposed to it, than on its own peculiar strength. As the glass can be made to vibrate even to falling, and tremble at a single and, comparatively spcaking, faint sound of the violon- cello, with which it sympathises, although it resists 233 the crashing influence of an entire band, which does not touch its keynote; so will every sounding body harmonize in power and quickness with the vibrations of the sur- rounding air, to which it is susceptible, and will infallibly be incited to a similar vibration, thus demon- strating the so-called sympathetic sounds. In the same infallible and powerful manner do the least incitations of the specific remedy, which corresponds with the morbid susceptibility of this body to certain movements and ma- nifestations, show themselves. The sanitary Councillor RUMMEL is, therefore, perfectly justified in saying: "The severer the disease is, the less is the susceptibility of the organism to extraneous influences; and the greater its susceptibility to irritants of a similar nature." The dose of the homœopathic remedy should, in such cases, be only a very minute one-if the body, which is already morbidly sensitive to its effects, is not to sink under its primary action-if the vessel, which has been incited to sympathetic vibrations is not to burst — if death or medicinal disease are not to occur. This is recognised as valid and well-known, with regard to the sensitive nerves; the notion which calls forth the change that occurs here facilitates this. If physiologists would only closely study the physiological materia medica, they would soon discover, that the nerves representing nutrition possess, when in a morbid state, an equal degree of sensitiveness to certain specific irritants, as belongs to the nerves of sensation, and that the incite- ment which calls forth the nervous action, is not so unknown as they fancy. They would, moreover, find VIRCHOW's remark confirmed, viz., that not all the phenomena of irritation should be attributed to the nerves; but that many owe their origin also to the 234 other vital elements; and that these, therefore, possess, like the nerves, their specific stimulants, which belong to them by affinity, and also an equally increased susceptibility for them in disease. Hence the efficacy of these specific stimulants; even in the smallest dose, in whatever system, organ or tissues, the morbid uneasiness or material change may happen. If it be now said, that if such doses produced any effect, man would be every moment exposed to disease, in consequence of the medicinal potencies contained in the atmosphere, in the water, etc., so is it overlooked, that the small dose is only the more effective, when there exists the necessary specific affinity between the organism and the remedy. If this is wanting, no effect takes place. This is the reason why, during the most immaterial and dangerous potencies (I mean miasm and other contagious disease), those persons are first of all attacked who have a specific suscep- tibility for them; whilst others, in whom this pre- disposition does not exist, escape with impunity, though equally exposed." The following words of VIRCHow seem here in their proper place: "Upon a substance capable of incite- ment, not only a general vital motion, but also a fixed direction, can be transferred. Wherever real substances are to appear in the body, such as catalytics, they must previously enter into the circulating fluid, and be led by it to the various parts; especially to the central tissues of the nervous system. The irritation will be more or less severe, according to the intensity of their inward motion; it may soon pass over, or last a very long while. In the latter case, it is beyond doubt that all the processes of life, the bodily as well as the mental ones, may obtain, through this, a fixed deviating 235 direction, in the same manner as occurs with the action of the spermatozoa-fluid upon the ovum. It should not be overlooked, that THE AFTER EFFECT may last any length of time, e.g., as in syphilis. The original irritating substance has, perhaps, long disappeared out of the blood; nay, what is more, perhaps no characteristic change is at all found in the blood (according to VOGT, with regard to the blood in small-pox); and, neverthe- less, does the direction of the processes of life remain nearly always unchanged. The formation of the blood is then by no means a constant, the dyscrasy only an ephemeral, one. The deviation of the after-effect can only be supposed to depend on the intensity of the inward motion of the incitor, and not upon the quantity of the same, for between the inward motion and the quantity (volume of the different incitors), there evidently does exist no fixed proportion. A minimum of a very ener getic excitor may, on the contrary, possess very great and lasting effects, since the primary catalytical action may be propagated further and further. This is one of the facts which demonstrate the possibility of so-called homœopathic effects. Yes, and this catalytical action takes place the more intensely, the greater the specific relation is between the remedy and the organism, or any of its parts; so that it is actually this proportion which determines the degree of irritation, and the remedy which is homœopathically indicated, is also the strongest, viz., causes the most powerful stimulations. In this proportion, however, as you have been told, the one factor is represented by the incitor; whereas the second greater and more important one is represented by the susceptibility of the organism towards the former." 236 occur. This demonstrates the efficacy as well as the necessity of the small dose, without which over-stimulation would SCHULTZ expresses himself in much the same manner: "It is very improperly supposed, that the proportion and magnitude of the effect are entirely dependent on the dose; and it is forgotten that the organic effect of the drug is only an imparted vital incitement, the magnitude of which is not so much determined by the magnitude of the dose, as by the extent of the organic development of the action of the body, to which the remedy only incites the functions. In the same manner in which scarcely-to-be-weighed atoms of carburetted hydrogen gas, and gas of ammonia, in miasms, can cause the severest forms of disease in our body, so also can smaller doses of medicine produce great effects in it, if they duly come into contact with the organs which they affect. And Homœopathy teaches us this right mode of bringing drugs into contact with the organs with which they stand in specific relation, and hence arise the powerful and striking effects produced by the minute doses of homeopathy." Whilst considering the minuteness of the doses of homoeopathic medicines, we should not lose sight of the peculiar manner in which these medicines are prepared. It is well known that every body possesses certain physical and chemical peculiarities, which do not all of them appear at once. This depends upon its relation to other bodies, or that of its parts among each other, or of both combined. If a change happens herein, as a matter of necessity, some other or stronger effect results. But the triturating and shaking causes con- ditions whereby bodies, which in their original state produce hardly any effect upon the human organism, 237 become drugs possessed of the most curative properties, as is the case with lycopodium. Others again are changed from destructive ones into the mildest, which free life from the shackles of disease; as is the case with arseni- cum. The larger effective surface of the drugs obtained by trituration and shaking, play an important part in this. Professor DOPLER, of Prague, the great natural philosopher, throws a beautiful light on this subject. In an Essay entitled, " Of that which is Great and Small in Nature," and which was published in the "Journal of Natural Philosophy and kindred Sciences," edited by Pro- fessors BAUMGÄRTNER and HOLGER. These philosophers do not believe that any one is justified in determining the effect of drugs according to their bulk or weight, but from the extent of their acting surface. His words. are as follows :—— "The ideas, great and small, are of a very relative nature; and it depends alone upon the right choice and the absolute magnitude of the fundamental unity, whether anything is to be called great or small; these are truths which now-a-days are met with in the mouths of nearly everyone." Nevertheless it does seem, that, as far as the appli- cation of bulky unities is concerned, less importance is attached to the above, in science, than might be expected under existing circumstances. For how could it otherwise be explained, that we often hear (without there being the least justification for it), that certain things are said to be extraordinary, nay, vanishingly small; which according to another (to me, quite rational) view, might with perfect justice be called large; nay, even extraordinarily large? As I express in the very face of science so harsh a 238 sentence, it is my duty to explain my reasons for saying so; and I believe (without being called upon to do so), that I can best do it by proving the above assertion on a concrete example. But the fact, that the point at issue accidentally comes in rather close contact with a subject which has been frequently alluded to of late, nay, which has been turned into ridicule, forces me from the very commencement to the declaration, that I do not write in favour of any indivi- dual notion, or do I wish it to be understood that I have given my opinion with regard to the above new doctrine. Some faithful followers of the old school, on the con- trary, especially requested me to publish this view, as they considered it of sufficient importance to see the following argument combated, or have it confirmed if the first could not be done. It is a truth which cannot be denied, that weight affords a fit and very easy standard to tax the magnitude of a great number of effects, as is chiefly the case with everything ponderable. But we should go too far, if wc took for granted that the unities of weight would suffice to explain all the modes of the effects of bodies. The very effects of galvanism must be determined by something different from weight, leaving many other effects of nature out of the question. Ere we are permitted to pass a thing off for either great or small, or that we classify it among that which is chimerical, on account of its supposed insignificance, the fundamental unity should, according to my opinion, first of all be proved, so as to determine whether in judging it we should employ scales or a yard-stick. In considering this as it should be done, and return- ing to the above proof, I, by way of example, put 239 the following question: With what right do we deter- mine the effects of drugs according to their weight, and not rather according to their effective surface? Or, in other words, Is it the interior of a drug, or are its out- ward parts those which come in contact with the sensuous world, that determine its medicinal power? And if the latter be really the case, or only conceivable, how does. it then stand with the supposed smallness of some doses of medicine, apparently reduced to nothing. Not caring about an immediate decision of the first- mentioned double question, I can for the present con- tent myself with the general admission, that bodies, perhaps, work only in so far medicinally as they possess surface, or can themselves become one. By the physical surface of a body, in contrast to the mathematical one, we understand the total amount of all those minima which, in one direction at least, are surrounded by minima of another kind. The direct result of this is, that bodies, which are broken or made smaller by any other process, must vastly increase in surface, inasmuch as minima which formerly belonged to the interior of the body come now in contact with the surrounding medium, and form immediately part of the new surface. Just as apparent is it also on the contrary, that two or more bodies of the same kind, which formerly formed a whole, or which otherwise fit exactly on being brought together, lose their mutual surface, at least at the real points of contact. A somewhat closer inspection of this subject leads, moreover, to the result, that the surface total increases at least in exactly the same, and frequently even in a greater, proportion, as the diameter of the separate particles becomes smaller. If, therefore, e.g., a cubic 240 inch of the one or other body is pulverised to the extent of a somewhat coarse sand, by which means it is crushed into more than a million particles, its surface, as an easy cal- culation teaches, will have increased, and will extend over at least six or seven square feet. Microscopical examinations show further, that a grain of the sand above alluded to, is several hundred times larger than the still perceptible particles of lime, flour, and dust, which float in the air, as well as those of many other pulver- ized bodies, such as nature and art frequently exhibit them. If the body alluded to, therefore, be triturated to a powder of like fineness, the total surface would pre- sent an area of more than a thousand square feet. In order, however, that the above-mentioned surface may appear as a physical or effective one, it should, from the very beginning, prevent the single particles coming in any contact whatever among each other; which, according to my idea, cannot be done in any other manner than by mixing the substance in question from the commencement, with another extraneous body, e.g., sugar of milk, and triturate them both together. The medium, or the vehicle alluded to, must be ad- mixed in sufficient quantity. This concerns liquid bodies even in a still higher degree, as their smallest particles might not be of a polyhedrous (as is the case in inflexible bodies), but of a globular form, as their great moveability justifies us in supposing. The writer of these lines permits himelf to raise here the not altogether unfounded conjecture, that trituration, or the process of rendering bodies smaller, itself may, perhaps, be carried to a limited degree only, inasmuch as very finely triturated bodies seem to adopt gradually the property of shifting in an casy manner, which 241 belongs otherwise only to liquids. In an explana- tory essay on Galvanism, I proved years ago, in an à priori manner, not merely the necessity, that bodies must pass over into an electric state by alternate con- tact, but also that this happens in every instance where a body is diminished in size, and have, to the best of my belief, explained several phenomena in a simple and satisfactory manner. This being established, there remains no further doubt, that in so uncommonly increased a surface, the quantity of free electricity must increase in a like degree, whereby it then frequently happens, that, under especially favor- able conditions, e.g. whilst grinding crystalline sugar, the electricity accumulates on the surface, and does so to such an extent as to cause an appearance of light. Notwith- standing, it may be considered certain, that the electri- city which appears in such enormous quantities during the process of trituration has so little tension that empty space and nervous substance, perhaps the best con- ductors, can act only in a derivatory manner on it, but that neither metals nor other bodies can do so. In passing it may be observed, that if the two triturated bodies are closely related in a chemical manner, a chemical combination may result through the ever-increasing surface of contact, and that the explosions, which sometimes happen during trituration, are not so much to be attributed to the generation of heat as to the chemical affinity which has become active in consequence of the thus extraordinarily enlarged surface. This shows that a drug, the inward surfaces of which have been unlocked, as it were, by trituration, offers more points of contact to the body after trituration R 242 than before; and that it is, therefore, more fit to com- municate its peculiar mode of movement to the suscep- tible carrier-the specifically related parts of the organism, and so develop its power. It is, moreover, clear, that the small dose in its liberated condition can better effect this than the large dose of the latent state. If, besides, we consider the following observation of AUTENREITH, "that the effect appears always greater than the cause," in all that is organic, for the simple reason, that the organism transmits further move- ment communicated to it; according to its own laws, one cannot help being justly astonished, that a truly natural philosophic mind should wonder at the efficacy of small doses. Listen also to LIEBIG about "large and small." We know that animals possess teeth, organs of digestion and motion, that are invisible to the naked eye. There are others which are not immeasurable, but which can be measured, many thousand times smaller, and which possess the same apparatus. Like the larger and largest ones, they eat, and propagate through eggs, which are again many hundred times smaller than their own bodies. THE IMPER- FECTION OF OUR EYES ALONE PREVENTS US FROM SEEING ANIMALS THAT ARE A BILLION TIMES SMALLER." -(Letter on Chemistry, Heidelberg, 1844, f. 28). ARNOLD adds, in an inquiring manner: "If thesc small animals and their still smaller parts of formation possess life; if they are active in their way; why should we, then, deny the efficacy of small doses (which, according to MAYER- HOFER), are still visible?" Who will venture to main- tain, after this, that the usual ideas of large and small are sufficient to explain the efficaciousness of substances? Do we not find, the more we penetrate nature, that life 243 * has constructed its real laboratory, in the most delicate and innermost parts, and that substances are the more vital the more they pass from the coarse state into the more refined one? Are not always the finest and smallest particles the real carriers of life, and therefore the most effi- cacious ones! MAYERHOFER has shown, by experiment, that particles of these drugs are perceptible to the senses even in high triturations, and DOPPLER has ingeniously elucidated this. The assertion that high tri- turations do not contain particles of drugs, because the divisibility of matter does not extend so far, is unfounded, and for this reason to be rejected. For physical and mathematical divisibility is endless. It is true, that the practicability of the first depends upon the instruments and on our skill; and will, as a matter of necessity, increase in proportion to the increased perfection of both. It is, therefore, ridiculous to attempt to limit the skill of man with regard to his spirit of discovery and inquiry and to speak of so-called atoms, no further divisible primitive atoms. For these primitive atoms must still contain matter, therefore occupy a space, and consequently be divi- sible. All we require is to discover the instrument and method, through which this divisibility may be effected. It is also very strange, that those who set forth these primi- tive atoms, give their apodictical opinions upon things they do not know, for none of them ever saw or ob- served these corpuscles, they are quite an arbitrary supposition, and physicians and natural philosophers who are constantly talking of a precise science, have in this been very inexact. They should not be so, because physics and chemistry furnish so many proofs of the daily increasing divisibility of matter. 244 One grain of beaten gold can be divided into four million parts. The 2,500,000,000th dilution of arsenious acid, and of the arseniate of ammonia, can be recog nized by means of the appropriate reagent. According to POPPE, the 240th part of a drachm of carmine dyes 60 lbs. of water, through and through. One millionth part of the 60 lbs.-one drop-put on a piece of white paper, and again divided into a million parts, does still allow each particle to be recognized by its colour under the microscope. One grain of copper dyes 10,557 cubic inches of water blue, and can, in this manner, be divided into 22,738,600 visible parts. Less than even one grain of cochineal, dissolved in liquid po- tassia, imparts a purple colour to four gallons of water; in this instance, the substance must have been at least 10,000,000 times diluted, and notwithstanding this, each drop can contain again as many particles, which are visible to the eye. Water which contains the 450,000th part of iodine, takes a plainly visible blue colour, if some starch is put into it. If a piece of ivory or white satin is dipped into a solution of nitro-muriate of gold, and afterwards thrown into a vessel containing hydro- gen gas, it becomes covered with a film of gold, which in thickness hardly exceeds the ten millionth part of an inch. Platina can be made into a thread, which is equal in thickness to the 30,000th part of an inch. One cubic inch of water yields 1,728 cubic inches of steam, and what power does this not exert. The thin- nest part of a soap-bubble equals in thickness the 2,500,000th part of an inch. Dr. BUCHHEIM, in Dorpat, found that tartrate of strychnine tasted bitter in the 48,000th, tartrate of quinine in the 10,000th, tartrate of chininium in the 4,000th, tartrate of 245 morphine in the 2,000th, and salocine in the 1,500th solution. THENARD also has recognized the 40,000th part of a grain of strychnine by its bitter taste; and according to THOMPSON, one grain of this alkaloid can be tasted in 80 quarts of water. One part of common table salt, dissolved in 1,640,000 parts of water, reacts still on nitrate of silver. Arsenic exists in exccedingly small quantities in the ferruginous waters, according to the analysis of WALCH- NER, and of French chemists. But it is distributed in minute particles throughout the water, so that it cannot be discovered in it, but only in the ochre which the water precipitates. Chemistry can hardly discover anything in many other mineral springs, which are reckoned' among the most curative ones, such as Wild- bad and Gastein. To explain their efficacy through the states of the temperature cannot be done, because other springs possess these also, without having a trace of the healing powers which appertain to the former. Here undoubtedly quite different potencies (which completely cscape all chemical re-agents) are at work. Chemistry is just as powerless in this instance as when inves- tigating the difference between magnetic iron and that which is not, and who would venture to deny the specific effects of the former? I know full well that of late it is attributed to a grouping around of molecules, by means of magnetism. But I also know, that no one ever saw or observed them; that this explanation is but an arbitrary one; that it does not even afford the shadow of an insight into the internal nature of the process, and I cannot participate in the opinion of many learned and unlearned prize-fighters, who fancy the riddle solved if they trauslate it from the 246 German into Greek or French, etc. But let us con- tinue with some examples of the great divisibility of matter. It is a well-known fact, that a single grain of musk has filled a large room with its scent during twenty years, and that notwithstanding this, no perceptible diminution could be found in the small quantity from which the scent had emanated. The musk had been divided into at least 320 quadrillion particles, which affect the mucous membrane of the nose, and, in susceptible persons, produce headache, fainting, and cramps. Less than a drachm of colour is required to impart colour to the leaves of a middling-size beech tree—a most beautiful green. The number of particles to which the drachm is reduced surpasses all idea. Here again you find the fact verified, that scents and colouring matter produce great effects in small quantities. But even greater and more wonderful effects are pro- duced by immaterial agencies, e. g., light, electricity, galvanism, etc. The immaterial agents of light, electricity, galva- nism, etc., produce still greater and more astonishing effects. Nitric ammoniuret of silver turns black when exposed to light; and I will explain the reason why this happens, because it plainly shows that in the other branches of natural philosophy there exists no hesita- tion to attribute the greatest effects to the smallest of causes. Now let us proceed to the explanation. A ray of light falls on the particles of matter, and causes them to vibrate quickly, and thence it arises that primitive bodies cannot remain any longer united in the same group in these particles. The elementary bodies of the one group cannot, therefore, be moved in unison 247 ' in the same direction. The result of this is another grouping, a combination or dissolution. I will here remind you of the wonderful doings of photography. A single drop of an employed acid to a hundred grammes is far more than sufficient to check the extraordinary quickness of light. The quickest human hand is not quick enough to regulate the thousandth part of a second's illumination on the most exact chemical layer, so that it was necessary to have recourse to mechanical expedients to fix the picture with the quickness of lightning. BERTSCH has fur nished, in his Collodium, a chemical composition, which enables him to pourtray, with the assistance of the solar microscope, each animalcula which constantly moves. about in a drop of water. TALBOT succeeded in giving, with the assistance of the momentary light of an elec- tric spark, a complete portrait of an English newspaper, which was fixed on a wheel, and moved round and round, and he did this in a shorter time than a minute. Galloping horses, driving carriages, and sailing ships, are faithfully represented as they move along. But all this happens only if one is able to calculate the hundredth part of a drop, and the intensity of light in its effects. The least mistake here, and the picture either appears changed or dimmed. Of great importance to photography are the different kinds of light. Thus, the prepared metal is not at all affected by the yellow light; the green light influences it but slightly; the orange light has a stronger influence; the red light a stronger, though still a very weak one; the blue light a powerful one; the violet light a more powerful; and the white light an almost destructive influence. These effects are de- termined by the alteration which the different lights 248 produce on the iodide silver and bromine which are used in photography, or by way of explanation, in con- sequence of another grouping, combination, or dissolu- tion of molecules, occasioned by light in these chemical combinations. How great are the effects, and in how short a time! And how vanishingly small is the quan- tity of the material agents! But all this occurs only if the relation between the acting parts are the proper ones ! Such is the case with Homœopathy, which exacts the right, the proper relations, and if these are complied with, then it produces the greatest results in the shortest possible time, with the smallest material doses, and this is also the reason why Homœopathy has stood the test in even the most acute cases. But if light and heat, electricity and pressure of air appear as conditions of matter, which, in a power- ful manner cause motion and thereby transportation of particles, there are, in hundreds of instances, lesser influences at work, notwithstanding they impart to matter the most wonderful movements. Wrought iron becomes crystalline and brittle by a mere shock; the lead-containing tin of the organ pipes assumes, in con- sequence of the sound causing vibration, a crystalline tissue. MORICHINI, in Rome, caused iron to become magnetic by exposing it to the rays of violet light. Minerals with smooth polished surfaces, such as lime, spar, quartz, arragonite (mica), become electric by pressure and heat. Most interesting also is the catalytic process, where a body, merely through its presence in another, is said, by transferring to it the movement of its molecules, to occasion dissolution, and a grouping of molecules into entirely new bodies without connecting itself with the L 249 So same, or losing any of its particles or peculiarities. does diastase, even in an impure state, possess the pro- perty of changing amilon, in such a degree that in a solution containing part of it, 2,000 particles of starch are changed to a certainty into gum and 1,000 into sugar. In the same manner does sugar, on coming into contact with a trifling quantity of sulphuric acid change into grape sugar; it is also observed that the elementary parts of amilon, and those of water, take a new form without the sulphuric acid, which had been the cause of this alteration, losing its chemical character. It remains, with respect to other substances which it affects, just as active as ever, and as if it had affected the amilon in no way whatever. Facts, like these, should remove the doubts of chemists respecting the efficacy of the small doses of the homœopaths. Next to these, come some facts out of vegetable life. In it the albuminous bodies play the chief parts. Without them, the highest organized working tools (Werkzeuge) of plants cannot be of duration, nor perform any vital function. Hence they are particularly liberally repre- sented in the points of roots (wurzel-spitzen), in the buds of leaves and blossom, in the pollen grains, in the embryo bag of the ovum, in the seed, parts which are distinguished by an active change of matter. It is these, which merely by their presence change cellular substance, amilon, woody substance and fruit-marrow into dextrine, consequently from insoluble into soluble bodies, and thereby create them for the nourishment of plants. And these albuminous bodies, which determine the change of matter, exist, proportionally speaking, only in very trifling quantities, whereas, the amilon-like bodies form by far the greater part of the plant. But the former, by their properties (pecu- 250 liarities), are equally important, nay, even more so than the latter, by their quantity. Here again, therefore, quality, even with the smallest material prevails, and quantity is not the most important, the most decisive. This is exactly the case in Homœopathy. Physiology also offers facts which prove the efficacy of small particles. Here SPALLANZANI's experiments are important. It results from them, that the spawn of frogs, in a certain degree of dilution, is more effective than in its primitive state. According to him, some tadpoles develop themselves from out a mixture of 22 pounds of water and three grains of spawn, and if the pound be reckoned at only 12 ounces, every drop of water contains but the 42.240th part of a grain of spawn. According to ARNOLD's experiments, the 3rd centesimal dilution-one drop of which contains but the 1,000,000th part of a grain of spawn-has still the power of impreg- nating. The 1,000th part of a grain of strychnia caused tetanus in frogs, which lasted for hours. In a frog, which the day previous had been tetanic for some hours by the 10,000th part of a grain, but had recovered, the 1,000,000th part of a grain caused a slight tetanus, which, after several hours, terminated in death. On making the second experiment, the nervous irrita- bility against the cause had evidently increased, as often happens in other diseases, where the sensitiveness to that which caused the disease whether a drug or anything else, sometimes lasts a long while. Thus, the smell of food, which caused a gastric fever, is sufficient to produce. immediate vomiting, nay, even a recurrence of the fever, whereas other smells are productive of no evil effects. This susceptibility of the body to certain irritants 251 surpasses all other chemical re-agents; shows itself in particular in those persons who, in consequence of diseases from taking medicines, or who, from the with- drawal of stimulating influences, are in a state of in- creased excitability. CASPAR HAUSER, and the experi- ments which Professor DAUMER and Dr. PREU made on him in Nuremberg, give a striking illustration of this. Many medicines in the 30th dilution had so powerful an effect upon him, that smelling alone at a phial con- taining one globule medicated with the aforesaid potency, produced in him a not unimportant number of symptoms, which, for the greater part had been observed in expe- riments made with stronger doses on healthy persons. In the same manner, Dr. FRÖHLICH, in Vienna, expe- rienced the most striking effects of aconite in the highest dilution, and many other physicians relate alike of Natrum Muriaticum in the 30th dilution; which is the more extraordinary, as they daily partake of large quantities of salt in their food, without feeling any effect, a proof that by the mode of preparing drugs as re- presented by Homœopathy, many of the remedial powers of drugs are truly set free. Hereby bodies become best of all qualified, to impart their peculiar molecular move- ment to the organic parts, either catalytically or by entering into combination with the organic parts. It it is further considered, that the moveability of molecules is a characteristic sign of organic substances, that it keeps pace with the completion of organic forms, and may show itself in the most varying direction, as the one or other incitor causes dissolution and transformation by transferring its peculiar kind of motion, by which nearly indifferent bodies are changed into the very opposite ones, and vice versa, as I have proved to you 252 before to be the case with sugar and cyanogen; so it is evident, that only the peculiar kind of movement, therefore, the quality, with the smallest substantial vehicle, but not the quantity, is necessarily required, to produce in the organism the most varying, penetrating and lasting transformations. If we ask after the final How of these changes, we inquire after the internal process of life itself, for both fall together in one, and both are as yet hidden to the eye of the investigator. But this has not prevented us from proving the legitimate unde- niable truth and efficacy of the small, and even of the smallest, doses; and, from comparing them even with like illustrations in other branches of natural philosophy, and in particular those of chemistry, physics, and physio- logy, in which also effects are met with where only very minute quantities are taken into consideration, or where matter, from which the effects emanate, seems as such to be of no importance. I have here acted in accordance with the natural philosophers, who make it a rule to observe these phenomena in chemistry, physics, and physiology, even if their material vehicle were an exceedingly diminutive, or a large one, and to fix the laws that regulate them; who do not reject or deny, because scales cannot ascertain, or the senses not reach, the vehicle. For in truth it does not show any great penetration in natural philosophy to declare that which is imperceptible to the senses, to be nonsensical, and to pronounce mere ocular delusion a discernment of sound human intellect. For even more important reasons, that speak in favour of the analogies out of chemistry, physic, and physiology, plead for the small doses of homœopathy. 253 To adopt the latter, and pronounce the former im- possible, or incomprehensible, denotes no sound logic. Nor does it speak against the laws of gravitation, or of chemistry, that hundreds of investigators have never observed the course of the stars, or made chemical experiments; but just as little does it affect the efficacy of the small dose, if many physicians, without any practical inquiry into homœopathy, have peremptorily declared, that it was ridiculous, inefficient, and nought. It is no use to talk with such people; for they are upon a ground, which renders it impossible for them to recognize the objective laws of nature. This ground must be given up entirely, if they wish to be- come fit for instruction. You, however, who are pleased with both that which is great and small in nature, who with equal calm objective look observe and listen to the terrific storm, as well as to the most gentle working in the innermost cells of the organization, who find the ball of the sun equally comprehensible as the smallest sun- mote, and each equally efficient in its sphere—you, I am assured, have understood me. You hold with me, that the efficacy of the small dose has been proved, in so far as reasoning can prove it; that it is one of the most wonderful and blessed discoveries which has been made in the entire realm of natural philosophy, and more par- ticularly in medical science. 254 LETTER XVI. RESULTS OF HOMEOPATHIC PRACTICE. You are aware that since experiment replaced hypothe- sis, and a beginning was made to fix and observe the laws of phenomena, instead of hunting phantastically after the primitive cause (the goal hitherto and still shrouded in utter darkness) that physical sciences, and in particular, chemistry, physics, and astronomy, have ad- vanced more during the last seventy years than they ever did during the thousands of years before. Ho- mœopathy, pursuing the same track, has, during the last fifty years, done the same in materia medica and pa- thology, as well as in the true rational therapeutics, which originate out of these two, and has formed itself into a regular and extensive true science. But in the same man- ner (in which every tree is recognized by its fruit), so has it proved its inward truth, and natural legitimacy, in a brilliant manner, by its happy results in the treatment of disease. It has already extended its sphere of action over all the ailments of mankind, as well as those of animals; and this counter-experiment at the bed of the patient- this practical trial-has been so completely successful, that it can only create the greatest gratification, the no- blest satisfaction, and most fiery enthusiasm for its de- velopment and propagation. Although as yet in its 255 infancy, it is undoubtedly a Hercules in the cradle, des- tined to free one day (if constantly further developed), suffering humanity from its monsters of disease. Thus the scientific discovery of its principle, and the manner in which it is carried through, guarantees to us a rule which finds, and has found, its application to all diseased conditions. I repeat, to all diseased conditions, as, in the passion of combating, opponents have been bold enough to assert, that it is only fit for some, viz., chronic cases, but that it is entirely ineffective in acute diseases. This objection is quite unfounded, like all the others, for the daily experience of many homoeopathic physicians, as well as the tables drawn up from the reports of many years' hospital and dispensary practice, prove the falsehood of the afore-mentioned assertion in a striking manner. These statistics are published in ROSENBERG'S work, “Progress and Results of Homœopathic Practice,” in the different homoeopathic journals of RUMMELL, GRIESSELICH, MÜLLER and MEYER, HIRSCHEL, WURMB, etc., and every one who cares about objective truth, will find in them the vouchers. To communicate, or give only an extract of them, would lead me further than time and space will allow; I therefore request you will examine them yourself in the afore-mentioned journals. I direct your attention in particular to those of Dr. HENDERSON, Professor of Pathology, and Therapeutics, at the University in Edinburgh. I do this all the more as the proportion of cures and deaths remains equally favourable to homeopathy, notwithstanding this sharp critique and separation of cases. For under its treatment more were cured, and fewer died, than under 256 any other, a proof that it need not fear any criticism, and that it appears always in a more brilliant light the more scientifically it is tried, both in theoretical and practical respects. All the points which the more recent scientific statistics require, have been considered by Dr. HENDERSON, such as the subjective contem- plation of the observer, the real significance of the names of diseases, the kind of life which patients have led, their nutrition and state (of health) before illness, their age, the attendance, food, the encourage- ment, the size of the hospital (as in the larger mortality is greater than in the smaller ones), the virulence of epidemics. Dr. KLOTAR MÜLLER has, in the fifth annual, No. 2 of the Homœopathic Quarterly Journal, furnished us with a first rate work of the same kind respecting the cases of intermittent fever treated in the Leipzig Homœopathic Dispensary during the year 1853, an essay replete with professional knowledge and dignified perspicuity. He rebuffs in the same with just indigna- tion those gentlemen who, in their so-called rational impartiality, claim diagnostic skill and credibility as their sole privilege. Annexed to this treatise are exact statistics of all the patients treated, during the year 1853, at the above Institution.* *The translator visited Leipzig on several occasions, and never failed to attend its Homoeopathic Dispensary. The friendly reception he met with from Drs. CLOTHAR MÜLLER and VEIT MEYER, will be always a pleasant recollection; and he gratefully acknowledges that he derived the highest instruction from his visits to that institution. He strongly recommends every medical student to visit it, as he will be certain to meet with high professional talent, and true affability. 257 These statistics will show you that Homœopathy has been applied most successfully in all possible kinds of acute and chronic diseases, such as inflammation of the brain, of the lungs, of the liver, of the kidneys, of the intestines, of the uterus, of the eyes, of the ears, of Dr. CLOTHAR MÜLLER generally uses his own Repertory, whilst Dr. VEIT MEYER'S favorite one is that of the late Dr. Pos- SART. Their manner of using these repertories, must con- vince every visitor that they have thoroughly studied them. The translator finds Dr. HEMPEL'S translation of POSSART a very imperfect one, and, on carefully comparing that gentleman's translation of HAHNEMANN's chronic diseases with the original German work, has noted his errors and omissions, and even re- translated most of them. To his surprise, these re-translations were not given to the public as his. In this case the "sic vos non vobis" of VIRGIL involuntarily recurs to memory. But Time and Truth, the great arbitrators, bring with them their own revenges. To return, however, with this passing observation, to Dr. HEM- PEL'S translation, the conclusion, after mature consideration is, that several persons must have meddled with it, as Dr. HEMPEL cannot have made those awful errors and mistakes, one of which is continually to translate the verb dröhnen (to vibrate) by the verb stöhnen (to groan). Some parts of chronic diseases are admirably rendered, and these, beyond doubt, are translated by Dr. HEMPEL himself (whom the translator will not judge as harshly as Dr. Carroll Dunham has done), whilst the errors and mistakes are evidently the work of others who were engaged in it, and whose great carelessness cannot be excused. Homœopathists, however eminent, must not be blind to their own faults. They should criticise for the love of science, and not for the satisfaction of personal rancour. Nay, when so many real enemies of Ho- mœopathy are to be combated, they should deal leniently with each other. Next to their own crowning motto of "similia similibus curentur," should be placed that of "l'union fait la force!" 258 the throat, of the larynx; against the sudden attacks of croup, and other acute diseases, which often terminate fa- tally in a few hours. If you compare the statistical results of the old and new school, you find that Homoeopathy may confidently enter the lists against its rival; for the rate of mortality, under its treatment is from 4 to 5 per cent., whereas, under that of Allopathy, it is at least 10 to 13 per cent. The treatment of cholera gave a striking proof of this superiority; and, through its successful treatment, Homopathy gained free admission into Austria. For, according to carefully drawn up statistics, which you can find also in the afore-quoted sources, the deaths amounted only to 8 per cent. under Homœopathic treatment,* whereas, under Allopathic treatment, they amounted to 51 per cent. and, even in the last epidemic, they were as high as 67 per cent., a truly horrifying per centage indeed. It should be mentioned that among these numerous cases, so favourable to Homœopathy, some were cured which had been treated in vain by several renowned Allopathic physicians, others which had been pronounced incurable, and many that had been so badly treated with the se- verest remedies and modes of cure that they were almost unapproachable by any natural mode of treatment. For, in how many instances, is the Homœopathic Phy- sician only then sent for, when bleeding, blistering, purging, and other violent remedies have already been resorted to. In such instances, three enemies have to be combated: the disease, the medicinal effects, and the weakened vital power! And yet, how wonderfully * Dr. STENS says, in a communication to the translator, that these data are reliable ones, and that they cannot be overthrown by the mere assertions of Dr. DUDGEON. 1 259 quickly does the homœopathic treatment even then suc- ceed in many cases! I myself was called in to see a child, one year old, suffering from inflammation of the lungs, which had been treated by the Allopathic Physicians with the entire anti-phlogistic resources, and more in particular, with Tartarised Antimony. Hepatisation extended almost completely through both lungs, so that a small part of them only was fit for respiration, and that most painfully, with the head bent backwards. The features bore already the impress of death, the beats of the pulse could no longer be counted, and during the last 36 hours it had refused the breast. The physicians who had attended upon it repeatedly told the father that his child was lost. It was about six in the evening, and I at once gave some globules of Aconite, 30 dilution, and an hour afterwards, a few globules of Acidum Nitri, 30. After the second dose, the child slept quietly for some hours; towards midnight it again took the mother's breast, and then fell quietly asleep. The recovery progressed in so quick a manner, that the child was completely cured in five days; and what do you think that the Allopathic colleague (who had witnessed this wonderfully quick re- covery of the child he had given up) did when he was told by the child's father that a change for the better had taken place? He, in harsh language, asked him how he could believe in such nonsense; to which the happy father replied that he would rather believe in it and see his child saved, than be obliged to cover it with a few shovels of earth, in spite of all his noisy and much-praised learning. Enraged at this, the colleague rushed out of the house, and until the present hour the idea has not struck him of inquiring into Homeopathy. Assuredly, if truth were to fall from Heaven into the very 260 So re- lap of these gentlemen, they again would shake it from them, and, if possible, drown it in the depths of the sea. luctant are they to admit the truth. Dr. WILDE, of Dublin, a man of considerable talent, says very impartially, when speaking of the Homœo- pathic treatment of acute diseases: "Whatever the opponents of this system may please to say, I feel bound to declare-and I am not an Homœopathist-that the cases which I saw under treatment in the Homœopathic IIospital in Vienna, were equally virulent and acute, as those which I had an opportunity to observe anywhere else, and that the statistics prove that the mor- tality in it is far less than in the other medical hospi- tals in Vienna. The Austrian Proto-medicus KNOLZ has published the Statistical Reports for 1838, which record only a mortality from 5 to 6 per cent. under Homœopathic treatment, whereas that in the three other hospitals gives a mortality of from 8 to 10 per cent. These statistics have been continued up to the year 1852, and the same successful result in favour of Homœopathy has remained throughout the most differing epidemics." The literature of Homœopathy abundantly furnishes also, in its practical results, the proof, that it is a peculiar bright side of this method to suppress severe diseases, even in their very commencement, inasmuch as it indicates to the learned in the physiological mate- ria medica, without further loss of time, the specific remedy, which, by its direct relation to the disease, causes, in a direct manner, the curative efforts to operate Thus it frequently succeeds in preventing the further development of inflammation of the brain, of the lungs, and curing them in a quiet, quick, and perfect It is truc, that all the noisy paraphernalia at once. mauner. 261 of the other methods are dispensed with, which furnish ample reason to admire the knowledge as well as the zeal of the attending physician, but which allow the disease to reach its dangerous height, whence it either terminates in death, or in a wearisome convales- cence; but there is no doubt on whose side true curative art and glory are to be found; as it is a fact, long re- cognised, that successful preventions are better than the best of remedies. In a similar manner, the Homœopathic prophylactic treatment has proved very efficient in many epide- mics, such as in those of scarlet fever, measles, and cholera; inasmuch as remedies which produce in healthy persons a state quite alike to that of the epidemic, when taken in small doses, remove the susceptibility to its influence, protecting in the same manner as cowpox against smallpox. Nor is the quick recovery under Homœopathic treatment to be lost sight of; for under it patients are neither weakened by bleeding and blister- ing, nor by severe purgatives and vomiting. Recovery is also not interrupted by the after-effects appertain- ing to so many drugs. Of especial importance is this to the poor, who need their time so necessarily to find themselves in food. The reformer must therefore not lose sight of this saving in time; if the social question, the most important problem of our time, is to be solved completely. I also call your attention to the fact, that this treatment renders many painful opera- tions superfluous, inasmuch as it removes malignant tumours, ulcers, and polypus, merely by the administration of the smallest internal remedies. Hereby it solves one. of the most beautiful problems of the physician, viz., to do away with operations, by rendering them unnecessary. 1 262 A brilliant proof of this is the recovery of the Field- marshal Count RADETZKY from medullary sarcoma of the eye, which having been recognised as such by Pro- fessor JAEGER of Vienna, and Professor Dr. FLANER in Pavia, had through this very diagnosis been declared incurable, as the soft cancer in general is looked upon as unapproachable by every radical treatment. The Actæ (vouchers) are kept in the Imperial Record-office in Vienna (the case itself is described in a monograph), where you can read it in all its details; I only will quote to you the letter which the Count addressed to the Vienna Zeitung, after his recovery:- "I was some time back attacked by a complaint of the eye, which, last autumn, in consequence of great corporal exertion, increased suddenly to such an extent, that I not only saw myself threatened with the loss of the right eye, but also, from the character which the disease seemed to assume, saw that my life was thereby endangered. This was, at all events, the opinion of the very clever and experienced oculist physicians (Professors Dr. JAEGER and Dr. FLANER). Under these danger-threatening circumstances, I en- trusted myself to the sole treatment of my Homœopathic physician, the Imperial Royal Counsellor and directing Physician of Brigade, Dr. HARTUNG; and his experience and science succeeded, in a comparatively short time, to deliver me from my already far advanced complaint. I must leave it to the faculty to value the scientific treat- ment, pursued in this instance, but cannot possibly rest satisfied with mere thanks. I wish that the world may know what deep gratitude binds me to the man, to whom I am indebted for the preservation both of my sight and life. For this reason I request the Vienna Zeitung to 263 open its columns to these lines. May science by this (no doubt rare instance) be enriched by a precious expe- rience the more; if so I will be thankfully reconciled and consider my sufferings a wise dispensation of Provi- dence." "Mailand, "12 Mai, 1841." "Count RADETZKY, Fieldmarshal." That the medicines, on account of their tastelessness, cause no sickening feeling, and can therefore be easily administered to every patient, is a circumstance which strongly recommends Homœopathy, in particular in the treatment of children. Children do not alone take the medicines without any reluctancy, but they even ask for them; and it is certain that through this circumstance alone, thousands are cured of most painful diseases, and saved the most tormenting deaths. Loving parents feel this full well, and cannot sufficiently express their gratitude. All unprejudiced physicians have moreover recognised the fact that Homoeopathy renders the great number of medicinal diseases impossible, and does cure them when already existing. The bulky administration of drugs weakens and destroys both mind and body. Under Homœopathy, neither mercurial, iodine, china disease, nor valeriana and chamomilla rheumatisms can occur, which already now are enumerated in Therapeutics, and are justly considered as ailments of humanity very diffi- cult to be cured. It does not possess those victims of original and medicinal diseases, those walking proofs of medical infatuation, which, a disgrace to science, crawl around the mineral springs and water- ing places, and scoff at science. With Homoeopathy, patients do not run the danger of getting the skin and 264 face died black, as often occurred through large and repeated doses of argentum nitricum. Professor ALBERS relates a charming story of the kind in his recently published Materia Medica. This many practitioners of the old school may find very interesting; but the poor patients do not know where to hide their faces nor what transformations may yet be in store for them. I am now going to mention to you a very great ad- vantage of the new method, from which the poorer class of people especially derive great benefit, viz., its cheap- ness.* This advantage is a double one; for they have no outlay for medicines; and being, therefore, no longer in fear of incurring these expenses, they apply all the sooner for help, and are, as a matter of course, frequently the sooner cured. Through this, they gain time, which they may be able to turn to a profitable account, and so be able to provide for their families. How many parents. have not applied for help until too late, when the disease had become incurable, and that because they either could not pay the apothecary or obtain the medicines on credit? How many a father, mother, or son died in the prime of life for this very reason, and left weeping or- phans and old parents to the charge of the parish autho- rities? Yes; if you visited with me the poor man's cabin, you would find my assertion not exaggerated, that millions of fellow-beings thus fall a prey to misery, and that, in this manner, by one blow as it were, Government * Dr. STENS speaks here of Prussia, where physicians are obliged to give the medicine gratis, as Government, to protect the Allo- pathic apothecaries, does not permit them to make extra charges on this account; the physician's fee varying from oue shilling to one and sixpence, includes medicines also. 265 is robbed of millions of able-bodied persons, and that mil- lions of helpless beings are left to the charge of the parishes, so that a double loss results, viz., an active and a passive one. Is this source of misery never to be done away with? Does not the welfare of humanity exact that this should be done quickly? And does not Homœopathy offer the fittest means? If, moreover, you consider that the medicine accounts for armies, hospitals, etc., swallow thousands of thalers, which might be spent in giving better attendance, as well as in erecting many desirable institutions; and now, if with an outlay of one hundred thalers (£15), a hospital like the Charité in Berlin could be supplied with medicines for a couple of years, you will, no doubt, recognise with me the im- portance of this state of affairs, and consider it a duty to recommend this matter most earnestly to the kind con- sideration of all those men whose duty it is to solve this social question in our present highly important times, and more especially to the Ministers of Finance. I will now give you a few details respecting the Bill of Costs. In the year 1840, the maintenance of a patient cost 3 Sgr. per day to the Homœopathic Dispensary in Leipzig; in the same year, the general director of the Charité Hospital in Berlin calculated that each patient cost them 7 Sgr.; thus, the expenses of each patient amount to 33 Sgr. more in the Charité than in the Homœopathic Dispensary. If it is taken into consider- ation, that the Directors of the Charité provide an- nually for 10,000 patients, and that each patient re- mains on an average 20 days in the hospital, it will be found that the expenses amount to 62,500 thalers 131 Sgr., Prussian currency. In a Homœopathic hos- pital, the treatment of the same number of patients, on 266 the same conditions, would only amount to 30,555 thalers 13 Sgr. The Charité would, therefore, save 31,945 thalers by adopting the treatment prescribed by the Homœopathists. From a similar calculation it results, that 150,000 thalers would be saved, if an army of 30,000 soldiers were treated homœopathically. In page 316 of KNOLZ's statements respecting the hu mane institutions and hospitalsof Vienna, published anno 1840, we find (1) that 20,545 patients were treated in the I. R. General Hospital, during the year 1838; and, on page 214, that the general expenditure of this Hos- pital amounted to 280,222 florins (those of the lying-in ward and that of the lunatics are not included). The outlay for medicines alone amounted to 36,642 florins, according to the Austrian poor-taxes (S. I. c. f. 213), so that a single patient costs 13 florins 38 krs. to the General Infirmary; and, if we calculate that every pa- tient remains on an average 20 days in the hospital, the expenses per diem for every patient would amount to 41 krs. (2)-731 patients were treated in the Hospital of the Elisabethinerinen in Vienna, auno 1838. The hospital expenditure amounted during that year to 12,893 florins 533 krs. (KNOLZ, f. 230); consequently, in this hospital every patient costs on an average 17 florins 361 krs.; and the above proportion kept by each patient costs a day 52 krs. (3)—3,609 patients were nursed in the year 1838 in the Institute of the Charitable Brothers in Vienna. The total expenditure in this hos- pital, according to KNOLz, f. 237, amounted to 37,490 florins. Each patient, therefore, costs 10 florins 23 krs. or 311 krs. per day. If we contrast the expenditure of the Homœopathic hospital, in Vienna, with it, we find that, anno 1838, 604 patients were treated in its wards, 267 and that 4000 out-door patients received medicines be- sides, and that the ENTIRE outlay of the hospital, accord- ing to KNOLZ, page 248, amounted to 4,548 florins. The medicinal outlay for the 4000 out-door patients in- cluded, each patient cost the Homœopathic hospital of the Sisters of Charity 7 florins 31 krs. and, retaining the same proportion as before, each patient costs them 221 krs. per diem. 24,885 patients were treated, anno 1838, in the three Allopathic hospitals in Vienna, and the total expenditure, medicines, etc., etc., included, amounted to 330,405 florins. According to the above calculation, every patient costs 13 fls. 19 krs. on an ave- rage, and the daily outlay for each patient amounted to 40 krs., therefore, 171 krs. more than in the Homœo- pathic hospitals. The difference between the cost of a pa- tient treated allopathically and one treated according to the homœopathic system amounts, in this town, to 17 krs. per day. If we take the same number of patients, and allow the same time of treatment, the total amount of expenditure would be, according to the homœopathic rate, 187,156 fls. 7 krs., and Government would, therefore, save 143,248 fls. 53 krs. in these three Vienna hospitals alone every year, if homoeopathic treatment were adopted in them. You see what enormous savings the Austrian Government, and, under similar circumstances, every other Government, would make, without its sub- jects suffering in the least thereby, if, in all civil and military hospitals, the homœopathic treatment were to be adopted, assuredly, an object of the highest importance, and well deserving to be considered by all parishes in all towns and states, as well as by the Ministers of Finance, etc. These are indirect taxes, which exceed the direct ones often by far, and Government is the more bound to free its 268 citizens from them, as, at the same time, by so doing, it strengthens itself. It is evident, that if Homœopathy possessed only the advantage of cheapness, this would be no sufficient ground for this reduction of expenditure, as the life of man is of higher value than gold. It is evident, from the rate of mortality, viz., that of 4 to 6 per cent. under homœopathic, and 10 to 13 per cent. under allo- pathic treatment, that the former saves 6 to 7 patients out of every hundred more than Allopathy. Homeopathy does therefore, not merely save large sums of money to Govern- ment, but also a great many lives, so that it is strengthened in a twofold manner by it. If you add to the favourable mortality and the cheap- ness of this method, the mildness of its application, in which all the tortures of the old school, produced by bleeding, cupping, blistering, cauterising, etc., etc., are banished, then there can be no doubt, but that things must soon turn in favor of Homœopathy, if the above advan- tages are considered in a calm and unprejudiced manner. It is here also the proper moment to mention the favour- able manner in which this method has already in- fluenced the veterinary treatment; the more so, as a healthy stock of cattle is of the highest importance, not only for the individual owner, whose entire existence often depends upon it, but also to the whole country; for which reason national agriculture ought to take a par- ticular interest in it. Repeated experiment has shown that Homœopathy has proved curative, not only in the more common diseases of animals, but especially in those which, until now, were considered incurable, such as, anthrax in horned cattle, glanders, tonic spasms, monthly blindness, and disease of the glands of horses, the sturdy (giddiness of sheep), etc. All these frightful 269 diseases, these until now truly unconquerable demons of agricultural welfare, which frequently ravage entire flocks, and reduce the most well-to-do farmer to beggary in a few weeks without his fault, were successfully combated by Homœopathy. Hereby the excellence of this method wasin- contestably proved, as there can be no question of faith or de- ception in animals. Allow me to mention a few instances. in favour of the above. Mr. VON OHEIMB, first lieutenant in the Prussian army, says :-"In the month of Sept. 1833, all the cattle on my farm, Neudorf near Nimptsch, Silesia, were seized with the flaps and foot-rot. To obtain a very decided proof of the efficacy of Homœo- pathy, I allowed one ox and four cows to be treated by a clever Allopathic veterinary doctor, who applied felt setons to them, strewed blue vitriol between their hoofs, and injected vinegar and honey into their mouths. This proceeding was carried out with the greatest care and trouble. Through this treatment, one cow became very lame, and remained so for several weeks, and the other had to suffer a great deal from the disease and the issues. The remainder of the flock, consisting of 40 animals, I treated strictly according to the homoeopathic system, and of these 40, only one draught ox became seriously ill, and the others only slightly so; they also had a quicker re- covery than the former ones (ZoOVIASZ, i, 2, 109). The same gentleman and the chief Veterinary, DR. SCHMAGER have cured several cases of monthly blindness; and the Veterinary Surgeons, SCHMAGER, GENZKE, and Lux, cured the disease of the glands, which carried off so many young horses. Equally successful were these gentle- men and some farmers ia curing the glanders, where the Allopathic Veterinary Surgeons advised that the horse so attacked, at once should be killed; the same with cascs 270 of tonic spasms of horses, which, in the Royal Veterinary School in Berlin, is declared to be an incurable complaint; the advice there given is to kill the horse at once, to save him the torture of dying from starvation. I once heard a Professor, lecturing on anthrax, exclaim, in a very emphatic manner, "Gentlemen, the only remedy is the club!" Here, again, you are told to kill. Well; for my part, I wish from the very bottom of my heart that the weightiest club of science and experience may soon be raised to crush and annihilate for ever this disconsolate and fatal doctrine, instead of killing these poor sick ani- mals, these precious jewels of agriculture, which Homœo- pathy can free from these complaints. Of the cure of the anthrax I last year and the year before witnessed here in the neighbourhood some brilliant cases. A far- mer saved 10 cows which had been seized with anthrax (and had been given up) by administering a few drops of the fourth dilution of arsenicum to them. Mr. RHODE, the Veterinary Surgeon of this place, cured a horse, suffering from a disease of the bones, which had been treated ineffectually with all kinds of allopathic remedies, with a few drops of the ninth dilution of silica. Professor Dr. PRINZ, president of the Veterinary School in Dresden, has, in most instances, declared him- self in favour of the homeopathic treatment. Many, and those the most successful Veterinary Surgeons of the Royal Saxon Cavalry, treat sick horses according to the homœopathic principle. A great many farmers in Thüringen and Saxony do the same. A vast number of animals-cows, pigs, horses, and sheep-have been cured by my respected and much distinguished colleagues, Dr. BÖNNINGIIAUSEN, in Münster, and Dr. GAUWERKY, in Socst. Their cures amount to thousands. Dr. GAU- 271 5 WERKY has classified them in the regular form (Statisti- cal Report) and forwarded them to the Home Office for examination and consideration. In Vol. I., Number 2, 1854 of the Revue Medicale Homœopathique d'Avignon we find very interesting communications respecting the investigations made in St. Christol by Dr. DESTREUX, with regard to the epidemic flaps and foot-rot disease of cattle. I call your attention especially to the statistical part. Under the expectative method (doing nothing), the duration of disease was on an average 123 days; under homœopathic treatment, 73, under allopathic treatment, far beyond 121, so that the methods rank with animals in quite the same manner as with man. Most success- ful is the homœopathic treatment; next, the expectative one; and most unfavourable, therefore, last of all comes the allopathic practice. During these observations, the great usefulness of the homoeopathic prophylactic treat- ment manifested itself. For, of the 11 cows treated in this manner, only 3 were attacked, two on the first day after having been placed apart, and one on the second day. Their illness lasted on an average only 51 days. And what is your opinion after all this? Can it not be asserted, with perfect justice, that Homœopathy has spread the sphere of its activity with brilliant result over all existing ailments both of man and animals, and that it has met with a practical realisation which leaves all other modes of treat- ment far behind! How many benefits may it yet have in store for suffering humanity and ailing animals, benefits which will only become apparent when it is more fully developed? And, should this not spur every one on to exert himself, in spite of all obstacles, for its further propagation and recognition? Yes, here, where the happiness of millions, and again millions, is at 272 stake, the self-interest of a few must be silent, and truth which has risen clear and brilliant as the sun out of this fire-bath of facts, will and shall be in future the sole lead- ing star on which the rulers of nations and the benefactors of the human race will cast their eyes. # 273 LETTER XVII. HISTORY OF HOMEOPATHY-HAHNE- MANN'S LIFE AND LABOURS. It is to Hahnemann's indefatigable zeal, inquiring mind, and great powers of observation, that we are indebted for his great and wonderful discoveries-discoveries, the advantages of which are incalculable, in so far as the welfare of humanity is concerned. Through these disco- veries entirely new facts were revealed, and the change of many old arrangements and views became necessary. Every great truth has always met with severe opposi- tion; in fact, the greater the truth, the greater the opposition. So it here happened over again, and those who undertook to carry the god-like spark into the obscure regions of human knowledge, met with a similar fate to that of those who ventured on a like task before them; or, to speak with MOSTHOFF, there was a repetition of Prometheus's fable, viz., the battle of man against civilization, which, like a tragical characteristic, runs through the history of the world. Firmly convinced of the justice and truth of his doctrine, the daring T 274 founder of Homœopathy could not be deterred from thinking, working, and battling for the noblest interests of humanity, and from devoting all his energies, time, and life to this important task. He knew the world too well not to be aware that his doctrine, like every new discovery or invention, would cause all the passions and self-interests to rise against it, and that LICHTENBERG'S equally witty and true re- mark would hold good, viz., "PYTHAGORAS, on discover- ing the problem which bears his name, offered a heca- tomb to the gods; since then, all oxen roar when they hear that a new invention has been made." Tumul- tuous roaring indeed has taken place, and the passionate. opponents resemble Baco's night owls, which only see in the obscurity of their reveries, but become blinded by the light of experience, and see that least of all which is easiest to be seen. Instead of investigating Homœopathy, it was abused; instead of experimenting, the reigning school sought, in its so-called rationality, the standard by which Hahnemann's doctrine might be examined and judged. To this he justly objected, for he could not sanction mere theoretical arguments against a knowledge which was based on experience. Knowingly or un- knowingly, they confounded the DISCOVERIES with their SUBJECTIVE EXPLANATIONS, and adhered to the LATTER, whereas only the FIRST ones could and should be the objects of practical examination and criticism. A PECULIAR CHIMERA of Homœopathy was created, and this was attacked in a similar manner to that in which Don Quixote combated the wind-mills. Sanitary Councillor RÜMMEL describes this critique in a most striking manner : - "The manner in which Homeopathy has been criti- 275 cised is well known to the readers of these pages (the Archiv). In shallowness, one-sidedness, assumed im- portance, ridicule, and misrepresentation, opponents have tried to outdo each other. Merely glancing at the theory, they in silence passed over the numerous obser- vations which speak in favour of the new mode of treat- ment; they have dipped their fingers in mire and in bile to draw a caricature of Hahnemann's doctrine. And, not satisfied with prosecuting his doctrine, they slandered him and pointed out his peculiar foibles, in the hope of crushing the founder and his work at the same time. For this reason, I will give you a short biography of him. SAMUEL HAHNEMANN was born in Meissen (Saxony), on the 10th of April, 1755. After having attended for some time the two different schools of his native town, he, in the year 1775, went to the University of Leipsic, to study the higher sciences. From there he went to Vienna, and finally to Erlangen, where, on the 10th of August, 1779, he took his degree of M.D. He, after this settled down as a physician, in Hettstädt, in Mans- field. Soon after this he went to Dessau, where he filled up his leisure by studying chemistry, mineralogy, and mining. His researches in chemistry soon gained for him a European celebrity; with the illustrious LAVOISIER he was on intimate terms. As a practical physician, he also soon gained a considerable reputation in Germany, the uncertainty of this science, the unde- cided character of its resources, the uncertainty of their results; and, above all, the repeated injurious influence of the violent treatment generally in use caused him to practise no longer a science which, though it appeared of great value in so far as theory went, was, in reality, 276 hardly anything better than a coarse, empirical kind of routine, an irrational administration of drugs, the certain effects of which were equally unknown as the laws which should determine their choice. He therefore, gave up the practice of medicine, and occupied himself chiefly with chemistry, and the trans- lation of several medical works from English, French, and Italian, into German; in this manner, he supported himself and family during several years. You know how, already, in the year 1790, whilst translating the Materia Medica of Dr. Cullen, the effects of cinchona caused him to meditate and ponder over them, how then a flash of lightning fell on his mind, and caused the discovery of the Homœopathic principle, which made him resume the practice of medicine. But he worked with the greatest assiduity during six years before he published the least thing relating to the subject. It was only in the year 1796 that he com- municated his discoveries by letter to HUFELAND, and 10 more years clapsed ere he published the results of his experiments with regard to the effects of medicine on the healthy body, under the title, "Fragmenta de viribus medicamentorum positivis sive in corpore hu- mano sano obviis" (2 vols., 1805.) His writing the work in Latin furnishes ample proof that it was not Hahnemann's intention to create a sensation among the public. In 1806, followed a treatisc entitled "Art of curing based upon experience," and, in 1810, "The Organon of Medical Science," which ran through five editions, and was translated into French, English, Italian, Hungarian, Polish, Russian, Danish, Swedish, and Spanish. After this, the Materia Medica appeared, from 1811 to 277 1821, in six volumes, containing the effects produced by a great number of remedies in the healthy body. HAHNEMANN's last great work was that of "The Chronic Diseases, their peculiar nature, and homoeopathic treat- ment." The facts which all these works contain, as well as the truth of the principle, worked in a reformatory manner in all directions, and called forth an opposition which until now is without its parallel in the history of medicine. As everything proved abortive, the monopoly of chemists for the preparation of medicines was brought forward, and many Governments interfered in its defence. Tired of the constant persecution of his enemies, HAHNEMANN left Leipsic, where he taught his doctrine from 1811 to 1820, at the University, and went to Cöthen, where the Duke Ferdinand received him most kindly, and made him his Court Councillor and Physi- cian in Ordinary. Here he laboured until the year 1838. In consequence of his marriage with a Parisian lady, he went to Paris. Here, at last, his merits were fully acknowledged; his house became the meeting-place of learned and high-placed men, and his aid was sought after both by rich and poor. He thus, after a long life of labour, trouble, and persecution, passed the last seven years of his life in happiness. He died 1843 in the eighty-ninth year of his life, duly recognised and respected as one of the greatest bene- factors of the human race. In this manner worked and died HAHNEMANN. He was considered one of the most distinguished, learned, intellectual, and successful practitioners, up to the moment that he introduced a change into the practice 278 of medicine, but as soon as he attacked the old school of medicine, the majority of physicians considered him the very reverse of all this. But there were also clever and enlightened contemporaries who openly recognised his merits as a man and as a physician, and who did not hesitate to proclaim this publicly. Listen to what the great HUFELAND says:— "The subject (homoeopathy) becomes all the more important, as its founder is a man to whom we cannot refuse our respect. And that this is the case with HAHNEMANN nobody will be able to deny, and least of all the author of this essay, who has been attached to him for upwards of thirty years by the ties of friendship, and has always known and esteemed him as one of our most distinguished, intellectual, and original physicians." (Journal of Practical Medical Science, HUFELAND and OSSANN, 1826, part i, p. 7). In another place, the illustrious HUFELAND writes:- "The first thing which determined me to take public notice was because I thought it unjust to treat the new doctrine with ridicule and scorn. Add to this the respect which I had, from the very beginning, for its founder, and which I owed to his former writings, to the essential services which he rendered to medical science, a respect which I also had for the names of several respectable and unprejudiced persons, who recognised that there was real truth in the matter. I will only remind you of the President VON WOLFF, in Warschau, the medical councillor RAU, in Giessen, the medicinal Councillor WIDEMANN, in Münich. I afterwards had an opportunity of observing the successful administration of homoeopathic remedies, which, as a matter of course drew my attention to this subject, and must convince • 279 me that it would not do to thrust it contemptuously aside, but that it deserved a careful inquiry " (HUFELAND, Homœopathy, Berlin, 1831, p. 4). J. G. BERNSTEIN says: "S. HAHNEMANN, a much deserving physician, is known by his excellent prepar- ation of Mercury, viz. his Mercurius solubilis, his wine test, and, moreover by his chemical and pharmaceutical writings, and surgeons also owe thanks to him.” Dr. WEDEKIND, physician in ordinary to the Arch- Duke of Hesse Darmstadt, an opponent of homeopathy, says, notwithstanding this, when speaking of HAHNE- ΜΑΝΝ, "He is a physician distinguished by his learning and ingenuity, as well as by his literary pro- ductions." KOPP, in Hanan, says: "He who has impartially observed, and has critically followed HAHNEMANN's life, from his first appearance as an author, teacher, founder, and master of a new school, cannot deny the ingenuous spirit of inquiry, the specu- lative originality and mighty power of mind of the man. He, with great talent and sagacity, conjoins a knowledge of the human character with vast learning; he, with courage, tries to carry out his plans. Everywhere he betrays the experimenting observer, the former assiduous chemical student. Imperishable are assuredly his merits with regard to the individual particulars of the specific effects of drugs, and the degree of susceptibility of the human organism for them. It is a fact, that HAHNEMANN counts the most embittered enemies of homœopathy among those physicians who have neither studied nor practised it.” JEAN PAUL calls Hahnemann a singular double head of Philosophy and Learning, in his scattered leaves; and is of opinion that his system must finally draw after it 280 the ruin of the ordinary physicians. He says that as yet it is but little adopted, and that it is more abo- minated than inquired into. I might increase these opinions by many others, but these will prove sufficient for you, and I close Hahne- mann's Biography, therefore, with a faithful descrip- tion of himself, such as the Surgeon-General, Dr. GRIESSELICH, gave it in May, 1832. Every action of HAHNEMANN, though he is now about 77 years of age, shows the energy of a young man. The body would show no signs of old age, if white locks did not encircle. the temples, and if time had not, against his will, shaved his crown, though his baldness is hidden under a small smoking cap. Short and square, HAHNE- MANN is active and quick; every movement is life. The eyes indicate the inquirer, and out of them beams the fire of youth. The features are sharp and ani- mated. Age seems to be a stranger to the body, as well as to the mind. His speech is energetic, and often flows like a torrent of burning lava against the perse- cutors of those truths which he for years solicited humanity to inquire into. His memory is perfect, for he often, after long intervals, continues there where he has left off. If he becomes excited, which easily happens, friend, foe, or matters of science, are the cause of it. Then his words gush forth continually, his countenance becomes more than usually animated, and a peculiar expression settles thereon, which the traveller admires in silence. Perspiration covers the lofty brow, the little cap must be raised, and he has to wipe his head with his pocket handker- chief. The long pipe, his faithful daily companion has meanwhile become extinguished, and must be lit 281 afresh with the constantly burning wax taper; nor must the white beer (Weiss beer), a sort of table beer, be forgotten. The venerable old gentleman seems to have accustomed himself so much to this sweetish beverage, that a large tumbler full of it stands continually on his table. During dinner, HAHNEMANN also drinks this beer, which is unknown to the inhabitants of South Germany. He does not take wine; His mode of living is very simple, and patriarchal. That which happened to HAHNEMANN, occurred also to his disciples, who with love, perseverance, and self- sacrifice, studied his doctrine, and tried to propagate it, theoretically and practically. Eminent physicians grown old in practice, became converts to his doctrine, and sacrificed their lucrative situations to it.* They nobly persevered in the battle, which self-interest, vain desire for glory, obstinacy and self-interest continually caused them, and in which physicians, apothecaries, and governments, headed by the allo- pathic authorities, were equally active. The following physicians turned homeopaths. Drs. M. MÜLLER, after an allopathic practice of nearly twenty years' duration, Dr. SCHNIEBER, a former allopathic physician, Dr. FITZLER, who had practised allopathy during several years at Ilmenau, Dr. H. BETHMANN, an allopath of several years' standing, Dr. SCHWEIKERT, school and town physician in Grimma, after an allopathic practice of twenty years' duration. The Imperial Russian States Councillor KNIGHT, Dr. STEGEMANN, in Dorpat, the sanitary Councillor, Dr. RUMMEL, after an allopathic practice of ten years' duration, the Town and * The late Dr. FEWSTER ROBERT HORNER, formerly President of the Brit. Med. and Surgical Association, aud 27 years the Senior Physician of the Hull Infirmary, nobly followed this example.-Note of Translator. 282 Cathedral physician. Dr. MESSERSCHMIDT, Naumburg, who had been an allopathist during a number of years. Dr. GEORGE NECHER, in Naples, afterwards physician in ordinary of the Grand Duke of Toscana. The court physician, Dr. MUHLENBEIN, physician in ordinary to the Duke of Brunswick, and assessor of the Upper Sani- tary College of Brunswick, who had practised allopathy for upwards of thirty-three years. The medical Coun- cillor Dr. STAPF, an allopath of many years' standing, in Naumburg. Dr. G. A. WEBER, Court Councillor, and physician in ordinary to his princely highness the Prince of SOLMS-LICH and HOHENSOLMS. Dr. SCHULER, at Stolberg, on the Harz mountains, who had practised allopathy for twenty-five years, etc., etc. I might augment this number by many more; but those I have enume- rated will sufficiently prove to you that they are not young physicians who are enthusiastic for all that which is new, and as yet inexperienced and incapable of forming an opinion for themselves, who had become converts, but on the contrary, physicians, grown wiser by experience, who could full well compare the two methods and make a proper choice in accordance with their firm convictions. They all acknowledged the superiority of homoeopathy, and, to deny their demonstrative conclusive power, would give but a poor opinion of one's own judgment. These testimonials are contained in the different homo- opathic journals, in particular in the "Archiv," in the 'Hygea," and in the " Austrian Homœopathic Journal," where you may find them in great numbers, and they increase every day. But with these proofs of the efficiency and superiority of homoeopathy, the perse- cution and animosity of opponents keep a like pace, and the coarsest lies go hand in hand with the most bare- CC 283 faced impudence. Hear what the venerable Court Councillor, Dr. MUHLENBEIN, says upon this subject. "After having read the writings in favour of homoeopathy, and those that had appeared against it, I considered it my duty to talk the matter over with my special colleagues, and to call upon them to investigate it. Instead of adopting my proposal, I received scornful and declining answers; it was called downright non- sense, though these gentlemen had read but little on the subject, and had made no experiments whatever on patients. HAHNEMANN's mathematical denomination of medicinal doses so deranged their minds that they were unable to consider the matter in its proper light, nor comprehend what was really meant by it. They did all they could to turn homœopathy and myself into ridicule. The one maintained, that if homoeopathy were true, then present physiology was untrue. The other, that even if it were true, it still ought to be forbidden. The third said that he did very well with his allopathy, that it brought him money, and that on that account he would not give it up; the fourth wished to prove, by swallowing with impunity a dose of aconite (which he had by trickery obtained from one of my patients), that such doses could not effect anything at all; in another case the same individual made the attempt to create the real itch with sulphur; and not being able to effect this, he fancied that he had completely overthrown homeopathy, and so proved his utter ignorance of it, whilst the parties in whom sulphur had failed to produce this skin disease, looked wonderingly at him, and repeated his nonsense. Another gave a decoctum seminis cinæ, by table spoonful doses against hooping cough, and asserted that he had treated the disease homoeopathically, but 284 that he had not been able to cure it in that manner. Another acknowledged to me, in the presence of a patient, that he knew nothing of homoeopathy; he, in an underhand manner, took some powders away from one of my patients, ran with them to the club, and blowing them on the table, exclaimed, of what good can such trumpery stuff be to any one, and this he did say in the presence of a patient whom he had treated during sixteen years unsuccessfully for shortness of breath, and of which I had cured him through homœopathy. All possible means were tried to take patients from me; nay, even strangers who came to live here, and intended to take me for their doctor, were persuaded by all sorts of trickery from sending for me, that they might not be exposed to the poisonous treatment; these very persons, however, on perceiving their mistake, chose me, notwithstanding, for their medical attendant (Archiv. vi. 3, f. 57). This, with a few exceptions, is the true history of nearly all homoeopathic physicians. Dr. GASPARI, in Meseritz; Dr. SCHRÖTER, Medical Councillor; Dr. TRINKS, in Dresden; Dr. M. MÜLLER, in Leipsic; and Dr. STÜLER, in Berlin; were even treated worse. Medi- cal men exclaimed, to their own disgrace, as they did in the time of HARVEY, "Malo cum Galeno errare quam cum HARVAEO esse circulator." (In English : I will rather be wrong with Galen, than believe with HARVEY in the circulation of the blood, or of being a charlatan with HARVEY, as circulator, means as much charlatan, as one who believes in the circulation of the blood.") CLARUS declared openly, in the Medical Journal: "We have neither leisure nor inclination to study and investigate Homeopathy, but declare ourselves decided 285 opponents of the same.” Yes, the physicians and pro- fessors of the old school even boast of their ignorance of Homœopathy before their astonished listeners, and ask every student, if he has heard anything about this absurdity, and if some one or other with modest wil- lingness utters some casual phrase about this supposed quackery, see what a satisfied mephistophelic smile plays round the mouth of the-in his self-sufficiency-flattered professor! But take care, thou prophet on thy tripod, for its feet are rotten, during night it breaks down, and there, below, it does smoke awfully. Entire faculties see themselves forced to fulminate ex- communication against this doctrine, which overthrows all the great authorities of hypothesis. About a cen- tury and a half ago this was done in Edinburgh. Very striking is the example of Dr. GEORGE RAPP, professor of the medical faculty in Tübingen. In his essay, "Medical Clinics, and their relation to Practical Medi- cine, Tübingen, 1853," he says that the task of medical clinics consisted in giving to the student the necessary guidance and opportunity for treating patients, so as to turn his theoretical knowledge into practical account. The question: "Has the present Clinical Hospital done this?" He answers, "No." And he bases this denial on his own experience, and on that of others who attended it. He bases himself thereby on the fact, that the young physician, who enters boldly and courageously the road of practice, is soon obliged to admit, with the older colleagues, that there is a vast gulph between theory and practice; that he gradually loses his former respect for the academical authorities; and that it seems ridiculous to him, why, as practical physicians, we often seek to free ourselves from the 286 very dogmatism of which we were so proud in former days that we used to look down with utter contempt on our predecessors. Both scholars and schools prove to him the impossibility of making theories harmonise with what is required at the bed of the patient. Dr. RAPP maintains that a new real superstructure (Anbau) of Therapeutics has not been completed up to the present time. Experiment, observation, the instructive method have taken place in all the preparatory sciences of medicine, and given to it more or less superiority over minor practical medicine. The clinical therapeutical part had as yet not been treated as a physical science. Different physicians have repeatedly offered proposals for a self-dependent elaboration of Materia Medica, ac- cording to new and fixed principles. The half-com- menced attempts, however, were soon again abandoned. In times gone by, and even now, it is often sufficient to mention a clinical factum in a clinical hospital to bring it in contact with an ingeniously followed-up hypothesis, to introduce a dogma apparently new and rational in Therapeutics. He is right in believing, that we might have found out that now-a-days no preparatory science of the Clinical Hospital, by itself, could grant us a Materia Medica for the diseased organism. He considers it the duty of the clinical physician to investigate Homœopa- thy, and adds, that there are plenty of theoretical "rai- sonnements,” but not a single circumspect revisal and subsequent criticism by professors at the Universities. The daily increasing number of its followers alone would justify a critical inquiry into it. But, on account of the deference which the clinical physician owes in general to the practical medical public, and also on account of the intimate mutual scientific relation, he considers it 287 but just to become acquainted with Homœopathy. Or," asks he, " does the academical investigator stand so high-are the services which he has rendered to prac- tice so important-that he should feel ashamed of con- templating (examining) the performances of his practical colleagues?" To him the following words of VIRCHCW can be applied :-"The natural philosophic method demands ocular evidence, it excludes blind belief, granted authority, as well as obtruded confidence. It exacts inquiry, and he who has stood it becomes an authority. But if we, without any investigation, will recognize self-assumption for an authority, we cou- tradict ourselves, if we prosecute the schools. Fac- tions of schools can only be undone by emancipating the single ones, by allowing to them the right and means of self-determination, but not by forcing into one party, a single school, or a single flock.' RAPP considers, that according to these principles, his impartial examining clinical method is amply justified, and it were even desirable if, on the part of Govern- ment, regulations were issued for the comparative ex- amination of the different curative methods. It would be another question "Whether such an examination would appear advisable in the present position of the clinical physician, whether his scientific authority would not suffer thereby in the eyes of his colleagues?" The study of Homœopathy has given such unexpected results to Dr. RAPP, that he considers it his duty to continue inquir- ing into it, that he may obtain a firm foundation for a clinical practical medicine, fit for the present day, which he only sees in a thorough knowledge of the effects of drugs on the healthy and diseased organism. Dr. ARNOLD says, "I wish that the learned Dr. RAPP 288 would soon publish the result of his treatment, both as regards the number of cures and that of deaths, the time of duration, and the outlay for medicines. I have the firm conviction that the number will be equally satisfactory to financiers, as alarming to pharma- ceutical chemists; and that comparative statistics will soon convert all unprejudiced physicians to the new system. Further inimical prosecutions of RAPP, even if they should lead to his expulsion from the Clinical Hospital, would be no misfortune for his person, and not be able to put a stop to the onward course of science." And this expulsion has already occurred! In the spring of 1854, therefore, hardly a year after the publication of his book, Rapp was removed from his situation as clinical teacher, because he INCLINED TOWARDS HOMEOPATHY. And is not that which RAPP did the sacred duty of every clinical physi- cian? and does not every clinical teacher who omits to fulfil it render himself guilty of the greatest crime against science and suffering humanity? And what judgment will not be, after this, pronounced by the allopathic profession on the Homœopathists? RAPP'S removal is again one of those spring flowers which, by thousands, luxuriantly grow up out of the marshy grounds of hypothetical doctrines of so-called rational medicine; but, beware to approach too closely, for it has a very offensive smell. But truth can neither be the course of true science' annihilated thereby, nor can be checked. The following words of ANCILLON are valid: "The weak human arm cannot oppose in a lasting manner the laws of nature, nor overturn the regulations of the world. Man can accomplish a vast deal, if he moves on in the beaten track; but he will soon 289 be seized by the mighty wheel of time, carried away, and crushed, if he tries to force the spikes in a retrograde direction." And to these gentlemen we must repeat the words which Dr. WOLFG. MENZEL already addressed to them in the year 1830. "It is a disgrace to our age that Homœopathy meets with so many obstacles. It ought at all events to have been more thoroughly refuted, and quicker overthrown, or else been more thoroughly valued and propagated. The egoism of a few old medical choristers should, in our enlightened days, not rob a whole nation of the benefits that must result from such important discoveries.” Fully convinced of the truth of their doctrine, Homœopathists work actively on the fog of old prejudices disperses amidst the constant strife and contradictions that are going on; and the brilliant thought diffuses itself, spreading health and strength in every direction. In spite of the most severe opposition, Homœopathy has gained a firm footing in all parts of the civilized world. It has an abundant literature of several hundred works, in different languages, and above 2,000 physicians who openly proclaim themselves in fa- vour of it. Many of the principal towns in Europe do not count one but several Homoeopathic physicians, who have all more than enough to do. Vienna possesses 40 Homœopathic physicians; Paris, 50. In Germany, 6 medical journals are published, which occupy them- selves entirely with Homœopathy; in France, 5; in England, 2; in Italy, 1; in Spain, 3; North America, 2; The Brazils, 1. There are, at least, 18 learned societies for its further development. This number * This number exceeds 6,000 at present, whilst that of the mean pretenders, who silently and impotently aim at the practice of Ho- mœopathy sub rosa, cannot be enumerated.-Note of Translator. U Uor M 290 already existed in 1848. Since then, Homœopathy has vastly extended itself, especially in England and North America, and this proportion has, therefore, risen in a like degree. In the last three months, again, threc great associations of Homœopathic physicians have been formed-the one in München; the second in Madrid; and the third in Philadelphia. I must not forget to allude to the two professional chairs, which the Austrian Government has founded during the last year- the one in Vienna, to which a clinical hospital is attached; the other in Prague. Hereby Austria has, in fact, re- cognized the equality of Homœopathy with the old school of medicine. This is of all the greater import- ance, as Vienna has, for a long time, been the main fostering place of medicine. In latter timcs, Prague has rivalled it in this respect, in a most dignified manner. What is your opinion? Does such a history not speak in favour of the truth and inward value of Homœopathy? Does it not prove the falseness of the assertion of the opponents, that HAHNEMANN's doctrine is rapidly going down? Does it not teach us, in a strik- ing manner, that the power of facts is stronger than all the theoretical proofs; that it beats a path, through all obstacles? Does it not, as these proofs accumu- late, carry with it the guarantee of its final triumph, and general absolute recognition? Has not Homœopathy, pure experiment, and the observation of nature, instead of invented principles for its foundation? And does it not thereby stand to Allopathy in the same manner as every- thing which is fixed and determined, stands to that which is undecided, e.g., as astronomy stands to astrology; as che- mistry to alchymy? Docs it not rest thereby on the same unchangeable and indestructible fundamental pillars as 291 nature itself? Is it not, in the strongest philosophical sense of the word,a system of practical medicine; because it possesses a principle which has been derived from nature instead of being thrust upon it—a principle out of which all the different parts of the doctrine mutually penetrate, and animate each other, as one harmonious unity? Is it not a practical medicine, which from time immemorial has been the aim of all distinguished phy- sicians and benefactors of humanity? Has it not already, in the fifty and few years of its existence, passed through a brilliant history, to its own glorification? Yes, it has furnished already, theoretically and practically, the proof that it is of historical importance, that it ranks, according to its entire being and its incalculable consequences, among the greatest manifestations of our age, among the greatest and most benevolent discoveries which ever occurred. It has become a great and holy property of humanity, and we are firmly convinced that it will retain this property, under all circumstances; that it will allow it to develop itself in its natural and undiminished formation. The egoism of a few choristers, whether they belong to the antiquated, or to the more recent practice of medicine, shall not longer rob the nations of it. Therefore, cast a joyful look with me into the future, and join me in cheering those who are manfully struggling to propagate it. UorM LETTER XVIII. DETAILS AS TO HOW HOMEOPATHY IS COMBATED, AND REFUTATION OF THE OBJECTIONS ADDUCED AGAINST IT. In my last, I mentioned to you the severe opposition which Homœopathy experienced from its earliest infancy up to the present day. It herein shares the fate of every great truth, which unveiled entire new facts, and caused the transformation of deep-rooted opinions. All passions. were thereby roused up, and remain so still. Stupidity, malice, dishonesty, intentional blindness, arrogant ig- norance, foolish wrath, are alike busy in combating the new doctrine. Nay, the new-capped doctor of the old school, in whose ears still rings the last question of his examination, and whose first future patient is still in the enjoyment of perfect health, considers himself justified to look down with contempt on his elder Ho- mœopathic colleague, and to declare his mode of treat- ment a perfect absurdity. It is undoubtedly a great recommendation,' both to the student and examinandus, if he can relate a great many bad things about Homo- opathy, and if he foretells that its destruction is quite cer- tain, and will soon take place. I, myself, have witnessed this during the final examination. From the whole Mчou 293 manner of the opposition, however, it is clear, that the victory of TRUTH is little cared for, but well that of the FACTION. Therefore, all kinds of reasons and objections are brought forward, no matter whether true or false, as they are not valued according to their intrinsic merit but according to the EFFECT they may produce. For this very reason PERSONS are more attacked than the matter itself—the DISCOVERERS more than the DISCOVERIES—— the EXPLANATION of the law of nature; therefore, the subjective opinion which everybody can and must form for himself, more than the LAW OF NATURE, which is the expression of the objective truth in nature itself. When HAHNEMANN called out to his opponents— "Imitate; but do it faithfully and judiciously;" and appealed, therefore, alone to the decision of experience; they found it easier to prove in their study (whilst avoiding every actual experience), by so-called argu- ments of reason, the impossibility of Homœopathy, and they, therefore, met with the same fatality which HEGEL experienced, on demonstrating a priori, that there could not exist another planet between Mars and Jupiter; for, in the same year, the renowned astronomer PIAZZI discovered Ceres, which describes its course exactly there, where, according to HEGEL's description, no room existed for any other planet. And Homœopathy, which is said to be an impossibility, had the impudence to accomplish not only the cure of common diseases, but also to cure those which others considered IMPOSSIBLE to cure, notwithstanding the high-sounding, but empty phrases of its opponents. The shallowness of reviewers, who have just learnt sufficient of a subject to speak in an easy manner either in favour of or against an opinion; who make a deal of noise with empty words, and flowing 294 "Ex- orations also became apparent on this occasion. periment with candour, judge with impartiality," was not their Shiboleth; but rather want of fundamental- ness and surplus of dishonesty. HEINROTH called Ho- mœopathy a lie; F. A. SIMON called the Reformator in Cöthen, a pseudo-Messiah. From the pulpits of the University, this heresy is constantly excommunicated; and the younger generations are thus wilfully taught to abhor it; very few of them have read anything about it, and only know it by hearsay, or are incapable of con- sidering the matter in the light it ought to be looked at; they always bring their scales and measures, which are well adapted for their own inorganic Allopathy, replete with hy- potheses, but not for the objective organic truth of Homœo- pathy. Yea; it is a great triumph for this doctrine, and an indirect proof of its excellence, that it will not allow itself to be meted out with so rotten a measure; and, does it not, moreover, directly oppose the so-called ration- ality of the reigning school, by inscribing on its standard only those laws which have been ascertained by pure experi- ment, instead of those that are invented and embel- lished with all possible subjective opinions and suppositions. As a necessity, therefore, the standard for it is only to be found in faithful experiments, as well as in the candid and impartial comprehension of the results. For Ho- mœopathists desire, that medicine should be determined by nature, as a science-as a system-but not that nature should be determined by the system, as in Allopathy. The standard of the one method is, conse- quently, the very opposite one of the other; and each must, therefore be measured with its own, if both are to be properly estimated. HAHNEMANN, as a matter of course, protested against such objections, and his fol- 295 lowers did, and do so still, with the fullest right. He calls out to his reviewers: "If you will fare equally well, then imitate in a sensible manner! If you will not, then loiter on your disconsolate ways of blind custom in the midnight obscurity of dreamy systems, lured by the will o' the whisps of your celebrated authorities, who forsake you there where assistance is most needed." But of what use is it? Notions have so settled and fixed themselves in the heads of these authorities; a whole army of consequences has so attached itself to them, and has so grown together with their innermost being, that it is almost impossible for them to obtain a conviction of the incorrectness of their own ideas, much less of the correctness of others. Like bell-wethers, they are followed by the minor or lazy host of servile followers, who regulate their judgment not after their own opinion, but after that of others. Latterly, they have been joined by those who banish, from the very commencement, out of the circle of scientific investiga- tion, all that which cannot immediately be understood, even by the most ordinary mind, that which cannot be found by the microscope or stethoscope, by chemical re- agents, or that which cannot be dissected with the scalpel. An endless scepticism befalls these gentlemen; and they do not consider that others have the same right to doubt the correctness and admissibility of their misgivings. Thus we obtained a continued chain of sceptics, a true desert of Sahara, full of phantastical skeletons instead of lively and strong fleshy figures. CABANIS is undoubtedly right, in many instances, in maintaining that scepticism in medical science only promotes ignorance, and serves as a pillow for laziness. And, notwithstanding the means 296 are so close at hand wherewith they could solve their doubts, and arrive at correct conclusions, that are based upon facts. Why do they disdain to contemplate the repeated faithful experiments and unprejudiced observa- tions of nature? Very correctly, LA PLACE calls out to such: "We are as yet far from having recognized all the powers of nature in their different degrees of action, and it would be very unphilosophical to deny the existence of phenomena, merely because they appear unexplainable to us from the scientific height we actually occupy." And ABERCROMBIE characterized them as follows: "Whereas unlimited credulity belongs to weak minds, so does un- limited scepticism indicate a shrivelled-up mind, which bases its judgment upon incomplete data, and raises its own knowledge as a standard of truth." MostнOFF MOSTHOFF says, very appropriately," Beneficial, indeed, and neces- sary for the development of science, was the genius which constantly denies; but the fool who always denies is no genius for all that." L As everywhere else, so does also, in Homeopathy, the power of the accomplished fact decide, and such a one it is! Not by theories, sophistries, or proud contempt, does experience allow itself to be reasoned away. Of what avails the playing with ideas against the weighty seriousness of facts? Here is a ground capable of bearing; here are proper roots for the future of medical science, which the blight of ridicule cannot harm; here the foundation for a scientific edifice has been laid, against which even the heavy artillery of lies, of slan- der, deceit, deception, moral dangers, etc., proves power- less. As such an attempt to blight as it were (mehlt- haustückchen), Dr. HIRSCHEL quotes the remark of a medical charlatan, who warned his patients against Homœopathy, "because it caused people to turn green 297 inside and putrefy." I will now tell you a case which is here in its place, and which I experienced myself. A learned Allopath tried to frighten, from Homœo- pathy, a lady who was very particular about her skin, by telling her that all who were treated by it turned black. You can, after this, fancy the fright and disgust she had of such an infernal system. She suffered from a liver complaint; and had, as is often the case with such patients, many yellow spots on the face, and yellowish rings under the eyes. For several years, the sagacious disciple of ESCULAPIUS employed all sorts of remedies and modes of treatment; but, in spite of all this, the disease gradually gained ground, and the yellow colour threatened to supplant even the last spot of white. In the utmost despair, she proved faithless to her prophet, and surrendered herself to the infernal method-to black Homœopathy; and lo! after a few months, the monster of a liver affection, with its yellow spots and rings, was obliged to retire before the more powerful demon of Homœopathy; and her face, instead of assuming the threatened black, appeared in the purest white; and, as if they had changed parts, the Allopathical colleague, on seeing the result of the Homœopathic treatment, be- came jaundiced from spite, atrabilious, and malicious, and so he has remained to this day, in spite of the purest whitest light of the evident cure. But we may as well attempt to wash the negro white as to enlighten the wilfully blind. To waste only a moment in refuting such and similar aspersions, would be sinning against time. For opponents who, without trying something better, do not blush to doubt the gift of observation— the love of truth-yea, even the common sense of Ilomœopathists, have no right to expect any refutation. 298 With them no literary discussion can be carried on, for they openly deny all sense of honour and manners. Let them, however, consider the following words of Dr. KALLENBACH: "With what right do physicians of the so-called legitimate (allopathic) practice look down upon their Homœopathic colleagues with proud over-estima- tion of their position? Have not these made the same studies-passed the very same examinations which rational medicine exacts from its physicians? Do Ho- mœopathic physicians, therefore, not know quite as much as their arrogant opponents; nay, do they not understand even something more, namely, the Homœo- pathic mode of treatment, which the others hardly know by name? "Yea; and how often do they acknowledge this igno- rance by an ambiguous shrugging of the shoulders, when they ought to feel ashamed of doing so before better informed non-medical men? Or if afraid of com- mitting himself to a non-professional, how does then the much respected colleague-a real wolf in sheep's clothing—exclaim, whilst raising his shoulders with a pitiful air: Yes, Homœopathy will do well enough, but oh! the Homœopathists!' But, away from these futilities, if it could be of any avail to indulge in mockery and scorn, you know Allopathy would fur- nish us with plenty of material to do this to our heart's content. ( "I purposely communicated to you the contents and historical development of Homoeopathy beforehand, that it might be actually clear to you, how the wilful or un- intentional ignorance of these facts, is the origin of all prejudices, and even now proves one of the most important obstacles against its recognition and propagation. Some of 299 the prejudices and objections, such as the inefficiency of small doses, the insufficiency of the principle of Ho- mœopathy that it is a mere symptomatic method, ctc., I have already alluded to and refuted. I now let the more important ones of the rest follow, and you will con- stantly find, that they originate out of ignorance or malice." 1. "Homœopathy is the grave of science, as it neither re- quires Anatomy, Physiology, nor Pathology, etc., because it merely confines itself to the outward signs of disease, with- out trying to arrive at its cause and nature." The former letters have, however, proved to you that Homœopathy exacts all these sciences as absolutely necessary. But, you know also, that it only sanctions in all of them those laws of nature which have been ascertained by pure ex- periment and unprejudice dobservatiou; and that Homœo- pathy banishes, as it were, completely those which have been invented by mere speculation and hypothesis, and forced unto nature. You, moreover, know that it com- prises all these sciences, and that, out of an organic germ, it develops an organic science, which makes us acquainted with the true objective, and not with the invented subjective laws and manifestations of life; and that, going from the external to the internal, it tries to determine and lay hold of the processes of both healthy and diseased life, so far as the light of facts does reveal, but not as subjective opin- ions create it. It is, therefore, an organic science, which is based upon facts, that are the result of experiment and observation, an impression of nature itself, and an orga- nic combination and mutual penetration of its laws, and, teaching only these, it creates a true objective knowledge and opposes in a decisive manner all the notions, specula- tions, and hypotheses of so-called rational medicine. As 300 certain as Chemistry dug a grave for Alchemy and As- tronomy made one for Astrology, so assuredly does this true organic science prepare one for so-called rational medicine, which, in reality, is but an arbitrary science, re- plete with hypotheses and error, and, in this sense, it is one of the greatest distinctions for Homœopathy, that it is the grave of a science which is full of illusions. The following is an extract from the letters of one who was cured by Homœopathy:-" Homœopathy is not a system in this sense (the arbitrary subjective), it is not the admiration of the healthy and the fear of those who require help, the pride of the novice, and the confusing recollection of the experienced physician- it is not one of those works of art, which start from the most comprehensive survey and stop before the most con- fined opinions, which start at the cradle of life, and too often terminate at the grave of the patient. It is not a school system, like the theories of excitation and of counter-irritation, not like the vampirism, before alluded to, of the French, who, in much after the same way as that of extinguishing a candle to get rid of the thief, tap off the blood to quieten it. It does not resemble one of our national philosophical visions, with the spheres of sensibility, irritability, and nutrition, and their medical and political equilibrium in the small kingdom of man. Led by experience, HAHNEMANN pursued his way step by step. A series of observations led him to the common cause of all single experiences of a certain kind. They taught him, in all cases of the not to be doubted curative action of a remedy, to distin- guish, among a number of accidental and changeable conditions, exactly that one which, returning unchanged in all of them, must be considered as an indication and 301 characteristic of the curative power of this remedy. They, it is true, did not show him how diseases and remedies might be judged from the very beginning, nor that this could be done after single manifestations; but how the symptoms of the one and the effects of the other, should be examined in their ensemble, and how the application of the latter is governed by the results so obtained.” Is the objective, real scientific nature of Homœopathy, not clearly described in these words; and do they not con- tain the conclusive refutation of the false accusation, that this mode of treatment is not scientific? A short time after the above remarks were written, Dr. RUMMEL spoke in the following manner about this reproach :-" Far from waging a war of destruction against science, Homoeopathy only wants to recognise that which is true, and banish all CONJECTURES out of it. We will not deny the expe- riences of Allopathy, as soon as they stand the test of real experience, but we will elucidate their explanations and hypotheses; we do not wish to combat the useful- ness of this mode of treatment in all cases; but we want to show where physicians, unlike Hippocrates, did not observe Nature, but did disturb it, where they TALKED about the curative power of nature, and suppressed with a coarse hand its very efforts of cure; where they talked about causal indications, and in spite of this cured symp- tomatically, we want to show them how little rationalism exists behind high-sounding phrases; how true rationality is a recognition of the limits which here confine us, how the laws of things, but not their causes are discernible. "" You see opponents have had sufficient opportunity for instruction. But they hide their head in ignorance, as the ostrich hides its head in the sandheap, when unable to escape from the hunter. But, just as little as such an 302 act saves it, so little will this ostrich-trick of Allopathy save it from the near grave, which true objective science digs actively for the subjective pseudo one. 2. The cures under homeopathic treatment are not oc- casioned by it, but through faith and the power of ima- gination." This might be indeed possible with persons who are capable of belief, and who are possessed of strong imaginative power, although the same opponents say again, in another place, that they had never seen that the greatest confidence in a medicine had ever done the least good-a most singular contradiction! But how will these gentlemen explain the cures made by Homœo- pathy in cases where there can be no question of either belief or power of imagination, I mean in children who are yet too young for belief; in certain patients with a diseased mind, where consciousness is completely gone, as in some cases of Typhus, and lastly, in animals? must seem truly astonishing to our adversaries, how, in all these cases, Homœopathy could cure, and how, in these instances, it actually realises the most brilliant re- sults. Do sick animals also get better by believing in Homœopathy or by their imaginative power? Or have these sceptical opponents suddenly become so very cre- dulous, as to fancy that quadrupeds and horned cattle cannot exist without faith? Be careful that these four- footed animals, by the faith reposed in them do not one. day grow impudent enough to believe that they also have a right to believe! Perhaps such animals might then take it into their heads to believe that they are without horns and mistake others for themselves. It Is this not enough to prove to opponents how dange- rous it is to base their judgment respecting Homœopathy upon so loose a ground as belief and imagination; and 303 will they not in future think it wiser to judge it by facts only? I doubt it. They will remain obstinate, like the adversaries of VESAL, who, in opposition to him, maintained that the anatomical plates of GALEN were made after the aboriginal type of the human race, and, therefore, the sole correct ones, and that VESAL'S were only got up after men had changed their aboriginal type. It was, however, afterwards proved that Galen had never dissected auy human bodies at all, but had taken those plates from monkeys. The learned opponents, there- fore, preferred being a bastard genus of the species mon- key, than that Vesal should be in the right versus Galen. It is my opinion, that every interpretation is here super- fluous so let us proceed! 3. "The cures that have taken place under homœopathic treatment are all caused by the curative power of nature.” I at once ask of opponents why they do not avail them- selves of this power, and why they still continue to tor- ture suffering humanity with drugs which, in the massive doses which they prescribe, endanger both health and life, impoverish the purse considerably, and, according to the Statistical Reports, do not furnish anything like the favour- able results obtained by homoeopathic treatment. How can they any longer justify bleeding, blistering, purging and other weakening modes of treatment? How defend the long list of powders, pills, and mixtures, the mere thought of which makes you shudder? MORITZ MULLER says very appropriately to such people :-" If it were the healing power of nature which would have cured, even without the administration of Homœopathic remedies why don't you then allow it to cure a disease in a cheap and easy manner? How can you believe in the curative power of nature, when, in every casc of illness, you write. 304 out prescriptions; which is a proof that you do not trust to it, or that you consider your prescriptions more effi- cacious? How can you ever ascertain the curative power of nature when you never allow it to work? It is to you a vis incognita (an unknown power), and yet, by appealing to it, you wish to upset us, who entirely act in the spirit of Hippocrates, who, according to the nature of our treatment must know that power better than you. Supposing it were the curative power of na- ture which effected all the homœopathic cures, then you possess not sufficient intelligence to prove it, and it is not to your credit, that you find fault with that which is better and more in accordance with nature than your own mode of treatment. 4. "Diet only accomplishes the cures which happen un- der Homœopathic treatment." But with sick infants, who have not even been weaned, as well as sick animals, no particular change does happen with regard to their diet. Other sufferings are so severe, of so acute a nature, that patients cannot take any food at all whilst so afflicted; this happens also where there is entire loss of appetite. In all these cases, there can be no question of a peculiar diet. In addition hereto, come the cures of severe chro- nic ailments, against which the Allopathic treatment had been tried in vain for years, and which happened after the administration of Homœopathic remedies, notwithstanding that no system of diet had been observed at all. Our opponents, by supposing that the successful cures of Homœopathists were caused by diet, give a sorry tes- timony of poverty to their own modes of treatment. Is it possible, that this old school of medicine, which by preference calls itself the rational one, could in more than 2000 years not find a proper diet! HAHNEMANN 305 had to be waited for! And if in truth HAHNEMANN'S diet occasions the cures, why do these opponents not introduce it also to their patients; and, save them the tortures of dreadful mixtures and powders, as well as the literal exploration of their pockets, when the cures so obtained are, according to the Statistical Reports, far fewer in number than those obtained by homoeopathic treat- ment? In addition to this theoretical question, we men- tion the following facts: GRIZOLLE, BIETT, and SKODA have treated their patients for a certain time without any medicines. The result was more favourable than under Allopathic treatment, less favourable than under Homœo- pathic treatment. The medical schools of Vienna and Prague, the chief seats of medicine, have, through a tendency towards pathological anatomy, accustomed themselves to a more moderate and objective comprehension; and have, in con- sequence of this, given up all hypothetical and dogmatical sentences of Patbology and Therapeutics, and adopted the expectative (do-nothing) method. They have proved, by means of statistical reports, that the present (Allo- pathic) clinical therapeutical maxims, with all their different methods and remedies, furnish less favourable results than the expectative method, as Dr. DIETL, senior physician to the District Infirmary of the Faubourg Wieden, in Vienna, has numerically proved in the treat- ment of inflammation of the lungs. He, in the years 1842-48, treated 380 individuals, suffering from primary inflammation of the lungs. Of these 85 were bled and 106 were treated with large doses of tartarus emeticus, whereas 189 had merely their diet regulated. The following table will give you the result of— X 306 Cured Died Rate of mortality Bleeding. Antim. tart. Diet. 68 84 175 17 22 14 20.4 20.7 7.4 Proper diet cured the severest cases of inflammation of the lungs without the least expence in three weeks, and the deaths amounted only to 7.4 per cent.; whereas, by bleeding, 20.4; and, by large doses of tartarus emeti- cus, 20.7 died. Hear further: In 99 cases of inflamma- tion of the lungs, which Dr. REIS treated in the Linzer Homœopathic Hospital, in the years 1843 up to 1848, only 1 death took place-thus a mortality of 1 per cent. In the Gumpendorf Hospital of the Sisters of Charity in Vienna, out of 284 patients, treated homeopathically by Dr. FLEISCHMAN, and suffering from pneumonia. during the years 1844-48, only 10 died-thus a mor- tality of 331 per cent. Consider also that these results, which were obtained by the expectatire as well as the Homeopathic treatment, occurred in the same year, and almost in the same locality, viz., Vienna, so that there can be no question of a mild or severe epidemic, of a good or bad locality, with either mode of treatment. If you compare the numbers 204, 207, 74, 33, you find, that under the expectative method there were 13 deaths less out of every hundred than under bleeding, and under the administration of tart. emet., aud that there died 17 less under the Homœopathic treatment than under bleeding and tart. emet., aud about 1 less. than under the expectative method. What results from all this? That the expectative method is far superior to that of the Allopathic bleeding and administration of tart. emet., but that both are surpassed by the results of the Homœopathic treatment, and that those of the 307 latter are truly POSITIVE. Therefore, Homœopathists, unlike the physicians of the expectative method, arc not condemned to play the sad part of mere idle observ- ers, but they actually, as real practical physicians, ap- proach the bed of the patient. 5. “Homœopathy injures by doing nothing; for, though it is not directly injurious with its sugar globules, the injury, in many instances, is all the greater by neglecting proper succour.” succour." Yea, a Professor went so far as to wish Homeopathists to be brought before the tribunal and see them condemned for these sins of omission. Let us again look to numbers. From the com. parison of Statistical Reports it is clear, that mortality under Homœopathic treatment averages from 4-5 per cent., under Allopathic treatment from 10-13 per cent.; under Homœopathic treatment of cholera 8, under Allopathic treatment 51 and 67 per cent.; under Homœopathic treatment of pneumonia 31 per cent., under dietetic treatment 74, and under Allopathic treat- ment (by bleeding and tart. emet.) 20 and 20 7 per cent. The dietetic method, therefore, does nothing; the cxpectative, directed by the cleverest physicians in Vienna and Prague, saves therefore out of every 100 patients the lives of 13, and Homœopathy the lives of 17 more out of every 100 patients than Allopathy does by bleed- ing and administering tart. emet.; and, in cholera, from 43 to 58 persons more die out of every hundred under the Allopathic than under the Homoeopathic treatment. The proportion has therefore completely changed; for, you see, that under the so called do-nothing of Homœo- pathy, not ouly no lives are lost, but 17 patients are cured more than under Allopathic treatment, and 4 more than under the expectative method. In cholera, Homœopathy cven saves the lives of 43 to 58 patients 308 more out of 100 than Allopathy. The multifariousness of the Allopathic treatment with bleeding, tart. emet., etc., etc., allows, therefore, in pneumonia, 17 patients out of every 100, and in cholera, from 43 to 58 patients to die more than the so-called do-nothing of Homœo- pathists. Let me ask of you, who now does more harm: the Homœopathist, with his globules and accused neglect of the proper succour-namely, bleeding, tartar emet., etc., or the Allopathist, with all his interfering violent treatment? And if there can be any question at all of being brought before a Court of Justice, who is then the guilty party? Assuredly he who, by his treatment, does POSITIVE harm; therefore, not the invented sins of OMISSION—but those that are really COMMITted. 6. "Homœopathists only administer one and the same remedy in all diseases." This accusation is all the more readily believed, because Homoeopathic remedies are generally given in so small a dose, that the different drugs can no longer be distinguished by the senses; and that one remedy, be it diluted with spirits of wine, or in the form of either trituration or globule, looks quite like the other, having neither smell nor taste. But if these sagacious gentlemen were only to examine a Homœopathic medicine case, or open a Homœopathic Pharmacopoeia, they would soon find that Homœo- pathy possesses just as many different, and, for the most part, the very same remedies as those which the Allopathists have, only that they administer them in a simple manner and after different principles. As every- body can convince himself by his own eyes of the truth of this, this accusation is unfounded, and falls to the ground, like all the others. But admitted that Homœo- pathists actually did with one remedy succeed in mak- 309 ing so many successful cures, as statistics prove, then I think that our opponents ought not to lose a single minute in appropriating this precious and won- derful panacea which is so openly and freely offered to them in all Homoeopathic writings, and administer it without delay to suffering humanity. 7. "The Homœopathic remedies are powerful poisons?" Let it not astonish you if the respectable opponent, who thus accuses Homœopathy to the one patient, imme- diately afterwards ridicules its remedies as containing nothing at all, as being inefficient. being inefficient. For here, as I have already formerly said, it matters little what the in- trinsic value of the reasons may be, provided they answer the purpose. If they only succeed in deceiving patients as regards the REAL NATURE of Homœopathy, all has been attained that can be desired, and it is the same thing whether this is brought about by accusing the former of practising with poisons, or of doing nothing at all. I have already spoken to you about this do-nothing system; but, as regards the practice with poisons, what do you say? Is it not just and right, that every-one should first sweep before his own door? There are many dark, nay, blood-red pages in the chapter of poisoning of the old school of medicine. I have already communicated to you some remarks which refer to it, and which were made by the first authorities of Allopathy. I here add what the distinguished Physician PETER FRANK has said:- "That medical police is more directed against that which is public, against contagious epidemics, charla- tans, and quacks; but that it has not been considered, that in the quiet sick-chamber thousands are gradually sacrificed, and that it amounts to the same whetherGovern- 310 ment loses its subjects by single or by different disea- ses." (Syst. of Med. Police, Vol. I, Introduction, page 6.) And remember also what SCHULZ says:-" More persons are destroyed by the interference of medical men than are saved by it." Do you wish for more; then read the essay by KRÜGER HANSEN: "Homoeopathy and Allo- pathy in the Scales." He, upon the basis of facts, has drawn the most dreadful picture of the ravages which Allopathy has committed from time immemorial amongst humanity. The objection, that such things only happen to imprudent and unprincipled physicians is not sound. I only remind you of BROUSSAIS' Vampirism, of the excessive doses of mercury prescribed by the followers of BROWN, the large doses of iodine given by physicians of the first rank; and, instead of the numerous cases I could adduce, I will only relate the following one. In the month of May, 1828, a physician in Bicêtre, Paris, prescribed Prussic acid to fourteen epileptic patients, who composed a ward which had been en- trusted to him, and that in such a dose that seven of the unfortunates (that is to say all who had taken the infer- nal draught) died almost immediately afterwards under convulsions; the first died, happily, when the seventh had hardly swallowed the poison, whereby the others were saved. Now let it be well understood, that this was not the fault of the carelessness of a single madcap, who held a Doctor's diploma, but of the united wisdom of the medical authorities, who watched over the safety of public health, for this poisoning was got up after a for- mula contained in the beginning of the Paris Codex (V., Clinique des Hospitaux Parisiens, T. ii., No. 66, FRORIEF'S Notes, No. 441). *This treatment seems of late to have sprung up again. Note of Translator. 311 Do you believe that the like does not happen in the present day? Every day you may meet with young and old persons with decayed, loose, or even false teeth; and who has presented them with these? The mercury (ca- lomel) which in their youth was administered to them, when suffering from inflammation of the lungs or croup, and which was prescribed in continued large doses, un- til the teeth got loose and the cavity of the mouth was covered with purulent ulcers of a truly carrionlike smell. I will not even mention the blooming FULL-BOSOMED girls, who by iodium have and still become pale, ca- chectic, and FLAT-BOSOMED. Fortunately for these poor creatures, there are yet clever dressmakers, who by their art try to restore the faults of medical men and so prevent public scandal. In the face of such facts would it not be more advis- able if opponents never pronounced the words of poisonous practice? I here again ask them to convince themselves by examining a homœopathic medicine-case, when they will find that the homoeopathic remedies, with a few exceptions, are almost from the same source as those of Allopathy. There exists, therefore, between the poisons of Homeopathy and of Allopathy no other difference than thut Homœopathists prescribe them in small, very small, yea even in the smallest, the Allopathist, on the contrary, in very large, doses. I will quote one of the strongest poisonous arsenics as an example. The SMALLEST dose of the Allopaths, on an average is from 3 to 7 of a grain the GREATEST of Homeopathists regularly 10000 0000 grain, the SMALLER and SMALLEST one of the 12, 30, 200, 400, &c., trituration, according to the homeopathic mode of preparing medicines. The numbers speak too palp- ably and indicate too plainly, if there is a question at all 30 100 312 of poison, where the danger lies, whether, with the small and smallest doses of Homœopathists, or with the by far greater and large doses of Allopathists, and thus the accusation of poisoning rebounds on the accusers. That, however, such small and smallest doses of Homœo- pathists produce no poisoning effect is proved by pota- toes, white turnips, the leaves of cabbages, the ripe straw, all of which, according to most recent analyses, contain arsenic in such small and smallest doses, and are daily eaten by men and animals as healthy food, without the least symptoms of arsenical poisoning show- ing themselves. Similar quantities of arsenic are con- tained, according to WALCHNER, in all mineral springs, which thousands of patients drink in great quantities. every year, and without ever a symptom of arsenical poisoning showing itself. From this you see that the strongest poison, in a wise and proper dose, ceases to be a poison, and Homœopathists know the method and make use of it to transform, by a wise preparation and diminution, the strongest poisons into the most curative remedies.. 8. "The diet of Homœopathy is a hunger-cure." Let us examine its regulations: Homœopathy wants to re- gulate the patient's mode of life in such a manner, so as to promote thereby the treatment. It insists, therefore, on the removal of all errors in the diet, which either have engendered the disease, or still keep it up. It allows the patient to take as much food as is necessary, therefore, as much as is required to replace the loss occasioned by the continuous change of matter. From this it results, that, in cases where this change of matter has become slower, less food must be taken; but where the contrary to this takes place, more in pro- 313 portion. But this measure of consumption may and must not be surpassed, for all that is in excess cannot be used in nutrition, and becomes therefore superfluous, it does impede the functions, and is therefore a cause of disease. It is clear, that those aliments are most suitable to accomplish this, which contain substances, that either by direct means or by digestion can replace the waste of matter; therefore, Homœopathy insists that these should be taken in preference, and does not require those which, besides being food, possess also medicinal properties. It therefore prescribes real articles of food in the truest sense of the word. It forbids only those ingredients which possess medicinal properties, because the effect of the given remedy is either entirely or partly disturbed, and the clinical observation obscured thereby. The effect of the remedy must be, however, a most possibly pure, complete and undivided one, and, therefore, Homœopathy advises, that, to nourish the body, food only, and not medicines should be used; a perfectly just and natural wish; and for this very reason, comprehen- sible to everybody who does not forcibly shut his ears against the voice of nature. As the articles of food are only to replace the waste of matter, and as in every in- dividual instance the change of matter differs, it results that there cannot be any absolute dietetic rules which are valid in all cases, but that they are to be regulated according to each individuality. Here, as everywhere, the law of individualising must be attended to, and Homœopathy, which has this law inscribed on its stand- ard, expresses itself as follows in its rules on diet:- Offer to the patient as food that which is qualitatively fit in each case, that which corresponds and agrees with his individuality and present state, therefore, that which 314 is dietetically similar; because this can only replace the wasted matter, and become itself a part of the organism, without causing hurtful secondary effects. Homœopathy thereby maintains the organic process of life at its utmost height and energy. It fulfils, therefore, the highest philosophy of diet. cure. In acute, or so called feverish, diseases, there can hardly be a question of proper food; for such patients have, in most instances, little or no inclination for it at all. It is therefore wise to pay attention to this indication of nature, and to restrict the patient's diet to that which is absolutely necessary. Against every surplus, patients generally show their disgust-a striking proof that they are not hungry, or, that they are not undergoing a hunger- The above given rules on diet are generally observed by Homœopathists in chronic diseases; but instinct and habit retain their privilege. On this ac- count, no considerable change or restriction is to be made as regards diet, as the most dangerous chronic diseases are cured without. But this does not forbid Homœopathists insisting seriously on the removal of the creating and maintaining cause of the chronic ailments. as well as of all that might interfere with the action of the remedy or possess medicinal properties. For this reason they forbid wine, brandy, liquors, strongly spiced ingredients, tea, strong spiced beer, and coffee, which is often the cause of chronic ailments of the stomach. When taking aconite, wine and acids are forbidden; when taking belladonna, coffee, because these stand in an antedotal sense to each other, and therefore neutralise their mutual effects. For this very reason, Homœo- pathists forbid, if they wish to work upon certain orgaus, all kinds of food, which exert a specific influence 315 upon the functions of these organs; for which reason, asparagus, parsley, celery, &c., are forbidden when remedies are prescribed against diseases of the kidneys and bladder, that the functions of these organs may not be disturbed; but kept in the fullest suscepti- bility for the action of the remedy. It is quite certain that it will then better develop its effects and furnish purer results to the observer, than when disturbed by the simultaneous action of other ingredients. On ac- count of this interfering with the action of the remedy, strong scents, incense, aromatic washes, most tooth- powders, composed of various ingredients, in parti- cular those of china and camphor, are forbidden. Homœopathists, so far from forbidding that which is necessary, recommend chiefly the more nutritious kind of food, such as the meat of full-grown animals fed in the open air, in preference to that of the unnatural fat meat, which has been obtained by fattening animals in stables, or that of new-born animals and very young poultry; therefore, in general, no fat pork and other kind of fat meat, salted meat, too young veal, richly prepared vegetables, &c., but well roast or boiled beef, mutton, poultry, game, eggs, fish; with a few exceptions, broth, most sorts of vegetables, plain puddings, cocoa, milk, &c. In addition to this, the partaking of harmless things is allowed, for diet is not to be rendered difficult by unnecessarily forbidding things; but the cure is to be promoted by appropriate nourishing articles of food, which are free from medicinal properties. Even those things which are generally forbidden, are allowed if the body has become accustomed to them, if it would be unusually excited through not receiving them, or if its reactive power has become so weakened, that every 316 remedy remains without effect. In such cases, the mo- derate use of wine, coffee, tea, &c., is not only not for- bidden, but absolutely necessary to promote the cure. Thus, constantly considering the change of matter and the reactive power of the body, Homœopathists only follow up the requirements and hints of nature, and wisely give their dietetic rules, equally free from troublesome pedantry and untimely flexuosity and subserviency. These are, therefore, no arbi- trary laws got up according to the chemical physical properties of bodies, or formed and modelled according to our own inclinations and habits; but laws which have been obtained by the objective contemplation of organic nature, which exacts the most nourishing articles of food that will at all times replace the waste of matter in the most complete manner, and so form the best safeguard against hunger-the perceptible want of matter. Homœopathists are never forced to condemn their patients to the most dreadful pangs of hunger, by depriving them of the necessary food to replace the waste of matter, as is the case in the frightful hunger-cures of Allopathy. On the contrary, they, in every case, pre- scribe the most nourishing diet, and only an ignoramus or slanderer can speak of a homoeopathic hunger-cure. As far back as the year 1832, the Secret Councillor, Dr. KOPP, in Hanau, spoke as follows:- "The Homœopathic diet has been called a very meagre one, nay, even a hunger-cure; but this is not so, inasmuch as in most cases, it ordains that all kinds of nourishing things, such as meat, broth, eggs, chocolate, &c., should be moderately partaken of, without being too severely restrictive as regards the quantity." But opponents have eyes and do not see, and cars and do 317 not hear. However, they may consider that the truth is heard by other people; and that the day is not far off when it will resound in their ears in no pleasant and gentle manner. 9. "Homœopathy has been tried by physicians, and found to be untrue." If an opinion is to be given about a point, it is necessary, first of all, to have an intimate knowledge of it. This intimate knowledge is also indis- pensable with regard to the investigation of Homœopathy; and, as its result is a theoretical and practical one, its trial demands, besides the most exact theoretical know- ledge, also practical experiment, undertaken in a sensible and candid manner. Opponents, therefore, who, in their study, try to refute the theoretical part, and endeavour to prove the impossibility of Homoeopathy by all sorts of arbitrary representations, by sophistic tricks, are unable to give an opinion, because they have not paid any atten- tion to the more essential, viz., the practical part. Their heads are, moreover, so filled with the inorganic, hypothe- tical, subjective mode of viewing things, of Allopathy, that they are not at all able to comprehend the organic, objective idea which pervades Homœopathy. They see through their allopathic-stained glasses, and maintain that Homœopathy is stained like their spectacles-a mistake which they will only find out when they put their spec- tacles aside, and, with undeceived look, view things as they really are, and not as the stained-glasses make them appear. If bad-will is added to this, you can easily guess what you may expect from such experimenters. The practical experiments even show still greater superficiality, shallowness, and dishonesty; and therefore must prove abortive; for, as the practice of Homœo- pathy exacts so careful an organic study of all medical 318 sciences and in its treatment, the most careful organic realisation of this knowledge in each separate case of disease; as, moreover, the organic comprehension of mcdicine is only possible when all old inorganic views are thrown overboard; you can easily conceive that this is not the work of a few days or weeks; that it is not sufficient to have read merely the one or the other homœopathic work, and to proceed then immediately to experiment. Such a proceeding naturally offers the saddest results, which do not terminate in the exposure of Homœopathy, but in that of the experimenter. All such experiments bear the brand of insufficiency, imma- turity, and malevolence on their very brow; I re- peat immaturity, for one does not become a good Homœopathist in a few months; no, not even can the most learned Allopath, though opponents would so gladly make the public believe that such is actually the case; it is the work of many years of serious and deep study. Most physicians who experiment with Homœopathy without possessing a thorough knowledge of it, proceed in the same spirit as when they try a newly re- commended remedy, without having an exact knowledge of the same, and naturally with the same wretched 1e- sult. Such experiments, as well as the opinions which physicians of all classes, natural philosophers, medical counsellors, nay, entire colleges, have expressed about Homœopathy, prove clearly that these gentlemen know everything except what they require to know. the organic-individual law of nature in its entire compass and entire depth. Unfortunately, something morally worse is often added to ignorance. I merely remind you of what Dr. MÜHLENBEIN says on the subject. I mean The essential conditions of Homœopathy-those of 319 • adhering to that which is organically individual—are wanting throughout all these experiments. This is es- pecially the case with those made by Dr. ANDRAL, of Paris, which are in every respect so devoid of the least merit, that every novice in Homœopathy would be ashamed of them; they have also been severely criticised by several parties. I myself have experienced, that a "Physician tried to exterminate Homoeopathy by giving to all his patients, without exception, a grey powder (ink and sugar of milk triturated together). Should not such a experimenter, instead of refuting him, be forced to swallow ink himself?" However mean and ridiculous such proceedings are, they do not fail in their effect on the public, who are, for the greater part, ignorant of the real nature of me- dicine, and regulate their opinions after that of their medical attendants, whom they are accustomed to con- sider competent judges. To be competent, however, in- timate knowledge and practical ability are required; both of which are wanting in allopathic physicians, with regard to Homœopathy, as its inorganic-individual contents is quite different from the inorganic-generalising one of Allopathy. Though both systems have the same aim, viz., that of curing diseases; yet, their ways, means, and modes of attaining this end differ completely, and a fol- lower of Allopathyis, therefore, no more justified in giving his opinion of or to judge Homœopathy,than the captain of a sailing vessel is a fit judge of a steamer, merely be- cause both carry passengers and goods; or will a good coachman, without any further teaching, make a good engine-driver? I full well know what your answer and that of every rational person will be; I also know that you and every rational person will only recognise theo- 320 retically and practically educated men to be competent judges of Homœopathy, and that the sacred duty which every citizen owes to suffering humanity and to the great objective law of nature, on which Homœopathy is based, will cause you to repulse all frivolous and ma- licious intruders. I here have put before you the main objections and abuses which are preferred against Homœopathy, and have completely refuted them. As a matter of course, there are still more of them; and new ones will in the present and future certainly be devised. You, who now understand the real and true nature of Homœopathy, will, by an unprejudiced comparison, immediately re- cognise their futility, and share with me the conviction that all these arrows which have been shot off either by ignorant or malicious persons, will rebound powerless like the others from the mailed breast of truth which pro- tects Homœopathy. Would that opponents, instead of wasting their time in such useless and hateful endeavours, might sweep before their own door, and cleanse the chaos of all the trash, in which even the last spark of organic science threatens to go out! If Homœopathists wished to make objections and insinuations, or to raise complaints, you know they need not INVENT and devise them! Everywhere objective material can be FOUND IN DENSE MASSES for this purpose! It would form a small Blue Book; and rest assured, that in spite of all sophis- tical defence, the unbiassed and impartial judge would more than once pronounce the sentence of "Guilty." How can Allopathy venture, under existing circumstances, to question, make insinuations, or condemn Homoeo- pathy in an arrogant manner? And self-respect will not permit, that Homœopathy, like 321 a serving and modest hand-maid, which opponents would wish to make of it, should watch anxiously and appre- hensively the looks of Allopathy, of Allopathy which, devoid of every organic law, is doomed to the most dis- graceful servitude of the most arbitrary hypotheses and speculations, whilst Nature herself has, through its or- ganic law, created Homœopathy a free Queen. Dr. JOCHMANN is perfectly right, when he says, in alluding to the objections which have been made against this organic science, "I do not know whether it is absolutely required to be a physician, to raise such objections; but it is quite apparent to me, that one need not be one to be ashamed of them." Y LETTER XIX. THE SELF-DISPENSING OF HOMOEO- PATHISTS. I HAVE NOW come to the golden apple which the Goddess, very soon after the birth of Homœopathy, threw among the assembled Homoeopaths, Allopaths, and Chemists. Time exacts, that it should not roll any further, but that it should, on the contrary, be stamped into a coin, which creates confidence and guarantees to us, the regeneration of suffering humanity. This will occur so soon as Homœopathic physicians are no longer threatened to have the right of dispensing taken from them, or that this is allowed to them merely as a special favour; but when it shall be recognised that they are duly entitled to this right, and shall be assured that they may carry it out in an unmolested manner. If a method is recog- nised, the only means through which it can prosper, must be sanctioned also. At every moment, physicians must be able to satisfy themselves of the genuineness of the remedy which they are about to prescribe; if not, they are totally unable to take proper care of their patients, as conscience bids them to do, or of forming 323 an idea about the efficiency or inefficiency of the medi- cines prescribed. The inefficiency of a drug may always give rise to the question:-Was it inefficient, on account of being wrongly selected, or because it was not genuine, or has, perchance, not a wrong medicine been given by mistake instead of the real one? In this manner, physicians cannot possibly make reliable observations and experiences; they can, therefore, neither verify the present results of Homœopathy, nor attend to its further scientific development. Conviction of the genuineness of the prescribed medicines is absolutely re- quired for every method. Homœopathists, however, can only have it by preparing and dispensing the medicines themselves. They generally prescribe them, in the ma- jority of cases, in such triturations or dilutions, that it is either entirely impossible to prove their material exis- tence, or, if this can be done in the lower attenuations, the successive attenuations cannot be exactly distinguished the one from the other. The certain hair-splitting limits in both are, however, of the greatest importance in practice. It is also necessary that these medicines should not be prepared and kept in places where the atmosphere is filled with the vapours of drugs; for in such a case they cannot be relied on. Only by observing the effects of drugs on the healthy and diseased organism, the certi- tude of their genuineness can be obtained, and such ob- servations fall only to the sphere of the physician. Government can therefore never undertake to procure for the public proper and reliable homœopathic remedies through chemists, as it quite impossible to control them. The first and most essential intention of Govern- * * Dr. STENS alludes to allopathic chemists, who, in some in- stances, make up homeopathic prescriptions. 324 ment, as regards the law respecting chemists, becomes therefore questionable. If this intention is to be carried. out to its fullest extent, homoeopathic physicians only are entitled to prepare their medicines, because they alone are able to decide by observations on the healthy body whether they are genuine or not. The free un- checked development of science and the welfare of all citizens who entrust their lives to Homœopathy, prove the self-dispensing of Homœopathists a necessary in- violable right, and a necessary consequence of homœo- pathic practice. Hence it results, that it is the most sacred duty of Government to recognise this right of Homœo- pathy, and to enforce it by law. There can be no ques- tion about any infraction of the privileges of apothecaries. They, from the very commencement, were subjected to the severest control of the medical authorities; and, as this is impossible with homoeopathic remedies, these monopolies, for this very reason, cannot be extended to Homœopathy. Besides they are logically and gram- matically strictissima interpretationis, and therefore only to be applied to the medicamenta officinalia, which are prepared after the rules of the old school of medi- cine, and, according to the opinion of all lawyers, can- not be extended to a discovery, which was not made at the time these privileges were granted. In a legal point of view, our dilutions are no medicines at all, as there are no rules laid down for their preparation in any official Pharmacopoeia. In accordance with the laws of the country, Homœopathists allow chemists to dispense the crude drugs, as this forms part of their privilege. Thus no real privilege of the apothecary is infringed, if physi- cians prepare and dispense the homœopathic medicines themselves. But, let us admit, for a moment, that these 325 privileges were entirely or partly annulled by self- dispensing, does it then not sound fabulous that in our present important time, when so many historically firm- based privileges give way to progress, that Government does not, in this case, relinquish its rights of making re- forms suited to the spirit of the age, and that it would rank the private interests of apothecaries above those of the general welfare of humanity and science! Truly, such a belief may remove mountains, but it will not stay the onward cause of progress, and therefore be un- able to prevent any arrangements it may require! For it is clear, that apothecaries exist on account of patients, but the latter not for the former. Sanitary Councillor RUMMEL says, We do not deny that the livelihood of apothecaries is very much endangered by the self-dis- pensing of Homoeopathists. But this is the fate of all institutions which have outlived themselves, entirely or partly; and though we do not deny our regret to the said profession, we should find it very unjust to tax citizens, and, in particular, the poor suffering part of them, for the maintenance of apothecaries; and it would amount to this, if, for the welfare of chemists, patients were forced to pay dear for the medicines which the physician gives them equally good, and for nothing; nor can Allopaths complain that Homœopaths are hereby pri- vileged. There can only be a question of preference where more than one have a right to a thing; and seeing that under the same circumstances it is given to the one, and denied to the other. The question arises, therefore, here:-Have Homeopathists and Allopathists an equal right to dispense remedies themselves? Taking the matter in an absolute manner, we answer with a direct Yes. And this the more so, as hereby the inven- 326 tions and discoveries of the physician are secured to him as property, a right to which he is equally entitled with every other citizen. If we, however, look into the history of medicine, we find that already, in former times, the number of medicines required had so increased, that their mixtures had become so complicated, and the mode of procuring them so expensive, and their preparation. required so much time and money, that the physician was unable to attend to all this, besides his usual avocations. Government then divided the labour, and created the apothecaries with their privileges, thinking that medicine would thus be practised in the best manner possible. To be sure it was always a delicate affair between two evils—the one of entire ruin, the other of a neccs- sarily limited income-to have to choose the latter, the lesser one, and we do not envy the position in which Allopaths are placed through this, for it renders their observations very difficult, nay, often quite uncertain. We rejoice, however, to find, that the very reasons which caused Government to take away from Allopathic Physicians the right of dispensing their medi- cines themselves, obliges them to grant it to the Homœo- paths. With Homoeopathy, medicine has entered upon a phase, where it must take back the ancient and sacred right of self-dispensing, which, for the welfare of suffer- ing humanity it had been obliged to hand over for a time to the apothecary. Thus the disparity of the circumstances of both methods renders the disparity of the treatment necessary, so that each may enjoy its perfect development and practical execution; and without being unjust towards itself, and the higher idea of Government, the one cannot complain about a privilege. being granted to the other. Under these circumstances, 327 it is evident, that, even if the results of both systems were alike, that the homeopathic treatment offers a greater advantage to the poor, and that, consequently, the phy- sician who is a follower of this system will have a greater call of patients than his Allopathic colleague. This circumstance has often created bad blood, and mightily assisted those who complained about being slighted, and that privileges were accorded to Homœo- pathy. We can only see a proper recognition in it such as every progress deserves, and wish, from the bottom of our hearts, that these complainants may soon enjoy the same advantages, by simplifying their system in a similar manner. We wish this all the more, as suffering humanity in general, and the poor in particular, would derive bene- fits herefrom. For the cheapness of medical assistance, derived from the self-dispensing of homeopathic phy- sicians, is of such great importance, both to the individual patient, as well as to the Government, that we cannot help repeatedly calling the attention of the Ministers of Finance to this important point. It is quite in accordance with the maxim of self-administra- tion of the present time, viz., that what ONE class can do, should not be done by Two. How easy it is for Homœopaths (on account of the small quantities) to carry the medicines in their pocket, and to administer them without the least loss of time, which, in a country practice, is of the greatest importance. What shall we reply to the objections that have been raised against self-dispensing? That which is granted to Homœopaths should be granted also to every other me- dical practitioner. Assuredly, if it be proved to be a necessary consequence for the completion of the one or other mode of practice, and if it agrees with the higher 328 Now, Or, idea of Government (to perfect the mode of practice). We have already discussed this claim before. to the next objection :-By granting the right of self- dispensing to physicians, they are no longer under the control of the medical authorities, and especially of that of the Apothecaries; and the poisoning and quackery of non-medical men are hereby encouraged. We, in turn, ask, who controls the apothecaries? Or should we be foolish enough to believe that an inquiry which happens once in every year, and often only once in three years, is a sufficient guarantee to us? Such a thing is too fabulous to be believed. The honesty of the apothe- cary alone can be our guarantee. But, since when have Physicians become less honest than apothecaries? is perhaps the higher scientific education of Physicians, which Government exacts, a reason to enjoy less confi- dence than apothecaries do? It has been firmly be- lieved until now, that, under like circumstances, superior education went hand in hand with a more developed morality. If physicians do not choose to avail them- selves of this advantage, they, at all events, have a right to claim the same amount of confidence that is placed in the apothecaries. We shall reject with indig- nation every attack on this sacred right of the physician; and we expect that our colleagues will do the same, let them belong to what school they may. But if physi- cians and apothecaries are equally honest, and if we consider that the physician's conduct is determined by the interest he takes in science, and in the welfare of his patients, and the reputation which depends on his cures, whereas that of the chemist can only be a purely mercantile one, and that, in most instances, he is again to depend on his assistants; then, the question: From whom may we expect the most reliable medicines? from 329 the apothecary or the physician? is readily answered. This is the easier with regard to Homoeopathists; for their very simple and inexpensive remedies* require neither the knowledge the many compound mixtures do, nor the technical routine, through which a division of labour arose, and on account of which apothecaries were created. The conclusion is, that, if poisoning and encouragement of quackery is feared from physicians, chemists are more liable to commit such errors, and that it is against all reason to make the latter the over- lookers of the former. With regard to Homœopathists, we must once more remind you of that which we have already mentioned on a former occasion, namely, that no control is possible, on account of the small doses, either on the part of the medical authorities over apothecaries and physicians, or of apothecaries over physicians. Add to this injudiciousness and foolishness of controlling in general, the impossibility of examining and testing the medicines through chemical or any other means. To this comes the collision which the apothe- cary, whose income is considerably lessened by Homœo- pathy, has to stand between official duty and that of providing for his family, as well as his general unbelief in the efficacy of small doses. So it stands with the control. In spite of it, the morally bad physician can find means sufficient to carry out his wicked plans and elude the surveillance of the apothecary. "If Govern- ment wishes to avoid the afore-named evils completely, let it then provide" as Surgeon-Major Dr. GRIESSELICH so well expresses himself, "thoroughly well-educated physicians, and give them a suitable status; then it will require no policemen and gens-d'armes, spies, or * If Dr. STENS lived in expensive England, he would not thus underrate labour.-TR. 330 informers, through whom they are only held in fear and hypocrisy, but are not placed in that position that is due to their responsible avocations. I believe that I have proved, by this explanation, that the self-dispensing of remedies is a necessary consequence of Homœopathy; and, moreover, the right it has of being recognised by all governments. I will finally draw your attention to the fact, that Bruns- wick, Prussia, and Weimar have made this right dependant upon a certain examination; that Austria has recognised the principle of giving medicines gratuitous- ly, that in the Grand-Duchy of Darmstadt and in the Duchy of Meiningen the self-dispensing of homœopathic physicians has been permitted; and that in Würtemberg every physician who asks for it obtains permission to dispense his own medicines. Besides this, most German Parliaments have duly considered this subject, and pro- nounced themselves in favour of it. LETTER XX. SURVEY OF HOMEOPATHY-ITS POSITION -WHAT HAVE HOMEOPATHISTS TO DO? I have endeavoured to place before you the true and faithful portrait of Homœopathy. You have learned that it was brought to light by genuine experiment, and repeated objective observation. On these two foundation pillars, the sole ones of every true physical science, the structure of Homœopathy is based; and on its portals we find inscribed the maxim of "similia similibus curantur "; a law which has been discovered in nature and not invented by mere speculations. This maxim never sanctions any preference or dismembering in its execution; it exacts that life must be conceived in organic unity. All option and hypotheses cease to have a scientific value; only pure objectiveness. -facts-may lay a claim to it. They must be com- prehended in their organic combination with a mind devoid of prejudice, progressing from the external to the internal, illumined with the light of facts, and not with the will-o'-the-wisp of hypothesis. In doing so, it 332 1 < is absolutely necessary to consider the different mani- festations of life independently by themselves, that each takes its standard only from itself, so that they never appear in a determining, but only in an explana- tory manner, the one for the other. They subordinate themselves to uniform life; from which they receive their laws, and the separate sciences of Physiology, Pathology, Materia Medica, and Therapeutics, carried as it were by the organic unity, and specially stamped by it, form here the true organic science of medicine. It develops itself from an organic germ, comprises all its mem- bers in organic association, and, acquainting us in this manner with the laws of the manifestations of life, which have been ascertained by experiment as well as by objective observation, it teaches us at the same time the means to maintain healthy life, and to lead back to health that which is suffering under disease. And for this it is only qualified by its real natural philoso- phic method, which recognises as laws only the answers of nature itself, and not the cerebral reflections of the specula- tive mind. For this reason they are as firm as nature itself, and do not bend to the arbitrary dogma of notions and hypotheses, through which, until now, an organic science of medicine, and, therefore, natural philosophic therapeutics have become impossible. With it, the reign of old hypothetical systematics is at an end, and that of facts, with the laws thereby revealed, commences. No scholastic dogma, therefore, hinders and enslaves the mind and will which observe the laws of nature only. Banished is the philosophical spirit of falsehood, which in artificial systems builds castles out of mere ostenta- tious suppositions. Here we no longer have the rational law of cure, of subjective inclination, but the true rational 333 one of objective necessity. Here the laws of nature must be ascertained, for all hypotheses are forbidden. Here, not as in the old school of medicine, castles in the air arise as if by magic; but the firm structure of medicine is built out of slowly matured observations. And because Homœopathists in this manner only act in accordance with the objective laws of nature, they receive the hand- some reward of realising the artificial cure, this noblest and highest problem of the physician, and that in con- tinually increasing perfection, the further they proceed in the objective perception of nature on the road of facts. They thus by deeds prove the falseness of the much resignation affecting the assertions of Allopathic physi- cians, that the entire science of medicine is incapable of altering in an essential manner the rate of disease and mortality. Let opponents turn and twist in whatever way they choose, the actual cures are too brilliant, and the statistics speak with too weighty numbers in favour of Homœopathy thus, that the system of negation could any longer be persisted in. In the same degree, that it sur- passes Allopathy in real scientific precision, so does it also exceed it in successful practical results. DR. M. Müller said some years ago :-" Homœopathy has, in the brief span of its career, advanced further than the old school of medicine in 25 centuries: it is even now based on a more scientific foundation than the latter. And all through its own powers, easily developed by experience, experiment, and observation, in spite of all obstacles, and discouragement on the part of Government. Notwithstanding the combined efforts of thousands of physicians, for the most part clever men, the old school is unable to advance as a practical science, which on account of its brilliant position, it ought to have done, IF 334 IT WERE POSSESSED OF THRIVING GERMS, but mere empty husks, dead heaps of stone are grown together with its immovable frame, and it is even INFERIOR to the snail, which at all events carries its own shell with it. And how is Allopathy fostered by Government in spite of all this, with what princely munificence are not millions wasted upon it! Does it not possess professorial chairs, hospitals, and dispensaries more than enough? Are not all official posts and privileges held by its fol- lowers ? What enormous expenses are saddled on Government and the parishes by its military and civil. medical institutions; and does not the tribute which those who are treated allopathically pay to physicians. and chemists amount to as much, and in some families even to still more, than all the remaining Government taxes? Are not thousands abandoned thereby to misery and death; and is Government in this way not deprived of many truly excellent powers? And if Homœopathy now, instead of developing hypotheses, does develop a real Science; if its practical execution furnishes the most brilliant results, and thereby saves to Government the lives of thousands of citizens; if it frees them from the most pressing and heaviest tributes, in so far as health and money are concerned; if, moreover, it saves considerable sums for the most praiseworthy undertakings; if it has hereby paved a way for itself, in spite of all obstacles, and enjoys the confidence of numerous rich and poor: is it then right that those privileges and rights which Allopathy possessed for a length of time, should still be held back from it? Privileges and rights, in the enjoyment of which Allopathy drags its sickly existence along. Does Govern- ment not suffer by such a state of things quite as much as every individual citizen? How can it be brought in 335 unison with the idea of Government, according to which, the spiritual and bodily welfare of every citizen is to be cared for, and the right guaranteed to him to entrust himself, as he thinks proper, to the one or the other treatment, and thereby choose for himself the means of recovering and maintaining health? And are not the citizens who entrust themselves to Homœopathy violated in this right? Are they not for the greater part in want of homoeopathic physicians, because for the simple reason, everywhere homœopathic schools are wanting, because from no professorial chair are its contents taught and its practical value shown, whereas from many such places it is daily condemned for the greater part by ignorant and malicious opponents. To tolerate Homœopathy it is not sufficient to meet the ends of justice; but all direct im- pediments must be removed and the indirect ones changed into direct encouragements. In this manner only will it receive the vital conditions for its development, which Government, for which it has become a question of life, on account of its high inward perfection and out- ward propagation, may no longer withhold from it. Homœopathy, which has raised medicine to a true phy- sical science, must be recognised and treated as a free legitimate daughter of natural philosophy. For this, are, above all, required a professorial chair and a clinical hospital, as publicity develops, in both of them, the most essential and most beautiful blossoms of this method, and so will best remove the contempt and fear whereby students, partly through ignorance, and partly on purpose, are prejudiced against it. If the student can examine and observe, the sacred right of investigation is preserved to him, and the door is shut to all malicious slander. His becoming acquainted with this excellent method docs then no longer depend on mere chance, as 336 has been hitherto and is still the case, to the great pre- judice of suffering humanity. Through this observation and examination, he is enabled to make himself familiar with the true contents of Homœopathy, and is able to choose which course he will adopt in future. Thus Government fulfils the sacred duty, which is incumbent on it, with regard to the health of the daily increasing numbers of citizens, who are anxious to entrust them- selves to Homœopathy, a duty which Government has only performed in a very hostile way; for, by erecting and protecting suitable institutions, Government provides them with physicians who are acquainted with Homœopathy. Or shall clinical lectures, in future, be obliged to teach old fashioned views and practice accord- ingly? Will it henceforth be permitted to dismiss a pro- fessor because he examines Homeopathy, that he may at last arrive at some natural philosophic therapeutics, as has been recently the case with Professor RAPP in Tübingen? May clinical hospitals continue to be training establishments whicre future physicians are in- structed in the principles of the old school practice of medi- cine, a practice, the ground of which is sandy, and the pil- lars of which are rotten, a practice that has been relinquished by its most eminent men, who have even condemned and stiy- matised it? Is it not the sacred duty of the clinical teacher to cure the patients in his institution as speedily, easily, and cheaply as he can, and to teach his pupils to become self-dependent, free investigators, and so impart to them the greatest possible certainty in prac- tice? Shall it any longer be said of universities, that they impede the development of many branches of knowledge? Shall clinical hospitals still longer merit the reproach, that they oppose the scientific liberty of investigation 337 belonging to physicians? Will medical faculties and Government authorities, in future, not show so much scientific sense, that they will never sanction any proposal to confine academical clinical hospitals to fixed forms and suppress the free investigation of clinical physicians ? The Austrian Government has already done this in a most praiseworthy manner, by establishing two pro- fessorial chairs and two clinical hospitals, the one in Vienna and the other in the University of Prague, whereby its legitimacy has been recognised. May we not expect, with right, from the scientific zeal of the present time, and the high importance of the point at issue, that other governments also will speedily follow this meritorious and just example? Will they not (if they do not give them a preference) place the real philosophic Therapeutics, of which Homœopathy now alone represents their purest and most perfect expression, on an equal footing with the Therapeutics of arbitrary hypothesis? If not, ought they not then, for the sake of consistency, to place the nonsensical alchemists and the astrological knaves on the professorial chair, and, instead of the established laws of chemistry and astro- nomy, allow the bombastical oracles of falsehood, of magic, and witchcraft to be heard? Let it not be said, as authorities have done before, that a professorial chair was never denied to Homœopathy; that the homoeo- pathic physician had only to enter formally on the office of an academical teacher. We ask, on the contrary: By whom is the facultas docendi, the admission to teaching given? By a college of professors, composed only out of Allopaths, the greater part of whom consider Homœopathy mere heresy, and, as examples sufficiently prove, try to suppress it as much as possible. On account of the differing, yes, almost entirely differing points of view, Z 338 they declare the labour of the Homoeopathist to be un- scientific of course, because it denies their supposed hypothe- tical knowledge, and replaces it by a true positive one. In this respect, medicine may be compared to religion; and the similarity of both, as regards their confession, be kept in view. Just as much as Roman Catholics and Pro- testants have their converging and diverging points, through which latter the creed characterises itself. most decidedly; just as much are there between Ho- mœopaths and Allopaths familiar and diverging points; and, through the latter, both methods of cure appear in quite as decided separate characteristical forms- as medicial confessions; the vouchers for this asser- tion I have sufficiently communicated to you. How unjust, nay, how ridiculous would it be, if the facultas docendi for Roman Catholics were to be given by a college of Protestant professors, or, vice versa. I think such a matter requires no commentary, it speaks for itself. I am of opinion, that it requires just as little comment to see the preternaturalness that Homœopathy, in its present high internal development and widely spread recognition, should receive from Allopathy the facultas docendi for the erection of a homeopathic clinical hospital. You will agrce with me that Homœopathists must decidedly decline such an offer. This would be chaining Homeopathy to the chariot of Allopathy, that it might, if possible, drag the hated here- tic around the walls of Troy. There exists a history of Homœopathy; and I have already divulged the contents of many a page of it to you, and shown you the intrigues and prosecutions which this method of cure has been, and is, subject to. I only remind you of Professor RAPP, who was deprived of his office merely because he also tried Homeopathy. But what must await him who recognises 339 this doctrine as the sole natural philosophic Thera- peutics, and practises accordingly? After such expe- rience, Homœopathists are, as a matter of course, not foolish enough to allow themselves to be festooned as victims. To maintain science, therefore, pure and undese- crated, they must insist that the professorial chair and the homœopathic clinical hospital shall be determined and car- ried out by those who have an intimate knowledge of it, there- fore, by recognised clever homœopathic physicians, under the due protection of Government. But to maintain the existence of Homœopathy in a sound and healthy state, a professorial chair and a clinical hospital are not the only requirements; all regulations, laws, etc., must correspond with its innermost nature and value, and emanate from medical authorities, who are Homœopathists themselves, who, through their legal qualifications can be recognised as competent. I call your attention to the fact, that Homœopathic Pharma- cies are inspected by natural philosophers and apothe- caries who have by no legal qualification proved their know- ledge of Homœopathy, and who, having no intimate know- ledge of it, cannot be considered competent judges by the law. Nevertheless, they report upon Homœopathic phy- sicians who possess this legal qualification, they who have no intimate knowledge, who are not qualified, report upon those who have this intimate knowledge, who are quali- fied-athing evidently and totally the reverse of what it should be, and assuredly without a parallel in any other administration. It requires but little wisdom to see that such inspection ought only to be undertaken by those who have a thorough knowledge of Homœopathy, therefore, by legally empowered qualified Homeopathic physicians. Or, do you think that, were a casc of midwifery on trial, Government would 340 appoint a physician who did not possess the legal quali- fication of accoucheur, one, therefore, who had no inti- mate knowledge of it, though his knowledge of diseases. and surgery be first-rate? Never! Just the same rela- tion exists here with regard to Homœopathy. All matters belonging to it can and ought only be judged by legally qualified Homoeopathic, and not Allopathic Physi- cians. This is one of the NECESSARY AND VITAL CONDI- TIONS of Homœopathy, which must be granted to it, if it is not to appear in an undeveloped and crippled state. May these and similar regulations have arisen through ignorance or the malicious calculation of making the new method ridiculous and detested-they are adverse to scientific development and to art, as well as to a just and proper taking care of health in accordance with the laws of nature; they must, therefore, be an- nulled, and replaced by others which are conformable to nature and suitable to science and art. Government must the sooner do away with these drawbacks, as through these disadvantages which befall Homœopathy the great and daily increasing number of citizens, who entrust themselves to this mode of treat- ment suffer. And on account of this increasing confi- dence Homœopathists must strive to obtain, besides the scientific equality, also the same political right which the old school possesses, so that their mode of treatment, even from without, stand pure and unimpeached. They desire, there- fore, that IIomeopathy be represented at all boards of health by one or more homeopathic physicians, who in case of any offence being committed by a homœopathic physician will have to judge these questionable cases. It is but too well known what mighty influence the Government insti- tutions have upon the development of every science and 341 re- art. Nor is it less known that such institutions can only happen, and happen far sooner, if experts and men animated with love and zeal for the science have a seat and vote in the administration of the government. How hostilely Homœopathy has been treated by Government in conse- quence of the want of such persons, how this supposed heresy has been insulted, persecuted, and hindered in its development by the so-called recognised school of medi- cine; all this stands written in too indelible characters in the history of Homœopathy to require that I should r peat it here. That which I have already communicated to you will furnish you with sufficient examples. But involuntarily the expression escapes us :-"There must come a change!" At the boards of health, homoeopathic physicians who take care of and further the development of Homœopathy must be present. That is a reason for such a requisition on the part of science; and another on the part of the administration of justice. This acknowledges everywhere only COMPETENT authorities; this right may therefore, no longer be withheld from Homœopathists. They may no longer, on account of their practice as Ho- mæopathic physicians, whether they appear as accusers or accused, be brought before and punished by an authority which has not proved that it is competent to judge, very much less one which has proved itself the enemy of this doctrine! In all cases where transgressions occur in Homœopathic practice, Homœopathists will and must only be judged by experts, that is, by a medical council composed of Homœopathic Physicians. This request is such a just one, that I consider it superfluous to add a single word. Bavaria has already recognised it, and carried it into effect by ordaining that a Homoeopathic Physician has a vote and seat at each medical council. 342 The other governments will soon follow, in no longer de- clining a matter which is so just and so closely and essen- tially connected with the welfare of the country. Until this scientific and political equality of birth takes place, it is the duty of Homœopathists to unite and resist firmly and constantly the oppression which threatens them from all sides. They must make valid the power of truth without fear, with scientific seriousness, and with dig- nity. They must constantly show, that they teach and practise a firm and reliable science of experience, instead of the old one replete with suppositions, and that they, there- fore, cannot permit the free organic law of nature to be subservient to the law of arbitrary invention, because it would be treason against truth and nature. They must in- struct those who are ignorant with love and clearness. But if the most cunning sophistries are delivered with a sweet voice under the mask of high respectability, and when such words diffuse themselves like poison among the well-edu- cated and reading public, and thence fall like mildew upon the people,—then gentleness must cease, then truth must be spoken with fiery tongue, and the actual execution of the same must follow blow after blow, until the rotten walls of the old temple of hypotheses and dogmatic edifice of medicine, which phy- siology continually undermines, shall be shaken till no stone is left upon the other! For it concerns a high and sacred cause-the welfare of millions! And if quietness seems to reign now and then, it is not the calmness of peace, it is the stillness before the thunderstorm, which constantly growls in a threatening manner, and which, on the first opportunity, throws forth its lightning. It needs only one regulation to the detriment of Homœopathy and look at the satis- faction of the adversaries. Only one unsuccessful case of the Homeopathist, although it is clear that the fault 343 is by no means attributable to him, and see the rejoicing and hear the spiteful interpretations, only one slander- ing article in any official journal, and what satisfied self- complacent nodding of the head do we observe. Homœo- pathisis must, therefore, be watchful and prepared for battle, and well versed in words and deeds, and whilst they build with the one hand the temple of Homœopathy out of actual cures higher and higher, they with the other must grasp the sword of the word, ready to defend or attack, as faithful representatives of truth are bound to do. They must combat not to spill blood, but to preserve it. They must teach humanity the value of one of its most precious possessions, namely, health, so that those who disseminate unfounded vituperations, shall be struck dumb by the force of truth, and that the eyes of the public be opened by it. They must continually show that all arguments respecting the untruth or nonentity of Homœopathy result from the wish, and the conviction of opponents, that it might be so arising therefrom, but not that this conviction is the result of proof. And about this there can be no doubt, if its true character is clearly and distinctly pointed out, a character which is founded solely upon experiment and objective observation, and thence derives its laws, and makes the all-complete organic conception an irremissible duty, admitting only facts in the disclosure of the inward state of life, and therefore comprising a real natural philo- sophic system of medicine, in the truest sense of the word. Before concluding, I remember the words which we uttered many years ago:— "A thousand ways cross through life; choose one, little matters which, if only firm integrity and tested strength dwell within your breast." Here is the path which I have taken and the manner 344 in which I have walked it. Judge! I do not say that I have completed a work more lasting than bronze; but I know and feel, that a living act has detached itself from me with all the inspiring prolific strength and consecra- tion which truth bestows, and firmly trust, that in you, and in others also, it will live and prove its blissful power. UNIVERSITY OF MICHIGAN 3 9015 06827 5513 Filmed by Preservation 1990